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186534-01-0,MFCD18377781
Catalog No.:AA00ANG5

186534-01-0 | Trimethylpyrazine-2-carboxylic acid

Pack Size
Purity
Availability
Price(USD)
Quantity
  
50mg
95%
3 weeks  
$211.00   $148.00
- +
100mg
95%
3 weeks  
$258.00   $180.00
- +
250mg
95%
3 weeks  
$318.00   $223.00
- +
500mg
95%
3 weeks  
$438.00   $307.00
- +
1g
95%
3 weeks  
$527.00   $369.00
- +
2.5g
95%
3 weeks  
$800.00   $560.00
- +
5g
95%
3 weeks  
$1,258.00   $880.00
- +
10g
95%
3 weeks  
$2,024.00   $1,417.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00ANG5
Chemical Name:
Trimethylpyrazine-2-carboxylic acid
CAS Number:
186534-01-0
Molecular Formula:
C8H10N2O2
Molecular Weight:
166.1772
MDL Number:
MFCD18377781
SMILES:
Cc1nc(C(=O)O)c(nc1C)C
Properties
Properties
 
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
184  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
12  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
1  
XLogP3:
0.8  

Downstream Synthesis Route

[1]Patent:WO2011/105628,2011,A1.Locationinpatent:Page/Pagecolumn78

[1]CurrentPatentAssignee:SHENZHENGANLANBIOMEDICALTECH;SHENZHENOLIVEBIOPHARMACEUTICALS-CN111808032,2020,ALocationinpatent:Paragraph0056-0059

[2]CurrentPatentAssignee:GUANGZHOUMAGPIEPHARMACEUTICALS;GUANGZHOUXIQUEMEDICINE;GUANGZHOUMAGPIEPHARMACEUTICAL-US2019/276413,2019,A1Locationinpatent:Paragraph0076-0077

[3]CurrentPatentAssignee:HEFEIUNIVERSITYOFTECHNOLOGY-CN105153049,2017,BLocationinpatent:Paragraph0066-0071

[4]Wang,Yingfei;Zhang,Xiaojing;Xu,Changjiang;Zhang,Gaoxiao;Zhang,Zaijun;Yu,Pei;Shan,Luchen;Sun,Yewei;Wang,Yuqiang[ChemicalandPharmaceuticalBulletin,2017,vol.65,#4,p.381-388]

[5]CurrentPatentAssignee:CHENGDUBAIYUGINKGOLIDEPHARMACEUTICALS-US2019/77811,2019,A1Locationinpatent:Paragraph0043

[6]Abdelgawad,MohamedA.;Al-Sanea,MohammadM.;Alharbi,KhalidSaad;Eldehna,WagdyM.;Elsayed,ZainabM.;Gomaa,HeshamAM.;Gotina,Lizaveta;Mathew,Bijo;Mohamed,MamdouhF.A.;Parambi,DellaGraceThomas;Youssif,BahaaGM.[DrugDesign,DevelopmentandTherapy,2020,vol.14,p.497-508]

[7]Zhang,Chenze;Yan,Wenqiang;Zhao,Rui;Xu,Bing;Fang,Xiong;Yan,Mengmeng;Zhang,Yuzhong;Wang,Penglong;Lei,Haimin[MedChemComm,2017,vol.8,#3,p.652-656]

[8]CurrentPatentAssignee:3DMEDBEIJINGMEDICINETECH-CN106478760,2017,ALocationinpatent:Paragraph0055;0056;0090;0091

[9]Chen,Hongfei;Li,Guoning;Zhan,Peng;Li,Hong;Wang,Shouxun;Liu,Xinyong[MedChemComm,2014,vol.5,#6,p.711-718]

[10]Chen,Haiyun;Tan,Guolian;Cao,Jie;Zhang,Gaoxiao;Yi,Peng;Yu,Pei;Sun,Yewei;Zhang,Zaijun;Wang,Yuqiang[ChemicalandPharmaceuticalBulletin,2017,vol.65,#1,p.56-65]

[11]CurrentPatentAssignee:KPCPHARMACEUTICALS,INC.-CN104341358,2016,BLocationinpatent:Paragraph0059-0062

[12]Lai,Miao;Ji,Xiaoming;Tao,Tao;Shan,Yuanyuan;Liu,Pengfei;Zhao,Mingqin[JournalofThermalAnalysisandCalorimetry,2017,vol.128,#3,p.1627-1638]

