184162-64-9,MFCD03106493
Catalog No.:AA00AKNX

184162-64-9 | 2-[[[5-(2,6-DIMETHOXYPHENYL)-1-[4-[[[3-(DIMETHYLAMINO)PROPYL]METHYLAMINO]CARBONYL]-2-(1-METHYLETHYL)PHENYL]-1H-PYRAZOL-3-YL]CARBONYL]AMINO]-TRICYCLO[3.3.1.13,7]DECANE-2-CARBOXYLIC ACID

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥97%(HPLC)
in stock  
$297.00   $208.00
- +
5mg
98%
in stock  
$333.00   $233.00
- +
10mg
≥97%(HPLC)
in stock  
$565.00   $395.00
- +
25mg
98%
in stock  
$1,158.00   $810.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA00AKNX
Chemical Name:
2-[[[5-(2,6-DIMETHOXYPHENYL)-1-[4-[[[3-(DIMETHYLAMINO)PROPYL]METHYLAMINO]CARBONYL]-2-(1-METHYLETHYL)PHENYL]-1H-PYRAZOL-3-YL]CARBONYL]AMINO]-TRICYCLO[3.3.1.13,7]DECANE-2-CARBOXYLIC ACID
CAS Number:
184162-64-9
Molecular Formula:
C39H51N5O6
Molecular Weight:
685.8521
MDL Number:
MFCD03106493
SMILES:
COc1cccc(c1c1cc(nn1c1ccc(cc1C(C)C)C(=O)N(CCCN(C)C)C)C(=O)N[C@]1(C(=O)O)[C@@H]2C[C@@H]3C[C@H]1C[C@H](C2)C3)OC
Properties
Computed Properties
 
Complexity:
1170  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
50  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
13  
XLogP3:
3.6  

Literature

Title: Cardio-respiratory effects of systemic neurotensin injection are mediated through activation of neurotensin NTS₁ receptors.

Journal: European journal of pharmacology 20120915

Title: Different interactions of prolyl oligopeptidase and neurotensin in dopaminergic function of the rat nigrostriatal and mesolimbic pathways.

Journal: Neurochemical research 20120901

Title: The neurotensin receptor-1 promotes tumor development in a sporadic but not an inflammation-associated mouse model of colon cancer.

Journal: International journal of cancer 20120415

Title: Neurotensin signaling induces intracellular alkalinization and interleukin-8 expression in human pancreatic cancer cells.

Journal: Molecular oncology 20090601

Title: Endogenous neurotensin is involved in estrous cycle related alterations in prepulse inhibition of the acoustic startle reflex in female rats.

Journal: Psychoneuroendocrinology 20080201

Title: Neurotensin reduces glutamatergic transmission in the dorsolateral striatum via retrograde endocannabinoid signaling.

Journal: Neuropharmacology 20080101

Title: Neurotensin antagonist acutely and robustly attenuates locomotion that accompanies stimulation of a neurotensin-containing pathway from rostrobasal forebrain to the ventral tegmental area.

Journal: The European journal of neuroscience 20060701

Title: Regulation of DARPP-32 Thr75 phosphorylation by neurotensin in neostriatal neurons: involvement of glutamate signalling.

Journal: The European journal of neuroscience 20030901

Title: Neurotensin regulates DARPP-32 thr34 phosphorylation in neostriatal neurons by activation of dopamine D1-type receptors.

Journal: Journal of neurochemistry 20020401

Title: Neurotensin induces mating in Saccharomyces cerevisiae cells that express human neurotensin receptor type 1 in place of the endogenous pheromone receptor.

Journal: European journal of biochemistry 20010901

Title: Enhanced neurotensin neurotransmission is involved in the clinically relevant behavioral effects of antipsychotic drugs: evidence from animal models of sensorimotor gating.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20010115

Title: Biochemical and pharmacological activities of SR 142948A, a new potent neurotensin receptor antagonist.

