Home Other Heterocycles 194093-42-0
194093-42-0,MFCD00939557
Catalog No.:AA00BB51

194093-42-0 | N-[(8R)-1-azabicyclo[2.2.2]oct-8-yl]-2-oxo-9-thia-5-azabicyclo[4.3.0]n ona-3,7,10-triene-3-carboxamide hydrochloride

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
99%
1 week  
$241.00   $169.00
- +
10mg
99%
1 week  
$374.00   $262.00
- +
25mg
99%
1 week  
$765.00   $535.00
- +
50mg
99%
1 week  
$1,384.00   $969.00
- +
100mg
99%
1 week  
$2,336.00   $1,635.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00BB51
Chemical Name:
N-[(8R)-1-azabicyclo[2.2.2]oct-8-yl]-2-oxo-9-thia-5-azabicyclo[4.3.0]n ona-3,7,10-triene-3-carboxamide hydrochloride
CAS Number:
194093-42-0
Molecular Formula:
C15H18ClN3O2S
Molecular Weight:
339.8403
MDL Number:
MFCD00939557
SMILES:
O=C(c1c[nH]c2c(c1=O)scc2)N[C@H]1CN2CCC1CC2.Cl
Properties
Computed Properties
 
Complexity:
499  
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
22  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
2  

Literature

Title: Inotropic effects of prokinetic agents with 5-HT(4) receptor agonist actions on human isolated myocardial trabeculae.

Journal: Life sciences 20120409

Title: Effects of the novel 5-HT3 agonist MKC-733 on the rat, mouse and guinea pig digestive tract.

Journal: Pharmacology 20080101

Title: Drug evaluation: Pumosetrag for the treatment of irritable bowel syndrome and gastroesophageal reflux disease.

Journal: Current opinion in investigational drugs (London, England : 2000) 20070501

Title: Effect of MKC-733, a 5-HT receptor partial agonist, on bowel motility and symptoms in subjects with constipation: an exploratory study.

Journal: Journal of clinical pharmacy and therapeutics 20051201

Title: Effect of a novel 5-HT3 receptor agonist MKC-733 on upper gastrointestinal motility in humans.

Journal: Alimentary pharmacology & therapeutics 20031115

Title: Chetty N, et al. Effects of the novel 5-HT3 agonist MKC-733 on the rat, mouse and guinea pig digestive tract. Pharmacology. 2008;81(2):104-9. Epub 2007 Oct 19.

Title: Coleman NS, et al. Effect of a novel 5-HT3 receptor agonist MKC-733 on upper gastrointestinal motility in humans. Aliment Pharmacol Ther. 2003 Nov 15;18(10):1039-48.

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Tags:194093-42-0 Molecular Formula|194093-42-0 MDL|194093-42-0 SMILES|194093-42-0 N-[(8R)-1-azabicyclo[2.2.2]oct-8-yl]-2-oxo-9-thia-5-azabicyclo[4.3.0]n ona-3,7,10-triene-3-carboxamide hydrochloride