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1445605-23-1,MFCD22576450
Catalog No.:AA00AS2A

1445605-23-1 | Lu AF21934

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$63.00   $44.00
- +
5mg
98%
in stock  
$69.00   $48.00
- +
25mg
98%
in stock  
$116.00   $82.00
- +
100mg
98%
in stock  
$259.00   $182.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA00AS2A
Chemical Name:
Lu AF21934
CAS Number:
1445605-23-1
Molecular Formula:
C14H16Cl2N2O2
Molecular Weight:
315.1950
MDL Number:
MFCD22576450
SMILES:
O=C([C@H]1CCCC[C@H]1C(=O)N)Nc1ccc(c(c1)Cl)Cl
Properties
Computed Properties
 
Complexity:
378  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
2  
Heavy Atom Count:
20  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
3  
XLogP3:
2.4  

Literature

Title: Synergy between L-DOPA and a novel positive allosteric modulator of metabotropic glutamate receptor 4: implications for Parkinson's disease treatment and dyskinesia.

Journal: Neuropharmacology 20130301

Title: Anna Sławińska, et al. Anxiolytic- but not antidepressant-like activity of Lu AF21934, a novel, selective positive allosteric modulator of the mGlu? receptor. Neuropharmacology. 2013 Mar;66:225-35.

Title: Ossowska K, et al. Lu AF21934, a positive allosteric modulator of mGlu4 receptors, reduces the harmaline-induced hyperactivity but not tremor in rats. Neuropharmacology. 2014 Aug;83:28-35.

Title: Anna Sławińska, et al. The antipsychotic-like effects of positive allosteric modulators of metabotropic glutamate mGlu4 receptors in rodents. Br J Pharmacol. 2013 Aug;169(8):1824-39.

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SDS
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Tags:1445605-23-1 Molecular Formula|1445605-23-1 MDL|1445605-23-1 SMILES|1445605-23-1 Lu AF21934
Catalog No.: AA00AS2A
1445605-23-1,MFCD22576450
1445605-23-1 | Lu AF21934
Pack Size： 1mg
Purity： ≥98%
in stock
$63.00 $44.00
Pack Size： 5mg
Purity： 98%
in stock
$69.00 $48.00
Pack Size： 25mg
Purity： 98%
in stock
$116.00 $82.00
Pack Size： 100mg
Purity： 98%
in stock
$259.00 $182.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA00AS2A
Chemical Name: Lu AF21934
CAS Number: 1445605-23-1
Molecular Formula: C14H16Cl2N2O2
Molecular Weight: 315.1950
MDL Number: MFCD22576450
SMILES: O=C([C@H]1CCCC[C@H]1C(=O)N)Nc1ccc(c(c1)Cl)Cl
Properties
Complexity: 378  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 2  
Heavy Atom Count: 20  
Hydrogen Bond Acceptor Count: 2  
Hydrogen Bond Donor Count: 2  
Rotatable Bond Count: 3  
XLogP3: 2.4  
Literature fold

Title: Synergy between L-DOPA and a novel positive allosteric modulator of metabotropic glutamate receptor 4: implications for Parkinson's disease treatment and dyskinesia.

Journal: Neuropharmacology20130301

Title: Anna Sławińska, et al. Anxiolytic- but not antidepressant-like activity of Lu AF21934, a novel, selective positive allosteric modulator of the mGlu? receptor. Neuropharmacology. 2013 Mar;66:225-35.

Title: Ossowska K, et al. Lu AF21934, a positive allosteric modulator of mGlu4 receptors, reduces the harmaline-induced hyperactivity but not tremor in rats. Neuropharmacology. 2014 Aug;83:28-35.

Title: Anna Sławińska, et al. The antipsychotic-like effects of positive allosteric modulators of metabotropic glutamate mGlu4 receptors in rodents. Br J Pharmacol. 2013 Aug;169(8):1824-39.

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