185055-67-8,MFCD09954121
Catalog No.:AA00AM8W

185055-67-8 | FERROQUINE

Pack Size
Purity
Availability
Price(USD)
Quantity
  
2mg
100%
1 week  
$102.00   $72.00
- +
5mg
100%
1 week  
$140.00   $98.00
- +
10mg
100%
1 week  
$198.00   $139.00
- +
25mg
100%
1 week  
$340.00   $238.00
- +
50mg
100%
1 week  
$540.00   $378.00
- +
100mg
100%
1 week  
$775.00   $543.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA00AM8W
Chemical Name:
FERROQUINE
CAS Number:
185055-67-8
Molecular Formula:
C23H24ClFeN3
Molecular Weight:
433.7548
MDL Number:
MFCD09954121
SMILES:
CN(C[C]12=[CH]3[CH]4=[CH]5[C-]1(CNc1ccnc6c1ccc(c6)Cl)[Fe+2]16782345[CH-]2[CH]1=[CH]7[CH]8=[CH]62)C
Properties
Computed Properties
 
Complexity:
597  
Covalently-Bonded Unit Count:
3  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
28  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0  
Rotatable Bond Count:
5  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  

Literature

Title: Structural characterization and biological evaluation of a clioquinol-ruthenium complex with copper-independent antileukaemic activity.

Journal: Dalton transactions (Cambridge, England : 2003) 20140628

Title: The antimalarial ferroquine: role of the metal and intramolecular hydrogen bond in activity and resistance.

Journal: ACS chemical biology 20110318

Title: Phase I randomized dose-ascending placebo-controlled trials of ferroquine--a candidate anti-malarial drug--in adults with asymptomatic Plasmodium falciparum infection.

Journal: Malaria journal 20110101

Title: Effects of the antimalarial drugs ferroquine and artesunate on Plasmodium yoelii yoelii gametocytegenesis and vectorial transmission.

Journal: Sante (Montrouge, France) 20110101

Title: Synthesis and antimalarial activities of rhenium bioorganometallics based on the 4-aminoquinoline structure.

Journal: Bioorganic & medicinal chemistry 20101115

Title: Enhancement of the antimalarial activity of ciprofloxacin using a double prodrug/bioorganometallic approach.

Journal: Journal of medicinal chemistry 20091224

Title: Ferroquine, an ingenious antimalarial drug: thoughts on the mechanism of action.

Journal: Molecules (Basel, Switzerland) 20081120

Title: Investigation of the redox behavior of ferroquine, a new antimalarial.

Journal: Molecular pharmaceutics 20080101

Title: Design, synthesis, and antimalarial activity of structural chimeras of thiosemicarbazone and ferroquine analogues.

Journal: Bioorganic & medicinal chemistry letters 20071201

Title: In vitro activity of ferroquine (SSR 97193) against Plasmodium falciparum isolates from the Thai-Burmese border.

Journal: Malaria journal 20070101

Title: In vitro activity of ferroquine (SAR97193) is independent of chloroquine resistance in Plasmodium falciparum.

Journal: The American journal of tropical medicine and hygiene 20061201

Title: Probing the role of the covalent linkage of ferrocene into a chloroquine template.

Journal: Journal of medicinal chemistry 20060727

Title: In vitro metabolism of ferroquine (SSR97193) in animal and human hepatic models and antimalarial activity of major metabolites on Plasmodium falciparum.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20060401

Title: Assessment of Plasmodium falciparum resistance to ferroquine (SSR97193) in field isolates and in W2 strain under pressure.

Journal: Malaria journal 20060101

Title: Insights into the mechanism of action of ferroquine. Relationship between physicochemical properties and antiplasmodial activity.

Journal: Molecular pharmaceutics 20050101

Title: Synthesis and antimalarial activity in vitro and in vivo of a new ferrocene-chloroquine analogue.

Journal: Journal of medicinal chemistry 19971107

Title: Keiser J, et al. In vitro and in vivo antischistosomal activity of ferroquine derivatives. Parasit Vectors. 2014 Sep 4;7:424.

