Home Other Building Blocks 15879-93-3
15879-93-3,MFCD00005542
Catalog No.:AA00AOE3

15879-93-3 | alpha-Chloralose

Pack Size
Purity
Availability
Price(USD)
Quantity
  
25g
>85.0%(GC)
in stock  
$95.00   $67.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00AOE3
Chemical Name:
alpha-Chloralose
CAS Number:
15879-93-3
Molecular Formula:
C8H11Cl3O6
Molecular Weight:
309.5283
MDL Number:
MFCD00005542
SMILES:
OC[C@H]([C@H]1O[C@H]2[C@@H]([C@H]1O)O[C@H](O2)C(Cl)(Cl)Cl)O
Properties
Computed Properties
 
Complexity:
285  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
6  
Heavy Atom Count:
17  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
2  
XLogP3:
1  

Literature

Title: Remote pharmacological preconditioning on median nerve territory increases Hsp32 expression and attenuates ischemia-reperfusion injury in rat heart.

Journal: Life sciences 20120515

Title: Low frequency stimulation of the perforant pathway generates anesthesia-specific variations in neural activity and BOLD responses in the rat dentate gyrus.

Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20120201

Title: Magnetic resonance imaging quantification of regional cerebral blood flow and cerebrovascular reactivity to carbon dioxide in normotensive and hypertensive rats.

Journal: NeuroImage 20110901

Title: Different effects of α-chloralose on spontaneous and evoked GABA release in rat hippocampal CA1 neurons.

Journal: Brain research bulletin 20110530

Title: Motion-artifact-free in vivo imaging utilizing narcotized avian embryos in ovo.

Journal: Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 20110401

Title: On the use of α-chloralose for repeated BOLD fMRI measurements in rats.

Journal: Journal of neuroscience methods 20110215

Title: Vasomotion and neurovascular coupling in the visual thalamus in vivo.

Journal: PloS one 20110101

Title: The Knoevenagel-Doebner reaction on 1,2-O-(2,2,2-trichloroethylidene) derivatives of D-gluco- and D-manno-furanose.

Journal: Molecules (Basel, Switzerland) 20101029

Title: Comparison of alpha-chloralose, medetomidine and isoflurane anesthesia for functional connectivity mapping in the rat.

Journal: Magnetic resonance imaging 20100901

Title: Synthesis and antimicrobial activities of two novel amino sugars derived from chloraloses.

Journal: Carbohydrate research 20100719

Title: Exercise changes regional vascular control by commissural NTS in spontaneously hypertensive rats.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20100701

Title: The current functional state of local neuronal circuits controls the magnitude of a BOLD response to incoming stimuli.

Journal: NeuroImage 20100501

Title: Deep thiopental anesthesia alters steady-state glucose homeostasis but not the neurochemical profile of rat cortex.

Journal: Journal of neuroscience research 20100201

Title: Effects of isoflurane and alpha-chloralose anesthesia on BOLD fMRI responses to ingested L-glutamate in rats.

Journal: Neuroscience 20100113

Title: Intracortical microcirculatory change induced by anesthesia in rat somatosensory cortex.

Journal: Advances in experimental medicine and biology 20100101

Title: State-dependent amygdala stimulation-induced cardiovascular effects in rats.

Journal: The Chinese journal of physiology 20091231

Title: Differential effects of anesthetics on cocaine's pharmacokinetic and pharmacodynamic effects in brain.

Journal: The European journal of neuroscience 20091001

Title: Body and brain temperature coupling: the critical role of cerebral blood flow.

Journal: Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20090801

Title: Cardiovascular responses to hydrogen peroxide into the nucleus tractus solitarius.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20090801

Title: Cocaine-induced Fos expression is detectable in the frontal cortex and striatum of rats under isoflurane but not alpha-chloralose anesthesia: implications for FMRI.

Journal: Journal of neuroscience methods 20090730

Title: Isoflurane anesthesia is a valuable alternative for alpha-chloralose anesthesia in the forepaw stimulation model in rats.

Journal: NMR in biomedicine 20090501

Title: Respiratory and cardiovascular effects of biphalin in anaesthetized rats.

Journal: European journal of pharmacology 20090105

Title: Is urethane-chloralose anaesthesia appropriate for pharmacokinetic-pharmacodynamic assessment? Studies with carvedilol.

Journal: Journal of pharmacological and toxicological methods 20090101

Title: alpha-Chloralose diminishes gamma oscillations in rat hippocampal slices.

Journal: Neuroscience letters 20080815

Title: The impact of anesthetics and hyperoxia on cortical spreading depression.

Journal: Experimental neurology 20080701

Title: Intracerebroventricular serotonin reduces the degree of acute hypoxic ventilatory depression in peripherally chemodenervated rabbits.

