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Home Other Building Blocks 1312445-63-8
1312445-63-8,MFCD27923138
Catalog No.:AA009CB6

1312445-63-8 | NVP-BKM120 (Hydrochloride)

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
in stock  
$218.00   $153.00
- +
10mg
in stock  
$325.00   $228.00
- +
100mg
in stock  
$1,093.00   $765.00
- +
  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA009CB6
Chemical Name:
NVP-BKM120 (Hydrochloride)
CAS Number:
1312445-63-8
Molecular Formula:
C18H22ClF3N6O2
Molecular Weight:
446.8545
MDL Number:
MFCD27923138
SMILES:
Nc1ncc(c(c1)C(F)(F)F)c1cc(nc(n1)N1CCOCC1)N1CCOCC1.Cl
Properties
Computed Properties
 
Complexity:
530  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
30  
Hydrogen Bond Acceptor Count:
11  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
3  

Literature

Title: Burger MT, et al. Identification of NVP-BKM120 as a Potent, Selective, Orally Bioavailable Class I PI3 Kinase Inhibitor for Treating Cancer. ACS Med Chem Lett. 2011 Aug 26;2(10):774-9.

Title: Zheng Y, et al. Novel phosphatidylinositol 3-kinase inhibitor NVP-BKM120 induces apoptosis in myeloma cells and shows synergistic anti-myeloma activity with dexamethasone. J Mol Med (Berl). 2012 Jun;90(6):695-706.

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SDS
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Tags:1312445-63-8 Molecular Formula|1312445-63-8 MDL|1312445-63-8 SMILES|1312445-63-8 NVP-BKM120 (Hydrochloride)