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124236-29-9,MFCD00026989
Catalog No.:AA009DQ0

124236-29-9 | N-Ethyl-o-crotonotoluidide

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5g
98%
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$13.00   $9.00
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25g
98%
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$29.00   $21.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA009DQ0
Chemical Name:
N-Ethyl-o-crotonotoluidide
CAS Number:
124236-29-9
Molecular Formula:
C13H17NO
Molecular Weight:
203.2802
MDL Number:
MFCD00026989
SMILES:
CC=CC(=O)N(c1ccccc1C)CC
Properties
Computed Properties
 
Complexity:
235  
Covalently-Bonded Unit Count:
1  
Defined Bond Stereocenter Count:
1  
Heavy Atom Count:
15  
Hydrogen Bond Acceptor Count:
1  
Rotatable Bond Count:
3  
XLogP3:
2.8  

Downstream Synthesis Route

[1]CurrentPatentAssignee:NOVARTISAG;Novartis(w/oSandoz)-DE933804,1948,C[DRP/DRBPOrg.Chem.][DRP/DRBPOrg.Chem.]

[1]CurrentPatentAssignee:GeigyA.G.-CH253472,1946,A

124236-29-9   
N-ethyl-N-(2-methylphenyl)butanamide 

[1]Imada,Yasushi;Iida,Hiroki;Naota,Takeshi[JournaloftheAmericanChemicalSociety,2005,vol.127,#42,p.14544-14545]

[2]Pieber,Bartholomaeus;Martinez,SabrinaTeixeira;Cantillo,David;Kappe,C.Oliver[AngewandteChemie-InternationalEdition,2013,vol.52,#39,p.10241-10244][Angew.Chem.,2013,p.10431-10434]

[3]Pieber,Bartholomäus;Glasnov,Toma;Kappe,C.Oliver[Chemistry-AEuropeanJournal,2015,vol.21,#11,p.4368-4376]

Literature

Title: Agonistic effects of diverse xenobiotics on the constitutive androstane receptor as detected in a recombinant yeast-cell assay.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20180201

Title: Photocatalytic decomposition of crotamiton over aqueous TiO(2) suspensions: determination of intermediates and the reaction pathway.

Journal: Chemosphere 20120901

Title: Anti pruritic effects of topical crotamiton, capsaicin, and a corticosteroid on pruritogen-induced scratching behavior.

Journal: Experimental dermatology 20120301

Title: Assessment of groundwater pollution in Tokyo using PPCPs as sewage markers.

Journal: Environmental science & technology 20120207

Title: [Treatment of rosacea].

Journal: Annales de dermatologie et de venereologie 20110901

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Mass balance analysis of triclosan, diethyltoluamide, crotamiton and carbamazepine in sewage treatment plants.

Journal: Water science and technology : a journal of the International Association on Water Pollution Research 20100101

Title: Hydrophilic anthropogenic markers for quantification of wastewater contamination in ground- and surface waters.

Journal: Environmental toxicology and chemistry 20091201

Title: [Infantile scabies].

Journal: Annales de dermatologie et de venereologie 20081201

Title: A human case of otoacariasis involving a histiostomatid mite (Acari: Histiostomatidae).

Journal: The American journal of tropical medicine and hygiene 20070501

Title: Scabies: a ubiquitous neglected skin disease.

Journal: The Lancet. Infectious diseases 20061201

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Scabies presenting with bullous pemphigoid-like lesions.

Journal: Dermatology online journal 20060127

Title: Percutaneous absorption of crotamiton in man following single and multiple dosing.

Journal: Cutaneous and ocular toxicology 20060101

Title: [Demodicidosis in humans as a current problem in dermatology].

Journal: Wiadomosci parazytologiczne 20050101

Title: Triple allergic contact sensitivities due to ferbinac, crotamiton and diisopropanolamine.

Journal: Contact dermatitis 20031101

Title: Concomitant allergic reaction to cetyl alcohol and crotamiton.

Journal: Contact dermatitis 20031101

Title: Allergic contact dermatitis due to crotamiton.

Journal: Contact dermatitis 20031001

Title: Oral ivermectin treatment in two cases of scabies: effective in crusted scabies induced by corticosteroid but ineffective in nail scabies.

Journal: The Journal of dermatology 20030501

Title: Scabies.

Journal: Clinical evidence 20020601

Title: Scabies incognito presenting as urticaria pigmentosa in an infant.

Journal: Pediatric dermatology 20020101

Title: Crotamiton and narrow-band UVB phototherapy: novel approaches to alleviate pruritus of breast carcinoma skin infiltration.

Journal: Journal of pain and symptom management 20011001

Title: Scabies.

Journal: Pediatrics in review 20010901

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Tags:124236-29-9 Molecular Formula|124236-29-9 MDL|124236-29-9 SMILES|124236-29-9 N-Ethyl-o-crotonotoluidide