20449-79-0,MFCD00718095
Catalog No.:AA00BDR3

20449-79-0 | Melittin (honeybee)

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥ 98% (HPLC)
in stock  
$245.00   $171.00
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5mg
≥ 98% (HPLC)
in stock  
$682.00   $477.00
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  • Technical Information
  • Properties
  • Literature
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Technical Information
Catalog Number:
AA00BDR3
Chemical Name:
Melittin (honeybee)
CAS Number:
20449-79-0
Molecular Formula:
C131H229N39O31
Molecular Weight:
2846.4627
MDL Number:
MFCD00718095
SMILES:
NCCCCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NCC(=O)NC(C(=O)N1CCCC1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N)CCC(=O)N)CCC(=O)N)CCCNC(=N)N)CCCCN)CCCNC(=N)N)CCCCN)C(CC)C)Cc1c[nH]c2c1cccc2)CO)C(CC)C)CC(C)C)C)CC(C)C)C(O)C)C(O)C)CC(C)C)C(C)C)NC(=O)C(NC(=O)C(C(C)C)NC(=O)C(NC(=O)CNC(=O)C(C(CC)C)NC(=O)CN)C)CC(C)C
Properties
Computed Properties
 
Complexity:
6300  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
28  
Heavy Atom Count:
201  
Hydrogen Bond Acceptor Count:
37  
Hydrogen Bond Donor Count:
41  
Rotatable Bond Count:
99  
XLogP3:
-2.7  

Literature

Title: Melittin induces PTCH1 expression by down-regulating MeCP2 in human hepatocellular carcinoma SMMC-7721 cells.

Journal: Toxicology and applied pharmacology 20151001

Title: Activation of tetrodotoxin-resistant sodium channel NaV1.9 in rat primary sensory neurons contributes to melittin-induced pain behavior.

Journal: Neuromolecular medicine 20130301

Title: Cytolytic nanoparticles attenuate HIV-1 infectivity.

Journal: Antiviral therapy 20130101

Title: Binding and reorientation of melittin in a POPC bilayer: computer simulations.

Journal: Biochimica et biophysica acta 20121201

Title: Melittin suppresses VEGF-A-induced tumor growth by blocking VEGFR-2 and the COX-2-mediated MAPK signaling pathway.

Journal: Journal of natural products 20121126

Title: Melittin has an inhibitory effect on TNF-α-induced migration of human aortic smooth muscle cells by blocking the MMP-9 expression.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20121101

Title: Honey bee (Apis mellifera) venom induces AIM2 inflammasome activation in human keratinocytes.

Journal: Allergy 20121101

Title: Involvement of peripheral NMDA receptor in melittin-induced thermographic flare.

Journal: Neurochemical research 20121001

Title: Spectroscopic and computational study of melittin, cecropin A, and the hybrid peptide CM15.

Journal: The journal of physical chemistry. B 20120906

Title: Melittin initiates dopamine transporter internalization and recycling in transfected HEK-293 cells.

Journal: European journal of pharmacology 20120905

Title: Evaluation of molecularity of rate-limiting step of pore formation by antimicrobial peptides studied using mitochondria as a biosensor.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20120901

Title: Protein flexibility is key to cisplatin crosslinking in calmodulin.

Journal: Protein science : a publication of the Protein Society 20120901

Title: Aminoarabinose is essential for lipopolysaccharide export and intrinsic antimicrobial peptide resistance in Burkholderia cenocepacia(†).

Journal: Molecular microbiology 20120901

Title: Molecular response and cooperative behavior during the interactions of melittin with a membrane: dissipative quartz crystal microbalance experiments and simulations.

Journal: The journal of physical chemistry. B 20120809

Title: Gain-of-function analogues of the pore-forming peptide melittin selected by orthogonal high-throughput screening.

Journal: Journal of the American Chemical Society 20120801

Title: Anticancer peptide NK-2 targets cell surface sulphated glycans rather than sialic acids.

Journal: Biological chemistry 20120801

Title: The innate reactivity of a membrane associated peptide towards lipids: acyl transfer to melittin without enzyme catalysis.

Journal: Organic & biomolecular chemistry 20120728

Title: Melittin modulates keratinocyte function through P2 receptor-dependent ADAM activation.

Journal: The Journal of biological chemistry 20120706

Title: NMR studies on the monomer-tetramer transition of melittin in an aqueous solution at high and low temperatures.

Journal: European biophysics journal : EBJ 20120701

Title: Reaction of singlet oxygen with tryptophan in proteins: a pronounced effect of the local environment on the reaction rate.

Journal: Journal of the American Chemical Society 20120613

Title: Effects of sweet bee venom pharmacopuncture treatment for chemotherapy-induced peripheral neuropathy: a case series.

Journal: Integrative cancer therapies 20120601

Title: Novel short AMP: design and activity study.

Journal: Protein and peptide letters 20120601

Title: In vitro activities of antimicrobial cationic peptides; melittin and nisin, alone or in combination with antibiotics against Gram-positive bacteria.

Journal: Journal of chemotherapy (Florence, Italy) 20120601

Title: In situ imaging of honeybee (Apis mellifera) venom components from aqueous and aluminum hydroxide-adsorbed venom immunotherapy preparations.

Journal: The Journal of allergy and clinical immunology 20120501

Title: Charge distribution and imperfect amphipathicity affect pore formation by antimicrobial peptides.

Journal: Biochimica et biophysica acta 20120501

Title: The dynamics of melittin-induced membrane permeability.

Journal: European biophysics journal : EBJ 20120501

Title: In vitro activity of several antimicrobial peptides against colistin-susceptible and colistin-resistant Acinetobacter baumannii.

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20120401

Title: Truncated peptides from melittin and its analog with high lytic activity at endosomal pH enhance branched polyethylenimine-mediated gene transfection.

Journal: The journal of gene medicine 20120401

Title: Effects of a non-selective TRPC channel blocker, SKF-96365, on melittin-induced spontaneous persistent nociception and inflammatory pain hypersensitivity.

Journal: Neuroscience bulletin 20120401

Title: Difference between magainin-2 and melittin assemblies in phosphatidylcholine bilayers: results from coarse-grained simulations.

Journal: The journal of physical chemistry. B 20120308

Title: Production of human antibody fragments binding to melittin and phospholipase A2 in Africanised bee venom: minimising venom toxicity.

Journal: Basic & clinical pharmacology & toxicology 20120301

Title: Trivalent ultrashort lipopeptides are potent pH dependent antifungal agents.

Journal: Journal of medicinal chemistry 20120209

Title: Combined electron transfer dissociation-collision-induced dissociation fragmentation in the mass spectrometric distinction of leucine, isoleucine, and hydroxyproline residues in Peptide natural products.

Journal: Journal of proteome research 20120203

Title: Consequences of alteration in leucine zipper sequence of melittin in its neutralization of lipopolysaccharide-induced proinflammatory response in macrophage cells and interaction with lipopolysaccharide.

Journal: The Journal of biological chemistry 20120113

Title: Investigation of model membrane disruption mechanism by melittin using pulse electron paramagnetic resonance spectroscopy and cryogenic transmission electron microscopy.

Journal: The journal of physical chemistry. B 20120112

Title: Characterization of in vitro hemostatic peptide effects by thromboelastography.

Journal: Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20120101

Title: Protective effect of melittin on inflammation and apoptosis in acute liver failure.

Journal: Apoptosis : an international journal on programmed cell death 20120101

Title: Anti-cancer effect of bee venom toxin and melittin in ovarian cancer cells through induction of death receptors and inhibition of JAK2/STAT3 pathway.

Journal: Toxicology and applied pharmacology 20120101

Title: Episodic hemorrhage during honeybee venom anaphylaxis: potential mechanisms.

Journal: Journal of investigational allergology & clinical immunology 20120101

Title: The mediation of the central histaminergic system in the pressor effect of intracerebroventricularly injected melittin, a phospholipase A2 activator, in normotensive rats.

Journal: Prostaglandins, leukotrienes, and essential fatty acids 20120101

Title: Respiratory syncytial virus reverses airway hyperresponsiveness to methacholine in ovalbumin-sensitized mice.

Journal: PloS one 20120101

Title: Interaction of melittin peptides with perfluorocarbon nanoemulsion particles.

Journal: The journal of physical chemistry. B 20111229

Title: PEG-stabilized lipid disks as carriers for amphiphilic antimicrobial peptides.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20111220

Title: Melittin inhibits cerulein-induced acute pancreatitis via inhibition of the JNK pathway.

Journal: International immunopharmacology 20111201

Title: NMR studies on thermal stability of α-helix conformation of melittin in pure ethanol and ethanol-water mixture solvents.

Journal: Journal of peptide science : an official publication of the European Peptide Society 20111201

Title: Melittin adsorption and lipid monolayer disruption at liquid-liquid interfaces.

Journal: Langmuir : the ACS journal of surfaces and colloids 20111115

Title: Clinical efficacy of a specifically targeted antimicrobial peptide mouth rinse: targeted elimination of Streptococcus mutans and prevention of demineralization.

Journal: Caries research 20111101

Title: Melittin attenuates liver injury in thioacetamide-treated mice through modulating inflammation and fibrogenesis.

Journal: Experimental biology and medicine (Maywood, N.J.) 20111101

Title: The structure, molecular dynamics, and energetics of centrin-melittin complex.

Journal: Proteins 20111101

Title: Protective effects of melittin on transforming growth factor-β1 injury to hepatocytes via anti-apoptotic mechanism.

Journal: Toxicology and applied pharmacology 20111015

Title: Analysis of the role of Mg²⁺ on conformational change and target recognition by ciliate Euplotes octocarinatus centrin.

Journal: Journal of photochemistry and photobiology. B, Biology 20111005

Title: Melittin enhances apoptosis through suppression of IL-6/sIL-6R complex-induced NF-κB and STAT3 activation and Bcl-2 expression for human fibroblast-like synoviocytes in rheumatoid arthritis.

Journal: Joint, bone, spine : revue du rhumatisme 20111001

Title: Evidence for α-helices in the gas phase: a case study using Melittin from honey bee venom.

Journal: The Analyst 20110907

Title: An impedance QCM study on the partitioning of bioactive compounds in supported phospholipid bilayers.

Journal: Colloids and surfaces. B, Biointerfaces 20110901

Title: Influence of the arrangement and secondary structure of melittin peptides on the formation and stability of toroidal pores.

Journal: Biochimica et biophysica acta 20110901

Title: Myosins and DYNLL1/LC8 in the honey bee (Apis mellifera L.) brain.

Journal: Journal of insect physiology 20110901

Title: Penetration of antibody-opsonized cells by the membrane attack complex of complement promotes Ca(2+) influx and induces streamers.

Journal: European journal of immunology 20110801

Title: High content analysis to determine cytotoxicity of the antimicrobial peptide, melittin and selected structural analogs.

Journal: Peptides 20110801

Title: Membrane cholesterol modulates the cytolytic mechanism of myotoxin II, a Lys49 phospholipase A2 homologue from the venom of Bothrops asper.

Journal: Cell biochemistry and function 20110701

Title: Acetylcholine and norepinephrine mediate GABAergic but not glycinergic transmission enhancement by melittin in adult rat substantia gelatinosa neurons.

Journal: Journal of neurophysiology 20110701

Title: Tat peptide-calmodulin binding studies and bioinformatics of HIV-1 protein-calmodulin interactions.

Journal: Proteins 20110701

Title: Glucose interactions with a model peptide.

Journal: Proteins 20110701

Title: W-Band pulse EPR distance measurements in peptides using Gd(3+)-dipicolinic acid derivatives as spin labels.

Journal: Physical chemistry chemical physics : PCCP 20110614

Title: Anti-cancer effect of bee venom in prostate cancer cells through activation of caspase pathway via inactivation of NF-κB.

Journal: The Prostate 20110601

Title: Effects of SKF-96365, a TRPC inhibitor, on melittin-induced inward current and intracellular Ca2+ rise in primary sensory cells.

Journal: Neuroscience bulletin 20110601

Title: Online monitoring of metabolism and morphology of peptide-treated neuroblastoma cancer cells and keratinocytes.

Journal: Journal of bioenergetics and biomembranes 20110601

Title: Gangliosides inhibit bee venom melittin cytotoxicity but not phospholipase A(2)-induced degranulation in mast cells.

Journal: Toxicology and applied pharmacology 20110501

Title: Melittin liposomes surface modified with poloxamer 188: in vitro characterization and in vivo evaluation.

Journal: Die Pharmazie 20110501

Title: Melittin activates TRPV1 receptors in primary nociceptive sensory neurons via the phospholipase A2 cascade pathways.

Journal: Biochemical and biophysical research communications 20110429

Title: Electron detachment dissociation for top-down mass spectrometry of acidic proteins.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20110411

Title: Expression and functional characterization of a recombinant targeted toxin with an uPA cleavable linker in Pichia pastoris.

Journal: Protein expression and purification 20110401

Title: Quantification of protein-protein interactions with chemical cross-linking and mass spectrometry.

Journal: Journal of proteome research 20110401

Title: Effects induced by Apis mellifera venom and its components in experimental models of nociceptive and inflammatory pain.

Journal: Toxicon : official journal of the International Society on Toxinology 20110401

Title: Oligopeptidase B from Serratia proteamaculans. II. Enzymatic characteristics: substrate analysis, influence of calcium ions, pH and temperature dependences.

Journal: Biochemistry. Biokhimiia 20110401

Title: Structural dynamics of a lytic peptide interacting with a supported lipid bilayer.

Journal: Biophysical journal 20110302

Title: Helix conformation of a small peptide melittin in a methanol-water mixed solvent studied by NMR.

Journal: Protein and peptide letters 20110301

Title: Acyl transfer from phosphocholine lipids to melittin.

Journal: Chemical communications (Cambridge, England) 20110207

Title: Ultrastructural observation on sterilization of melittin.

Journal: Science China. Life sciences 20110201

Title: Characterization of honeybee venom by MALDI-TOF and nanoESI-QqTOF mass spectrometry.

Journal: Journal of pharmaceutical and biomedical analysis 20110125

Title: Melittin stimulates fatty acid release through non-phospholipase-mediated mechanisms and interacts with the dopamine transporter and other membrane-spanning proteins.

Journal: European journal of pharmacology 20110115

Title: Monitoring membrane binding and insertion of peptides by two-color fluorescent label.

Journal: Biochimica et biophysica acta 20110101

Title: Tryptophan orientations in membrane-bound gramicidin and melittin-a comparative linear dichroism study on transmembrane and surface-bound peptides.

Journal: Biochimica et biophysica acta 20110101

Title: Multifunctional CPP polymer system for tumor-targeted pDNA and siRNA delivery.

Journal: Methods in molecular biology (Clifton, N.J.) 20110101

Title: Membrane partitioning: 'classical' and 'nonclassical' hydrophobic effects.

Journal: The Journal of membrane biology 20110101

Title: The role of electrostatic interactions in the membrane binding of melittin.

Journal: Journal of molecular recognition : JMR 20110101

Title: Melittin restores proteasome function in an animal model of ALS.

Journal: Journal of neuroinflammation 20110101

Title: Melittin inhibits atherosclerosis in LPS/high-fat treated mice through atheroprotective actions.

Journal: Journal of atherosclerosis and thrombosis 20110101

Title: Construction and characterization of an anti-asialoglycoprotein receptor single-chain variable-fragment-targeted melittin.

Journal: Biotechnology and applied biochemistry 20110101

Title: Magnetic 'fishing' assay to screen small-molecule mixtures for modulators of protein-protein interactions.

Journal: Analytical chemistry 20101201

Title: Melittin promotes exocytosis in neuroendocrine cells through the activation of phospholipase A₂.

Journal: Regulatory peptides 20101130

Title: Acute physiopathological effects of honeybee (Apis mellifera) envenoming by subcutaneous route in a mouse model.

Journal: Toxicon : official journal of the International Society on Toxinology 20101101

Title: The synergistic action of melittin and phospholipase A2 with lipid membranes: development of linear dichroism for membrane-insertion kinetics.

Journal: Protein and peptide letters 20101101

Title: A gigaseal obtained with a self-assembled long-lifetime lipid bilayer on a single polyelectrolyte multilayer-filled nanopore.

Journal: ACS nano 20100928

Title: Quantification of melittin and apamin in bee venom lyophilized powder from Apis mellifera by liquid chromatography-diode array detector-tandem mass spectrometry.

Journal: Analytical biochemistry 20100915

Title: Cell-selective lysis by novel analogues of melittin against human red blood cells and Escherichia coli.

Journal: Biochemistry 20100914

Title: Antibiotic and synergistic effect of Leu-Lys rich peptide against antibiotic resistant microorganisms isolated from patients with cholelithiasis.

Journal: Biochemical and biophysical research communications 20100903

Title: Africanized honey bee (Apis mellifera) venom profiling: Seasonal variation of melittin and phospholipase A(2) levels.

Journal: Toxicon : official journal of the International Society on Toxinology 20100901

Title: Characterization of perfluorooctylbromide-based nanoemulsion particles using atomistic molecular dynamics simulations.

