[1]Melton;Henze[JournaloftheAmericanChemicalSociety,1947,vol.69,p.2018]
[1]Melton;Henze[JournaloftheAmericanChemicalSociety,1947,vol.69,p.2018]
[1]Nitzetal.[Arzneimittel-Forschung/DrugResearch,1955,vol.5,p.357,358]
[1]Moustafa;El-Emam;Subbagh;SharafEl-Din[Arzneimittel-Forschung/DrugResearch,1990,vol.40,#10,p.1076-1078]
[1]Eto;Noda;Minemoto;Noda[ChemicalandPharmaceuticalBulletin,1988,vol.36,#1,p.456-458]
[2]Kasuya;Mamada;Baba;Matsukura[JournalofPharmaceuticalSciences,1985,vol.74,#5,p.503-507]
Title: [Effect of high altitude hypoxia on the activity and protein expression of CYP2C9 and CYP2C19].
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