Journal: The Chinese journal of physiology 20080630

Title: Weakened long-range correlation of renal sympathetic nerve activity in Wistar rats after anaesthesia.

Journal: Neuroscience letters 20080305

Title: Alpha-chloralose is a suitable anesthetic for chronic focal cerebral ischemia studies in the rat: a comparative study.

Journal: Brain research 20080129

Title: Coupling between simultaneously recorded BOLD response and neuronal activity in the rat somatosensory cortex.

Journal: NeuroImage 20080115

Title: Relevance of anaesthesia for dofetilide-induced torsades de pointes in alpha1-adrenoceptor-stimulated rabbits.

Journal: British journal of pharmacology 20080101

Title: Successful treatment of capture myopathy in three wild greater sandhill cranes (Grus canadensis tabida).

Journal: Journal of avian medicine and surgery 20071201

Title: Cardiac vagal preganglionic neurones in the intermediate zone of the brainstem in anaesthetized cats.

Journal: Experimental physiology 20071101

Title: Effects of NMDA receptor antagonists on visceromotor reflexes and on intestinal motility, in vivo.

Journal: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20070701

Title: Functional uncoupling of hemodynamic from neuronal response by inhibition of neuronal nitric oxide synthase.

Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20070401

Title: Ethanol inhibits the sensory responses of cerebellar granule cells in anesthetized cats.

Journal: Alcoholism, clinical and experimental research 20070201

Title: Effects of pulse lung inflation on chest wall expiratory motor activity.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20070101

Title: Effects of sildenafil on hypoxic pulmonary vascular function in dogs.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20061001

Title: Negative chronotropic effect of cannabinoids and their water-soluble emulsion is related to activation of cardiac CB1 receptors.

Journal: Bulletin of experimental biology and medicine 20061001

Title: Increased oxygen consumption in the somatosensory cortex of alpha-chloralose anesthetized rats during forepaw stimulation determined using MRS at 11.7 Tesla.

Journal: NeuroImage 20060901

Title: Comparison of urethane/chloralose and pentobarbitone anaesthesia for examining effects of bacterial lipopolysaccharide in mice.

Journal: Fundamental & clinical pharmacology 20060801

Title: Alpha-chloralose poisoning in dogs and cats: a retrospective study of 33 canine and 13 feline confirmed cases.

Journal: Veterinary journal (London, England : 1997) 20060701

Title: Biologically relevant phosphoranes: structural characterization of glucofuranose- and xylofuranose-based phosphoranes.

Journal: Inorganic chemistry 20060403

Title: A fully noninvasive and robust experimental protocol for longitudinal fMRI studies in the rat.

Journal: NeuroImage 20060215

Title: Inverse-orthostasis may induce elevation of blood pressure due to sympathetic activation.

Journal: Journal of cardiovascular pharmacology 20060201

Title: Mapping brain activity following administration of a nicotinic acetylcholine receptor agonist, ABT-594, using functional magnetic resonance imaging in awake rats.

Journal: Neuroscience 20060101

Title: Metabolic alterations in focally activated primary somatosensory cortex of alpha-chloralose-anesthetized rats measured by 1H MRS at 11.7 T.

Journal: NeuroImage 20051101

Title: Measurement of unbound cocaine in blood, brain and bile of anesthetized rats using microdialysis coupled with liquid chromatography and verified by tandem mass spectrometry.

Journal: Biomedical chromatography : BMC 20050601

Title: In vivo alpha-adrenergic responses and troponin I phosphorylation: anesthesia interactions.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20050401

Title: Experimental orthostasis elicits sustained hypertension, which can be prevented by sympathetic blockade in the rat.

Journal: Journal of cardiovascular pharmacology 20050401

Title: Ex vivo NMR study of lactate metabolism in rat brain under various depressed states.

Journal: Journal of neuroscience research 20050101

Title: Negative inotropic action of propofol is enhanced in the acute ischemic myocardium of dogs.

Journal: Journal of anesthesia 20050101

Title: Comparison of the effects of dexmedetomidine and esmolol on myocardial oxygen consumption in dogs.

Journal: European journal of anaesthesiology 20041201

Title: Ex vivo analysis of lactate and glucose metabolism in the rat brain under different states of depressed activity.

Journal: The Journal of biological chemistry 20041112

Title: Kidney function in mice: thiobutabarbital versus alpha-chloralose anesthesia.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20041001

Title: [Curarization for contributing symptomatic treatment of myoclonic jerks induced by chloralose poisoning].

Journal: Annales francaises d'anesthesie et de reanimation 20040401

Title: Thermogenesis elicited by skin cooling in anaesthetized rats: lack of contribution of the cerebral cortex.

