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191102-79-1,MFCD02683592
Catalog No.:AA00ADE5

191102-79-1 | GGTI 2133

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
95%
1 week  
$392.00   $275.00
- +
5mg
95%
1 week  
$883.00   $618.00
- +
10mg
95%
1 week  
$1,186.00   $830.00
- +
25mg
95%
1 week  
$1,760.00   $1,232.00
- +
50mg
95%
1 week  
$2,320.00   $1,624.00
- +
100mg
95%
1 week  
$3,212.00   $2,248.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00ADE5
Chemical Name:
GGTI 2133
CAS Number:
191102-79-1
Molecular Formula:
C27H28N4O3
Molecular Weight:
456.5362
MDL Number:
MFCD02683592
SMILES:
CC(C[C@@H](C(=O)O)NC(=O)c1ccc(cc1c1cccc2c1cccc2)NCc1c[nH]cn1)C
Properties
Computed Properties
 
Complexity:
687  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
34  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
9  
XLogP3:
5  

Literature

Title: Inhibition of prenyltransferase activity by statins in both liver and muscle cell lines is not causative of cytotoxicity.

Journal: Toxicology 20150302

Title: Protein prenylation contributes to the effects of LPS on EFS-induced responses in human isolated bronchi.

Journal: American journal of respiratory cell and molecular biology 20111001

Title: Simvastatin inhibits induction of matrix metalloproteinase-9 in rat alveolar macrophages exposed to cigarette smoke extract.

Journal: Experimental & molecular medicine 20090430

Title: GGTI-2133, an inhibitor of geranylgeranyltransferase, inhibits infiltration of inflammatory cells into airways in mouse experimental asthma.

Journal: International journal of immunopathology and pharmacology 20090101

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SDS
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