Journal: The journal of physical chemistry. B 20100812

Title: Antimicrobial peptides bind more strongly to membrane pores.

Journal: Biochimica et biophysica acta 20100801

Title: Trypanosoma cruzi: synergistic cytotoxicity of multiple amphipathic anti-microbial peptides to T. cruzi and potential bacterial hosts.

Journal: Experimental parasitology 20100801

Title: Antimicrobial peptides in toroidal and cylindrical pores.

Journal: Biochimica et biophysica acta 20100801

Title: Identification of a novel melittin isoform from Africanized Apis mellifera venom.

Journal: Peptides 20100801

Title: Topology and dynamics of melittin within the liposome revealed by a combination of mass spectrometry and chemical modification.

Journal: Biochemical and biophysical research communications 20100618

Title: An OEGylated thiol monolayer for the tethering of liposomes and the study of liposome interactions.

Journal: Talanta 20100615

Title: A unique protein labeling system based on melittin and the non-covalent binding-induced pyrene excimer.

Journal: Chemical communications (Cambridge, England) 20100607

Title: A metal-supported biomimetic micromembrane allowing the recording of single-channel activity and of impedance spectra of membrane proteins.

Journal: Bioelectrochemistry (Amsterdam, Netherlands) 20100601

Title: Effect of α-helical peptides on liposome structure: a comparative study of melittin and alamethicin.

Journal: Journal of colloid and interface science 20100601

Title: Recognition, neutralization, and clearance of target peptides in the bloodstream of living mice by molecularly imprinted polymer nanoparticles: a plastic antibody.

Journal: Journal of the American Chemical Society 20100519

Title: Selective death of human breast cancer cells by lytic immunoliposomes: Correlation with their HER2 expression level.

Journal: Cancer letters 20100428

Title: Calcium-induced structural transitions of the calmodulin-melittin system studied by electrospray mass spectrometry: conformational subpopulations and metal-unsaturated intermediates.

Journal: Biochemistry 20100427

Title: Inhibition of Escherichia coli ATP synthase by amphibian antimicrobial peptides.

Journal: International journal of biological macromolecules 20100401

Title: Melittin induces apoptotic features in Candida albicans.

Journal: Biochemical and biophysical research communications 20100326

Title: Impact of amino acid replacements on in vitro permeation enhancement and cytotoxicity of the intestinal absorption promoter, melittin.

Journal: International journal of pharmaceutics 20100315

Title: IL-4 induces protection of vascular endothelial cells against killing by complement and melittin through lipid biosynthesis.

Journal: European journal of immunology 20100301

Title: Design, synthesis and antimicrobial properties of non-hemolytic cationic alpha-cyclopeptoids.

Journal: Bioorganic & medicinal chemistry 20100301

Title: Melittin suppresses PMA-induced tumor cell invasion by inhibiting NF-kappaB and AP-1-dependent MMP-9 expression.

Journal: Molecules and cells 20100227

Title: Bee venom suppresses PMA-mediated MMP-9 gene activation via JNK/p38 and NF-kappaB-dependent mechanisms.

Journal: Journal of ethnopharmacology 20100217

Title: Micelle-bound structures and dynamics of the hinge deleted analog of melittin and its diastereomer: implications in cell selective lysis by D-amino acid containing antimicrobial peptides.

Journal: Biochimica et biophysica acta 20100201

Title: Real-time monitoring of melittin-induced pore and tubule formation from supported lipid bilayers and its physiological relevance.

Journal: Chemistry and physics of lipids 20100201

Title: Dissociation of calmodulin-target peptide complexes by the lipid mediator sphingosylphosphorylcholine: implications in calcium signaling.

Journal: The Journal of biological chemistry 20100115

Title: The effect of calcium ions and peptide ligands on the relative stabilities of the calmodulin dumbbell and compact structures.

Journal: The journal of physical chemistry. B 20100114

Title: Vesicle budding induced by a pore-forming peptide.

Journal: Journal of the American Chemical Society 20100113

Title: Synthesis and in vitro testing of new potent polyacridine-melittin gene delivery peptides.

Journal: Bioconjugate chemistry 20100101

Title: [Comparative studies of structural properties of melittin in water and trifluroethanol/water mixture by the molecular dynamics method].

Journal: Biofizika 20100101

Title: Surface plasmon resonance spectroscopy for studying the membrane binding of antimicrobial peptides.

Journal: Methods in molecular biology (Clifton, N.J.) 20100101

Title: The anti-arthritic effects of synthetic melittin on the complete Freund's adjuvant-induced rheumatoid arthritis model in rats.

Journal: The American journal of Chinese medicine 20100101

Title: Secretory expression of porcine interferon-gamma in baculovirus using HBM signal peptide and its inhibition activity on the replication of porcine reproductive and respiratory syndrome virus.

Journal: Veterinary immunology and immunopathology 20091215

Title: Melittin-regenerated purple membrane.

Journal: Biochemistry. Biokhimiia 20091201

Title: Evaluation of intestinal absorption and mucosal toxicity using two promoters. II. Rat instillation and perfusion studies.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20091105

Title: Evaluation of intestinal absorption enhancement and local mucosal toxicity of two promoters. I. Studies in isolated rat and human colonic mucosae.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20091105

Title: Hydrogen bonding and solvent polarity markers in the uv resonance raman spectrum of tryptophan: application to membrane proteins.

Journal: The journal of physical chemistry. B 20091105

Title: Interactions of 2,2,2-trifluoroethanol with melittin.

Journal: Magnetic resonance in chemistry : MRC 20091101

Title: Assessment of the multiphase interaction between a membrane disrupting peptide and a lipid membrane.

Journal: The journal of physical chemistry. B 20091029

Title: Cause and effect of melittin-induced pore formation: a computational approach.

Journal: Langmuir : the ACS journal of surfaces and colloids 20091020

Title: Formation of individual protein channels in lipid bilayers suspended in nanopores.

Journal: Colloids and surfaces. B, Biointerfaces 20091015

Title: Phospholipid flip-flop modulated by transmembrane peptides WALP and melittin.

Journal: Journal of structural biology 20091001

Title: In vitro- and in vivo-targeted tumor lysis by an MMP2 cleavable melittin-LAP fusion protein.

Journal: International journal of oncology 20091001

Title: Molecularly targeted nanocarriers deliver the cytolytic peptide melittin specifically to tumor cells in mice, reducing tumor growth.

Journal: The Journal of clinical investigation 20090901

Title: Postantibiotic effect of purified melittin from honeybee (Apis mellifera) venom against Escherichia coli and Staphylococcus aureus.

Journal: Journal of Asian natural products research 20090901

Title: Activation of ERK1/2 in the primary injury site is required to maintain melittin-enhanced wind-up of rat spinal wide-dynamic-range neurons.

Journal: Neuroscience letters 20090814

Title: Design of high payload PLGA nanoparticles containing melittin/sodium dodecyl sulfate complex by the hydrophobic ion-pairing technique.

Journal: Drug development and industrial pharmacy 20090801

Title: The RH 421 styryl dye induced, pore model-dependent modulation of antimicrobial peptides activity in reconstituted planar membranes.

Journal: Biochimica et biophysica acta 20090801

Title: Ventral cochlear nucleus responses to contralateral sound are mediated by commissural and olivocochlear pathways.

Journal: Journal of neurophysiology 20090801

Title: Simultaneous collision induced dissociation of the charge reduced parent ion during electron capture dissociation.

Journal: Analytical chemistry 20090801

Title: [Cloning and expression of a gene encoding shortened LfcinB(1-15)-Melittin(5-12) hybrid peptide in Escherichia coli BL21(DE3)].

Journal: Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20090701

Title: Hecate-CGbeta conjugate and gonadotropin suppression shows two distinct mechanisms of action in the treatment of adrenocortical tumors in transgenic mice expressing Simian Virus 40 T antigen under inhibin-alpha promoter.

Journal: Endocrine-related cancer 20090601

Title: Evidence for a Ca(2+)-specific conformational change in avian thymic hormone, a high-affinity beta-parvalbumin.

Journal: Biochemistry 20090512

Title: Surfactant protein-D regulates the postnatal maturation of pulmonary surfactant lipid pool sizes.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20090501

Title: Targeting the cancer stroma with a fibroblast activation protein-activated promelittin protoxin.

Journal: Molecular cancer therapeutics 20090501

Title: Free energies of molecular bound states in lipid bilayers: lethal concentrations of antimicrobial peptides.

Journal: Biophysical journal 20090422

Title: Thermodynamics of melittin binding to lipid bilayers. Aggregation and pore formation.

Journal: Biochemistry 20090331

Title: Specificity of ion-protein interactions: complementary and competitive effects of tetrapropylammonium, guanidinium, sulfate, and chloride ions.

Journal: The journal of physical chemistry. B 20090312

Title: Melittin, a major component of bee venom, sensitizes human hepatocellular carcinoma cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis by activating CaMKII-TAK1-JNK/p38 and inhibiting IkappaBalpha kinase-NFkappaB.

Journal: The Journal of biological chemistry 20090206

Title: Synthesis and biological evaluation of a bioresponsive and endosomolytic siRNA-polymer conjugate.

Journal: Molecular pharmaceutics 20090101

Title: Cardiovascular effect of peripheral injected melittin in normotensive conscious rats: Mediation of the central cholinergic system.

Journal: Prostaglandins, leukotrienes, and essential fatty acids 20090101

Title: Engineering stabilized vascular endothelial growth factor-A antagonists: synthesis, structural characterization, and bioactivity of grafted analogues of cyclotides.

Journal: Journal of medicinal chemistry 20081225

Title: On the mechanism of pore formation by melittin.

Journal: The Journal of biological chemistry 20081205

Title: A novel cationic-peptide coating for the prevention of microbial colonization on contact lenses.

Journal: Journal of applied microbiology 20081201

Title: Label-free measurements of molecular transport across liposome membranes using evanescent-wave sensing.

Journal: Chemphyschem : a European journal of chemical physics and physical chemistry 20081201

Title: Extracellular signal-regulated kinases mediate melittin-induced hypersensitivity of spinal neurons to chemical and thermal but not mechanical stimuli.

Journal: Brain research bulletin 20081125

Title: Monitoring orientation and dynamics of membrane-bound melittin utilizing dansyl fluorescence.

Journal: The journal of physical chemistry. B 20081106

Title: Melittin-lipid bilayer interactions and the role of cholesterol.

Journal: Biophysical journal 20081101

Title: The lipid composition determines the kinetics of adhesion and spreading of liposomes on mercury electrodes.

Journal: Bioelectrochemistry (Amsterdam, Netherlands) 20081101

Title: Roles of peripheral P2X and P2Y receptors in the development of melittin-induced nociception and hypersensitivity.

Journal: Neurochemical research 20081001

Title: Probing the steric barrier of nonionic surfactant vesicles with melittin.

Journal: Biochimica et biophysica acta 20081001

Title: Melittin-lipid interaction: a comparative study using liposomes, micelles and bilayer disks.

Journal: Biochimica et biophysica acta 20081001

Title: Influence of antimicrobial peptides on the formation of nonlamellar lipid mesophases.

Journal: Biochimica et biophysica acta 20081001

Title: Toroidal pores formed by antimicrobial peptides show significant disorder.

Journal: Biochimica et biophysica acta 20081001

Title: Dual-color fluorescence-burst analysis to study pore formation and protein-protein interactions.

Journal: Methods (San Diego, Calif.) 20081001

Title: Characterization of melittin binding to Euplotes octocarinatus centrin.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20080901

Title: Honeybee venom induces calcium-dependent but caspase-independent apoptotic cell death in human melanoma A2058 cells.

Journal: Toxicon : official journal of the International Society on Toxinology 20080801

Title: Interdomain cooperativity of calmodulin bound to melittin preferentially increases calcium affinity of sites I and II.

Journal: Proteins 20080601

Title: Melittin prevents liver cancer cell metastasis through inhibition of the Rac1-dependent pathway.

Journal: Hepatology (Baltimore, Md.) 20080601

Title: Targeted therapy for adrenocortical tumors in transgenic mice through their LH receptor by Hecate-human chorionic gonadotropin beta conjugate.

Journal: Endocrine-related cancer 20080601

Title: Pleurocidin-derived antifungal peptides with selective membrane-disruption effect.

Journal: Biochemical and biophysical research communications 20080509

Title: Crystallization and preliminary X-ray characterization of full-length Chlamydomonas reinhardtii centrin.

Journal: Acta crystallographica. Section F, Structural biology and crystallization communications 20080501

Title: Melittin-induced [Ca2+]i increases and subsequent death in canine renal tubular cells.

Journal: Human & experimental toxicology 20080501

Title: Roles of peripheral mitogen-activated protein kinases in melittin-induced nociception and hyperalgesia.

Journal: Neuroscience 20080409

Title: Cationic peptide-induced remodelling of model membranes: direct visualization by in situ atomic force microscopy.

Journal: Journal of structural biology 20080401

Title: Inhibition of the ATPase activity of the catalytic portion of ATP synthases by cationic amphiphiles.

Journal: Biochimica et biophysica acta 20080401

Title: Synthesis and characterization of stable fluorocarbon nanostructures as drug delivery vehicles for cytolytic peptides.

Journal: Nano letters 20080401

Title: Label-free detection of melittin binding to a membrane using electrochemical-localized surface plasmon resonance.

Journal: Analytical chemistry 20080315

Title: Probing melittin helix-coil equilibria in solutions and vesicles.

Journal: The journal of physical chemistry. B 20080313

Title: Melittin interaction with sulfated cell surface sugars.

Journal: Biochemistry 20080304

Title: Melittin exhibits necrotic cytotoxicity in gastrointestinal cells which is attenuated by cholesterol.

Journal: Biochemical pharmacology 20080301

Title: Phospholipase A2 activation enhances inhibitory synaptic transmission in rat substantia gelatinosa neurons.

Journal: Journal of neurophysiology 20080301

Title: Surface-induced dissociation of peptides and protein complexes in a quadrupole/time-of-flight mass spectrometer.

Journal: Analytical chemistry 20080301

Title: Membrane-proximal cytoplasmic domain of Moloney murine leukemia virus envelope tail facilitates fusion.

Journal: Experimental and molecular pathology 20080201

Title: Melittin induces Bcl-2 and caspase-3-dependent apoptosis through downregulation of Akt phosphorylation in human leukemic U937 cells.

Journal: Toxicon : official journal of the International Society on Toxinology 20080101

Title: Amphipathic alpha-helical peptide, HP (2-20), and its analogues derived from Helicobacter pylori: pore formation mechanism in various lipid compositions.

Journal: Biochimica et biophysica acta 20080101

Title: Effects of melittin on the production of matrix metalloproteinase-1 and -3 in rheumatoid arthritic fibroblast-like synoviocytes.

Journal: Journal of pharmacological sciences 20080101

Title: [Isolation and properties of cysteine protease from Serratia proteamaculans 94].

Journal: Bioorganicheskaia khimiia 20080101

Title: Comprehensive characterization of molecular interactions based on nanomechanics.

Journal: PloS one 20080101

Title: Structural and thermodynamic analyses of the interaction between melittin and lipopolysaccharide.

Journal: Biochimica et biophysica acta 20071201

Title: Cardiovascular effects of centrally injected melittin in hemorrhaged hypotensive rats: the investigation of peripheral mechanisms.

Journal: Neuropeptides 20071201

Title: [Effects of melittin on growth and angiogenesis of human hepatocellular carcinoma BEL-7402 cell xenografts in nude mice].

Journal: Ai zheng = Aizheng = Chinese journal of cancer 20071201

Title: [Enhancing transfection efficiency of polyethylenimine by a hydrophobic peptide from bee venom].

Journal: Zhongguo shi yan xue ye xue za zhi 20071201

Title: Cell selectivity of an antimicrobial peptide melittin diastereomer with D-amino acid in the leucine zipper sequence.

Journal: Journal of biochemistry and molecular biology 20071130

Title: Design and synthesis of novel antibacterial peptide-resin conjugates.

Journal: Bioorganic & medicinal chemistry letters 20071101

Title: Spectrally and time-resolved fluorescence spectroscopic study on melittin-calmodulin interaction.

Journal: Journal of biochemistry 20071101

Title: [Melittin inhibits proliferation and induces apoptosis of malignant human glioma cells].

Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20071101

Title: [Preparation and in vitro tumor cells selectivity of sterically stabilized immunoliposomal peptides in bee venom].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20071101

Title: Application of principal component analysis in protein unfolding: an all-atom molecular dynamics simulation study.

Journal: The Journal of chemical physics 20071028

Title: Melittin: a membrane-active peptide with diverse functions.

Journal: Bioscience reports 20071001

Title: Evidence that the genes encoding the melittin-related peptides in the skins of the Japanese frogs Rana sakuraii and Rana tagoi are not orthologous to bee venom melittin genes: developmental- and tissue-dependent gene expression.

Journal: Peptides 20071001

Title: A dimethylmaleic acid-melittin-polylysine conjugate with reduced toxicity, pH-triggered endosomolytic activity and enhanced gene transfer potential.

Journal: The journal of gene medicine 20070901

Title: [Effects of melittin on expressions of mitochondria membrane protein 7A6, cell apoptosis-related gene products Fas and Fas ligand in hepatocarcinoma cells].

