Home Other Building Blocks 1402601-82-4
1402601-82-4,MFCD26142679
Catalog No.:AA009CCH

1402601-82-4 | Tug-770

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$53.00   $37.00
- +
5mg
≥98%
in stock  
$230.00   $161.00
- +
10mg
≥98%
in stock  
$405.00   $283.00
- +
25mg
≥98%
in stock  
$883.00   $618.00
- +
100mg
98%
in stock  
$3,027.00   $2,119.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA009CCH
Chemical Name:
Tug-770
CAS Number:
1402601-82-4
Molecular Formula:
C19H14FNO2
Molecular Weight:
307.3184
MDL Number:
MFCD26142679
SMILES:
N#CCc1ccccc1C#Cc1ccc(c(c1)F)CCC(=O)O
Properties
Computed Properties
 
Complexity:
523  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
23  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
6  
XLogP3:
3.5  

Downstream Synthesis Route

[1]Christiansen,Elisabeth;Hansen,SteffenV.F.;Urban,Christian;Hudson,BrianD.;Wargent,EdwardT.;Grundmann,Manuel;Jenkins,Laura;Zaibi,Mohamed;Stocker,ClaireJ.;Ullrich,Susanne;Kostenis,Evi;Kassack,MatthiasU.;Milligan,Graeme;Cawthorne,MichaelA.;Ulven,Trond[ACSMedicinalChemistryLetters,2013,vol.4,#5,p.441-445]

Literature

Title: Development and Characterization of a Potent Free Fatty Acid Receptor 1 (FFA1) Fluorescent Tracer.

Journal: Journal of medicinal chemistry 20160526

Title: Discovery of TUG-770: A Highly Potent Free Fatty Acid Receptor 1 (FFA1/GPR40) Agonist for Treatment of Type 2 Diabetes.

Journal: ACS medicinal chemistry letters 20130509

Title: The role of biotransformation in the action of drugs affecting the sympathetic nervous system.

Journal: International anesthesiology clinics 19750101

Title: Christiansen E, et al. Discovery of TUG-770: A Highly Potent Free Fatty Acid Receptor 1 (FFA1/GPR40) Agonist for Treatment of Type 2 Diabetes. ACS Med Chem Lett. 2013 May 9;4(5):441-445.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Related Products of 1402601-82-4
Tags:1402601-82-4 Molecular Formula|1402601-82-4 MDL|1402601-82-4 SMILES|1402601-82-4 Tug-770