Journal: The Journal of physiology 20040301

Title: In vivo experimental approach for the risk assessment of fluoroquinolone antibacterial agents-induced long QT syndrome.

Journal: European journal of pharmacology 20040220

Title: The effects of sham and full spinalization on the antinociceptive effects of NCX-701 (nitroparacetamol) in monoarthritic rats.

Journal: Neuropharmacology 20030901

Title: Contradicting a unitary theory of general anesthetic action: a history of three compounds from 1901 to 2001.

Journal: Bulletin of anesthesia history 20030701

Title: Exercise pressor reflex in decerebrate and anesthetized rats.

Journal: American journal of physiology. Heart and circulatory physiology 20030601

Title: 1H NMR spectroscopy and GC-MS analysis of alpha-chloralose. Application to two poisoning cases.

Journal: Journal of analytical toxicology 20030401

Title: Noradrenaline, infused locally, reduces arrhythmia severity during coronary artery occlusion in anaesthetised dogs.

Journal: Cardiovascular research 20020701

Title: Wavelet decomposition of cardiovascular signals for baroreceptor function tests in pigs.

Journal: IEEE transactions on bio-medical engineering 20020701

Title: Centrally applied nitric oxide donor elevates plasma corticosterone by activation of the hypothalamic noradrenergic neurons in rats.

Journal: Brain research 20020607

Title: 5-Hydroxytryptamine(1B/1D) and 5-hydroxytryptamine1F receptors inhibit capsaicin-induced c-fos immunoreactivity within mouse trigeminal nucleus caudalis.

Journal: Cephalalgia : an international journal of headache 20020601

Title: Dose-related attenuation of cardiac sympathetic nerve activity and intracardiac conduction with thoracic epidural clonidine in alpha-chloralose-anesthetized cats.

Journal: Osaka city medical journal 20020601

Title: Fentanyl-fluanisone-midazolam combination results in more stable hemodynamics than does urethane alpha-chloralose and 2,2,2-tribromoethanol in mice.

Journal: Contemporary topics in laboratory animal science 20020501

Title: GLP-1-(9-36) amide reduces blood glucose in anesthetized pigs by a mechanism that does not involve insulin secretion.

Journal: American journal of physiology. Endocrinology and metabolism 20020401

Title: Selective suppression of late laryngeal adductor responses by N-methyl-D-aspartate receptor blockade in the cat.

Journal: Journal of neurophysiology 20020301

Title: Serotonin(3) receptor stimulation in the nucleus tractus solitarii activates non-catecholaminergic neurons in the rat ventrolateral medulla.

Journal: Neuroscience 20020101

Title: Gadolinium attenuates exercise pressor reflex in cats.

Journal: American journal of physiology. Heart and circulatory physiology 20010501

Title: The actions of ether, alcohol and alkane general anaesthetics on GABAA and glycine receptors and the effects of TM2 and TM3 mutations.

Journal: British journal of pharmacology 20000201

Title: Naloxone does not prevent apomorphine-induced emesis or hypotension in dogs.

Journal: Clinical autonomic research : official journal of the Clinical Autonomic Research Society 19941201

Title: The comparison of effects of various anesthetics on expression of Fos protein in the rat brain.

Journal: Neuroscience letters 19940718

Title: The electrophysiological effects of alpha-chloralose anesthesia in the intact dog: (1) alone and (2) in combination with verapamil.

Journal: Pacing and clinical electrophysiology : PACE 19890201

Title: Protective effect of verapamil upon ouabain-induced cardiac arrhythmias.

Journal: Pharmacology 19880101

Title: Effect of controlled ventilation on renal and splanchnic blood flows during nicotine.

Journal: The American journal of physiology 19850301

Title: Mechanisms of central prostaglandin E2 hypertension in conscious dogs, sheep, and calves.

Journal: The American journal of physiology 19840801

Title: Effects of lysine-vasopressin and oxytocin on central cardiovascular control.

Journal: British journal of pharmacology 19820901

Title: Influence of several anesthetic agents on the effect of delta9-tetrahydrocannabinol on the heart rate and blood pressure of the mongrel dog.

Journal: European journal of pharmacology 19770701

Title: Motor and electrical signs of epileptiform activity induced by penicillin in the spinal cords of decapitate cats.

Journal: Electroencephalography and clinical neurophysiology 19760901

Title: Suppression of ouabain-induced atrial arrhythmias by carotid sinus stimulation.

Journal: British journal of pharmacology and chemotherapy 19610801

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Tags:15879-93-3 Molecular Formula|15879-93-3 MDL|15879-93-3 SMILES|15879-93-3 alpha-Chloralose