Journal: Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20070901

Title: Recombinant plasmid constructs expressing gene for antimicrobial peptide melittin for the therapy of Mycoplasma and chlamydia infections.

Journal: Bulletin of experimental biology and medicine 20070901

Title: Nanoscale dewetting transition in protein complex folding.

Journal: The journal of physical chemistry. B 20070802

Title: Real-time structural investigation of a lipid bilayer during its interaction with melittin using sum frequency generation vibrational spectroscopy.

Journal: Biophysical journal 20070801

Title: Therapeutic application of anti-arthritis, pain-releasing, and anti-cancer effects of bee venom and its constituent compounds.

Journal: Pharmacology & therapeutics 20070801

Title: Bee venom and melittin reduce proinflammatory mediators in lipopolysaccharide-stimulated BV2 microglia.

Journal: International immunopharmacology 20070801

Title: Exploring the effect of cholesterol in lipid bilayer membrane on the melittin penetration mechanism.

Journal: Analytical biochemistry 20070801

Title: Melittin, a major bioactive component of bee venom toxin, inhibits PDGF receptor beta-tyrosine phosphorylation and downstream intracellular signal transduction in rat aortic vascular smooth muscle cells.

Journal: Journal of toxicology and environmental health. Part A 20070801

Title: A protein whose binding to Na,K-ATPase is regulated by ouabain.

Journal: Biochemistry. Biokhimiia 20070801

Title: Hydrophobic and electrostatic forces control the retention of membrane peptides and proteins with an immobilised phosphatidic acid column.

Journal: Journal of chromatography. A 20070713

Title: Melittin as an epithelial permeability enhancer I: investigation of its mechanism of action in Caco-2 monolayers.

Journal: Pharmaceutical research 20070701

Title: Melittin as a permeability enhancer II: in vitro investigations in human mucus secreting intestinal monolayers and rat colonic mucosae.

Journal: Pharmaceutical research 20070701

Title: Effect of lipid headgroup composition on the interaction between melittin and lipid bilayers.

Journal: Journal of colloid and interface science 20070701

Title: The lipid dependence of melittin action investigated by dual-color fluorescence burst analysis.

Journal: Biophysical journal 20070701

Title: Apis mellifera venom and melittin block neither NF-kappa B-p50-DNA interactions nor the activation of NF-kappa B, instead they activate the transcription of proinflammatory genes and the release of reactive oxygen intermediates.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20070701

Title: Substitution of the leucine zipper sequence in melittin with peptoid residues affects self-association, cell selectivity, and mode of action.

Journal: Biochimica et biophysica acta 20070601

Title: Rationale for the design of shortened derivatives of the NK-lysin-derived antimicrobial peptide NK-2 with improved activity against Gram-negative pathogens.

Journal: The Journal of biological chemistry 20070518

Title: Kinetics of channel formation in bilayer lipid membranes (BLMs) and tethered BLMs: monazomycin and melittin.

Journal: Langmuir : the ACS journal of surfaces and colloids 20070508

Title: The use of solvent relaxation technique to investigate headgroup hydration and protein binding of simple and mixed phosphatidylcholine/surfactant bilayer membranes.

Journal: Biochimica et biophysica acta 20070501

Title: Inhibitory effects of melittin on the production of lipopolysaccharide-induced matrix metalloproteinase 3 in human osteoarthritic chondrocytes.

Journal: Toxicon : official journal of the International Society on Toxinology 20070501

Title: The response of giant phospholipid vesicles to pore-forming peptide melittin.

Journal: Biochimica et biophysica acta 20070501

Title: Simultaneous measurements of K+ and calcein release from liposomes and the determination of pore size formed in a membrane.

Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20070501

Title: Use of hecate-chorionic gonadotropin beta conjugate in therapy of lutenizing hormone receptor expressing gonadal somatic cell tumors.

Journal: Molecular and cellular endocrinology 20070415

Title: The involvement of the central cholinergic system in the pressor and bradycardic effects of centrally administrated melittin in normotensive conscious rats.

Journal: Neuropeptides 20070401

Title: Structural characterization of the functional regions in the archaeal protein Sso7d.

Journal: Proteins 20070401

Title: Molecular cloning of the precursor polypeptide of mastoparan B and its putative processing enzyme, dipeptidyl peptidase IV, from the black-bellied hornet, Vespa basalis.

Journal: Insect molecular biology 20070401

Title: Multiple functions of DOA1 in Candida albicans.

Journal: Microbiology (Reading, England) 20070401

Title: Alpha,beta-dehydrophenylalanine containing cecropin-melittin hybrid peptides: conformation and activity.

Journal: Journal of peptide science : an official publication of the European Peptide Society 20070401

Title: Structural and functional behavior of biologically active monomeric melittin.

Journal: Journal of molecular graphics & modelling 20070301

Title: Expression of genes encoding antimicrobial and bradykinin-related peptides in skin of the stream brown frog Rana sakuraii.

Journal: Peptides 20070301

Title: Activities of four frog skin-derived antimicrobial peptides (temporin-1DRa, temporin-1Va and the melittin-related peptides AR-23 and RV-23) against anaerobic bacteria.

Journal: International journal of antimicrobial agents 20070301

Title: Orientation and dynamics of melittin in membranes of varying composition utilizing NBD fluorescence.

Journal: Biophysical journal 20070215

Title: Multiple orientation of melittin inside a single lipid bilayer determined by combined vibrational spectroscopic studies.

Journal: Journal of the American Chemical Society 20070207

Title: Allosteric inhibition of rat neuronal nitric-oxide synthase caused by interference with the binding of calmodulin to the enzyme.

Journal: Biochimica et biophysica acta 20070201

Title: Defect formation of lytic peptides in lipid membranes and their influence on the thermodynamic properties of the pore environment.

Journal: Biochimica et biophysica acta 20070201

Title: Melittin inhibits inflammatory target gene expression and mediator generation via interaction with IkappaB kinase.

Journal: Biochemical pharmacology 20070115

Title: Phospholipase A2-independent Ca2+ entry and subsequent apoptosis induced by melittin in human MG63 osteosarcoma cells.

Journal: Life sciences 20070102

Title: The membrane-induced structure of melittin is correlated with the fluidity of the lipids.

Journal: Biochimica et biophysica acta 20070101

Title: Sub parts-per-million mass measurement accuracy of intact proteins and product ions achieved using a dual electrospray ionization quadrupole fourier transform ion cyclotron resonance mass spectrometer.

Journal: Journal of the American Society for Mass Spectrometry 20070101

Title: Quantifying the effects of melittin on liposomes.

Journal: Biochimica et biophysica acta 20070101

Title: [Interaction of melittin with ion channels of excitable membranes].

Journal: Biofizika 20070101

Title: Manipulation of charge states of biopolymer ions by atmospheric pressure ion/molecule reactions implemented in an extractive electrospray ionization source.

Journal: European journal of mass spectrometry (Chichester, England) 20070101

Title: Monitoring conformational changes in protein complexes using chemical cross-linking and Fourier transform ion cyclotron resonance mass spectrometry: the effect of calcium binding on the calmodulin-melittin complex.

Journal: European journal of mass spectrometry (Chichester, England) 20070101

Title: [The principles of analysis on multicomponent fluorescence spectra of proteins. Temperature and pH-induced transitions in tetrameric melittin].

Journal: Biofizika 20070101

Title: Roles of phospholipase A2 isoforms in swelling- and melittin-induced arachidonic acid release and taurine efflux in NIH3T3 fibroblasts.

Journal: American journal of physiology. Cell physiology 20061201

Title: DNA polyplexes based on degradable oligoethylenimine-derivatives: combination with EGF receptor targeting and endosomal release functions.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20061128

Title: Effect of ionic strength on the organization and dynamics of membrane-bound melittin.

Journal: Biophysical chemistry 20061120

Title: Diffraction-based density restraints for membrane and membrane-peptide molecular dynamics simulations.

Journal: Biophysical journal 20061115

Title: [Expression of melittin tagged with green fluorescent protein and its use in hepatocellular carcinoma treatment].

Journal: Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20061101

Title: Effect of ionic strength on folding and aggregation of the hemolytic peptide melittin in solution.

Journal: Biopolymers 20061005

Title: Femtosecond studies of tryptophan fluorescence dynamics in proteins: local solvation and electronic quenching.

Journal: The journal of physical chemistry. B 20060921

Title: Ca2+-independent phospholipase A2 enhances store-operated Ca2+ entry in dystrophic skeletal muscle fibers.

Journal: Journal of cell science 20060915

Title: Ion/molecule reactions of cation radicals formed from protonated polypeptides via gas-phase ion/ion electron transfer.

Journal: Journal of the American Chemical Society 20060913

Title: Growth arrest and apoptosis of the human hepatocellular carcinoma cell line BEL-7402 induced by melittin.

Journal: Onkologie 20060901

Title: Electrochemical investigation of melittin reconstituted into a mercury-supported lipid bilayer.

Journal: Langmuir : the ACS journal of surfaces and colloids 20060718

Title: Solid-state NMR investigation of the membrane-disrupting mechanism of antimicrobial peptides MSI-78 and MSI-594 derived from magainin 2 and melittin.

Journal: Biophysical journal 20060701

Title: Alpha-helix formation in melittin and beta-lactoglobulin A induced by fluorinated dialcohols.

Journal: The journal of physical chemistry. B 20060608

Title: The role of the central thromboxane A2 in cardiovascular effects of a phospholipase A2 activator melittin administrated intracerebroventricularly in normotensive conscious rats.

Journal: Neuropeptides 20060601

Title: Peptide conformation in gas phase probed by collision-induced dissociation and its correlation to conformation in condensed phases.

Journal: Journal of the American Society for Mass Spectrometry 20060601

Title: The effect of acteoside on histamine release and arachidonic acid release in RBL-2H3 mast cells.

Journal: Archives of pharmacal research 20060601

Title: Melittin analogs with high lytic activity at endosomal pH enhance transfection with purified targeted PEI polyplexes.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20060515

Title: Melittin inhibits vascular smooth muscle cell proliferation through induction of apoptosis via suppression of nuclear factor-kappaB and Akt activation and enhancement of apoptotic protein expression.

Journal: The Journal of pharmacology and experimental therapeutics 20060501

Title: Investigation of the cytotoxicity of eukaryotic and prokaryotic antimicrobial peptides in intestinal epithelial cells in vitro.

Journal: Biochemical pharmacology 20060428

Title: Investigation of toroidal pore and oligomerization by melittin using transmission electron microscopy.

Journal: Biochemical and biophysical research communications 20060428

Title: Discovery and characterization of a linear cyclotide from Viola odorata: implications for the processing of circular proteins.

Journal: Journal of molecular biology 20060414

Title: Protein structure prediction using mutually orthogonal Latin squares and a genetic algorithm.

Journal: Biochemical and biophysical research communications 20060407

Title: A novel role of phospholipase A2 in mediating spinal cord secondary injury.

Journal: Annals of neurology 20060401

Title: Structural and thermodynamic aspects of the interaction between heparan sulfate and analogues of melittin.

Journal: Biochemistry 20060307

Title: Secondary heat hyperalgesia induced by melittin in humans.

Journal: European journal of pain (London, England) 20060201

Title: A molecular dynamics study of the bee venom melittin in aqueous solution, in methanol, and inserted in a phospholipid bilayer.

Journal: European biophysics journal : EBJ 20060201

Title: Site-specific amide hydrogen exchange in melittin probed by electron capture dissociation Fourier transform ion cyclotron resonance mass spectrometry.

Journal: The Analyst 20060201

Title: Cycloviolacin H4, a hydrophobic cyclotide from Viola hederaceae.

Journal: Journal of natural products 20060101

Title: Effects of bee venom peptidergic components on rat pain-related behaviors and inflammation.

Journal: Neuroscience 20060101

Title: Target peptide recognition by S100P protein and role of central linker region and dimer interface.

Journal: Protein and peptide letters 20060101

Title: Gene transfer with poly-melittin peptides.

Journal: Bioconjugate chemistry 20060101

Title: Improvement of bacterial cell selectivity of melittin by a single Trp mutation with a peptoid residue.

Journal: Protein and peptide letters 20060101

Title: Multiple PLA2 isoforms regulate taurine release in NIH3T3 mouse fibroblasts.

Journal: Advances in experimental medicine and biology 20060101

Title: [In-vitro activity of two hybrid synthetic peptides having antimicrobial activity against mycobacteria].

Journal: Revista Argentina de microbiologia 20060101

Title: Effect of induced expression of an antimicrobial peptide melittin on Chlamydia trachomatis and Mycoplasma hominis infections in vivo.

Journal: Biochemical and biophysical research communications 20051216

Title: Many-body effect of antimicrobial peptides: on the correlation between lipid's spontaneous curvature and pore formation.

Journal: Biophysical journal 20051201

Title: A surface plasmon resonance sensor for substance P using gold-modified calmodulin and melittin.

Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20051201

Title: Targeting breast and prostate cancers through their hormone receptors.

Journal: Biology of reproduction 20051101

Title: Morphological behavior of lipid bilayers induced by melittin near the phase transition temperature.

Journal: Biophysical journal 20051101

Title: Quantification of the effects of melittin on liposome structure.

Journal: Biochemical Society transactions 20051101

Title: Membrane perturbation effects of peptides derived from the N-termini of unprocessed prion proteins.

Journal: Biochimica et biophysica acta 20051015

Title: Preparation and characterization of melittin-loaded poly (DL-lactic acid) or poly (DL-lactic-co-glycolic acid) microspheres made by the double emulsion method.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20051003

Title: C- versus N-terminally linked melittin-polyethylenimine conjugates: the site of linkage strongly influences activity of DNA polyplexes.

Journal: The journal of gene medicine 20051001

Title: Binding and folding of melittin in the presence of ganglioside GM1 micelles.

Journal: Journal of biomolecular structure & dynamics 20051001

Title: Effect of hexafluoroisopropanol alcohol on the structure of melittin: a molecular dynamics simulation study.

Journal: Protein science : a publication of the Protein Society 20051001

Title: Anti-inflammatory effect of germanium-concentrated yeast against paw oedema is related to the inhibition of arachidonic acid release and prostaglandin E production in RBL 2H3 cells.

Journal: Autonomic & autacoid pharmacology 20051001

Title: [Synthesis of peptide fragment of melittin and the function of rheumatoid arthritis cure].

Journal: Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi 20051001

Title: Ultrafast hydration dynamics in melittin folding and aggregation: helix formation and tetramer self-assembly.

Journal: The journal of physical chemistry. B 20050908

Title: Observation of a dewetting transition in the collapse of the melittin tetramer.

Journal: Nature 20050901

Title: Synthesis and preliminary evaluation of poly(amidoamine)-melittin conjugates as endosomolytic polymers and/or potential anticancer therapeutics.

Journal: International journal of pharmaceutics 20050826

Title: Evaluation and optimization of electron capture dissociation efficiency in fourier transform ion cyclotron resonance mass spectrometry.

Journal: Journal of the American Society for Mass Spectrometry 20050701

Title: Pathogen-induced expression of a cecropin A-melittin antimicrobial peptide gene confers antifungal resistance in transgenic tobacco.

Journal: Journal of experimental botany 20050601

Title: Activation of spinal extracellular signaling-regulated kinases by intraplantar melittin injection.

Journal: Neuroscience letters 20050601

Title: Targeted ablation of prostate carcinoma cells through LH receptor using Hecate-CGbeta conjugate: functional characteristic and molecular mechanism of cell death pathway.

Journal: Experimental biology and medicine (Maywood, N.J.) 20050601

Title: A novel targeted therapy of Leydig and granulosa cell tumors through the luteinizing hormone receptor using a hecate-chorionic gonadotropin beta conjugate in transgenic mice.

Journal: Neoplasia (New York, N.Y.) 20050501

Title: Cholesterol inhibits the lytic activity of melittin in erythrocytes.

Journal: Chemistry and physics of lipids 20050401

Title: A generalized Born formalism for heterogeneous dielectric environments: application to the implicit modeling of biological membranes.

Journal: The Journal of chemical physics 20050322

Title: Inhibition sites in F1-ATPase from bovine heart mitochondria.

Journal: The Biochemical journal 20050315

Title: Melittin-induced bilayer leakage depends on lipid material properties: evidence for toroidal pores.

Journal: Biophysical journal 20050301

Title: Deletion of two C-terminal Gln residues of 12-26-residue fragment of melittin improves its antimicrobial activity.

Journal: Peptides 20050301

Title: Understanding the energetics of helical peptide orientation in membranes.

Journal: Proteins 20050301

Title: Implicit solvent simulations of peptide interactions with anionic lipid membranes.

Journal: Proteins 20050215

Title: Identification and optimization of an antimicrobial peptide from the ant venom toxin pilosulin.

Journal: Archives of biochemistry and biophysics 20050215

Title: Hydroxyl radical probe of the calmodulin-melittin complex interface by electrospray ionization mass spectrometry.

Journal: Journal of the American Society for Mass Spectrometry 20050201

Title: Inhibitory effect of recombinant adenovirus carrying melittin gene on hepatocellular carcinoma.

Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20050101

Title: Similarities of cow mammary gland cytosolic 21-kDa protein, the substrate for protein kinase C, to the 20-kDa myosin light chain from smooth muscle.

Journal: The Journal of veterinary medical science 20050101

Title: Phospholipase A2 activation by melittin enhances spontaneous glutamatergic excitatory transmission in rat substantia gelatinosa neurons.

Journal: Neuroscience 20050101

Title: [The component analysis of tryptophan fluorescence spectra of melittin during its oligomerization].

Journal: Biofizika 20050101

Title: Melittin-induced membrane permeability: a nonosmotic mechanism of cell death.

Journal: In vitro cellular & developmental biology. Animal 20050101

Title: Dissection of antibacterial and toxic activity of melittin: a leucine zipper motif plays a crucial role in determining its hemolytic activity but not antibacterial activity.

Journal: The Journal of biological chemistry 20041231

Title: [Anti-hepatocarcinoma effect of recombinant adenovirus carrying melittin gene].

Journal: Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20041201

Title: Influence of the lipid composition on the kinetics of concerted insertion and folding of melittin in bilayers.

Journal: Biochimica et biophysica acta 20041117

Title: Effect of micellar charge on the conformation and dynamics of melittin.

Journal: European biophysics journal : EBJ 20041101

Title: Dynamic structure of vesicle-bound melittin in a variety of lipid chain lengths by solid-state NMR.

Journal: Biophysical journal 20041101

Title: Increased sensitivity of early apoptotic cells to complement-mediated lysis.

Journal: European journal of immunology 20041101

Title: Antiarthritic effect of bee venom: inhibition of inflammation mediator generation by suppression of NF-kappaB through interaction with the p50 subunit.

Journal: Arthritis and rheumatism 20041101

Title: SERCA structural dynamics induced by ATP and calcium.

Journal: Biochemistry 20041012

Title: Influence of lipid chain unsaturation on membrane-bound melittin: a fluorescence approach.

Journal: Biochimica et biophysica acta 20041011

Title: Interaction of melittin with membrane cholesterol: a fluorescence approach.

Journal: Biophysical journal 20041001

Title: Expression of the melittin gene of Apis cerana cerana in Escherichia coli.

Journal: Protein expression and purification 20040901

Title: Antibiotic activity and synergistic effect of antimicrobial peptide against pathogens from a patient with gallstones.

Journal: Biochemical and biophysical research communications 20040827

Title: Melittin selectively activates capsaicin-sensitive primary afferent fibers.

Journal: Neuroreport 20040806

Title: [The induced apoptosis of recombinant adenovirus carrying melittin gene for hepatocellular carcinoma cell].

Journal: Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20040801

Title: The 2004 Biophysical Society-Avanti Award in Lipids address: roles of bilayer structure and elastic properties in peptide localization in membranes.

Journal: Chemistry and physics of lipids 20040701

Title: Evaluation of different combinations of gated trapping, RF-only mode and trap compensation for in-field MALDI Fourier transform mass spectrometry.

Journal: Journal of the American Society for Mass Spectrometry 20040701

Title: In vitro activity and killing effect of the synthetic hybrid cecropin A-melittin peptide CA(1-7)M(2-9)NH(2) on methicillin-resistant nosocomial isolates of Staphylococcus aureus and interactions with clinically used antibiotics.

Journal: Diagnostic microbiology and infectious disease 20040701

Title: Structure and solvation of melittin in hexafluoroacetone/water.

Journal: Biopolymers 20040615

Title: Biodistributions of intact monoclonal antibodies and fragments of BLCA-38, a new prostate cancer directed antibody.

Journal: Cancer immunology, immunotherapy : CII 20040601

Title: Melittin-induced changes in thylakoid membranes: particle electrophoresis and light scattering study.

Journal: Biophysical chemistry 20040601

Title: A receptor-like kinase from Arabidopsis thaliana is a calmodulin-binding protein.

Journal: The Biochemical journal 20040501

Title: Cytotoxic properties of immunoconjugates containing melittin-like peptide 101 against prostate cancer: in vitro and in vivo studies.

Journal: Cancer immunology, immunotherapy : CII 20040501

Title: Comparative analysis of GFP(UV)-beta1,3-N-acetylglucosaminyltransferase 2 production in two insect-cell-based expression systems.

Journal: Protein expression and purification 20040501

Title: Melittin as model system for probing interactions between proteins and cyclodextrins.

Journal: Proteins 20040501

Title: Structure and solvation of melittin in 1,1,1,3,3,3-hexafluoro-2-propanol/water.

Journal: Biophysical journal 20040501

Title: Induced expression of the antimicrobial peptide melittin inhibits experimental infection by Mycoplasma gallisepticum in chickens.

Journal: Microbes and infection 20040501

Title: [Effect of melittin on apoptosis and necrosis of U2 OS cells].

Journal: Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20040501

Title: Mechanism of Ca2+ activation of the NADPH oxidase 5 (NOX5).

Journal: The Journal of biological chemistry 20040430

Title: Mapping the topology and determination of a low-resolution three-dimensional structure of the calmodulin-melittin complex by chemical cross-linking and high-resolution FTICRMS: direct demonstration of multiple binding modes.

Journal: Biochemistry 20040427

Title: Growth repression in diethylstilbestrol/dimethylbenz[a]anthracene-induced rat mammary gland tumor using Hecate-CGbeta conjugate.

Journal: Experimental biology and medicine (Maywood, N.J.) 20040401

Title: Conformation of the cecropin-melittin hybrid, cecropin A(1-8)-melittin (1-18) antibacterial Peptide.

Journal: Protein and peptide letters 20040401

Title: Energetics of pore formation induced by membrane active peptides.

Journal: Biochemistry 20040330

Title: Melittin induces both time-dependent aggregation and inhibition of Na,K-ATPase from duck salt glands however these two processes appear to occur independently.

Journal: Biochimica et biophysica acta 20040309

Title: GTP-binding protein-independent potentiation by mastoparan of IL-1beta-induced nitric oxide release from insulin-secreting HIT-T15 cells.

Journal: Apoptosis : an international journal on programmed cell death 20040301

Title: Gene transfer with modified polyethylenimines.

Journal: The journal of gene medicine 20040201

Title: Antinematodal activity and the mechanism of the antimicrobial peptide, HP (2-20), against Caenorhabditis elegans.

Journal: Biotechnology letters 20040201

Title: PLA2 and secondary metabolites of arachidonic acid control filopodial behavior in neuronal growth cones.

Journal: Cell motility and the cytoskeleton 20040101

Title: Membrane binding, structure, and localization of cecropin-mellitin hybrid peptides: a site-directed spin-labeling study.

Journal: Biophysical journal 20040101

Title: Excitation of ions by high-harmonic frequency components in Paul and Penning traps and ion guides. I. Selective simultaneous dipolar excitation of high charge states with clipped sinusoidal and non-harmonic waveforms in a linear quadrupole ion guide.

Journal: European journal of mass spectrometry (Chichester, England) 20040101

Title: Altered pain-related behaviors and spinal neuronal responses produced by s.c. injection of melittin in rats.

Journal: Neuroscience 20040101

Title: Temperature dependence of the melittin folding equilibrium studied by means of fluorescence excitation spectra.

Journal: Journal of fluorescence 20040101

Title: Conformational analysis of melittin in solution phase: vibrational circular dichroism study.

Journal: Biopolymers 20031201

Title: Individual substitution analogs of Mel(12-26), melittin's C-terminal 15-residue peptide: their antimicrobial and hemolytic actions.

Journal: FEBS letters 20031106

Title: An implicit membrane generalized born theory for the study of structure, stability, and interactions of membrane proteins.

Journal: Biophysical journal 20031101

Title: Bilayer localization of membrane-active peptides studied in biomimetic vesicles by visible and fluorescence spectroscopies.

Journal: European journal of biochemistry 20031101

Title: Protein in sugar films and in glycerol/water as examined by infrared spectroscopy and by the fluorescence and phosphorescence of tryptophan.

Journal: Biophysical journal 20030901

Title: Comparative activities of cecropin A, melittin, and cecropin A-melittin peptide CA(1-7)M(2-9)NH2 against multidrug-resistant nosocomial isolates of Acinetobacter baumannii.

Journal: Peptides 20030901

Title: Irreversible binding and activity control of the 1,2-diacylglycerol 3-glucosyltransferase from Acholeplasma laidlawii at an anionic lipid bilayer surface.

Journal: Biochemistry 20030819

Title: Effective energy function for proteins in lipid membranes.

Journal: Proteins 20030801

Title: Infrared multiphoton dissociation with a hollow fiber waveguide.

Journal: Analytical chemistry 20030801

Title: Regulatory interaction of sodium channel IQ-motif with calmodulin C-terminal lobe.

Journal: Biochemical and biophysical research communications 20030725

Title: A melittin-related peptide from the skin of the Japanese frog, Rana tagoi, with antimicrobial and cytolytic properties.

Journal: Biochemical and biophysical research communications 20030627

Title: Reactive oxygen species are important mediators of taurine release from skeletal muscle cells.

Journal: American journal of physiology. Cell physiology 20030601

Title: Evidence for membrane thinning effect as the mechanism for peptide-induced pore formation.

Journal: Biophysical journal 20030601

Title: [Cloning and comparative analysis of the venom prepromelittin genes from four wasp species].

Journal: Yi chuan xue bao = Acta genetica Sinica 20030601

Title: Quantification of protein-ligand interactions by mass spectrometry, titration, and H/D exchange: PLIMSTEX.

Journal: Journal of the American Chemical Society 20030507

Title: Effects of sphingomyelin on melittin pore formation.

Journal: Biochimica et biophysica acta 20030502

Title: The antibiotic activity of cationic linear amphipathic peptides: lessons from the action of leucine/lysine copolymers on bacteria of the class Mollicutes.

Journal: European journal of biochemistry 20030501

Title: A novel approach of targeted ablation of mammary carcinoma cells through luteinizing hormone receptors using Hecate-CGbeta conjugate.

Journal: Breast cancer research and treatment 20030501

Title: Differential effects of raloxifene, tamoxifen and fulvestrant on a murine mammary carcinoma.

Journal: Breast cancer research and treatment 20030501

Title: Interactions of mouse Paneth cell alpha-defensins and alpha-defensin precursors with membranes. Prosegment inhibition of peptide association with biomimetic membranes.

Journal: The Journal of biological chemistry 20030418

Title: Impact of infection with recombinant adenovirus carrying melittin gene on CD54 expression in HepG2 cells.

Journal: Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20030401

Title: Functional characterization of bacterial signal peptide OmpA in a baculovirus-mediated expression system.

Journal: Cell structure and function 20030401

Title: D-amino acid residues in peptides and proteins.

Journal: Proteins 20030301

Title: Membrane disrupting lytic peptide conjugates destroy hormone dependent and independent breast cancer cells in vitro and in vivo.

Journal: Breast cancer research and treatment 20030301

Title: Reactive oxygen species regulate swelling-induced taurine efflux in NIH3T3 mouse fibroblasts.

Journal: The Journal of membrane biology 20030301

Title: A comparison of hyperalgesia and neurogenic inflammation induced by melittin and capsaicin in humans.

Journal: Neuroscience letters 20030213

Title: Label-free chiral detection of melittin binding to a membrane.

Journal: Journal of the American Chemical Society 20030205

Title: Lipopolysaccharides in bacterial membranes act like cholesterol in eukaryotic plasma membranes in providing protection against melittin-induced bilayer lysis.

Journal: Biochemistry 20030204

Title: Hybrid global optimization algorithms for protein structure prediction: alternating hybrids.

Journal: Biophysical journal 20030201

Title: Nod factors activate both heterotrimeric and monomeric G-proteins in Vigna unguiculata (L.) Walp.

Journal: Planta 20030201

Title: Exploring peptide membrane interaction using surface plasmon resonance: differentiation between pore formation versus membrane disruption by lytic peptides.

Journal: Biochemistry 20030121

Title: A matrix metalloproteinase 2 cleavable melittin/avidin conjugate specifically targets tumor cells in vitro and in vivo.

Journal: International journal of oncology 20030101

Title: Endosomolysis by masking of a membrane-active agent (EMMA) for cytoplasmic release of macromolecules.

Journal: Bioconjugate chemistry 20030101

Title: Bilayer interfacial properties modulate the binding of amphipathic peptides.

Journal: Chemistry and physics of lipids 20030101

Title: Bimodal regulatory effect of melittin and phospholipase A2-activating protein on human type II secretory phospholipase A2.

Journal: Cell biology international 20030101

Title: Adjuvant action of melittin following intranasal immunisation with tetanus and diphtheria toxoids.

Journal: Journal of drug targeting 20030101

Title: Ionization energies of multiply protonated polypeptides obtained by tandem ionization in Fourier transform mass spectrometers.

Journal: Journal of mass spectrometry : JMS 20021101

Title: Antibacterial and antifungal properties of alpha-helical, cationic peptides in the venom of scorpions from southern Africa.

Journal: European journal of biochemistry 20021001

Title: Sequence requirements for the activity of membrane-active peptides.

Journal: The journal of peptide research : official journal of the American Peptide Society 20021001

Title: Solid-state NMR conformational studies of a melittin-inhibitor complex.

Journal: European biophysics journal : EBJ 20020901

Title: Inhibition by melittin of phosphorylation by protein kinase C of annexin I from cow mammary gland.

Journal: The Journal of veterinary medical science 20020901

Title: Cloaking cytolytic peptides for liposome-based detection and potential drug delivery.

Journal: Biochimica et biophysica acta 20020819

Title: Multiple ion isolation applications in FT-ICR MS: exact-mass MSn internal calibration and purification/interrogation of protein-drug complexes.

Journal: Analytical chemistry 20020801

Title: Conformational and thermodynamic properties of peptide binding to the human S100P protein.

Journal: Protein science : a publication of the Protein Society 20020601

Title: Role of melittin-like region within phospholipase A(2)-activating protein in biological function.

Journal: Toxicon : official journal of the International Society on Toxinology 20020501

Title: Structure and activity of D-Pro14 melittin.

Journal: Journal of protein chemistry 20020501

Title: Cation- and peptide-binding properties of human calmodulin-like skin protein.

Journal: Biochemistry 20020430

Title: Effects of a lytic peptide conjugated to beta HCG on ovarian cancer: studies in vitro and in vivo.

Journal: Gynecologic oncology 20020401

Title: Melittin-GM1 interaction: a model for a side-by-side complex.

Journal: Biochemical and biophysical research communications 20020329

Title: The presence of PEG-lipids in liposomes does not reduce melittin binding but decreases melittin-induced leakage.

Journal: Biochimica et biophysica acta 20020201

Title: Induced expression of melittin, an antimicrobial peptide, inhibits infection by Chlamydia trachomatis and Mycoplasma hominis in a HeLa cell line.

Journal: International journal of antimicrobial agents 20020201

Title: Second derivative fluorescence spectroscopy of tryptophan in proteins.

Journal: Journal of biochemical and biophysical methods 20020104

Title: Arachidonic acid release from rat Leydig cells: the involvement of G protein, phospholipase A2 and regulation of cAMP production.

Journal: The Journal of endocrinology 20020101

Title: [Interaction of local anesthetics with model ion channels].

Journal: Biofizika 20020101

Title: Biphasic vasomotor reflex responses of the hand skin following intradermal injection of melittin into the forearm skin.

Journal: European journal of pain (London, England) 20020101

Title: Melittin enables efficient vesicular escape and enhanced nuclear access of nonviral gene delivery vectors.

Journal: The Journal of biological chemistry 20011214

Title: Delayed oxidant-induced cell death involves activation of phospholipase A2.

Journal: FEBS letters 20011214

Title: Structure of melittin bound to phospholipid micelles studied using hydrogen-deuterium exchange and electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry.

Journal: Journal of the American Society for Mass Spectrometry 20011201

Title: Measurement of the affinity of melittin for zwitterionic and anionic membranes using immobilized lipid biosensors.

Journal: The journal of peptide research : official journal of the American Peptide Society 20011201

Title: Solid-state NMR structure determination of melittin in a lipid environment.

Journal: Biophysical journal 20011101

Title: 'Detergent-like' permeabilization of anionic lipid vesicles by melittin.

Journal: Biochimica et biophysica acta 20011001

Title: Interaction of Na,K-ATPase catalytic subunit with cellular proteins and other endogenous regulators.

Journal: Biochemistry. Biokhimiia 20011001

Title: Barrel-stave model or toroidal model? A case study on melittin pores.

Journal: Biophysical journal 20010901

Title: Membrane fusion between liposomes composed of acidic phospholipids and neutral phospholipids induced by melittin: a differential scanning calorimetric study.

Journal: Journal of biochemistry 20010901

Title: Effects of temporins on molecular dynamics and membrane permeabilization in lipid vesicles.

Journal: The journal of peptide research : official journal of the American Peptide Society 20010901

Title: Self-association and membrane-binding behavior of melittins containing trifluoroleucine.

Journal: Journal of the American Chemical Society 20010801

Title: Effects of melittin on isolated papillary muscles of guinea pig.

