[1]Kim,SungSoo;Nehru,Kasi[Synlett,2002,#4,p.616-618]
[2]Locationinpatent:experimentalpartKumpulainen,EsaT.T.;Koskinen,AriM.P.[Chemistry-AEuropeanJournal,2009,vol.15,#41,p.10901-10911]
[3]Carman,RaymondM.;Garner,A.Christopher[AustralianJournalofChemistry,1996,vol.49,#7,p.741-749]
[4]Muelbaier;Giannis[AngewandteChemie-InternationalEdition,2001,vol.40,#23,p.4393-4394]
[5]Locationinpatent:experimentalpartLin,Cheng-Kun;Lu,Ta-Jung[Tetrahedron,2010,vol.66,#51,p.9688-9693]
[6]Chen,Ba-Tian;Bukhryakov,KonstantinV.;Sougrat,Rachid;Rodionov,ValentinO.[ACSCatalysis,2015,vol.5,#2,p.1313-1317]
[7]Nandurkar,NitinS.;Zhang,Jianjun;Ye,Qing;Ponomareva,LarissaV.;She,Qing-Bai;Thorson,JonS.[JournalofMedicinalChemistry,2014,vol.57,#17,p.7478-7484]
[8]Walsh,Katie;Sneddon,HelenF.;Moody,ChristopherJ.[OrganicLetters,2014,vol.16,#19,p.5224-5227]
[9]Yan,Qi;Fang,YeChen;Jia,YunXue;Duan,XinHong[NewJournalofChemistry,2017,vol.41,#6,p.2372-2377]
[10]Wang,Qian;Fan,ShiYan;Wong,HenryN.C.;Li,Zhong;Fung,BingM.;Twieg,RobertJ.;Nguyen,HuuTinh[Tetrahedron,1993,vol.49,#3,p.619-638]
[11]Surburg,Horst;Mondon,Albert[ChemischeBerichte,1981,vol.<193>114,#1,p.118-131]
[12]Kergomard;Philibert-Bigou[BulletindelaSocieteChimiquedeFrance,1958,p.393]
[13]Ishihara,Kazuaki;Kurihara,Hideki;Yamamoto,Hisashi[JournalofOrganicChemistry,1997,vol.62,#17,p.5664-5665]
[14]Rigoli,JaredW.;Moyer,SaraA.;Pearce,SimonD.;Schomaker,JenniferM.[OrganicandBiomolecularChemistry,2012,vol.10,#9,p.1746-1749]
[15]Mitchell,LornaJ.;Moody,ChristopherJ.[JournalofOrganicChemistry,2014,vol.79,#22,p.11091-11100]
[16]Bhaumik,Chanchal;Stein,Dominique;Vincendeau,Sandrine;Poli,Rinaldo;Manoury,Éric[ComptesRendusChimie,2016,vol.19,#5,p.566-570]
[17]DeSousa,DamiãoPergentino;Lima,TamiresCardoso;Steverding,Dietmar[PlantaMedica,2016,vol.82,#15,p.1346-1350]
[18]Lagerspets,Emi;Valbonetti,Evelyn;Eronen,Aleksi;Repo,Timo[Molecularcatalysis,2021,vol.509]
[19]Abba,Donatella;Eronen,Aleksi;Lagerspets,Emi;Repo,Timo;Sharratt,Joseph[Molecularcatalysis,2022,vol.520]
[1]Geoghegan,Kimberly;Evans,Paul[TetrahedronLetters,2014,vol.55,#8,p.1431-1433]
[2]CurrentPatentAssignee:SHENYANGPHARMACEUTICALUNIVERSITY-CN104945334,2018,BLocationinpatent:Paragraph0027;0028
[3]Carman,RaymondM.;Garner,A.Christopher[AustralianJournalofChemistry,1996,vol.49,#7,p.741-749]
[4]Hui,Zi;Zhang,Meihui;Cong,Lin;Xia,Mingyu;Dong,Jinhua[Molecules,2014,vol.19,#5,p.6671-6682]
[5]Schmidt[ChemischeBerichte,1950,vol.83,p.193][ChemischeBerichte,1955,vol.88,p.453,455]
[1]Fleischer,Steffen;Zhou,Shaolin;Junge,Kathrin;Beller,Matthias[AngewandteChemie-InternationalEdition,2013,vol.52,#19,p.5120-5124][Angew.Chem.,2013,vol.125,#19,p.5224-5228]
