146204-42-4,MFCD30489752
Catalog No.:AA00ABP6

146204-42-4 | BM 212

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$46.00   $32.00
- +
5mg
≥98%
in stock  
$199.00   $139.00
- +
10mg
≥98%
in stock  
$373.00   $261.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA00ABP6
Chemical Name:
BM 212
CAS Number:
146204-42-4
Molecular Formula:
C23H25Cl2N3
Molecular Weight:
414.3707
MDL Number:
MFCD30489752
SMILES:
CN1CCN(CC1)Cc1cc(n(c1C)c1ccc(cc1)Cl)c1ccc(cc1)Cl
Properties
Computed Properties
 
Complexity:
480  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
28  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
0  
Isotope Atom Count:
0  
Rotatable Bond Count:
4  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
5.3  

Literature

Title: Discovery of new leads against Mycobacterium tuberculosis using scaffold hopping and shape based similarity.

Journal: Bioorganic & medicinal chemistry 20170901

Title: Discovery of a small-molecule antiviral targeting the HIV-1 matrix protein.

Journal: Bioorganic & medicinal chemistry letters 20130215

Title: Improved BM212 MmpL3 inhibitor analogue shows efficacy in acute murine model of tuberculosis infection.

Journal: PloS one 20130101

Title: 1,5-Diaryl-2-ethyl pyrrole derivatives as antimycobacterial agents: design, synthesis, and microbiological evaluation.

Journal: European journal of medicinal chemistry 20091101

Title: 1,5-Diphenylpyrrole derivatives as antimycobacterial agents. Probing the influence on antimycobacterial activity of lipophilic substituents at the phenyl rings.

Journal: Journal of medicinal chemistry 20080626

Title: New derivatives of BM212: A class of antimycobacterial compounds based on the pyrrole ring as a scaffold.

Journal: Mini reviews in medicinal chemistry 20070101

Title: Antimycobacterial agents. Novel diarylpyrrole derivatives of BM212 endowed with high activity toward Mycobacterium tuberculosis and low cytotoxicity.

Journal: Journal of medicinal chemistry 20060810

Title: New small-molecule synthetic antimycobacterials.

Journal: Antimicrobial agents and chemotherapy 20050601

Title: Antimycobacterial compounds. Optimization of the BM 212 structure, the lead compound for a new pyrrole derivative class.

Journal: Bioorganic & medicinal chemistry 20050215

Title: Antimycobacterial compounds. New pyrrole derivatives of BM212.

Journal: Bioorganic & medicinal chemistry 20040315

Title: Importance of the thiomorpholine introduction in new pyrrole derivatives as antimycobacterial agents analogues of BM 212.

Journal: Bioorganic & medicinal chemistry 20030220

Title: BM 212 and its derivatives as a new class of antimycobacterial active agents.

Journal: Current medicinal chemistry 20021101

Title: New pyrrole derivatives as antimycobacterial agents analogs of BM212.

Journal: Bioorganic & medicinal chemistry letters 19991018

Title: Bactericidal activities of the pyrrole derivative BM212 against multidrug-resistant and intramacrophagic Mycobacterium tuberculosis strains.

Journal: Antimicrobial agents and chemotherapy 19981101

Title: Deidda D et al. Bactericidal activities of the pyrrole derivative BM212 against multidrug-resistant and intramacrophagic Mycobacterium tuberculosis strains. Antimicrob Agents Chemother. 1998 Nov;42(11):3035-7.

Title: Poce G et al. Improved BM212 MmpL3 inhibitor analogue shows efficacy in acute murine model of tuberculosis infection. PLoS One. 2013;8(2)

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Tags:146204-42-4 Molecular Formula|146204-42-4 MDL|146204-42-4 SMILES|146204-42-4 BM 212
Catalog No.: AA00ABP6
146204-42-4,MFCD30489752
146204-42-4 | BM 212
Pack Size: 1mg
Purity: ≥98%
in stock
$46.00 $32.00
Pack Size: 5mg
Purity: ≥98%
in stock
$199.00 $139.00
Pack Size: 10mg
Purity: ≥98%
in stock
$373.00 $261.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA00ABP6
Chemical Name: BM 212
CAS Number: 146204-42-4
Molecular Formula: C23H25Cl2N3
Molecular Weight: 414.3707
MDL Number: MFCD30489752
SMILES: CN1CCN(CC1)Cc1cc(n(c1C)c1ccc(cc1)Cl)c1ccc(cc1)Cl
Properties
Complexity: 480  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 28  
Hydrogen Bond Acceptor Count: 2  
Hydrogen Bond Donor Count: 0  
Isotope Atom Count: 0  
Rotatable Bond Count: 4  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: 5.3  
Literature fold

Title: Discovery of new leads against Mycobacterium tuberculosis using scaffold hopping and shape based similarity.

Journal: Bioorganic & medicinal chemistry20170901

Title: Discovery of a small-molecule antiviral targeting the HIV-1 matrix protein.

Journal: Bioorganic & medicinal chemistry letters20130215

Title: Improved BM212 MmpL3 inhibitor analogue shows efficacy in acute murine model of tuberculosis infection.

Journal: PloS one20130101

Title: 1,5-Diaryl-2-ethyl pyrrole derivatives as antimycobacterial agents: design, synthesis, and microbiological evaluation.

Journal: European journal of medicinal chemistry20091101

Title: 1,5-Diphenylpyrrole derivatives as antimycobacterial agents. Probing the influence on antimycobacterial activity of lipophilic substituents at the phenyl rings.

Journal: Journal of medicinal chemistry20080626

Title: New derivatives of BM212: A class of antimycobacterial compounds based on the pyrrole ring as a scaffold.

Journal: Mini reviews in medicinal chemistry20070101

Title: Antimycobacterial agents. Novel diarylpyrrole derivatives of BM212 endowed with high activity toward Mycobacterium tuberculosis and low cytotoxicity.

Journal: Journal of medicinal chemistry20060810

Title: New small-molecule synthetic antimycobacterials.

Journal: Antimicrobial agents and chemotherapy20050601

Title: Antimycobacterial compounds. Optimization of the BM 212 structure, the lead compound for a new pyrrole derivative class.

Journal: Bioorganic & medicinal chemistry20050215

Title: Antimycobacterial compounds. New pyrrole derivatives of BM212.

Journal: Bioorganic & medicinal chemistry20040315

Title: Importance of the thiomorpholine introduction in new pyrrole derivatives as antimycobacterial agents analogues of BM 212.

Journal: Bioorganic & medicinal chemistry20030220

Title: BM 212 and its derivatives as a new class of antimycobacterial active agents.

Journal: Current medicinal chemistry20021101

Title: New pyrrole derivatives as antimycobacterial agents analogs of BM212.

Journal: Bioorganic & medicinal chemistry letters19991018

Title: Bactericidal activities of the pyrrole derivative BM212 against multidrug-resistant and intramacrophagic Mycobacterium tuberculosis strains.

Journal: Antimicrobial agents and chemotherapy19981101

Title: Deidda D et al. Bactericidal activities of the pyrrole derivative BM212 against multidrug-resistant and intramacrophagic Mycobacterium tuberculosis strains. Antimicrob Agents Chemother. 1998 Nov;42(11):3035-7.

Title: Poce G et al. Improved BM212 MmpL3 inhibitor analogue shows efficacy in acute murine model of tuberculosis infection. PLoS One. 2013;8(2)

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