Title: Regulated endocrine-specific protein 18 (RESP18) is localized to and regulated in A-like cells and G-cells in rat stomach.
Journal: Regulatory peptides 20120820
Title: Single oral doses of netazepide (YF476), a gastrin receptor antagonist, cause dose-dependent, sustained increases in gastric pH compared with placebo and ranitidine in healthy subjects.
Journal: Alimentary pharmacology & therapeutics 20120701
Title: JNJ-26070109 [(R)4-bromo-N-[1-(2,4-difluoro-phenyl)-ethyl]-2-(quinoxaline-5-sulfonylamino)-benzamide]: a novel, potent, and selective cholecystokinin 2 receptor antagonist with good oral bioavailability.
Journal: The Journal of pharmacology and experimental therapeutics 20110701
Title: The CCK(2) receptor antagonist, YF476, inhibits Mastomys ECL cell hyperplasia and gastric carcinoid tumor development.
Journal: Regulatory peptides 20100608
Title: Reflections on some pilot trials of gastrin receptor blockade in pancreatic cancer.
Journal: European journal of cancer (Oxford, England : 1990) 20090201
Title: Achiral, selective CCK2 receptor antagonists based on a 1,3,5-benzotriazepine-2,4-dione template.
Journal: Bioorganic & medicinal chemistry 20080315
Title: A comparison of the effects of gastrin, somatostatin and dopamine receptor ligands on rat gastric enterochromaffin-like cell secretion and proliferation.
Journal: Regulatory peptides 20071004
Title: Optimization of 1,3,4-benzotriazepine-based CCK(2) antagonists to obtain potent, orally active inhibitors of gastrin-mediated gastric acid secretion.
Journal: Journal of medicinal chemistry 20070628
Title: Gastrin regulates the TFF2 promoter through gastrin-responsive cis-acting elements and multiple signaling pathways.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20070601
Title: Novel, achiral 1,3,4-benzotriazepine analogues of 1,4-benzodiazepine-based CCK(2) antagonists that display high selectivity over CCK(1) receptors.
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Title: Gastrin increases murine intestinal crypt regeneration following injury.
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Title: Synergistic inhibitory effects of gastrin and histamine receptor antagonists on Helicobacter-induced gastric cancer.
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Title: Secretory organelles in ECL cells: effects of pharmacological blockade of the gastrin/CCK2 receptor versus its elimination by gene targeting.
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Title: CCK-B receptor antagonist YF476 inhibits pancreatic enzyme secretion at a duodenal level in pigs.
Journal: Scandinavian journal of gastroenterology 20040901
Title: Validation of a liquid chromatographic-tandem mass spectrometric method for the measurement of (R)-1-[2,3-dihydro-2-oxo-1-pivaloylmethyl-5-(2-pyridyl)-1H-1,4-benzodiazepin-3-yl]-3-(3-methylaminophenyl)urea (YF476) in human plasma.
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Title: Pharmacological analysis of CCK(2) receptor ligands using COS-7 and SK-N-MC cells, expressing the human CCK(2) receptor.
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Title: Gastric acid secretion in L-histidine decarboxylase-deficient mice.
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Title: Effects of CCK2 receptor blockade on growth parameters in gastrointestinal tract and pancreas in rats.
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Title: Mobilization of rat stomach ECL-cell histamine in response to short- or long-term treatment with omeprazole and/or YF 476 studied by gastric submucosal microdialysis in conscious rats.
Journal: British journal of pharmacology 20010501
Title: Carbon-11 labelled cholecystokininB antagonists: radiosynthesis and evaluation in rats.
Journal: Life sciences 20010202
Title: YF476 is a new potent and selective gastrin/cholecystokinin-B receptor antagonist in vitro and in vivo.
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Title: (3R)-N-(1-(tert-butylcarbonylmethyl)-2,3-dihydro-2-oxo-5-(2-pyridyl)-1H-1,4-benzodiazepin-3-yl)-N'-(3-(methylamino)phenyl)urea (YF476): a potent and orally active gastrin/CCK-B antagonist.
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