[2]Wienhöfer,Gerrit;Westerhaus,FelixA.;Junge,Kathrin;Ludwig,Ralf;Beller,Matthias[Chemistry-AEuropeanJournal,2013,vol.19,#24,p.7701-7707]
[3]Fisher,GaryB.;Fuller,JosephC.;Harrison,John;Alvarez,SalvadorG.;Burkhardt,ElizabethR.;etal.[JournalofOrganicChemistry,1994,vol.59,#21,p.6378-6385]
[4]Buchecker;Marti;Eugster[HelveticaChimicaActa,1982,vol.65,#3,p.896-912]
[5]Hui,Zi;Zhang,Meihui;Cong,Lin;Xia,Mingyu;Dong,Jinhua[Molecules,2014,vol.19,#5,p.6671-6682]
[6]CurrentPatentAssignee:SHENYANGPHARMACEUTICALUNIVERSITY-CN104945334,2018,BLocationinpatent:Paragraph0025;0026
[7]CurrentPatentAssignee:SHENYANGPHARMACEUTICALUNIVERSITY-CN104945335,2018,BLocationinpatent:Paragraph0028;0029
[8]Plank,TaylorN.;Drake,JessicaL.;Kim,DanielK.;Funk,TimothyW.[AdvancedSynthesisandCatalysis,2012,vol.354,#4,p.597-601]
[9]Farrar-Tobar,RonaldA.;Wei,Zhihong;Jiao,Haijun;Hinze,Sandra;deVries,JohannesG.[Chemistry-AEuropeanJournal,2018,vol.24,#11,p.2725-2734]
[10]Locationinpatent:schemeortableSantosPisoni,Diegodos;SobieskidaCosta,Jessé;Gamba,Douglas;Petzhold,CesarLiberato;CésardeAmorimBorges,Antonio;Ceschi,MarcoAntonio;Lunardi,Paula;SaraivaGonçalves,CarlosAlberto[EuropeanJournalofMedicinalChemistry,2010,vol.45,#2,p.526-535]
[11]Rigoli,JaredW.;Moyer,SaraA.;Pearce,SimonD.;Schomaker,JenniferM.[OrganicandBiomolecularChemistry,2012,vol.10,#9,p.1746-1749]
[12]Christie,Francesca;Zanotti-Gerosa,Antonio;Grainger,Damian[ChemCatChem,2018,vol.10,#5,p.1012-1018]
[13]Wu,Xiang;Wang,Hai-Jun;Huang,Yong-Shuang;Li,Wei-DongZ.[OrganicLetters,2018,vol.20,#7,p.1871-1874]
[14]Dyrkheeva,NadezhdaS.;Filimonov,AleksandrS.;Luzina,OlgaA.;Zakharenko,AlexandraL.;Ilina,EkaterinaS.;Malakhova,AnastasiaA.;Medvedev,SergeyP.;Reynisson,Jóhannes;Volcho,KonstantinP.;Zakian,SurenM.;Salakhutdinov,NarimanF.;Lavrik,OlgaI.[Biomolecules,2021,vol.11,#7]
[1]Mori,Kenji[TetrahedronAsymmetry,2006,vol.17,#14,p.2133-2142]
[2]Marshall,JamesA.;Sehon,ClarkA.[JournalofOrganicChemistry,1997,vol.62,#13,p.4313-4320]
[3]Kamiya,Akinobu;Kawamoto,Yuichiro;Kobayashi,Toyoharu;Ito,Hisanaka[OrganicLetters,2021,vol.23,#17,p.6916-6918]
[4]Marshall,JamesA.;VanDevender,ElvaA.[JournalofOrganicChemistry,2001,vol.66,#24,p.8037-8041]
[5]Marshall,JamesA.;Bartley,GaryS.;Wallace,EliM.[JournalofOrganicChemistry,1996,vol.61,#17,p.5729-5735]
[6]CurrentPatentAssignee:NORTHEASTERNUNIVERSITYINBOSTON,MASSACHUSETTS-WO2014/62965,2014,A1Locationinpatent:Paragraph0210
[7]Mordini,Alessandro;Pecchi,Sabina;Capozzi,Giuseppe;Capperucci,Antonella;Degl'Innocenti,Alessandro;etal.[JournalofOrganicChemistry,1994,vol.59,#17,p.4784-4790]
[8]Villa,AidaL.;DeVos,DirkE.;Verpoort,Francis;Sels,BertF.;Jacobs,PierreA.[JournalofCatalysis,2001,vol.198,#2,p.223-231]