Journal: Acta pharmacologica Sinica 20010801

Title: Effects of phospholipase A(2) activating peptides upon GTP-binding protein-evoked adrenocorticotrophin secretion.

Journal: European journal of pharmacology 20010727

Title: Cytolytic peptides induce biphasic permeability changes in mammalian cell membranes.

Journal: Journal of immunological methods 20010601

Title: Mechanisms of regulation of agonist efficacy at the 5-HT(1A) receptor by phospholipid-derived signaling components.

Journal: The Journal of pharmacology and experimental therapeutics 20010601

Title: The effect of cyclization of magainin 2 and melittin analogues on structure, function, and model membrane interactions: implication to their mode of action.

Journal: Biochemistry 20010529

Title: Analysis of antimicrobial peptide interactions with hybrid bilayer membrane systems using surface plasmon resonance.

Journal: Biochimica et biophysica acta 20010502

Title: Mechanisms of tryptophan fluorescence shifts in proteins.

Journal: Biophysical journal 20010501

Title: Melittin exerts multiple effects on the release of free fatty acids from L1210 cells: lack of selective activation of phospholipase A2 by melittin.

Journal: Archives of biochemistry and biophysics 20010501

Title: Use of trinitrophenylation for quantification of protease and peptidase activities.

Journal: Biochemistry. Biokhimiia 20010501

Title: Energetics of target peptide binding by calmodulin reveals different modes of binding.

Journal: The Journal of biological chemistry 20010427

Title: Peptide leucine arginine, a potent immunomodulatory peptide isolated and structurally characterized from the skin of the Northern Leopard frog, Rana pipiens.

Journal: The Journal of biological chemistry 20010330

Title: Rapid down regulation of pyroglutamyl peptidase II activity by arachidonic acid in primary cultures of adenohypophyseal cells.

Journal: Life sciences 20010316

Title: [Cloning and expression of a synthetic gene encoding magainin-melittin hybrid peptide in Escherichia coli and studies on its antibacterial activity].

Journal: Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20010301

Title: Inhibitory effect of melittin on Na+,K+-ATPase from guinea pig myocardial mitochondria.

Journal: Acta pharmacologica Sinica 20010301

Title: Prostaglandin levels in stimulated macrophages are controlled by phospholipase A2-activating protein and by activation of phospholipase C and D.

Journal: The Journal of biological chemistry 20010223

Title: Structure, location, and lipid perturbations of melittin at the membrane interface.

Journal: Biophysical journal 20010201

Title: Pressure-dependent changes in the structure of the melittin alpha-helix determined by NMR.

Journal: Journal of biomolecular NMR 20010201

Title: The lipid charge density at the bilayer surface modulates the effects of melittin on membranes.

Journal: Chemistry and physics of lipids 20010201

Title: Paramecium calmodulin mutants defective in ion channel regulation associate with melittin in the absence of calcium but require it for tertiary collapse.

Journal: Biochemistry 20010130

Title: Polycations induce the release of soluble intermembrane mitochondrial proteins.

Journal: Biochimica et biophysica acta 20010119

Title: Membrane molecule reorientation in an electric field recorded by attenuated total reflection Fourier-transform infrared spectroscopy.

Journal: Biophysical journal 20010101

Title: [Cytotoxic activity of melittin expressed by recombinant vectors in Acholeplasma laidlawii and Mycoplasma hominis cells].

Journal: Genetika 20010101

Title: A cylindrical capacitor ionization source: droplet generation and controlled charge reduction for mass spectrometry.

Journal: Rapid communications in mass spectrometry : RCM 20010101

Title: Effect of controlled expression of the melittin gene on infection caused by Mycoplasma hominis in cell culture.

Journal: Doklady. Biochemistry and biophysics 20010101

Title: Stimulation by melittin of Na+-Ca2+ exchange current in ventricular myocytes of guinea pigs.

Journal: Acta pharmacologica Sinica 20010101

Title: [Intensification of the interaction of IgG with C1q in the presence of melittin as a possible reason for anaphylaxis under the effect of bee venom].

Journal: Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20010101

Title: Pyridoxal-phosphate-6-azophenyl-2',4'-disulfonate (PPADS), a putative P2Y(1) receptor antagonist, blocks signaling at a site distal to the receptor in Madin-Darby canine kidney-D(1) cells.

Journal: The Journal of pharmacology and experimental therapeutics 20000101

Title: Antimicrobial peptides melittin and cecropin inhibit replication of human immunodeficiency virus 1 by suppressing viral gene expression.

Journal: The Journal of general virology 19980401

Title: Expression of antimicrobial peptides has an antitumour effect in human cells.

Journal: Biochemical and biophysical research communications 19980126

Title: Synergism between mellitin and phospholipase A2 from bee venom: apparent activation by intervesicle exchange of phospholipids.

Journal: Biochemistry 19970401

Title: Enhancement of stress-induced synthesis of hsp27 and alpha B crystallin by modulators of the arachidonic acid cascade.

Journal: Journal of cellular physiology 19960201

Title: The amino-terminal peptide of HIV-1 glycoprotein 41 lyses human erythrocytes and CD4+ lymphocytes.

Journal: Biochimica et biophysica acta 19920825

Title: Steiner MR, et al. Responses of purified phospholipases A2 to phospholipase A2 activating protein (PLAP) and Melittin. Biochim Biophys Acta. 1993 Feb 10;1166(1):124-30.

Title: Alonezi S, et al. Metabolomic Profiling of the Effects of Melittin on Cisplatin Resistant and Cisplatin Sensitive Ovarian Cancer Cells Using Mass Spectrometry and Biolog Microarray Technology. Metabolites. 2016 Oct 13;6(4). pii: E35.

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SDS
Tags:20449-79-0 Molecular Formula|20449-79-0 MDL|20449-79-0 SMILES|20449-79-0 Melittin (honeybee)
Catalog No.: AA00BDR3
20449-79-0,MFCD00718095
20449-79-0 | Melittin (honeybee)
Pack Size: 1mg
Purity: ≥ 98% (HPLC)
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$245.00 $171.00
Pack Size: 5mg
Purity: ≥ 98% (HPLC)
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$682.00 $477.00
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Technical Information
Catalog Number: AA00BDR3
Chemical Name: Melittin (honeybee)
CAS Number: 20449-79-0
Molecular Formula: C131H229N39O31
Molecular Weight: 2846.4627
MDL Number: MFCD00718095
SMILES: NCCCCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NCC(=O)NC(C(=O)N1CCCC1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N)CCC(=O)N)CCC(=O)N)CCCNC(=N)N)CCCCN)CCCNC(=N)N)CCCCN)C(CC)C)Cc1c[nH]c2c1cccc2)CO)C(CC)C)CC(C)C)C)CC(C)C)C(O)C)C(O)C)CC(C)C)C(C)C)NC(=O)C(NC(=O)C(C(C)C)NC(=O)C(NC(=O)CNC(=O)C(C(CC)C)NC(=O)CN)C)CC(C)C
Properties
Complexity: 6300  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 28  
Heavy Atom Count: 201  
Hydrogen Bond Acceptor Count: 37  
Hydrogen Bond Donor Count: 41  
Rotatable Bond Count: 99  
XLogP3: -2.7  
Literature fold

Title: Melittin induces PTCH1 expression by down-regulating MeCP2 in human hepatocellular carcinoma SMMC-7721 cells.

Journal: Toxicology and applied pharmacology20151001

Title: Activation of tetrodotoxin-resistant sodium channel NaV1.9 in rat primary sensory neurons contributes to melittin-induced pain behavior.

Journal: Neuromolecular medicine20130301

Title: Cytolytic nanoparticles attenuate HIV-1 infectivity.

Journal: Antiviral therapy20130101

Title: Binding and reorientation of melittin in a POPC bilayer: computer simulations.

Journal: Biochimica et biophysica acta20121201

Title: Melittin suppresses VEGF-A-induced tumor growth by blocking VEGFR-2 and the COX-2-mediated MAPK signaling pathway.

Journal: Journal of natural products20121126

Title: Melittin has an inhibitory effect on TNF-α-induced migration of human aortic smooth muscle cells by blocking the MMP-9 expression.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association20121101

Title: Honey bee (Apis mellifera) venom induces AIM2 inflammasome activation in human keratinocytes.

Journal: Allergy20121101

Title: Involvement of peripheral NMDA receptor in melittin-induced thermographic flare.

Journal: Neurochemical research20121001

Title: Spectroscopic and computational study of melittin, cecropin A, and the hybrid peptide CM15.

Journal: The journal of physical chemistry. B20120906

Title: Melittin initiates dopamine transporter internalization and recycling in transfected HEK-293 cells.

Journal: European journal of pharmacology20120905

Title: Evaluation of molecularity of rate-limiting step of pore formation by antimicrobial peptides studied using mitochondria as a biosensor.

Journal: Toxicology in vitro : an international journal published in association with BIBRA20120901

Title: Protein flexibility is key to cisplatin crosslinking in calmodulin.

Journal: Protein science : a publication of the Protein Society20120901

Title: Aminoarabinose is essential for lipopolysaccharide export and intrinsic antimicrobial peptide resistance in Burkholderia cenocepacia(†).

Journal: Molecular microbiology20120901

Title: Molecular response and cooperative behavior during the interactions of melittin with a membrane: dissipative quartz crystal microbalance experiments and simulations.

Journal: The journal of physical chemistry. B20120809

Title: Gain-of-function analogues of the pore-forming peptide melittin selected by orthogonal high-throughput screening.

Journal: Journal of the American Chemical Society20120801

Title: Anticancer peptide NK-2 targets cell surface sulphated glycans rather than sialic acids.

Journal: Biological chemistry20120801

Title: The innate reactivity of a membrane associated peptide towards lipids: acyl transfer to melittin without enzyme catalysis.

Journal: Organic & biomolecular chemistry20120728

Title: Melittin modulates keratinocyte function through P2 receptor-dependent ADAM activation.

Journal: The Journal of biological chemistry20120706

Title: NMR studies on the monomer-tetramer transition of melittin in an aqueous solution at high and low temperatures.

Journal: European biophysics journal : EBJ20120701

Title: Reaction of singlet oxygen with tryptophan in proteins: a pronounced effect of the local environment on the reaction rate.

Journal: Journal of the American Chemical Society20120613

Title: Effects of sweet bee venom pharmacopuncture treatment for chemotherapy-induced peripheral neuropathy: a case series.

Journal: Integrative cancer therapies20120601

Title: Novel short AMP: design and activity study.

Journal: Protein and peptide letters20120601

Title: In vitro activities of antimicrobial cationic peptides; melittin and nisin, alone or in combination with antibiotics against Gram-positive bacteria.

Journal: Journal of chemotherapy (Florence, Italy)20120601

Title: In situ imaging of honeybee (Apis mellifera) venom components from aqueous and aluminum hydroxide-adsorbed venom immunotherapy preparations.

Journal: The Journal of allergy and clinical immunology20120501

Title: Charge distribution and imperfect amphipathicity affect pore formation by antimicrobial peptides.

Journal: Biochimica et biophysica acta20120501

Title: The dynamics of melittin-induced membrane permeability.

Journal: European biophysics journal : EBJ20120501

Title: In vitro activity of several antimicrobial peptides against colistin-susceptible and colistin-resistant Acinetobacter baumannii.

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases20120401

Title: Truncated peptides from melittin and its analog with high lytic activity at endosomal pH enhance branched polyethylenimine-mediated gene transfection.

Journal: The journal of gene medicine20120401

Title: Effects of a non-selective TRPC channel blocker, SKF-96365, on melittin-induced spontaneous persistent nociception and inflammatory pain hypersensitivity.

Journal: Neuroscience bulletin20120401

Title: Difference between magainin-2 and melittin assemblies in phosphatidylcholine bilayers: results from coarse-grained simulations.

Journal: The journal of physical chemistry. B20120308

Title: Production of human antibody fragments binding to melittin and phospholipase A2 in Africanised bee venom: minimising venom toxicity.

Journal: Basic & clinical pharmacology & toxicology20120301

Title: Trivalent ultrashort lipopeptides are potent pH dependent antifungal agents.

Journal: Journal of medicinal chemistry20120209

Title: Combined electron transfer dissociation-collision-induced dissociation fragmentation in the mass spectrometric distinction of leucine, isoleucine, and hydroxyproline residues in Peptide natural products.

Journal: Journal of proteome research20120203

Title: Consequences of alteration in leucine zipper sequence of melittin in its neutralization of lipopolysaccharide-induced proinflammatory response in macrophage cells and interaction with lipopolysaccharide.

Journal: The Journal of biological chemistry20120113

Title: Investigation of model membrane disruption mechanism by melittin using pulse electron paramagnetic resonance spectroscopy and cryogenic transmission electron microscopy.

Journal: The journal of physical chemistry. B20120112

Title: Characterization of in vitro hemostatic peptide effects by thromboelastography.

Journal: Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis20120101

Title: Protective effect of melittin on inflammation and apoptosis in acute liver failure.

Journal: Apoptosis : an international journal on programmed cell death20120101

Title: Anti-cancer effect of bee venom toxin and melittin in ovarian cancer cells through induction of death receptors and inhibition of JAK2/STAT3 pathway.

Journal: Toxicology and applied pharmacology20120101

Title: Episodic hemorrhage during honeybee venom anaphylaxis: potential mechanisms.

Journal: Journal of investigational allergology & clinical immunology20120101

Title: The mediation of the central histaminergic system in the pressor effect of intracerebroventricularly injected melittin, a phospholipase A2 activator, in normotensive rats.

Journal: Prostaglandins, leukotrienes, and essential fatty acids20120101

Title: Respiratory syncytial virus reverses airway hyperresponsiveness to methacholine in ovalbumin-sensitized mice.

Journal: PloS one20120101

Title: Interaction of melittin peptides with perfluorocarbon nanoemulsion particles.

Journal: The journal of physical chemistry. B20111229

Title: PEG-stabilized lipid disks as carriers for amphiphilic antimicrobial peptides.

Journal: Journal of controlled release : official journal of the Controlled Release Society20111220

Title: Melittin inhibits cerulein-induced acute pancreatitis via inhibition of the JNK pathway.

Journal: International immunopharmacology20111201

Title: NMR studies on thermal stability of α-helix conformation of melittin in pure ethanol and ethanol-water mixture solvents.

Journal: Journal of peptide science : an official publication of the European Peptide Society20111201

Title: Melittin adsorption and lipid monolayer disruption at liquid-liquid interfaces.

Journal: Langmuir : the ACS journal of surfaces and colloids20111115

Title: Clinical efficacy of a specifically targeted antimicrobial peptide mouth rinse: targeted elimination of Streptococcus mutans and prevention of demineralization.

Journal: Caries research20111101

Title: Melittin attenuates liver injury in thioacetamide-treated mice through modulating inflammation and fibrogenesis.

Journal: Experimental biology and medicine (Maywood, N.J.)20111101

Title: The structure, molecular dynamics, and energetics of centrin-melittin complex.

Journal: Proteins20111101

Title: Protective effects of melittin on transforming growth factor-β1 injury to hepatocytes via anti-apoptotic mechanism.

Journal: Toxicology and applied pharmacology20111015

Title: Analysis of the role of Mg²⁺ on conformational change and target recognition by ciliate Euplotes octocarinatus centrin.

Journal: Journal of photochemistry and photobiology. B, Biology20111005

Title: Melittin enhances apoptosis through suppression of IL-6/sIL-6R complex-induced NF-κB and STAT3 activation and Bcl-2 expression for human fibroblast-like synoviocytes in rheumatoid arthritis.

Journal: Joint, bone, spine : revue du rhumatisme20111001

Title: Evidence for α-helices in the gas phase: a case study using Melittin from honey bee venom.

Journal: The Analyst20110907

Title: An impedance QCM study on the partitioning of bioactive compounds in supported phospholipid bilayers.

Journal: Colloids and surfaces. B, Biointerfaces20110901

Title: Influence of the arrangement and secondary structure of melittin peptides on the formation and stability of toroidal pores.

Journal: Biochimica et biophysica acta20110901

Title: Myosins and DYNLL1/LC8 in the honey bee (Apis mellifera L.) brain.

Journal: Journal of insect physiology20110901

Title: Penetration of antibody-opsonized cells by the membrane attack complex of complement promotes Ca(2+) influx and induces streamers.

Journal: European journal of immunology20110801

Title: High content analysis to determine cytotoxicity of the antimicrobial peptide, melittin and selected structural analogs.

Journal: Peptides20110801

Title: Membrane cholesterol modulates the cytolytic mechanism of myotoxin II, a Lys49 phospholipase A2 homologue from the venom of Bothrops asper.

Journal: Cell biochemistry and function20110701

Title: Acetylcholine and norepinephrine mediate GABAergic but not glycinergic transmission enhancement by melittin in adult rat substantia gelatinosa neurons.

Journal: Journal of neurophysiology20110701

Title: Tat peptide-calmodulin binding studies and bioinformatics of HIV-1 protein-calmodulin interactions.

Journal: Proteins20110701

Title: Glucose interactions with a model peptide.

