Home Other Building Blocks 1531634-31-7
1531634-31-7,MFCD28160694
Catalog No.:AA00ABK2

1531634-31-7 | AF38469

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$96.00   $67.00
- +
5mg
≥98%
in stock  
$428.00   $299.00
- +
10mg
≥98%
in stock  
$759.00   $531.00
- +
25mg
≥98%
in stock  
$1,420.00   $994.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00ABK2
Chemical Name:
AF38469
CAS Number:
1531634-31-7
Molecular Formula:
C15H11F3N2O3
Molecular Weight:
324.2546
MDL Number:
MFCD28160694
SMILES:
Cc1cccc(n1)NC(=O)c1ccc(cc1C(=O)O)C(F)(F)F
Properties
Computed Properties
 
Complexity:
456  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
23  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
3  
XLogP3:
2.8  

Downstream Synthesis Route

[1]Schroder,TennaJuul;Christensen,Soren;Lindberg,Samsa;Langgard,Morten;David,Laurent;Maltas,PhilipJ.;Eskildsen,Jorgen;Jacobsen,Jan;Tagmose,Lena;Simonsen,KlausBaek;BiilmannRonn,LarsChristian;DeJong,IngeE.M.;Malik,IbrahimJ.;Karlsson,Jens-Jakob;Bundgaard,Christoffer;Egebjerg,Jan;Stavenhagen,JeffreyB.;Strandbygard,Dorthe;Thirup,Soren;Andersen,JacobLauwring;Uppalanchi,Srinivas;Pervaram,Sridhar;Kasturi,ShivaPrasad;Eradi,Pradheep;Sakumudi,DurgaRao;Watson,StephenP.[BioorganicandMedicinalChemistryLetters,2014,vol.24,#1,p.177-180]

[2]CurrentPatentAssignee:H.LUNDBECKA/S-WO2014/114779,2014,A1

[1]CurrentPatentAssignee:H.LUNDBECKA/S-WO2014/114779,2014,A1Locationinpatent:Page/Pagecolumn54

[2]Schroder,TennaJuul;Christensen,Soren;Lindberg,Samsa;Langgard,Morten;David,Laurent;Maltas,PhilipJ.;Eskildsen,Jorgen;Jacobsen,Jan;Tagmose,Lena;Simonsen,KlausBaek;BiilmannRonn,LarsChristian;DeJong,IngeE.M.;Malik,IbrahimJ.;Karlsson,Jens-Jakob;Bundgaard,Christoffer;Egebjerg,Jan;Stavenhagen,JeffreyB.;Strandbygard,Dorthe;Thirup,Soren;Andersen,JacobLauwring;Uppalanchi,Srinivas;Pervaram,Sridhar;Kasturi,ShivaPrasad;Eradi,Pradheep;Sakumudi,DurgaRao;Watson,StephenP.[BioorganicandMedicinalChemistryLetters,2014,vol.24,#1,p.177-180]

Literature

Title: Schroder TJ, et al. The identification of AF38469: an orally bioavailable inhibitor of the VPS10P family sorting receptor Sortilin. Bioorg Med Chem Lett. 2014 Jan 1;24(1):177-80.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Related Products of 1531634-31-7
Tags:1531634-31-7 Molecular Formula|1531634-31-7 MDL|1531634-31-7 SMILES|1531634-31-7 AF38469