Journal: The Journal of pharmacology and experimental therapeutics 19970201

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Related Products of 184162-64-9
Tags:184162-64-9 Molecular Formula|184162-64-9 MDL|184162-64-9 SMILES|184162-64-9 2-[[[5-(2,6-DIMETHOXYPHENYL)-1-[4-[[[3-(DIMETHYLAMINO)PROPYL]METHYLAMINO]CARBONYL]-2-(1-METHYLETHYL)PHENYL]-1H-PYRAZOL-3-YL]CARBONYL]AMINO]-TRICYCLO[3.3.1.13,7]DECANE-2-CARBOXYLIC ACID
Catalog No.: AA00AKNX
184162-64-9,MFCD03106493
184162-64-9 | 2-[[[5-(2,6-DIMETHOXYPHENYL)-1-[4-[[[3-(DIMETHYLAMINO)PROPYL]METHYLAMINO]CARBONYL]-2-(1-METHYLETHYL)PHENYL]-1H-PYRAZOL-3-YL]CARBONYL]AMINO]-TRICYCLO[3.3.1.13,7]DECANE-2-CARBOXYLIC ACID
Pack Size: 1mg
Purity: ≥97%(HPLC)
in stock
$297.00 $208.00
Pack Size: 5mg
Purity: 98%
in stock
$333.00 $233.00
Pack Size: 10mg
Purity: ≥97%(HPLC)
in stock
$565.00 $395.00
Pack Size: 25mg
Purity: 98%
in stock
$1,158.00 $810.00
Quantity
- +
Add to Card
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bulk Quotation Request
Technical Information
Catalog Number: AA00AKNX
Chemical Name: 2-[[[5-(2,6-DIMETHOXYPHENYL)-1-[4-[[[3-(DIMETHYLAMINO)PROPYL]METHYLAMINO]CARBONYL]-2-(1-METHYLETHYL)PHENYL]-1H-PYRAZOL-3-YL]CARBONYL]AMINO]-TRICYCLO[3.3.1.13,7]DECANE-2-CARBOXYLIC ACID
CAS Number: 184162-64-9
Molecular Formula: C39H51N5O6
Molecular Weight: 685.8521
MDL Number: MFCD03106493
SMILES: COc1cccc(c1c1cc(nn1c1ccc(cc1C(C)C)C(=O)N(CCCN(C)C)C)C(=O)N[C@]1(C(=O)O)[C@@H]2C[C@@H]3C[C@H]1C[C@H](C2)C3)OC
Properties
Complexity: 1170  
Covalently-Bonded Unit Count: 1  
Heavy Atom Count: 50  
Hydrogen Bond Acceptor Count: 8  
Hydrogen Bond Donor Count: 2  
Rotatable Bond Count: 13  
XLogP3: 3.6  
Literature fold

Title: Cardio-respiratory effects of systemic neurotensin injection are mediated through activation of neurotensin NTS₁ receptors.

Journal: European journal of pharmacology20120915

Title: Different interactions of prolyl oligopeptidase and neurotensin in dopaminergic function of the rat nigrostriatal and mesolimbic pathways.

Journal: Neurochemical research20120901

Title: The neurotensin receptor-1 promotes tumor development in a sporadic but not an inflammation-associated mouse model of colon cancer.

Journal: International journal of cancer20120415

Title: Neurotensin signaling induces intracellular alkalinization and interleukin-8 expression in human pancreatic cancer cells.

Journal: Molecular oncology20090601

Title: Endogenous neurotensin is involved in estrous cycle related alterations in prepulse inhibition of the acoustic startle reflex in female rats.

Journal: Psychoneuroendocrinology20080201

Title: Neurotensin reduces glutamatergic transmission in the dorsolateral striatum via retrograde endocannabinoid signaling.

Journal: Neuropharmacology20080101

Title: Neurotensin antagonist acutely and robustly attenuates locomotion that accompanies stimulation of a neurotensin-containing pathway from rostrobasal forebrain to the ventral tegmental area.

Journal: The European journal of neuroscience20060701

Title: Regulation of DARPP-32 Thr75 phosphorylation by neurotensin in neostriatal neurons: involvement of glutamate signalling.

Journal: The European journal of neuroscience20030901

Title: Neurotensin regulates DARPP-32 thr34 phosphorylation in neostriatal neurons by activation of dopamine D1-type receptors.

Journal: Journal of neurochemistry20020401

Title: Neurotensin induces mating in Saccharomyces cerevisiae cells that express human neurotensin receptor type 1 in place of the endogenous pheromone receptor.

Journal: European journal of biochemistry20010901

Title: Enhanced neurotensin neurotransmission is involved in the clinically relevant behavioral effects of antipsychotic drugs: evidence from animal models of sensorimotor gating.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20010115

Title: Biochemical and pharmacological activities of SR 142948A, a new potent neurotensin receptor antagonist.

Journal: The Journal of pharmacology and experimental therapeutics19970201

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