[9]Sparks,StevenM.;Chow,ChunP.;Zhu,Liang;Shea,KennethJ.[JournalofOrganicChemistry,2004,vol.69,#9,p.3025-3035]
[10]Stevens,RobertV.;Albizati,KimF.[JournalofOrganicChemistry,1985,vol.50,#5,p.632-640]
[11]Almeida,LeandroD.;Delolo,FábioG.;Costa,AlexandreP.S.;Gusevskaya,ElenaV.;Robles-Azocar,PatriciaA.[Molecularcatalysis,2022,vol.527]
[1]Tanner,David;Andersson,PherG.;Tedenborg,Lars;Somfai,Peter[Tetrahedron,1994,vol.50,#30,p.9135-9144]
[2]Schomaker,JenniferM.;Pulgam,VeeraReddy;Borhan,Babak[JournaloftheAmericanChemicalSociety,2004,vol.126,#42,p.13600-13601]
Title: The isoprenoid perillyl alcohol inhibits telomerase activity in prostate cancer cells.
Journal: Biochimie 20121201
Title: Analysis of EGF+61A>G polymorphism and EGF serum levels in Brazilian glioma patients treated with perillyl alcohol-based therapy.
Journal: Journal of cancer research and clinical oncology 20120801
Title: Calcium blockers decrease the bortezomib resistance in mantle cell lymphoma via manipulation of tissue transglutaminase activities.
Journal: Blood 20120315
Title: Influence of the active compounds of Perilla frutescens leaves on lipid membranes.
Journal: Journal of natural products 20120224
Title: Anticancer efficacy of perillyl alcohol-bearing PLGA microparticles.
Journal: International journal of nanomedicine 20120101
Title: Microbial hydroxylation of S-(-)-perillyl alcohol by Fusarium heterosporium.
Journal: Natural product communications 20111201
Title: Nonmelanoma skin cancer chemoprevention.
Journal: Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20111101
Title: Cell physiology rather than enzyme kinetics can determine the efficiency of cytochrome P450-catalyzed C-H-oxyfunctionalization.
Journal: Journal of industrial microbiology & biotechnology 20110901
Title: Evaluation of the antioxidant and antiproliferative potential of bioflavors.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20110701
Title: An efficient route to selective bio-oxidation catalysts: an iterative approach comprising modeling, diversification, and screening, based on CYP102A1.
Journal: Chembiochem : a European journal of chemical biology 20110614
Title: Efficacy of monoterpene perillyl alcohol upon survival rate of patients with recurrent glioblastoma.
Journal: Journal of cancer research and clinical oncology 20110201
Title: Perillyl alcohol protects against ethanol induced acute liver injury in Wistar rats by inhibiting oxidative stress, NFκ-B activation and proinflammatory cytokine production.
Journal: Toxicology 20110111
Title: Chemo-resistant protein expression pattern of glioblastoma cells (A172) to perillyl alcohol.