[13]CurrentPatentAssignee:UNIVWEIFANGMEDICAL-CN107118166,2017,ALocationinpatent:Paragraph0021;0026;0031;0036

[14]Wu,Gao-Rong;Xu,Bing;Yang,Yu-Qin;Zhang,Xin-Yu;Fang,Kang;Ma,Tao;Wang,Hui;Xue,Nan-Nan;Chen,Meng;Guo,Wen-Bo;Jia,Xiao-Hui;Wang,Peng-Long;Lei,Hai-Min[EuropeanJournalofMedicinalChemistry,2018,vol.155,p.183-196]

[15]Fang,Kang;Zhang,Xiao-Hua;Han,Yao-Tian;Wu,Gao-Rong;Cai,De-Sheng;Xue,Nan-Nan;Guo,Wen-Bo;Yang,Yu-Qin;Chen,Meng;Zhang,Xin-Yu;Wang,Hui;Ma,Tao;Wang,Peng-Long;Lei,Hai-Min[InternationalJournalofMolecularSciences,2018,vol.19,#10]

[16]Wu,Wenhao;Liang,Xintong;Xie,Guoquan;Chen,Langdi;Liu,Weixiong;Luo,Guolin;Zhang,Peiquan;Yu,Lihong;Zheng,Xuehua;Ji,Hong;Zhang,Chao;Yi,Wei[Molecules,2018,vol.23,#10]

[17]Guo,Wen-Bo;Zhang,Hao;Yan,Wen-Qiang;Liu,Yi-Man;Zhou,Fei;Cai,De-Sheng;Zhang,Wen-Xi;Huang,Xue-Mei;Jia,Xiao-Hui;Chen,Hong-Shan;Qi,Jin-Chai;Wang,Peng-Long;Xu,Bing;Lei,Hai-Min[EuropeanJournalofMedicinalChemistry,2020,vol.185]

[18]Wang,Jiawen;Hong,Ge;Li,Guoliang;Wang,Wenzhi;Liu,Tianjun[Molecules,2019,vol.24,#24]

[19]CurrentPatentAssignee:XINHUOZHIYAOBEIJINGTECH-CN110563739,2019,ALocationinpatent:Paragraph0045;0114;0115

[20]Li,Zhenyu;Yu,Fang;Zhan,Peng;Shen,Yuemao;Liu,Xinyong;Cui,Lei;Wang,Shouxun[MedicinalChemistry,2012,vol.8,#5,p.928-933,6]

[21]CurrentPatentAssignee:TIANJINUNIVERSITY-CN113620889,2021,ALocationinpatent:Paragraph0034-0036;0042

498-00-0    186534-01-0   
4-(hydroxymethyl)-2-methoxyphenyl3,5,6-trimethylpyrazine-2-carboxylate 

[1]CurrentPatentAssignee:LeiPengcheng;ZhangChenze;WangPenglong-CN108456178,2018,ALocationinpatent:Paragraph0122-0124

[2]Zhang,Chenze;Yan,Wenqiang;Zhao,Rui;Xu,Bing;Fang,Xiong;Yan,Mengmeng;Zhang,Yuzhong;Wang,Penglong;Lei,Haimin[MedChemComm,2017,vol.8,#3,p.652-656]

498-00-0    186534-01-0   
2-methoxy-4-(((3,5,6-trimethylpyrazine-2-carbonyl)oxy)methyl)phenyl3,5,6-trimethylpyrazine-2-carboxylate 

[1]Zhang,Chenze;Yan,Wenqiang;Zhao,Rui;Xu,Bing;Fang,Xiong;Yan,Mengmeng;Zhang,Yuzhong;Wang,Penglong;Lei,Haimin[MedChemComm,2017,vol.8,#3,p.652-656]

[2]CurrentPatentAssignee:LeiPengcheng;ZhangChenze;WangPenglong-CN108456178,2018,ALocationinpatent:Paragraph0134-0136

186534-01-0    696-60-6   
N-(4-hydroxybenzyl)-3,5,6-trimethylpyrazine-2-carboxamide 

[1]MedChemComm,2017,vol.8,p.652-656

[2]Patent:CN108456178,2018,A.Locationinpatent:Paragraph0078-0080

Literature

Title: Suppression of blood lipid concentrations by volatile Maillard reaction products.

Journal: Nutrition (Burbank, Los Angeles County, Calif.) 20080101

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Tags:186534-01-0 Molecular Formula|186534-01-0 MDL|186534-01-0 SMILES|186534-01-0 Trimethylpyrazine-2-carboxylic acid