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1281870-42-5,MFCD18794648
Catalog No.:AA009CH9

1281870-42-5 | Rhosin (hydrochloride)

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
≥98%
in stock  
$80.00   $56.00
- +
10mg
≥98%
in stock  
$152.00   $106.00
- +
25mg
≥98%
in stock  
$316.00   $221.00
- +
100mg
98+%
in stock  
$448.00   $314.00
- +
250mg
98+%
in stock  
$726.00   $508.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA009CH9
Chemical Name:
Rhosin (hydrochloride)
CAS Number:
1281870-42-5
Molecular Formula:
C20H19ClN6O
Molecular Weight:
394.8575
MDL Number:
MFCD18794648
SMILES:
O=C([C@@H](Cc1c[nH]c2c1cccc2)N)N/N=C/c1ccc2c(c1)nccn2.Cl
Properties
Computed Properties
 
Complexity:
541  
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
1  
Defined Bond Stereocenter Count:
1  
Heavy Atom Count:
28  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
5  

Literature

Title: Shang X, et al. Rational design of small molecule inhibitors targeting RhoA subfamily Rho GTPases. Chem Biol. 2012 Jun 22;19(6):699-710.

Title: Shang X, et al. Small-molecule inhibitors targeting G-protein-coupled Rho guanine nucleotide exchange factors. Proc Natl Acad Sci U S A. 2013 Feb 19;110(8):3155-60.

Title: Francis TC, et al. The Selective RhoA Inhibitor Rhosin Promotes Stress Resiliency Through Enhancing D1-Medium Spiny Neuron Plasticity and Reducing Hyperexcitability. Biol Psychiatry. 2019;85(12):1001-1010.

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SDS
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Tags:1281870-42-5 Molecular Formula|1281870-42-5 MDL|1281870-42-5 SMILES|1281870-42-5 Rhosin (hydrochloride)