Journal: Journal of proteome research 20110107
Title: The anticancer drug perillyl alcohol is a Na/K-ATPase inhibitor.
Journal: Molecular and cellular biochemistry 20101201
Title: Dynamic proteomic overview of glioblastoma cells (A172) exposed to perillyl alcohol.
Journal: Journal of proteomics 20100310
Title: A phase 2a study of topical perillyl alcohol cream for chemoprevention of skin cancer.
Journal: Cancer prevention research (Philadelphia, Pa.) 20100201
Title: The promise of natural products for blocking early events in skin carcinogenesis.
Journal: Cancer prevention research (Philadelphia, Pa.) 20100201
Title: Perillyl alcohol and methyl jasmonate sensitize cancer cells to cisplatin.
Journal: Anti-cancer drugs 20100101
Title: Correlation of tumor topography and peritumoral edema of recurrent malignant gliomas with therapeutic response to intranasal administration of perillyl alcohol.
Journal: Investigational new drugs 20091201
Title: Tricistronic overexpression of cytochrome P450cam, putidaredoxin, and putidaredoxin reductase provides a useful cell-based catalytic system.
Journal: Biotechnology letters 20090901
Title: Perillyl alcohol attenuates Ras-ERK signaling to inhibit murine skin inflammation and tumorigenesis.
Journal: Chemico-biological interactions 20090515
Title: Components of lemon essential oil attenuate dementia induced by scopolamine.
Journal: Nutritional neuroscience 20090401
Title: Protective effects of mastic oil from Pistacia lentiscus variation chia against experimental growth of lewis lung carcinoma.
Journal: Nutrition and cancer 20090101
Title: High-performance liquid chromatographic and pharmacokinetic analyses of an intravenous submicron emulsion of perillyl alcohol in rats.
Journal: Journal of pharmaceutical and biomedical analysis 20081201
Title: Fragrance material review on p-mentha-1,8-dien-7-ol.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20081101
Title: Mechanism of in vitro pancreatic cancer cell growth inhibition by melanoma differentiation-associated gene-7/interleukin-24 and perillyl alcohol.
Journal: Cancer research 20080915
Title: Preliminary results from a phase I/II study of perillyl alcohol intranasal administration in adults with recurrent malignant gliomas.
Journal: Surgical neurology 20080901
Title: Ras pathway activation in gliomas: a strategic target for intranasal administration of perillyl alcohol.
Journal: Archivum immunologiae et therapiae experimentalis 20080801
Title: Synthesis of phosphatidylated-monoterpene alcohols catalyzed by phospholipase D and their antiproliferative effects on human cancer cells.
Journal: Bioorganic & medicinal chemistry letters 20080715
Title: Chemoprevention by perillyl alcohol coupled with viral gene therapy reduces pancreatic cancer pathogenesis.
Journal: Molecular cancer therapeutics 20080701
Title: A pilot study of perillyl alcohol in pancreatic cancer.
Journal: The Journal of surgical research 20080615
Title: Phase II trial of daily oral perillyl alcohol (NSC 641066) in treatment-refractory metastatic breast cancer.
Journal: Cancer chemotherapy and pharmacology 20080601
Title: Anti-inflammatory senescence actives 5203-L molecule to promote healthy aging and prolongation of lifespan.
Journal: Rejuvenation research 20080401
Title: Phase 1 study of topical perillyl alcohol cream for chemoprevention of skin cancer.
Journal: Nutrition and cancer 20080101
Title: Anti-thrombin as a prognostic biomarker candidate for patients with recurrent glioblastoma multiform under treatment with perillyl alcohol.
Journal: Journal of experimental therapeutics & oncology 20080101
Title: Perillyl alcohol and perillic acid induced cell cycle arrest and apoptosis in non small cell lung cancer cells.
Journal: Cancer letters 20071118
Title: Modifications of the chemical structure of terpenes in antiplasmodial and antifungal drug research.
