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1393124-08-7,MFCD30343861
Catalog No.:AA009CJT

1393124-08-7 | glucagon receptor antagonists-4

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98+%
in stock  
$19.00   $14.00
- +
5mg
98+%
in stock  
$46.00   $32.00
- +
10mg
98+%
in stock  
$68.00   $48.00
- +
25mg
98+%
in stock  
$115.00   $81.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA009CJT
Chemical Name:
glucagon receptor antagonists-4
CAS Number:
1393124-08-7
Molecular Formula:
C26H28F3N3O4
Molecular Weight:
503.5134
MDL Number:
MFCD30343861
SMILES:
CCC[C@@H](c1ccc(cc1)C(=O)NCCC(=O)O)Oc1cc(C)c(c(c1)C)n1ncc(c1)C(F)(F)F
Properties
Computed Properties
 
Complexity:
718  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
36  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
10  
XLogP3:
5  

Literature

Title: Esther C.Y. Lee et al. Identification of a novel conformationally constrained glucagon receptor antagonist. Bioorg Med Chem Lett, 2014 Feb 1, 24(3):839-44.

Title: Derek J Nunez, et al. Glucagon receptor as a drug target: A witches' brew of eye of newt (peptides) and toe of frog (receptors). Diabetes Obes Metab. 2018 Feb;20(2):233-237.

Title: D J Kazierad, et al. Effects of multiple ascending doses of the glucagon receptor antagonist PF-06291874 in patients with type 2 diabetes mellitus. Diabetes Obes Metab. 2016 Aug;18(8):795-802.

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SDS
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Tags:1393124-08-7 Molecular Formula|1393124-08-7 MDL|1393124-08-7 SMILES|1393124-08-7 glucagon receptor antagonists-4
Catalog No.: AA009CJT
1393124-08-7,MFCD30343861
1393124-08-7 | glucagon receptor antagonists-4
Pack Size： 1mg
Purity： 98+%
in stock
$19.00 $14.00
Pack Size： 5mg
Purity： 98+%
in stock
$46.00 $32.00
Pack Size： 10mg
Purity： 98+%
in stock
$68.00 $48.00
Pack Size： 25mg
Purity： 98+%
in stock
$115.00 $81.00
Quantity
- +
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Technical Information
Catalog Number: AA009CJT
Chemical Name: glucagon receptor antagonists-4
CAS Number: 1393124-08-7
Molecular Formula: C26H28F3N3O4
Molecular Weight: 503.5134
MDL Number: MFCD30343861
SMILES: CCC[C@@H](c1ccc(cc1)C(=O)NCCC(=O)O)Oc1cc(C)c(c(c1)C)n1ncc(c1)C(F)(F)F
Properties
Complexity: 718  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 1  
Heavy Atom Count: 36  
Hydrogen Bond Acceptor Count: 8  
Hydrogen Bond Donor Count: 2  
Rotatable Bond Count: 10  
XLogP3: 5  
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