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1345982-69-5,MFCD28386358
Catalog No.:AA009C95

1345982-69-5 | Gsk2330672

Pack Size
Purity
Availability
Price(USD)
Quantity
  
2mg
98%
in stock  
$156.00   $109.00
- +
5mg
98%
in stock  
$267.00   $187.00
- +
25mg
98%
in stock  
$902.00   $632.00
- +
100mg
98%
in stock  
$1,537.00   $1,076.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA009C95
Chemical Name:
Gsk2330672
CAS Number:
1345982-69-5
Molecular Formula:
C28H38N2O7S
Molecular Weight:
546.6755
MDL Number:
MFCD28386358
SMILES:
CCCC[C@@]1(CC)N[C@H](c2ccccc2)c2c(S(=O)(=O)C1)cc(c(c2)OC)CNC(CC(=O)O)CC(=O)O
Properties
Computed Properties
 
Complexity:
870  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
2  
Heavy Atom Count:
38  
Hydrogen Bond Acceptor Count:
9  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
13  
XLogP3:
-1.6  

Literature

Title: Discovery of a highly potent, nonabsorbable apical sodium-dependent bile acid transporter inhibitor (GSK2330672) for treatment of type 2 diabetes.

Journal: Journal of medicinal chemistry 20130627

Title: Wu Y, et al. Discovery of a highly potent, nonabsorbable apical sodium-dependent bile acid transporter inhibitor (GSK2330672) for treatment of type 2 diabetes. J Med Chem. 2013 Jun 27;56(12):5094-114.

Title: Wang Y, et al. HNF4α Regulates CSAD to Couple Hepatic Taurine Production to Bile Acid Synthesis in Mice. Gene Expr. 2018 Aug 22;18(3):187-196.

Title: Linerixibat (GSK2330672) granted Orphan Status. September 24, 2019.

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SDS
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Tags:1345982-69-5 Molecular Formula|1345982-69-5 MDL|1345982-69-5 SMILES|1345982-69-5 Gsk2330672
Catalog No.: AA009C95
1345982-69-5,MFCD28386358
1345982-69-5 | Gsk2330672
Pack Size： 2mg
Purity： 98%
in stock
$156.00 $109.00
Pack Size： 5mg
Purity： 98%
in stock
$267.00 $187.00
Pack Size： 25mg
Purity： 98%
in stock
$902.00 $632.00
Pack Size： 100mg
Purity： 98%
in stock
$1,537.00 $1,076.00
Quantity
- +
Add to Card
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bulk Quotation Request
Technical Information
Catalog Number: AA009C95
Chemical Name: Gsk2330672
CAS Number: 1345982-69-5
Molecular Formula: C28H38N2O7S
Molecular Weight: 546.6755
MDL Number: MFCD28386358
SMILES: CCCC[C@@]1(CC)N[C@H](c2ccccc2)c2c(S(=O)(=O)C1)cc(c(c2)OC)CNC(CC(=O)O)CC(=O)O
Properties
Complexity: 870  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 2  
Heavy Atom Count: 38  
Hydrogen Bond Acceptor Count: 9  
Hydrogen Bond Donor Count: 4  
Rotatable Bond Count: 13  
XLogP3: -1.6  
Literature fold

Title: Discovery of a highly potent, nonabsorbable apical sodium-dependent bile acid transporter inhibitor (GSK2330672) for treatment of type 2 diabetes.

Journal: Journal of medicinal chemistry20130627

Title: Wu Y, et al. Discovery of a highly potent, nonabsorbable apical sodium-dependent bile acid transporter inhibitor (GSK2330672) for treatment of type 2 diabetes. J Med Chem. 2013 Jun 27;56(12):5094-114.

Title: Wang Y, et al. HNF4α Regulates CSAD to Couple Hepatic Taurine Production to Bile Acid Synthesis in Mice. Gene Expr. 2018 Aug 22;18(3):187-196.

Title: Linerixibat (GSK2330672) granted Orphan Status. September 24, 2019.

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