Journal: Proteins20110701

Title: W-Band pulse EPR distance measurements in peptides using Gd(3+)-dipicolinic acid derivatives as spin labels.

Journal: Physical chemistry chemical physics : PCCP20110614

Title: Anti-cancer effect of bee venom in prostate cancer cells through activation of caspase pathway via inactivation of NF-κB.

Journal: The Prostate20110601

Title: Effects of SKF-96365, a TRPC inhibitor, on melittin-induced inward current and intracellular Ca2+ rise in primary sensory cells.

Journal: Neuroscience bulletin20110601

Title: Online monitoring of metabolism and morphology of peptide-treated neuroblastoma cancer cells and keratinocytes.

Journal: Journal of bioenergetics and biomembranes20110601

Title: Gangliosides inhibit bee venom melittin cytotoxicity but not phospholipase A(2)-induced degranulation in mast cells.

Journal: Toxicology and applied pharmacology20110501

Title: Melittin liposomes surface modified with poloxamer 188: in vitro characterization and in vivo evaluation.

Journal: Die Pharmazie20110501

Title: Melittin activates TRPV1 receptors in primary nociceptive sensory neurons via the phospholipase A2 cascade pathways.

Journal: Biochemical and biophysical research communications20110429

Title: Electron detachment dissociation for top-down mass spectrometry of acidic proteins.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany)20110411

Title: Expression and functional characterization of a recombinant targeted toxin with an uPA cleavable linker in Pichia pastoris.

Journal: Protein expression and purification20110401

Title: Quantification of protein-protein interactions with chemical cross-linking and mass spectrometry.

Journal: Journal of proteome research20110401

Title: Effects induced by Apis mellifera venom and its components in experimental models of nociceptive and inflammatory pain.

Journal: Toxicon : official journal of the International Society on Toxinology20110401

Title: Oligopeptidase B from Serratia proteamaculans. II. Enzymatic characteristics: substrate analysis, influence of calcium ions, pH and temperature dependences.

Journal: Biochemistry. Biokhimiia20110401

Title: Structural dynamics of a lytic peptide interacting with a supported lipid bilayer.

Journal: Biophysical journal20110302

Title: Helix conformation of a small peptide melittin in a methanol-water mixed solvent studied by NMR.

Journal: Protein and peptide letters20110301

Title: Acyl transfer from phosphocholine lipids to melittin.

Journal: Chemical communications (Cambridge, England)20110207

Title: Ultrastructural observation on sterilization of melittin.

Journal: Science China. Life sciences20110201

Title: Characterization of honeybee venom by MALDI-TOF and nanoESI-QqTOF mass spectrometry.

Journal: Journal of pharmaceutical and biomedical analysis20110125

Title: Melittin stimulates fatty acid release through non-phospholipase-mediated mechanisms and interacts with the dopamine transporter and other membrane-spanning proteins.

Journal: European journal of pharmacology20110115

Title: Monitoring membrane binding and insertion of peptides by two-color fluorescent label.

Journal: Biochimica et biophysica acta20110101

Title: Tryptophan orientations in membrane-bound gramicidin and melittin-a comparative linear dichroism study on transmembrane and surface-bound peptides.

Journal: Biochimica et biophysica acta20110101

Title: Multifunctional CPP polymer system for tumor-targeted pDNA and siRNA delivery.

Journal: Methods in molecular biology (Clifton, N.J.)20110101

Title: Membrane partitioning: 'classical' and 'nonclassical' hydrophobic effects.

Journal: The Journal of membrane biology20110101

Title: The role of electrostatic interactions in the membrane binding of melittin.

Journal: Journal of molecular recognition : JMR20110101

Title: Melittin restores proteasome function in an animal model of ALS.

Journal: Journal of neuroinflammation20110101

Title: Melittin inhibits atherosclerosis in LPS/high-fat treated mice through atheroprotective actions.

Journal: Journal of atherosclerosis and thrombosis20110101

Title: Construction and characterization of an anti-asialoglycoprotein receptor single-chain variable-fragment-targeted melittin.

Journal: Biotechnology and applied biochemistry20110101

Title: Magnetic 'fishing' assay to screen small-molecule mixtures for modulators of protein-protein interactions.

Journal: Analytical chemistry20101201

Title: Melittin promotes exocytosis in neuroendocrine cells through the activation of phospholipase A₂.

Journal: Regulatory peptides20101130

Title: Acute physiopathological effects of honeybee (Apis mellifera) envenoming by subcutaneous route in a mouse model.

Journal: Toxicon : official journal of the International Society on Toxinology20101101

Title: The synergistic action of melittin and phospholipase A2 with lipid membranes: development of linear dichroism for membrane-insertion kinetics.

Journal: Protein and peptide letters20101101

Title: A gigaseal obtained with a self-assembled long-lifetime lipid bilayer on a single polyelectrolyte multilayer-filled nanopore.

Journal: ACS nano20100928

Title: Quantification of melittin and apamin in bee venom lyophilized powder from Apis mellifera by liquid chromatography-diode array detector-tandem mass spectrometry.

Journal: Analytical biochemistry20100915

Title: Cell-selective lysis by novel analogues of melittin against human red blood cells and Escherichia coli.

Journal: Biochemistry20100914

Title: Antibiotic and synergistic effect of Leu-Lys rich peptide against antibiotic resistant microorganisms isolated from patients with cholelithiasis.

Journal: Biochemical and biophysical research communications20100903

Title: Africanized honey bee (Apis mellifera) venom profiling: Seasonal variation of melittin and phospholipase A(2) levels.

Journal: Toxicon : official journal of the International Society on Toxinology20100901

Title: Characterization of perfluorooctylbromide-based nanoemulsion particles using atomistic molecular dynamics simulations.

Journal: The journal of physical chemistry. B20100812

Title: Antimicrobial peptides bind more strongly to membrane pores.

Journal: Biochimica et biophysica acta20100801

Title: Trypanosoma cruzi: synergistic cytotoxicity of multiple amphipathic anti-microbial peptides to T. cruzi and potential bacterial hosts.

Journal: Experimental parasitology20100801

Title: Antimicrobial peptides in toroidal and cylindrical pores.

Journal: Biochimica et biophysica acta20100801

Title: Identification of a novel melittin isoform from Africanized Apis mellifera venom.

Journal: Peptides20100801

Title: Topology and dynamics of melittin within the liposome revealed by a combination of mass spectrometry and chemical modification.

Journal: Biochemical and biophysical research communications20100618

Title: An OEGylated thiol monolayer for the tethering of liposomes and the study of liposome interactions.

Journal: Talanta20100615

Title: A unique protein labeling system based on melittin and the non-covalent binding-induced pyrene excimer.

Journal: Chemical communications (Cambridge, England)20100607

Title: A metal-supported biomimetic micromembrane allowing the recording of single-channel activity and of impedance spectra of membrane proteins.

Journal: Bioelectrochemistry (Amsterdam, Netherlands)20100601

Title: Effect of α-helical peptides on liposome structure: a comparative study of melittin and alamethicin.

Journal: Journal of colloid and interface science20100601

Title: Recognition, neutralization, and clearance of target peptides in the bloodstream of living mice by molecularly imprinted polymer nanoparticles: a plastic antibody.

Journal: Journal of the American Chemical Society20100519

Title: Selective death of human breast cancer cells by lytic immunoliposomes: Correlation with their HER2 expression level.

Journal: Cancer letters20100428

Title: Calcium-induced structural transitions of the calmodulin-melittin system studied by electrospray mass spectrometry: conformational subpopulations and metal-unsaturated intermediates.

Journal: Biochemistry20100427

Title: Inhibition of Escherichia coli ATP synthase by amphibian antimicrobial peptides.

Journal: International journal of biological macromolecules20100401

Title: Melittin induces apoptotic features in Candida albicans.

Journal: Biochemical and biophysical research communications20100326

Title: Impact of amino acid replacements on in vitro permeation enhancement and cytotoxicity of the intestinal absorption promoter, melittin.

Journal: International journal of pharmaceutics20100315

Title: IL-4 induces protection of vascular endothelial cells against killing by complement and melittin through lipid biosynthesis.

Journal: European journal of immunology20100301

Title: Design, synthesis and antimicrobial properties of non-hemolytic cationic alpha-cyclopeptoids.

Journal: Bioorganic & medicinal chemistry20100301

Title: Melittin suppresses PMA-induced tumor cell invasion by inhibiting NF-kappaB and AP-1-dependent MMP-9 expression.

Journal: Molecules and cells20100227

Title: Bee venom suppresses PMA-mediated MMP-9 gene activation via JNK/p38 and NF-kappaB-dependent mechanisms.

Journal: Journal of ethnopharmacology20100217

Title: Micelle-bound structures and dynamics of the hinge deleted analog of melittin and its diastereomer: implications in cell selective lysis by D-amino acid containing antimicrobial peptides.

Journal: Biochimica et biophysica acta20100201

Title: Real-time monitoring of melittin-induced pore and tubule formation from supported lipid bilayers and its physiological relevance.

Journal: Chemistry and physics of lipids20100201

Title: Dissociation of calmodulin-target peptide complexes by the lipid mediator sphingosylphosphorylcholine: implications in calcium signaling.

Journal: The Journal of biological chemistry20100115

Title: The effect of calcium ions and peptide ligands on the relative stabilities of the calmodulin dumbbell and compact structures.

Journal: The journal of physical chemistry. B20100114

Title: Vesicle budding induced by a pore-forming peptide.

Journal: Journal of the American Chemical Society20100113

Title: Synthesis and in vitro testing of new potent polyacridine-melittin gene delivery peptides.

Journal: Bioconjugate chemistry20100101

Title: [Comparative studies of structural properties of melittin in water and trifluroethanol/water mixture by the molecular dynamics method].

Journal: Biofizika20100101

Title: Surface plasmon resonance spectroscopy for studying the membrane binding of antimicrobial peptides.

Journal: Methods in molecular biology (Clifton, N.J.)20100101

Title: The anti-arthritic effects of synthetic melittin on the complete Freund's adjuvant-induced rheumatoid arthritis model in rats.

Journal: The American journal of Chinese medicine20100101

Title: Secretory expression of porcine interferon-gamma in baculovirus using HBM signal peptide and its inhibition activity on the replication of porcine reproductive and respiratory syndrome virus.

Journal: Veterinary immunology and immunopathology20091215

Title: Melittin-regenerated purple membrane.

Journal: Biochemistry. Biokhimiia20091201

Title: Evaluation of intestinal absorption and mucosal toxicity using two promoters. II. Rat instillation and perfusion studies.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences20091105

Title: Evaluation of intestinal absorption enhancement and local mucosal toxicity of two promoters. I. Studies in isolated rat and human colonic mucosae.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences20091105

Title: Hydrogen bonding and solvent polarity markers in the uv resonance raman spectrum of tryptophan: application to membrane proteins.

Journal: The journal of physical chemistry. B20091105

Title: Interactions of 2,2,2-trifluoroethanol with melittin.

Journal: Magnetic resonance in chemistry : MRC20091101

Title: Assessment of the multiphase interaction between a membrane disrupting peptide and a lipid membrane.

Journal: The journal of physical chemistry. B20091029

Title: Cause and effect of melittin-induced pore formation: a computational approach.

Journal: Langmuir : the ACS journal of surfaces and colloids20091020

Title: Formation of individual protein channels in lipid bilayers suspended in nanopores.

Journal: Colloids and surfaces. B, Biointerfaces20091015

Title: Phospholipid flip-flop modulated by transmembrane peptides WALP and melittin.

Journal: Journal of structural biology20091001

Title: In vitro- and in vivo-targeted tumor lysis by an MMP2 cleavable melittin-LAP fusion protein.

Journal: International journal of oncology20091001

Title: Molecularly targeted nanocarriers deliver the cytolytic peptide melittin specifically to tumor cells in mice, reducing tumor growth.

Journal: The Journal of clinical investigation20090901

Title: Postantibiotic effect of purified melittin from honeybee (Apis mellifera) venom against Escherichia coli and Staphylococcus aureus.

Journal: Journal of Asian natural products research20090901

Title: Activation of ERK1/2 in the primary injury site is required to maintain melittin-enhanced wind-up of rat spinal wide-dynamic-range neurons.

Journal: Neuroscience letters20090814

Title: Design of high payload PLGA nanoparticles containing melittin/sodium dodecyl sulfate complex by the hydrophobic ion-pairing technique.

Journal: Drug development and industrial pharmacy20090801

Title: The RH 421 styryl dye induced, pore model-dependent modulation of antimicrobial peptides activity in reconstituted planar membranes.

Journal: Biochimica et biophysica acta20090801

Title: Ventral cochlear nucleus responses to contralateral sound are mediated by commissural and olivocochlear pathways.

Journal: Journal of neurophysiology20090801

Title: Simultaneous collision induced dissociation of the charge reduced parent ion during electron capture dissociation.

Journal: Analytical chemistry20090801

Title: [Cloning and expression of a gene encoding shortened LfcinB(1-15)-Melittin(5-12) hybrid peptide in Escherichia coli BL21(DE3)].

Journal: Sheng wu gong cheng xue bao = Chinese journal of biotechnology20090701

Title: Hecate-CGbeta conjugate and gonadotropin suppression shows two distinct mechanisms of action in the treatment of adrenocortical tumors in transgenic mice expressing Simian Virus 40 T antigen under inhibin-alpha promoter.

Journal: Endocrine-related cancer20090601

Title: Evidence for a Ca(2+)-specific conformational change in avian thymic hormone, a high-affinity beta-parvalbumin.

Journal: Biochemistry20090512

Title: Surfactant protein-D regulates the postnatal maturation of pulmonary surfactant lipid pool sizes.

Journal: Journal of applied physiology (Bethesda, Md. : 1985)20090501

Title: Targeting the cancer stroma with a fibroblast activation protein-activated promelittin protoxin.

Journal: Molecular cancer therapeutics20090501

Title: Free energies of molecular bound states in lipid bilayers: lethal concentrations of antimicrobial peptides.

Journal: Biophysical journal20090422

Title: Thermodynamics of melittin binding to lipid bilayers. Aggregation and pore formation.

Journal: Biochemistry20090331

Title: Specificity of ion-protein interactions: complementary and competitive effects of tetrapropylammonium, guanidinium, sulfate, and chloride ions.

Journal: The journal of physical chemistry. B20090312

Title: Melittin, a major component of bee venom, sensitizes human hepatocellular carcinoma cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis by activating CaMKII-TAK1-JNK/p38 and inhibiting IkappaBalpha kinase-NFkappaB.

Journal: The Journal of biological chemistry20090206

Title: Synthesis and biological evaluation of a bioresponsive and endosomolytic siRNA-polymer conjugate.

Journal: Molecular pharmaceutics20090101

Title: Cardiovascular effect of peripheral injected melittin in normotensive conscious rats: Mediation of the central cholinergic system.

Journal: Prostaglandins, leukotrienes, and essential fatty acids20090101

Title: Engineering stabilized vascular endothelial growth factor-A antagonists: synthesis, structural characterization, and bioactivity of grafted analogues of cyclotides.

Journal: Journal of medicinal chemistry20081225

Title: On the mechanism of pore formation by melittin.

Journal: The Journal of biological chemistry20081205

Title: A novel cationic-peptide coating for the prevention of microbial colonization on contact lenses.

Journal: Journal of applied microbiology20081201

Title: Label-free measurements of molecular transport across liposome membranes using evanescent-wave sensing.

Journal: Chemphyschem : a European journal of chemical physics and physical chemistry20081201

Title: Extracellular signal-regulated kinases mediate melittin-induced hypersensitivity of spinal neurons to chemical and thermal but not mechanical stimuli.

Journal: Brain research bulletin20081125

Title: Monitoring orientation and dynamics of membrane-bound melittin utilizing dansyl fluorescence.

Journal: The journal of physical chemistry. B20081106

Title: Melittin-lipid bilayer interactions and the role of cholesterol.

Journal: Biophysical journal20081101

Title: The lipid composition determines the kinetics of adhesion and spreading of liposomes on mercury electrodes.

Journal: Bioelectrochemistry (Amsterdam, Netherlands)20081101

Title: Roles of peripheral P2X and P2Y receptors in the development of melittin-induced nociception and hypersensitivity.

Journal: Neurochemical research20081001

Title: Probing the steric barrier of nonionic surfactant vesicles with melittin.

Journal: Biochimica et biophysica acta20081001

Title: Melittin-lipid interaction: a comparative study using liposomes, micelles and bilayer disks.

Journal: Biochimica et biophysica acta20081001

Title: Influence of antimicrobial peptides on the formation of nonlamellar lipid mesophases.

Journal: Biochimica et biophysica acta20081001

Title: Toroidal pores formed by antimicrobial peptides show significant disorder.

Journal: Biochimica et biophysica acta20081001

Title: Dual-color fluorescence-burst analysis to study pore formation and protein-protein interactions.

Journal: Methods (San Diego, Calif.)20081001

Title: Characterization of melittin binding to Euplotes octocarinatus centrin.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy20080901

Title: Honeybee venom induces calcium-dependent but caspase-independent apoptotic cell death in human melanoma A2058 cells.

