Home Other Building Blocks 1454585-06-8
1454585-06-8,MFCD30187527
Catalog No.:AA00ABQI

1454585-06-8 | Sr-3029

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Purity
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Price(USD)
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5mg
≥98%
in stock  
$123.00   $86.00
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10mg
≥98%
in stock  
$230.00   $161.00
- +
25mg
98%
in stock  
$307.00   $215.00
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100mg
98%
in stock  
$743.00   $520.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00ABQI
Chemical Name:
Sr-3029
CAS Number:
1454585-06-8
Molecular Formula:
C23H19F3N8O
Molecular Weight:
480.4452
MDL Number:
MFCD30187527
SMILES:
Fc1cccc(c1)n1cnc2c1nc(nc2NCc1[nH]c2c(n1)ccc(c2F)F)N1CCOCC1
Properties
Computed Properties
 
Complexity:
720  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
35  
Hydrogen Bond Acceptor Count:
10  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
5  
XLogP3:
3.5  

Downstream Synthesis Route

[1]Bibian,Mathieu;Rahaim,RonaldJ.;Choi,JunYong;Noguchi,Yoshihiko;Schürer,Stephan;Chen,Weimin;Nakanishi,Shima;Licht,Konstantin;Rosenberg,LauraH.;Li,Lin;Feng,Yangbo;Cameron,MichaelD.;Duckett,DerekR.;Cleveland,JohnL.;Roush,WilliamR.[BioorganicandMedicinalChemistryLetters,2013,vol.23,#15,p.4374-4380]

[2]CurrentPatentAssignee:STATEUNIVERSITYSYSTEMOFFLORIDA-WO2013/130461,2013,A1

[3]Monastyrskyi,Andrii;Nilchan,Napon;Quereda,Victor;Noguchi,Yoshihiko;Ruiz,Claudia;Grant,Wayne;Cameron,Michael;Duckett,Derek;Roush,William[BioorganicandMedicinalChemistry,2018,vol.26,#3,p.590-602]

Literature

Title: Distribution and removal of added mercury in milk.

Journal: Journal of dairy science 19751201

Title: Bibian M, et al. Development of highly selective casein kinase 1δ/1ε (CK1δ/ε) inhibitors with potent antiproliferative properties. Bioorg Med Chem Lett. 2013 Aug 1;23(15):4374-80.

Title: Rosenberg LH, et al. Therapeutic targeting of casein kinase 1δ in breast cancer. Sci Transl Med. 2015 Dec 16;7(318):318ra202.

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SDS
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Tags:1454585-06-8 Molecular Formula|1454585-06-8 MDL|1454585-06-8 SMILES|1454585-06-8 Sr-3029