Journal: Bioorganic & medicinal chemistry letters 20071115
Title: Perillyl alcohol and genistein differentially regulate PKB/Akt and 4E-BP1 phosphorylation as well as eIF4E/eIF4G interactions in human tumor cells.
Journal: Archives of biochemistry and biophysics 20070901
Title: Cell cycle arrest by the isoprenoids perillyl alcohol, geraniol, and farnesol is mediated by p21(Cip1) and p27(Kip1) in human pancreatic adenocarcinoma cells.
Journal: The Journal of pharmacology and experimental therapeutics 20070301
Title: Anaplastic oligodendroglioma responding favorably to intranasal delivery of perillyl alcohol: a case report and literature review.
Journal: Surgical neurology 20061201
Title: Polycyclic aromatic hydrocarbon-induced CYP1B1 activity is suppressed by perillyl alcohol in MCF-7 cells.
Journal: Toxicology and applied pharmacology 20060601
Title: Perillyl alcohol inhibits the expression and function of the androgen receptor in human prostate cancer cells.
Journal: Cancer letters 20060518
Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.
Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Title: Recent advances in the molecular genetics of malignant gliomas disclose targets for antitumor agent perillyl alcohol.
Journal: Surgical neurology 20060101
Title: Perillyl alcohol induces c-Myc-dependent apoptosis in Bcr/Abl-transformed leukemia cells.
Journal: Oncology 20060101
Title: Mastic oil from Pistacia lentiscus var. chia inhibits growth and survival of human K562 leukemia cells and attenuates angiogenesis.
Journal: Nutrition and cancer 20060101
Title: In vitro induction of apoptosis in U937 cells by perillyl alcohol with sensitization by pentoxifylline: increased BCL-2 and BAX protein expression.
Journal: Chemotherapy 20060101
Title: Effects of perillyl alcohol and heat shock treatment in gene expression of human lung adenocarcinoma cell line A549.
Journal: Journal of experimental therapeutics & oncology 20060101
Title: Perillyl alcohol inhibits a calcium-dependent constitutive nuclear factor-kappaB pathway.
Journal: Cancer research 20050915
Title: Effect of D-limonene on immune response in BALB/c mice with lymphoma.
Journal: International immunopharmacology 20050501
Title: Perillyl alcohol induces apoptosis in human glioblastoma multiforme cells.
Journal: Oncology reports 20050501
Title: CaaX-prenyltransferases are essential for expression of genes involvedin the early stages of monoterpenoid biosynthetic pathway in Catharanthus roseus cells.
Journal: Plant molecular biology 20050401
Title: An HPLC method for quantitation of perillyl alcohol in a topical pharmaceutical cream formulation.
Journal: Journal of pharmaceutical and biomedical analysis 20050309
Title: Protein and m-RNA expression of farnesyl-transferases, RhoA and RhoB in rat liver hepatocytes: action of perillyl alcohol and vitamin A in vivo.
Journal: Journal of biomedical science 20050101
Title: A pilot surrogate end point biomarker trial of perillyl alcohol in breast neoplasia.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20041115
Title: Perillyl alcohol is an angiogenesis inhibitor.
Journal: The Journal of pharmacology and experimental therapeutics 20041101
Title: A phase I trial of perillyl alcohol administered four times daily for 14 days out of 28 days.
Journal: Cancer chemotherapy and pharmacology 20041001
Title: Perillyl alcohol inhibits human breast cancer cell growth in vitro and in vivo.
Journal: Breast cancer research and treatment 20040401
Title: Perillyl alcohol-mediated inhibition of lung cancer cell line proliferation: potential mechanisms for its chemotherapeutic effects.
Journal: Toxicology and applied pharmacology 20040301
Title: Development of a perillyl alcohol topical cream formulation.
Journal: International journal of pharmaceutics 20040128
Title: Effects of POH in combination with STI571 on the proliferation and apoptosis of K562 cells.
Journal: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20040101
Title: Monoterpenes enhanced the sensitivity of head and neck cancer cells to radiation treatment in vitro.