Journal: Toxicon : official journal of the International Society on Toxinology20080801

Title: Interdomain cooperativity of calmodulin bound to melittin preferentially increases calcium affinity of sites I and II.

Journal: Proteins20080601

Title: Melittin prevents liver cancer cell metastasis through inhibition of the Rac1-dependent pathway.

Journal: Hepatology (Baltimore, Md.)20080601

Title: Targeted therapy for adrenocortical tumors in transgenic mice through their LH receptor by Hecate-human chorionic gonadotropin beta conjugate.

Journal: Endocrine-related cancer20080601

Title: Pleurocidin-derived antifungal peptides with selective membrane-disruption effect.

Journal: Biochemical and biophysical research communications20080509

Title: Crystallization and preliminary X-ray characterization of full-length Chlamydomonas reinhardtii centrin.

Journal: Acta crystallographica. Section F, Structural biology and crystallization communications20080501

Title: Melittin-induced [Ca2+]i increases and subsequent death in canine renal tubular cells.

Journal: Human & experimental toxicology20080501

Title: Roles of peripheral mitogen-activated protein kinases in melittin-induced nociception and hyperalgesia.

Journal: Neuroscience20080409

Title: Cationic peptide-induced remodelling of model membranes: direct visualization by in situ atomic force microscopy.

Journal: Journal of structural biology20080401

Title: Inhibition of the ATPase activity of the catalytic portion of ATP synthases by cationic amphiphiles.

Journal: Biochimica et biophysica acta20080401

Title: Synthesis and characterization of stable fluorocarbon nanostructures as drug delivery vehicles for cytolytic peptides.

Journal: Nano letters20080401

Title: Label-free detection of melittin binding to a membrane using electrochemical-localized surface plasmon resonance.

Journal: Analytical chemistry20080315

Title: Probing melittin helix-coil equilibria in solutions and vesicles.

Journal: The journal of physical chemistry. B20080313

Title: Melittin interaction with sulfated cell surface sugars.

Journal: Biochemistry20080304

Title: Melittin exhibits necrotic cytotoxicity in gastrointestinal cells which is attenuated by cholesterol.

Journal: Biochemical pharmacology20080301

Title: Phospholipase A2 activation enhances inhibitory synaptic transmission in rat substantia gelatinosa neurons.

Journal: Journal of neurophysiology20080301

Title: Surface-induced dissociation of peptides and protein complexes in a quadrupole/time-of-flight mass spectrometer.

Journal: Analytical chemistry20080301

Title: Membrane-proximal cytoplasmic domain of Moloney murine leukemia virus envelope tail facilitates fusion.

Journal: Experimental and molecular pathology20080201

Title: Melittin induces Bcl-2 and caspase-3-dependent apoptosis through downregulation of Akt phosphorylation in human leukemic U937 cells.

Journal: Toxicon : official journal of the International Society on Toxinology20080101

Title: Amphipathic alpha-helical peptide, HP (2-20), and its analogues derived from Helicobacter pylori: pore formation mechanism in various lipid compositions.

Journal: Biochimica et biophysica acta20080101

Title: Effects of melittin on the production of matrix metalloproteinase-1 and -3 in rheumatoid arthritic fibroblast-like synoviocytes.

Journal: Journal of pharmacological sciences20080101

Title: [Isolation and properties of cysteine protease from Serratia proteamaculans 94].

Journal: Bioorganicheskaia khimiia20080101

Title: Comprehensive characterization of molecular interactions based on nanomechanics.

Journal: PloS one20080101

Title: Structural and thermodynamic analyses of the interaction between melittin and lipopolysaccharide.

Journal: Biochimica et biophysica acta20071201

Title: Cardiovascular effects of centrally injected melittin in hemorrhaged hypotensive rats: the investigation of peripheral mechanisms.

Journal: Neuropeptides20071201

Title: [Effects of melittin on growth and angiogenesis of human hepatocellular carcinoma BEL-7402 cell xenografts in nude mice].

Journal: Ai zheng = Aizheng = Chinese journal of cancer20071201

Title: [Enhancing transfection efficiency of polyethylenimine by a hydrophobic peptide from bee venom].

Journal: Zhongguo shi yan xue ye xue za zhi20071201

Title: Cell selectivity of an antimicrobial peptide melittin diastereomer with D-amino acid in the leucine zipper sequence.

Journal: Journal of biochemistry and molecular biology20071130

Title: Design and synthesis of novel antibacterial peptide-resin conjugates.

Journal: Bioorganic & medicinal chemistry letters20071101

Title: Spectrally and time-resolved fluorescence spectroscopic study on melittin-calmodulin interaction.

Journal: Journal of biochemistry20071101

Title: [Melittin inhibits proliferation and induces apoptosis of malignant human glioma cells].

Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University20071101

Title: [Preparation and in vitro tumor cells selectivity of sterically stabilized immunoliposomal peptides in bee venom].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica20071101

Title: Application of principal component analysis in protein unfolding: an all-atom molecular dynamics simulation study.

Journal: The Journal of chemical physics20071028

Title: Melittin: a membrane-active peptide with diverse functions.

Journal: Bioscience reports20071001

Title: Evidence that the genes encoding the melittin-related peptides in the skins of the Japanese frogs Rana sakuraii and Rana tagoi are not orthologous to bee venom melittin genes: developmental- and tissue-dependent gene expression.

Journal: Peptides20071001

Title: A dimethylmaleic acid-melittin-polylysine conjugate with reduced toxicity, pH-triggered endosomolytic activity and enhanced gene transfer potential.

Journal: The journal of gene medicine20070901

Title: [Effects of melittin on expressions of mitochondria membrane protein 7A6, cell apoptosis-related gene products Fas and Fas ligand in hepatocarcinoma cells].

Journal: Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine20070901

Title: Recombinant plasmid constructs expressing gene for antimicrobial peptide melittin for the therapy of Mycoplasma and chlamydia infections.

Journal: Bulletin of experimental biology and medicine20070901

Title: Nanoscale dewetting transition in protein complex folding.

Journal: The journal of physical chemistry. B20070802

Title: Real-time structural investigation of a lipid bilayer during its interaction with melittin using sum frequency generation vibrational spectroscopy.

Journal: Biophysical journal20070801

Title: Therapeutic application of anti-arthritis, pain-releasing, and anti-cancer effects of bee venom and its constituent compounds.

Journal: Pharmacology & therapeutics20070801

Title: Bee venom and melittin reduce proinflammatory mediators in lipopolysaccharide-stimulated BV2 microglia.

Journal: International immunopharmacology20070801

Title: Exploring the effect of cholesterol in lipid bilayer membrane on the melittin penetration mechanism.

Journal: Analytical biochemistry20070801

Title: Melittin, a major bioactive component of bee venom toxin, inhibits PDGF receptor beta-tyrosine phosphorylation and downstream intracellular signal transduction in rat aortic vascular smooth muscle cells.

Journal: Journal of toxicology and environmental health. Part A20070801

Title: A protein whose binding to Na,K-ATPase is regulated by ouabain.

Journal: Biochemistry. Biokhimiia20070801

Title: Hydrophobic and electrostatic forces control the retention of membrane peptides and proteins with an immobilised phosphatidic acid column.

Journal: Journal of chromatography. A20070713

Title: Melittin as an epithelial permeability enhancer I: investigation of its mechanism of action in Caco-2 monolayers.

Journal: Pharmaceutical research20070701

Title: Melittin as a permeability enhancer II: in vitro investigations in human mucus secreting intestinal monolayers and rat colonic mucosae.

Journal: Pharmaceutical research20070701

Title: Effect of lipid headgroup composition on the interaction between melittin and lipid bilayers.

Journal: Journal of colloid and interface science20070701

Title: The lipid dependence of melittin action investigated by dual-color fluorescence burst analysis.

Journal: Biophysical journal20070701

Title: Apis mellifera venom and melittin block neither NF-kappa B-p50-DNA interactions nor the activation of NF-kappa B, instead they activate the transcription of proinflammatory genes and the release of reactive oxygen intermediates.

Journal: Journal of immunology (Baltimore, Md. : 1950)20070701

Title: Substitution of the leucine zipper sequence in melittin with peptoid residues affects self-association, cell selectivity, and mode of action.

Journal: Biochimica et biophysica acta20070601

Title: Rationale for the design of shortened derivatives of the NK-lysin-derived antimicrobial peptide NK-2 with improved activity against Gram-negative pathogens.

Journal: The Journal of biological chemistry20070518

Title: Kinetics of channel formation in bilayer lipid membranes (BLMs) and tethered BLMs: monazomycin and melittin.

Journal: Langmuir : the ACS journal of surfaces and colloids20070508

Title: The use of solvent relaxation technique to investigate headgroup hydration and protein binding of simple and mixed phosphatidylcholine/surfactant bilayer membranes.

Journal: Biochimica et biophysica acta20070501

Title: Inhibitory effects of melittin on the production of lipopolysaccharide-induced matrix metalloproteinase 3 in human osteoarthritic chondrocytes.

Journal: Toxicon : official journal of the International Society on Toxinology20070501

Title: The response of giant phospholipid vesicles to pore-forming peptide melittin.

Journal: Biochimica et biophysica acta20070501

Title: Simultaneous measurements of K+ and calcein release from liposomes and the determination of pore size formed in a membrane.

Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry20070501

Title: Use of hecate-chorionic gonadotropin beta conjugate in therapy of lutenizing hormone receptor expressing gonadal somatic cell tumors.

Journal: Molecular and cellular endocrinology20070415

Title: The involvement of the central cholinergic system in the pressor and bradycardic effects of centrally administrated melittin in normotensive conscious rats.

Journal: Neuropeptides20070401

Title: Structural characterization of the functional regions in the archaeal protein Sso7d.

Journal: Proteins20070401

Title: Molecular cloning of the precursor polypeptide of mastoparan B and its putative processing enzyme, dipeptidyl peptidase IV, from the black-bellied hornet, Vespa basalis.

Journal: Insect molecular biology20070401

Title: Multiple functions of DOA1 in Candida albicans.

Journal: Microbiology (Reading, England)20070401

Title: Alpha,beta-dehydrophenylalanine containing cecropin-melittin hybrid peptides: conformation and activity.

Journal: Journal of peptide science : an official publication of the European Peptide Society20070401

Title: Structural and functional behavior of biologically active monomeric melittin.

Journal: Journal of molecular graphics & modelling20070301

Title: Expression of genes encoding antimicrobial and bradykinin-related peptides in skin of the stream brown frog Rana sakuraii.

Journal: Peptides20070301

Title: Activities of four frog skin-derived antimicrobial peptides (temporin-1DRa, temporin-1Va and the melittin-related peptides AR-23 and RV-23) against anaerobic bacteria.

Journal: International journal of antimicrobial agents20070301

Title: Orientation and dynamics of melittin in membranes of varying composition utilizing NBD fluorescence.

Journal: Biophysical journal20070215

Title: Multiple orientation of melittin inside a single lipid bilayer determined by combined vibrational spectroscopic studies.

Journal: Journal of the American Chemical Society20070207

Title: Allosteric inhibition of rat neuronal nitric-oxide synthase caused by interference with the binding of calmodulin to the enzyme.

Journal: Biochimica et biophysica acta20070201

Title: Defect formation of lytic peptides in lipid membranes and their influence on the thermodynamic properties of the pore environment.

Journal: Biochimica et biophysica acta20070201

Title: Melittin inhibits inflammatory target gene expression and mediator generation via interaction with IkappaB kinase.

Journal: Biochemical pharmacology20070115

Title: Phospholipase A2-independent Ca2+ entry and subsequent apoptosis induced by melittin in human MG63 osteosarcoma cells.

Journal: Life sciences20070102

Title: The membrane-induced structure of melittin is correlated with the fluidity of the lipids.

Journal: Biochimica et biophysica acta20070101

Title: Sub parts-per-million mass measurement accuracy of intact proteins and product ions achieved using a dual electrospray ionization quadrupole fourier transform ion cyclotron resonance mass spectrometer.

Journal: Journal of the American Society for Mass Spectrometry20070101

Title: Quantifying the effects of melittin on liposomes.

Journal: Biochimica et biophysica acta20070101

Title: [Interaction of melittin with ion channels of excitable membranes].

Journal: Biofizika20070101

Title: Manipulation of charge states of biopolymer ions by atmospheric pressure ion/molecule reactions implemented in an extractive electrospray ionization source.

Journal: European journal of mass spectrometry (Chichester, England)20070101

Title: Monitoring conformational changes in protein complexes using chemical cross-linking and Fourier transform ion cyclotron resonance mass spectrometry: the effect of calcium binding on the calmodulin-melittin complex.

Journal: European journal of mass spectrometry (Chichester, England)20070101

Title: [The principles of analysis on multicomponent fluorescence spectra of proteins. Temperature and pH-induced transitions in tetrameric melittin].

Journal: Biofizika20070101

Title: Roles of phospholipase A2 isoforms in swelling- and melittin-induced arachidonic acid release and taurine efflux in NIH3T3 fibroblasts.

Journal: American journal of physiology. Cell physiology20061201

Title: DNA polyplexes based on degradable oligoethylenimine-derivatives: combination with EGF receptor targeting and endosomal release functions.

Journal: Journal of controlled release : official journal of the Controlled Release Society20061128

Title: Effect of ionic strength on the organization and dynamics of membrane-bound melittin.

Journal: Biophysical chemistry20061120

Title: Diffraction-based density restraints for membrane and membrane-peptide molecular dynamics simulations.

Journal: Biophysical journal20061115

Title: [Expression of melittin tagged with green fluorescent protein and its use in hepatocellular carcinoma treatment].

Journal: Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology20061101

Title: Effect of ionic strength on folding and aggregation of the hemolytic peptide melittin in solution.

Journal: Biopolymers20061005

Title: Femtosecond studies of tryptophan fluorescence dynamics in proteins: local solvation and electronic quenching.

Journal: The journal of physical chemistry. B20060921

Title: Ca2+-independent phospholipase A2 enhances store-operated Ca2+ entry in dystrophic skeletal muscle fibers.

Journal: Journal of cell science20060915

Title: Ion/molecule reactions of cation radicals formed from protonated polypeptides via gas-phase ion/ion electron transfer.

Journal: Journal of the American Chemical Society20060913

Title: Growth arrest and apoptosis of the human hepatocellular carcinoma cell line BEL-7402 induced by melittin.

Journal: Onkologie20060901

Title: Electrochemical investigation of melittin reconstituted into a mercury-supported lipid bilayer.

Journal: Langmuir : the ACS journal of surfaces and colloids20060718

Title: Solid-state NMR investigation of the membrane-disrupting mechanism of antimicrobial peptides MSI-78 and MSI-594 derived from magainin 2 and melittin.

Journal: Biophysical journal20060701

Title: Alpha-helix formation in melittin and beta-lactoglobulin A induced by fluorinated dialcohols.

Journal: The journal of physical chemistry. B20060608

Title: The role of the central thromboxane A2 in cardiovascular effects of a phospholipase A2 activator melittin administrated intracerebroventricularly in normotensive conscious rats.

Journal: Neuropeptides20060601

Title: Peptide conformation in gas phase probed by collision-induced dissociation and its correlation to conformation in condensed phases.

Journal: Journal of the American Society for Mass Spectrometry20060601

Title: The effect of acteoside on histamine release and arachidonic acid release in RBL-2H3 mast cells.

Journal: Archives of pharmacal research20060601

Title: Melittin analogs with high lytic activity at endosomal pH enhance transfection with purified targeted PEI polyplexes.

Journal: Journal of controlled release : official journal of the Controlled Release Society20060515

Title: Melittin inhibits vascular smooth muscle cell proliferation through induction of apoptosis via suppression of nuclear factor-kappaB and Akt activation and enhancement of apoptotic protein expression.

Journal: The Journal of pharmacology and experimental therapeutics20060501

Title: Investigation of the cytotoxicity of eukaryotic and prokaryotic antimicrobial peptides in intestinal epithelial cells in vitro.

Journal: Biochemical pharmacology20060428

Title: Investigation of toroidal pore and oligomerization by melittin using transmission electron microscopy.

Journal: Biochemical and biophysical research communications20060428

Title: Discovery and characterization of a linear cyclotide from Viola odorata: implications for the processing of circular proteins.

Journal: Journal of molecular biology20060414

Title: Protein structure prediction using mutually orthogonal Latin squares and a genetic algorithm.

Journal: Biochemical and biophysical research communications20060407

Title: A novel role of phospholipase A2 in mediating spinal cord secondary injury.

Journal: Annals of neurology20060401

Title: Structural and thermodynamic aspects of the interaction between heparan sulfate and analogues of melittin.

Journal: Biochemistry20060307

Title: Secondary heat hyperalgesia induced by melittin in humans.

Journal: European journal of pain (London, England)20060201

Title: A molecular dynamics study of the bee venom melittin in aqueous solution, in methanol, and inserted in a phospholipid bilayer.

Journal: European biophysics journal : EBJ20060201

Title: Site-specific amide hydrogen exchange in melittin probed by electron capture dissociation Fourier transform ion cyclotron resonance mass spectrometry.

