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126550-86-5
Catalog No.:AA009HHI

126550-86-5 | ALPHA-D-GAL-[1->4]-BETA-D-GAL-[1->4]-BETA-D-GLC-1->O-SPHINGOSINE

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1mg
≥98%
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$956.00   $669.00
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  • Technical Information
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  • Technical Information
  • Properties
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Technical Information
Catalog Number:
AA009HHI
Chemical Name:
ALPHA-D-GAL-[1->4]-BETA-D-GAL-[1->4]-BETA-D-GLC-1->O-SPHINGOSINE
CAS Number:
126550-86-5
Molecular Formula:
C36H67NO17
Molecular Weight:
785.9137
SMILES:
CCCCCCCCCCCCC/C=C/[C@H]([C@H](CO[C@@H]1O[C@H](CO)[C@H]([C@@H]([C@H]1O)O)O[C@@H]1O[C@H](CO)[C@@H]([C@@H]([C@H]1O)O)O[C@H]1O[C@H](CO)[C@@H]([C@@H]([C@H]1O)O)O)N)O
Properties
Computed Properties
 
Complexity:
1030  
Covalently-Bonded Unit Count:
1  
Defined Bond Stereocenter Count:
1  
Heavy Atom Count:
54  
Hydrogen Bond Acceptor Count:
18  
Hydrogen Bond Donor Count:
12  
Rotatable Bond Count:
24  
Undefined Atom Stereocenter Count:
17  
XLogP3:
-0.6  

Literature

Title: Urinary globotriaosylsphingosine-related biomarkers for Fabry disease targeted by metabolomics.

Journal: Analytical chemistry 20120320

Title: Quantification of the Fabry marker lysoGb3 in human plasma by tandem mass spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120201

Title: Long-term effect of antibodies against infused alpha-galactosidase A in Fabry disease on plasma and urinary (lyso)Gb3 reduction and treatment outcome.

Journal: PloS one 20120101

Title: Globotriaosylsphingosine actions on human glomerular podocytes: implications for Fabry nephropathy.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20110601

Title: Consequences of a global enzyme shortage of agalsidase beta in adult Dutch Fabry patients.

Journal: Orphanet journal of rare diseases 20110101

Title: How well does urinary lyso-Gb3 function as a biomarker in Fabry disease?

Journal: Clinica chimica acta; international journal of clinical chemistry 20101214

Title: Tissue and plasma globotriaosylsphingosine could be a biomarker for assessing enzyme replacement therapy for Fabry disease.

Journal: Biochemical and biophysical research communications 20100903

Title: Plasma globotriaosylsphingosine: diagnostic value and relation to clinical manifestations of Fabry disease.

Journal: Biochimica et biophysica acta 20100901

Title: Plasma globotriaosylsphingosine as a biomarker of Fabry disease.

Journal: Molecular genetics and metabolism 20100701

Title: Binding of Silurus asotus lectin to Gb3 on Raji cells causes disappearance of membrane-bound form of HSP70.

Journal: Biochimica et biophysica acta 20090201

Title: Synthesis and properties of a mitochondrial peripheral benzodiazepine receptor conjugate.

Journal: ChemMedChem 20081101

Title: Tumor-specific Hsp70 plasma membrane localization is enabled by the glycosphingolipid Gb3.

Journal: PloS one 20080101

Title: Induction of cytokines by toxins that have an identical RNA N-glycosidase activity: Shiga toxin, ricin, and modeccin.

Journal: Biochimica et biophysica acta 20040317

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Tags:126550-86-5 Molecular Formula|126550-86-5 MDL|126550-86-5 SMILES|126550-86-5 ALPHA-D-GAL-[1->4]-BETA-D-GAL-[1->4]-BETA-D-GLC-1->O-SPHINGOSINE