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Related Products of 185055-67-8
Tags:185055-67-8 Molecular Formula|185055-67-8 MDL|185055-67-8 SMILES|185055-67-8 FERROQUINE
Catalog No.: AA00AM8W
185055-67-8,MFCD09954121
185055-67-8 | FERROQUINE
Pack Size: 2mg
Purity: 100%
1 week
$102.00 $72.00
Pack Size: 5mg
Purity: 100%
1 week
$140.00 $98.00
Pack Size: 10mg
Purity: 100%
1 week
$198.00 $139.00
Pack Size: 25mg
Purity: 100%
1 week
$340.00 $238.00
Pack Size: 50mg
Purity: 100%
1 week
$540.00 $378.00
Pack Size: 100mg
Purity: 100%
1 week
$775.00 $543.00
Quantity
- +
Add to Card
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bulk Quotation Request
Technical Information
Catalog Number: AA00AM8W
Chemical Name: FERROQUINE
CAS Number: 185055-67-8
Molecular Formula: C23H24ClFeN3
Molecular Weight: 433.7548
MDL Number: MFCD09954121
SMILES: CN(C[C]12=[CH]3[CH]4=[CH]5[C-]1(CNc1ccnc6c1ccc(c6)Cl)[Fe+2]16782345[CH-]2[CH]1=[CH]7[CH]8=[CH]62)C
Properties
Complexity: 597  
Covalently-Bonded Unit Count: 3  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 28  
Hydrogen Bond Acceptor Count: 5  
Hydrogen Bond Donor Count: 1  
Isotope Atom Count: 0  
Rotatable Bond Count: 5  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
Literature fold

Title: Structural characterization and biological evaluation of a clioquinol-ruthenium complex with copper-independent antileukaemic activity.

Journal: Dalton transactions (Cambridge, England : 2003)20140628

Title: The antimalarial ferroquine: role of the metal and intramolecular hydrogen bond in activity and resistance.

Journal: ACS chemical biology20110318

Title: Phase I randomized dose-ascending placebo-controlled trials of ferroquine--a candidate anti-malarial drug--in adults with asymptomatic Plasmodium falciparum infection.

Journal: Malaria journal20110101

Title: Effects of the antimalarial drugs ferroquine and artesunate on Plasmodium yoelii yoelii gametocytegenesis and vectorial transmission.

Journal: Sante (Montrouge, France)20110101

Title: Synthesis and antimalarial activities of rhenium bioorganometallics based on the 4-aminoquinoline structure.

Journal: Bioorganic & medicinal chemistry20101115

Title: Enhancement of the antimalarial activity of ciprofloxacin using a double prodrug/bioorganometallic approach.

Journal: Journal of medicinal chemistry20091224

Title: Ferroquine, an ingenious antimalarial drug: thoughts on the mechanism of action.

Journal: Molecules (Basel, Switzerland)20081120

Title: Investigation of the redox behavior of ferroquine, a new antimalarial.

Journal: Molecular pharmaceutics20080101

Title: Design, synthesis, and antimalarial activity of structural chimeras of thiosemicarbazone and ferroquine analogues.

Journal: Bioorganic & medicinal chemistry letters20071201

Title: In vitro activity of ferroquine (SSR 97193) against Plasmodium falciparum isolates from the Thai-Burmese border.

Journal: Malaria journal20070101

Title: In vitro activity of ferroquine (SAR97193) is independent of chloroquine resistance in Plasmodium falciparum.

Journal: The American journal of tropical medicine and hygiene20061201

Title: Probing the role of the covalent linkage of ferrocene into a chloroquine template.

Journal: Journal of medicinal chemistry20060727

Title: In vitro metabolism of ferroquine (SSR97193) in animal and human hepatic models and antimalarial activity of major metabolites on Plasmodium falciparum.

Journal: Drug metabolism and disposition: the biological fate of chemicals20060401

Title: Assessment of Plasmodium falciparum resistance to ferroquine (SSR97193) in field isolates and in W2 strain under pressure.

Journal: Malaria journal20060101

Title: Insights into the mechanism of action of ferroquine. Relationship between physicochemical properties and antiplasmodial activity.

Journal: Molecular pharmaceutics20050101

Title: Synthesis and antimalarial activity in vitro and in vivo of a new ferrocene-chloroquine analogue.

Journal: Journal of medicinal chemistry19971107

Title: Keiser J, et al. In vitro and in vivo antischistosomal activity of ferroquine derivatives. Parasit Vectors. 2014 Sep 4;7:424.

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