Journal: Anticancer research 20040101
Title: Effect of antiproliferative agents on vascular function in normal and in vitro balloon-injured porcine coronary arteries.
Journal: European journal of pharmacology 20031114
Title: Phase I trial of perillyl alcohol administered four times daily continuously.
Journal: Cancer chemotherapy and pharmacology 20031101
Title: Cytotoxicity of perillyl alcohol against cancer cells is potentiated by hyperthermia.
Journal: International journal of radiation oncology, biology, physics 20031101
Title: Perillyl alcohol and perillaldehyde induced cell cycle arrest and cell death in BroTo and A549 cells cultured in vitro.
Journal: Life sciences 20031017
Title: Studies with cytotoxic agents suggest that apoptosis is not a major determinant of clonogenic death in neuroblastoma cells.
Journal: European journal of cancer (Oxford, England : 1990) 20031001
Title: Anti-leukemia effect of perillyl alcohol in Bcr/Abl-transformed cells indirectly inhibits signaling through Mek in a Ras- and Raf-independent fashion.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20031001
Title: Perillyl alcohol as a radio-/chemosensitizer in malignant glioma.
Journal: The Journal of biological chemistry 20030919
Title: Perillyl alcohol mediated radiosensitization via augmentation of the Fas pathway in prostate cancer cells.
Journal: The Prostate 20030915
Title: Phase II trial of perillyl alcohol (NSC 641066) administered daily in patients with metastatic androgen independent prostate cancer.
Journal: Investigational new drugs 20030801
Title: Monoterpene regulation of Ras and Ras-related protein expression.
Journal: Journal of lipid research 20030601
Title: A phase I trial of perillyl alcohol in patients with advanced solid tumors.
Journal: Cancer chemotherapy and pharmacology 20030601
Title: Perillyl alcohol as a chemopreventive agent in N-nitrosomethylbenzylamine-induced rat esophageal tumorigenesis.
Journal: Cancer research 20030515
Title: Effects of perillyl alcohol in glial C6 cell line in vitro and anti-metastatic activity in chorioallantoic membrane model.
Journal: International journal of molecular medicine 20021201
Title: Monoterpenes inhibit proliferation of human colon cancer cells by modulating cell cycle-related protein expression.
Journal: Cancer letters 20020726
Title: Effects of perillyl alcohol on melanoma in the TPras mouse model.
Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20020601
Title: A phase II trial of daily perillyl alcohol in patients with advanced ovarian cancer: Eastern Cooperative Oncology Group Study E2E96.
Journal: Gynecologic oncology 20020601
Title: Metabolism of (+)- and (-)-limonenes to respective carveols and perillyl alcohols by CYP2C9 and CYP2C19 in human liver microsomes.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20020501
Title: Antileukemia activity of perillyl alcohol (POH): uncoupling apoptosis from G0/G1 arrest suggests that the primary effect of POH on Bcr/Abl-transformed cells is to induce growth arrest.
Journal: Leukemia 20020201
Title: Induction of cytostasis in mammary carcinoma cells treated with the anticancer agent perillyl alcohol.
Journal: Carcinogenesis 20020101
Title: Sex differences in the metabolism of (+)- and (-)-limonene enantiomers to carveol and perillyl alcohol derivatives by cytochrome p450 enzymes in rat liver microsomes.
Journal: Chemical research in toxicology 20020101
Title: Phase I study of perillyl alcohol in patients with refractory malignancies.
Journal: Cancer biology & therapy 20020101
Title: Effects of the isoprenoids perillyl alcohol and farnesol on apoptosis biomarkers in pancreatic cancer chemoprevention.
Journal: Anticancer research 20020101
Title: Phase II trial of perillyl alcohol in patients with metastatic colorectal cancer.
Journal: International journal of gastrointestinal cancer 20020101
Title: Liston BW, et al. Perillyl alcohol as a chemopreventive agent in N-nitrosomethylbenzylamine-induced rat esophageal tumorigenesis. Cancer Res. 2003 May 15;63(10):2399-403.