Name: Name:Ha 130
Brand: AABLOCKS
SKU: AA009CFH
Rating: 90 (10 reviews)

Catalog No.: AA009CFH

1229652-21-4 | Ha 130

Pack Size： 5mg

Purity： ≥98%

in stock

$103.00 $72.00

Pack Size： 10mg

Purity： ≥98%

in stock

$185.00 $129.00

Pack Size： 25mg

Purity： ≥98%

in stock

$255.00 $178.00

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Technical Information

Catalog Number: AA009CFH

Chemical Name: Ha 130

CAS Number: 1229652-21-4

Molecular Formula: C24H19BFNO5S

Molecular Weight: 463.2858

MDL Number: MFCD20926343

SMILES: Fc1ccc(cc1)CN1C(=O)S/C(=C\c2ccc(cc2)OCc2cccc(c2)B(O)O)/C1=O

Properties

Complexity: 722

Covalently-Bonded Unit Count: 1

Defined Atom Stereocenter Count: 0

Defined Bond Stereocenter Count: 1

Formal Charge: 0

Heavy Atom Count: 33

Hydrogen Bond Acceptor Count: 7

Hydrogen Bond Donor Count: 2

Isotope Atom Count: 0

Rotatable Bond Count: 7

Undefined Atom Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0

Downstream Synthesis Route

1229652-27-0

137660-67-4

1229652-21-4

[1]Locationinpatent:experimentalpartAlbers,HaraldM.H.G.;VanMeeteren,LaurensA.;Egan,DavidA.;VanTilburg,EricaW.;Moolenaar,WouterH.;Ovaa,Huib[JournalofMedicinalChemistry,2010,vol.53,#13,p.4958-4967]

Literature fold

Title: Discovery and optimization of boronic acid based inhibitors of autotaxin.

Journal: Journal of medicinal chemistry20100708

Title: Zhang Y, et al. Autotaxin through lysophosphatidic acid stimulates polarization, motility, and transendothelial migration of naive T cells. J Immunol. 2012 Oct 15;189(8):3914-3924.

Title: Bai Z, et al. Constitutive lymphocyte transmigration across the basal lamina of high endothelial venules is regulated by theautotaxin/lysophosphatidic acid axis. J Immunol. 2013 Mar 1;190(5):2036-2048.