Home Amines 1216720-69-2
1216720-69-2,MFCD04039788
Catalog No.:AA009DXW

1216720-69-2 | 7H-Pyrrolo[3,2-f]quinazoline-1,3-diaMine, N3-cyclopropyl-7-[[4-(1-Methylethyl)phenyl]Methyl]-, (Hydrochloride) (1

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$65.00   $45.00
- +
5mg
≥98%
in stock  
$173.00   $121.00
- +
10mg
≥98%
in stock  
$315.00   $220.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA009DXW
Chemical Name:
7H-Pyrrolo[3,2-f]quinazoline-1,3-diaMine, N3-cyclopropyl-7-[[4-(1-Methylethyl)phenyl]Methyl]-, (Hydrochloride) (1
CAS Number:
1216720-69-2
Molecular Formula:
C23H27Cl2N5
Molecular Weight:
444.4000
MDL Number:
MFCD04039788
SMILES:
CC(c1ccc(cc1)Cn1ccc2c1ccc1c2c(N)nc(n1)NC1CC1)C.Cl.Cl
Properties
Computed Properties
 
Complexity:
527  
Covalently-Bonded Unit Count:
3  
Heavy Atom Count:
30  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
5  

Literature

Title: Ahn HS, et al. Inhibition of cellular action of thrombin by N3-cyclopropyl-7-[-(1-methylethyl)phenylmethyl-7H-pyrrolo, 2-fquinazoline-1,3-diamine (SCH 79797), a nonpeptide thrombin receptor antagonist. Biochem Pharmacol. 2000 Nov 15;60(10):1425-34.

Title: Di Serio C, et al. Protease-activated receptor 1-selective antagonist SCH79797 inhibits cell proliferation and induces apoptosis by a protease-activated receptor 1-independent mechanism. Basic Clin Pharmacol Toxicol. 2007 Jul;101(1):63-9.

Title: Sokolova E, et al. A novel therapeutic target in various lung diseases: airway proteases and protease-activated receptors. Pharmacol Ther. 2007 Jul;115(1):70-83.

Title: Strande JL, et al. SCH 79797, a selective PAR1 antagonist, limits myocardial ischemia/reperfusion injury in rat hearts. Basic Res Cardiol. 2007 Jul;102(4):350-8.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Related Products of 1216720-69-2
Tags:1216720-69-2 Molecular Formula|1216720-69-2 MDL|1216720-69-2 SMILES|1216720-69-2 7H-Pyrrolo[3,2-f]quinazoline-1,3-diaMine, N3-cyclopropyl-7-[[4-(1-Methylethyl)phenyl]Methyl]-, (Hydrochloride) (1