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1431697-90-3,MFCD19443231
Catalog No.:AA009CBX

1431697-90-3 | SB-408124 Hydrochloride

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
98%
1 week  
$138.00   $97.00
- +
10mg
98%
1 week  
$193.00   $135.00
- +
50mg
98%
1 week  
$508.00   $355.00
- +
100mg
98%
1 week  
$781.00   $547.00
- +
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  • Technical Information
  • Properties
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Technical Information
Catalog Number:
AA009CBX
Chemical Name:
SB-408124 Hydrochloride
CAS Number:
1431697-90-3
Molecular Formula:
C26H24N2O
Molecular Weight:
380.4816
MDL Number:
MFCD19443231
SMILES:
CCC(c1ccccc1)NC(=O)c1c(C)c(nc2c1cccc2)c1ccccc1
Properties
Computed Properties
 
Complexity:
484  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
27  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
3  

Literature

Title: Langmead et al (2004) Characterisation of the binding of H-SB-674042, a novel nonpeptide antagonist, to the human orexin-1 receptor. Br.J.Pharmacol. 141 340.

Title: I Tissen, et al. OX1R ANTAGONIST SB408124 ACTION AND EXTRAHYPOTHALAMIC CRF IN RATS AFTER PSYCHOTRAUMATIC EXPOSURE. Georgian Med News. 2019 May;(290):127-131.

Title: Michael J Huber, et al. Increased activity of the orexin system in the paraventricular nucleus contributes to salt-sensitive hypertension. Am J Physiol Heart Circ Physiol. 2017 Dec 1;313(6):H1075-H1086.

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SDS
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