1562338-42-4
[1]CurrentPatentAssignee:Novartis(w/oSandoz);NOVARTISAG-WO2014/28459,2014,A1Locationinpatent:Page/Pagecolumn185
[1]CurrentPatentAssignee:Novartis(w/oSandoz);NOVARTISAG-WO2014/28459,2014,A1Locationinpatent:Page/Pagecolumn185;186
[1]JournalofMedicinalChemistry,2018,vol.61,p.11021-11036
[1]Cheung,AtwoodK.;Hurley,Brian;Kerrigan,Ryan;Shu,Lei;Chin,DonovanN.;Shen,Yiping;O'Brien,Gary;Sung,MooJe;Hou,Ying;Axford,Jake;Cody,Emma;Sun,Robert;Fazal,Aleem;Fridrich,Cary;Sanchez,CarinaC.;Tomlinson,RonaldC.;Jain,Monish;Deng,Lin;Hoffmaster,Keith;Song,Cheng;VanHoosear,Mailin;Shin,Youngah;Servais,Rebecca;Towler,Christopher;Hild,Marc;Curtis,Daniel;Dietrich,WilliamF.;Hamann,LawrenceG.;Briner,Karin;Chen,KarenS.;Kobayashi,Dione;Sivasankaran,Rajeev;Dales,NatalieA.[JournalofMedicinalChemistry,2018,vol.61,#24,p.11021-11036]
[1]Cheung,AtwoodK.;Hurley,Brian;Kerrigan,Ryan;Shu,Lei;Chin,DonovanN.;Shen,Yiping;O'Brien,Gary;Sung,MooJe;Hou,Ying;Axford,Jake;Cody,Emma;Sun,Robert;Fazal,Aleem;Fridrich,Cary;Sanchez,CarinaC.;Tomlinson,RonaldC.;Jain,Monish;Deng,Lin;Hoffmaster,Keith;Song,Cheng;VanHoosear,Mailin;Shin,Youngah;Servais,Rebecca;Towler,Christopher;Hild,Marc;Curtis,Daniel;Dietrich,WilliamF.;Hamann,LawrenceG.;Briner,Karin;Chen,KarenS.;Kobayashi,Dione;Sivasankaran,Rajeev;Dales,NatalieA.[JournalofMedicinalChemistry,2018,vol.61,#24,p.11021-11036]
Title: Palacino J, et al. SMN2 splice modulators enhance U1-pre-mRNA association and rescue SMA mice. Nat Chem Biol. 2015 Jul;11(7):511-517.
Title: Cheung AK, et al. Discovery of Small Molecule Splicing Modulators of Survival Motor Neuron-2 (SMN2) for the Treatment of Spinal Muscular Atrophy (SMA). J Med Chem. 2018 Dec 27;61(24):11021-11036.
