Name: Name:GNE-140 (racemate)
Brand: AABLOCKS
SKU: AA00ABPD
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA00ABPD

Chemical Name: GNE-140 (racemate)

CAS Number: 1802977-61-2

Molecular Formula: C25H23ClN2O3S2

Molecular Weight: 499.0447

MDL Number: MFCD30489754

SMILES: O=C1CC(NC(=O)C1Sc1ccccc1Cl)(c1ccsc1)c1ccc(cc1)N1CCOCC1

Properties

Complexity: 714

Covalently-Bonded Unit Count: 1

Heavy Atom Count: 33

Hydrogen Bond Acceptor Count: 6

Hydrogen Bond Donor Count: 1

Rotatable Bond Count: 5

Undefined Atom Stereocenter Count: 2

XLogP3: 4.6

Downstream Synthesis Route

1802977-61-2

2251749-45-6

2251749-46-7

[1]Purkey,HansE.;Robarge,Kirk;Chen,Jinhua;Chen,Zhongguo;Corson,LauraB.;Ding,CharlesZ.;Dipasquale,AntonioG.;Dragovich,PeterS.;Eigenbrot,Charles;Evangelista,Marie;Fauber,BenjaminP.;Gao,Zhenting;Ge,Hongxiu;Hitz,Anna;Ho,Qunh;Labadie,SharadaS.;Lai,KwongWah;Liu,Wenfeng;Liu,Yajing;Li,Chiho;Ma,Shuguang;Malek,Shiva;O'Brien,Thomas;Pang,Jodie;Peterson,David;Salphati,Laurent;Sideris,Steve;Ultsch,Mark;Wei,Binqing;Yen,Ivana;Yue,Qin;Zhang,Huihui;Zhou,Aihe[ACSMedicinalChemistryLetters,2016,vol.7,#10,p.896-901]

[2]CurrentPatentAssignee:ARCTICPHARMA-WO2018/211278,2018,A1Locationinpatent:Page/Pagecolumn54

[3]CurrentPatentAssignee:ARCTICPHARMA-WO2018/211277,2018,A1Locationinpatent:Page/Pagecolumn74

1802977-61-2

CASUnavailable

[1]Purkey,HansE.;Robarge,Kirk;Chen,Jinhua;Chen,Zhongguo;Corson,LauraB.;Ding,CharlesZ.;Dipasquale,AntonioG.;Dragovich,PeterS.;Eigenbrot,Charles;Evangelista,Marie;Fauber,BenjaminP.;Gao,Zhenting;Ge,Hongxiu;Hitz,Anna;Ho,Qunh;Labadie,SharadaS.;Lai,KwongWah;Liu,Wenfeng;Liu,Yajing;Li,Chiho;Ma,Shuguang;Malek,Shiva;O'Brien,Thomas;Pang,Jodie;Peterson,David;Salphati,Laurent;Sideris,Steve;Ultsch,Mark;Wei,Binqing;Yen,Ivana;Yue,Qin;Zhang,Huihui;Zhou,Aihe[ACSMedicinalChemistryLetters,2016,vol.7,#10,p.896-901]

110-91-8

1809796-29-9

1802977-61-2

[1]Purkey,HansE.;Robarge,Kirk;Chen,Jinhua;Chen,Zhongguo;Corson,LauraB.;Ding,CharlesZ.;Dipasquale,AntonioG.;Dragovich,PeterS.;Eigenbrot,Charles;Evangelista,Marie;Fauber,BenjaminP.;Gao,Zhenting;Ge,Hongxiu;Hitz,Anna;Ho,Qunh;Labadie,SharadaS.;Lai,KwongWah;Liu,Wenfeng;Liu,Yajing;Li,Chiho;Ma,Shuguang;Malek,Shiva;O'Brien,Thomas;Pang,Jodie;Peterson,David;Salphati,Laurent;Sideris,Steve;Ultsch,Mark;Wei,Binqing;Yen,Ivana;Yue,Qin;Zhang,Huihui;Zhou,Aihe[ACSMedicinalChemistryLetters,2016,vol.7,#10,p.896-901]

1122-91-4

1802977-61-2

[1]Purkey,HansE.;Robarge,Kirk;Chen,Jinhua;Chen,Zhongguo;Corson,LauraB.;Ding,CharlesZ.;Dipasquale,AntonioG.;Dragovich,PeterS.;Eigenbrot,Charles;Evangelista,Marie;Fauber,BenjaminP.;Gao,Zhenting;Ge,Hongxiu;Hitz,Anna;Ho,Qunh;Labadie,SharadaS.;Lai,KwongWah;Liu,Wenfeng;Liu,Yajing;Li,Chiho;Ma,Shuguang;Malek,Shiva;O'Brien,Thomas;Pang,Jodie;Peterson,David;Salphati,Laurent;Sideris,Steve;Ultsch,Mark;Wei,Binqing;Yen,Ivana;Yue,Qin;Zhang,Huihui;Zhou,Aihe[ACSMedicinalChemistryLetters,2016,vol.7,#10,p.896-901]

1802977-61-2 | GNE-140 (racemate)