[1]CurrentPatentAssignee:C.H.BoehringerSohnAG&Co.KG-US2002/198380,2002,A1
Title: Identification of potent Yes1 kinase inhibitors using a library screening approach.
Journal: Bioorganic & medicinal chemistry letters 20130801
Title: Characterization of aldehyde oxidase enzyme activity in cryopreserved human hepatocytes.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20120201
Title: Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Journal: PLoS computational biology 20111201
Title: Epidermal growth factor receptor inhibitors for radiotherapy: biological rationale and preclinical results.
Journal: The Journal of pharmacy and pharmacology 20080801
Title: A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
Journal: Proceedings of the National Academy of Sciences of the United States of America 20071218
Title: EGFR-TK inhibition before radiotherapy reduces tumour volume but does not improve local control: differential response of cancer stem cells and nontumourigenic cells?
Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20070601
Title: Antiproliferative effects of EGFR tyrosine kinase inhibition and radiation-induced genotoxic injury are attenuated by adhesion to fibronectin.
Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20060801
Title: Blockage of epidermal growth factor receptor-phosphatidylinositol 3-kinase-AKT signaling increases radiosensitivity of K-RAS mutated human tumor cells in vitro by affecting DNA repair.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20060701
Title: Different classes of EGFR inhibitors may have different potential to improve local tumour control after fractionated irradiation: a study on C225 in FaDu hSCC.
Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20050201
Title: Radiosensitization of Ras-mutated human tumor cells in vitro by the specific EGF receptor antagonist BIBX1382BS.
Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20050201
Title: Inhibition of epidermal growth factor receptor activity by two pyrimidopyrimidine derivatives.
Journal: The Journal of pharmacology and experimental therapeutics 20041101
Title: Caenorhabditis elegans as model system for rapid toxicity assessment of pharmaceutical compounds.
Journal: Journal of pharmacological and toxicological methods 20040101
Title: Selective inhibition of the epidermal growth factor receptor tyrosine kinase by BIBX1382BS and the improvement of growth delay, but not local control, after fractionated irradiation in human FaDu squamous cell carcinoma in the nude mouse.
Journal: International journal of radiation biology 20030701
Title: Phase I and pharmacokinetic study of BIBX 1382 BS, an epidermal growth factor receptor (EGFR) inhibitor, given in a continuous daily oral administration.
Journal: European journal of cancer (Oxford, England : 1990) 20020501
Title: BIBX1382BS, but not AG1478 or PD153035, inhibits the ErbB kinases at different concentrations in intact cells.
Journal: Biochemical and biophysical research communications 20010216
Title: Dittrich Ch, et al. Phase I and pharmacokinetic study of BIBX 1382 BS, an epidermal growth factor receptor (EGFR) inhibitor, given in a continuous daily oral administration. Eur J Cancer. 2002 May;38(8):1072-80.
Title: Solca FF, et al. Inhibition of epidermal growth factor receptor activity by two pyrimidopyrimidine derivatives. J Pharmacol Exp Ther. 2004 Nov;311(2):502-9.
