[1]CurrentPatentAssignee:ROCHEHOLDINGAG-US2010/222325,2010,A1Locationinpatent:Page/Pagecolumn59-60
[2]Lou,Yan;Han,Xiaochun;Kuglstatter,Andreas;Kondru,RamaK.;Sweeney,ZacharyK.;Soth,Michael;McIntosh,Joel;Litman,Renee;Suh,Judy;Kocer,Buelent;Davis,Dana;Park,Jaehyeon;Frauchiger,Sandra;Dewdney,Nolan;Zecic,Hasim;Taygerly,JoshuaP.;Sarma,Keshab;Hong,Junbae;Hill,RonaldJ.;Gabriel,Tobias;Goldstein,DavidM.;Owens,TimothyD.[JournalofMedicinalChemistry,2015,vol.58,#1,p.512-516]
[1]JournalofMedicinalChemistry,2015,vol.58,p.512-516
[1]Lou,Yan;Han,Xiaochun;Kuglstatter,Andreas;Kondru,RamaK.;Sweeney,ZacharyK.;Soth,Michael;McIntosh,Joel;Litman,Renee;Suh,Judy;Kocer,Buelent;Davis,Dana;Park,Jaehyeon;Frauchiger,Sandra;Dewdney,Nolan;Zecic,Hasim;Taygerly,JoshuaP.;Sarma,Keshab;Hong,Junbae;Hill,RonaldJ.;Gabriel,Tobias;Goldstein,DavidM.;Owens,TimothyD.[JournalofMedicinalChemistry,2015,vol.58,#1,p.512-516]
[1]Lou,Yan;Han,Xiaochun;Kuglstatter,Andreas;Kondru,RamaK.;Sweeney,ZacharyK.;Soth,Michael;McIntosh,Joel;Litman,Renee;Suh,Judy;Kocer,Buelent;Davis,Dana;Park,Jaehyeon;Frauchiger,Sandra;Dewdney,Nolan;Zecic,Hasim;Taygerly,JoshuaP.;Sarma,Keshab;Hong,Junbae;Hill,RonaldJ.;Gabriel,Tobias;Goldstein,DavidM.;Owens,TimothyD.[JournalofMedicinalChemistry,2015,vol.58,#1,p.512-516]
[1]JournalofMedicinalChemistry,2015,vol.58,p.512-516
Title: Bruton's tyrosine kinase inhibitors: approaches to potent and selective inhibition, preclinical and clinical evaluation for inflammatory diseases and B cell malignancies.
Journal: Journal of medicinal chemistry 20120524
Title: RN486, a selective Bruton's tyrosine kinase inhibitor, abrogates immune hypersensitivity responses and arthritis in rodents.
Journal: The Journal of pharmacology and experimental therapeutics 20120401
Title: Potent and selective inhibitors of Akt kinases slow the progress of tumors in vivo.
Journal: Molecular cancer therapeutics 20050601
Title: Xu D, et al. RN486, a selective Bruton's tyrosine kinase inhibitor, abrogates immune hypersensitivity responses and arthritis in rodents. J Pharmacol Exp Ther. 2012 Apr;341(1):90-103.
Title: Hsu J, et al. Bruton's Tyrosine Kinase mediates platelet receptor-induced generation of microparticles: a potential mechanism for amplification of inflammatory responses in rheumatoid arthritis synovial joints. Immunol Lett. 2013 Feb;150(1-2):97-104.
Title: Mina-Osorio P, et al. Suppression of glomerulonephritis in lupus-prone NZB × NZW mice by RN486, a selective inhibitor of Bruton's tyrosine kinase. Arthritis Rheum. 2013 Sep;65(9):2380-91.