Journal: The Analyst20060201

Title: Cycloviolacin H4, a hydrophobic cyclotide from Viola hederaceae.

Journal: Journal of natural products20060101

Title: Effects of bee venom peptidergic components on rat pain-related behaviors and inflammation.

Journal: Neuroscience20060101

Title: Target peptide recognition by S100P protein and role of central linker region and dimer interface.

Journal: Protein and peptide letters20060101

Title: Gene transfer with poly-melittin peptides.

Journal: Bioconjugate chemistry20060101

Title: Improvement of bacterial cell selectivity of melittin by a single Trp mutation with a peptoid residue.

Journal: Protein and peptide letters20060101

Title: Multiple PLA2 isoforms regulate taurine release in NIH3T3 mouse fibroblasts.

Journal: Advances in experimental medicine and biology20060101

Title: [In-vitro activity of two hybrid synthetic peptides having antimicrobial activity against mycobacteria].

Journal: Revista Argentina de microbiologia20060101

Title: Effect of induced expression of an antimicrobial peptide melittin on Chlamydia trachomatis and Mycoplasma hominis infections in vivo.

Journal: Biochemical and biophysical research communications20051216

Title: Many-body effect of antimicrobial peptides: on the correlation between lipid's spontaneous curvature and pore formation.

Journal: Biophysical journal20051201

Title: A surface plasmon resonance sensor for substance P using gold-modified calmodulin and melittin.

Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry20051201

Title: Targeting breast and prostate cancers through their hormone receptors.

Journal: Biology of reproduction20051101

Title: Morphological behavior of lipid bilayers induced by melittin near the phase transition temperature.

Journal: Biophysical journal20051101

Title: Quantification of the effects of melittin on liposome structure.

Journal: Biochemical Society transactions20051101

Title: Membrane perturbation effects of peptides derived from the N-termini of unprocessed prion proteins.

Journal: Biochimica et biophysica acta20051015

Title: Preparation and characterization of melittin-loaded poly (DL-lactic acid) or poly (DL-lactic-co-glycolic acid) microspheres made by the double emulsion method.

Journal: Journal of controlled release : official journal of the Controlled Release Society20051003

Title: C- versus N-terminally linked melittin-polyethylenimine conjugates: the site of linkage strongly influences activity of DNA polyplexes.

Journal: The journal of gene medicine20051001

Title: Binding and folding of melittin in the presence of ganglioside GM1 micelles.

Journal: Journal of biomolecular structure & dynamics20051001

Title: Effect of hexafluoroisopropanol alcohol on the structure of melittin: a molecular dynamics simulation study.

Journal: Protein science : a publication of the Protein Society20051001

Title: Anti-inflammatory effect of germanium-concentrated yeast against paw oedema is related to the inhibition of arachidonic acid release and prostaglandin E production in RBL 2H3 cells.

Journal: Autonomic & autacoid pharmacology20051001

Title: [Synthesis of peptide fragment of melittin and the function of rheumatoid arthritis cure].

Journal: Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi20051001

Title: Ultrafast hydration dynamics in melittin folding and aggregation: helix formation and tetramer self-assembly.

Journal: The journal of physical chemistry. B20050908

Title: Observation of a dewetting transition in the collapse of the melittin tetramer.

Journal: Nature20050901

Title: Synthesis and preliminary evaluation of poly(amidoamine)-melittin conjugates as endosomolytic polymers and/or potential anticancer therapeutics.

Journal: International journal of pharmaceutics20050826

Title: Evaluation and optimization of electron capture dissociation efficiency in fourier transform ion cyclotron resonance mass spectrometry.

Journal: Journal of the American Society for Mass Spectrometry20050701

Title: Pathogen-induced expression of a cecropin A-melittin antimicrobial peptide gene confers antifungal resistance in transgenic tobacco.

Journal: Journal of experimental botany20050601

Title: Activation of spinal extracellular signaling-regulated kinases by intraplantar melittin injection.

Journal: Neuroscience letters20050601

Title: Targeted ablation of prostate carcinoma cells through LH receptor using Hecate-CGbeta conjugate: functional characteristic and molecular mechanism of cell death pathway.

Journal: Experimental biology and medicine (Maywood, N.J.)20050601

Title: A novel targeted therapy of Leydig and granulosa cell tumors through the luteinizing hormone receptor using a hecate-chorionic gonadotropin beta conjugate in transgenic mice.

Journal: Neoplasia (New York, N.Y.)20050501

Title: Cholesterol inhibits the lytic activity of melittin in erythrocytes.

Journal: Chemistry and physics of lipids20050401

Title: A generalized Born formalism for heterogeneous dielectric environments: application to the implicit modeling of biological membranes.

Journal: The Journal of chemical physics20050322

Title: Inhibition sites in F1-ATPase from bovine heart mitochondria.

Journal: The Biochemical journal20050315

Title: Melittin-induced bilayer leakage depends on lipid material properties: evidence for toroidal pores.

Journal: Biophysical journal20050301

Title: Deletion of two C-terminal Gln residues of 12-26-residue fragment of melittin improves its antimicrobial activity.

Journal: Peptides20050301

Title: Understanding the energetics of helical peptide orientation in membranes.

Journal: Proteins20050301

Title: Implicit solvent simulations of peptide interactions with anionic lipid membranes.

Journal: Proteins20050215

Title: Identification and optimization of an antimicrobial peptide from the ant venom toxin pilosulin.

Journal: Archives of biochemistry and biophysics20050215

Title: Hydroxyl radical probe of the calmodulin-melittin complex interface by electrospray ionization mass spectrometry.

Journal: Journal of the American Society for Mass Spectrometry20050201

Title: Inhibitory effect of recombinant adenovirus carrying melittin gene on hepatocellular carcinoma.

Journal: Annals of oncology : official journal of the European Society for Medical Oncology20050101

Title: Similarities of cow mammary gland cytosolic 21-kDa protein, the substrate for protein kinase C, to the 20-kDa myosin light chain from smooth muscle.

Journal: The Journal of veterinary medical science20050101

Title: Phospholipase A2 activation by melittin enhances spontaneous glutamatergic excitatory transmission in rat substantia gelatinosa neurons.

Journal: Neuroscience20050101

Title: [The component analysis of tryptophan fluorescence spectra of melittin during its oligomerization].

Journal: Biofizika20050101

Title: Melittin-induced membrane permeability: a nonosmotic mechanism of cell death.

Journal: In vitro cellular & developmental biology. Animal20050101

Title: Dissection of antibacterial and toxic activity of melittin: a leucine zipper motif plays a crucial role in determining its hemolytic activity but not antibacterial activity.

Journal: The Journal of biological chemistry20041231

Title: [Anti-hepatocarcinoma effect of recombinant adenovirus carrying melittin gene].

Journal: Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology20041201

Title: Influence of the lipid composition on the kinetics of concerted insertion and folding of melittin in bilayers.

Journal: Biochimica et biophysica acta20041117

Title: Effect of micellar charge on the conformation and dynamics of melittin.

Journal: European biophysics journal : EBJ20041101

Title: Dynamic structure of vesicle-bound melittin in a variety of lipid chain lengths by solid-state NMR.

Journal: Biophysical journal20041101

Title: Increased sensitivity of early apoptotic cells to complement-mediated lysis.

Journal: European journal of immunology20041101

Title: Antiarthritic effect of bee venom: inhibition of inflammation mediator generation by suppression of NF-kappaB through interaction with the p50 subunit.

Journal: Arthritis and rheumatism20041101

Title: SERCA structural dynamics induced by ATP and calcium.

Journal: Biochemistry20041012

Title: Influence of lipid chain unsaturation on membrane-bound melittin: a fluorescence approach.

Journal: Biochimica et biophysica acta20041011

Title: Interaction of melittin with membrane cholesterol: a fluorescence approach.

Journal: Biophysical journal20041001

Title: Expression of the melittin gene of Apis cerana cerana in Escherichia coli.

Journal: Protein expression and purification20040901

Title: Antibiotic activity and synergistic effect of antimicrobial peptide against pathogens from a patient with gallstones.

Journal: Biochemical and biophysical research communications20040827

Title: Melittin selectively activates capsaicin-sensitive primary afferent fibers.

Journal: Neuroreport20040806

Title: [The induced apoptosis of recombinant adenovirus carrying melittin gene for hepatocellular carcinoma cell].

Journal: Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology20040801

Title: The 2004 Biophysical Society-Avanti Award in Lipids address: roles of bilayer structure and elastic properties in peptide localization in membranes.

Journal: Chemistry and physics of lipids20040701

Title: Evaluation of different combinations of gated trapping, RF-only mode and trap compensation for in-field MALDI Fourier transform mass spectrometry.

Journal: Journal of the American Society for Mass Spectrometry20040701

Title: In vitro activity and killing effect of the synthetic hybrid cecropin A-melittin peptide CA(1-7)M(2-9)NH(2) on methicillin-resistant nosocomial isolates of Staphylococcus aureus and interactions with clinically used antibiotics.

Journal: Diagnostic microbiology and infectious disease20040701

Title: Structure and solvation of melittin in hexafluoroacetone/water.

Journal: Biopolymers20040615

Title: Biodistributions of intact monoclonal antibodies and fragments of BLCA-38, a new prostate cancer directed antibody.

Journal: Cancer immunology, immunotherapy : CII20040601

Title: Melittin-induced changes in thylakoid membranes: particle electrophoresis and light scattering study.

Journal: Biophysical chemistry20040601

Title: A receptor-like kinase from Arabidopsis thaliana is a calmodulin-binding protein.

Journal: The Biochemical journal20040501

Title: Cytotoxic properties of immunoconjugates containing melittin-like peptide 101 against prostate cancer: in vitro and in vivo studies.

Journal: Cancer immunology, immunotherapy : CII20040501

Title: Comparative analysis of GFP(UV)-beta1,3-N-acetylglucosaminyltransferase 2 production in two insect-cell-based expression systems.

Journal: Protein expression and purification20040501

Title: Melittin as model system for probing interactions between proteins and cyclodextrins.

Journal: Proteins20040501

Title: Structure and solvation of melittin in 1,1,1,3,3,3-hexafluoro-2-propanol/water.

Journal: Biophysical journal20040501

Title: Induced expression of the antimicrobial peptide melittin inhibits experimental infection by Mycoplasma gallisepticum in chickens.

Journal: Microbes and infection20040501

Title: [Effect of melittin on apoptosis and necrosis of U2 OS cells].

Journal: Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine20040501

Title: Mechanism of Ca2+ activation of the NADPH oxidase 5 (NOX5).

Journal: The Journal of biological chemistry20040430

Title: Mapping the topology and determination of a low-resolution three-dimensional structure of the calmodulin-melittin complex by chemical cross-linking and high-resolution FTICRMS: direct demonstration of multiple binding modes.

Journal: Biochemistry20040427

Title: Growth repression in diethylstilbestrol/dimethylbenz[a]anthracene-induced rat mammary gland tumor using Hecate-CGbeta conjugate.

Journal: Experimental biology and medicine (Maywood, N.J.)20040401

Title: Conformation of the cecropin-melittin hybrid, cecropin A(1-8)-melittin (1-18) antibacterial Peptide.

Journal: Protein and peptide letters20040401

Title: Energetics of pore formation induced by membrane active peptides.

Journal: Biochemistry20040330

Title: Melittin induces both time-dependent aggregation and inhibition of Na,K-ATPase from duck salt glands however these two processes appear to occur independently.

Journal: Biochimica et biophysica acta20040309

Title: GTP-binding protein-independent potentiation by mastoparan of IL-1beta-induced nitric oxide release from insulin-secreting HIT-T15 cells.

Journal: Apoptosis : an international journal on programmed cell death20040301

Title: Gene transfer with modified polyethylenimines.

Journal: The journal of gene medicine20040201

Title: Antinematodal activity and the mechanism of the antimicrobial peptide, HP (2-20), against Caenorhabditis elegans.

Journal: Biotechnology letters20040201

Title: PLA2 and secondary metabolites of arachidonic acid control filopodial behavior in neuronal growth cones.

Journal: Cell motility and the cytoskeleton20040101

Title: Membrane binding, structure, and localization of cecropin-mellitin hybrid peptides: a site-directed spin-labeling study.

Journal: Biophysical journal20040101

Title: Excitation of ions by high-harmonic frequency components in Paul and Penning traps and ion guides. I. Selective simultaneous dipolar excitation of high charge states with clipped sinusoidal and non-harmonic waveforms in a linear quadrupole ion guide.

Journal: European journal of mass spectrometry (Chichester, England)20040101

Title: Altered pain-related behaviors and spinal neuronal responses produced by s.c. injection of melittin in rats.

Journal: Neuroscience20040101

Title: Temperature dependence of the melittin folding equilibrium studied by means of fluorescence excitation spectra.

Journal: Journal of fluorescence20040101

Title: Conformational analysis of melittin in solution phase: vibrational circular dichroism study.

Journal: Biopolymers20031201

Title: Individual substitution analogs of Mel(12-26), melittin's C-terminal 15-residue peptide: their antimicrobial and hemolytic actions.

Journal: FEBS letters20031106

Title: An implicit membrane generalized born theory for the study of structure, stability, and interactions of membrane proteins.

Journal: Biophysical journal20031101

Title: Bilayer localization of membrane-active peptides studied in biomimetic vesicles by visible and fluorescence spectroscopies.

Journal: European journal of biochemistry20031101

Title: Protein in sugar films and in glycerol/water as examined by infrared spectroscopy and by the fluorescence and phosphorescence of tryptophan.

Journal: Biophysical journal20030901

Title: Comparative activities of cecropin A, melittin, and cecropin A-melittin peptide CA(1-7)M(2-9)NH2 against multidrug-resistant nosocomial isolates of Acinetobacter baumannii.

Journal: Peptides20030901

Title: Irreversible binding and activity control of the 1,2-diacylglycerol 3-glucosyltransferase from Acholeplasma laidlawii at an anionic lipid bilayer surface.

Journal: Biochemistry20030819

Title: Effective energy function for proteins in lipid membranes.

Journal: Proteins20030801

Title: Infrared multiphoton dissociation with a hollow fiber waveguide.

Journal: Analytical chemistry20030801

Title: Regulatory interaction of sodium channel IQ-motif with calmodulin C-terminal lobe.

Journal: Biochemical and biophysical research communications20030725

Title: A melittin-related peptide from the skin of the Japanese frog, Rana tagoi, with antimicrobial and cytolytic properties.

Journal: Biochemical and biophysical research communications20030627

Title: Reactive oxygen species are important mediators of taurine release from skeletal muscle cells.

Journal: American journal of physiology. Cell physiology20030601

Title: Evidence for membrane thinning effect as the mechanism for peptide-induced pore formation.

Journal: Biophysical journal20030601

Title: [Cloning and comparative analysis of the venom prepromelittin genes from four wasp species].

Journal: Yi chuan xue bao = Acta genetica Sinica20030601

Title: Quantification of protein-ligand interactions by mass spectrometry, titration, and H/D exchange: PLIMSTEX.

Journal: Journal of the American Chemical Society20030507

Title: Effects of sphingomyelin on melittin pore formation.

Journal: Biochimica et biophysica acta20030502

Title: The antibiotic activity of cationic linear amphipathic peptides: lessons from the action of leucine/lysine copolymers on bacteria of the class Mollicutes.

Journal: European journal of biochemistry20030501

Title: A novel approach of targeted ablation of mammary carcinoma cells through luteinizing hormone receptors using Hecate-CGbeta conjugate.

Journal: Breast cancer research and treatment20030501

Title: Differential effects of raloxifene, tamoxifen and fulvestrant on a murine mammary carcinoma.

Journal: Breast cancer research and treatment20030501

Title: Interactions of mouse Paneth cell alpha-defensins and alpha-defensin precursors with membranes. Prosegment inhibition of peptide association with biomimetic membranes.

Journal: The Journal of biological chemistry20030418

Title: Impact of infection with recombinant adenovirus carrying melittin gene on CD54 expression in HepG2 cells.

Journal: Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA20030401

Title: Functional characterization of bacterial signal peptide OmpA in a baculovirus-mediated expression system.

Journal: Cell structure and function20030401

Title: D-amino acid residues in peptides and proteins.

Journal: Proteins20030301

Title: Membrane disrupting lytic peptide conjugates destroy hormone dependent and independent breast cancer cells in vitro and in vivo.

Journal: Breast cancer research and treatment20030301

Title: Reactive oxygen species regulate swelling-induced taurine efflux in NIH3T3 mouse fibroblasts.

Journal: The Journal of membrane biology20030301

Title: A comparison of hyperalgesia and neurogenic inflammation induced by melittin and capsaicin in humans.

Journal: Neuroscience letters20030213

Title: Label-free chiral detection of melittin binding to a membrane.

Journal: Journal of the American Chemical Society20030205

Title: Lipopolysaccharides in bacterial membranes act like cholesterol in eukaryotic plasma membranes in providing protection against melittin-induced bilayer lysis.

Journal: Biochemistry20030204

Title: Hybrid global optimization algorithms for protein structure prediction: alternating hybrids.

Journal: Biophysical journal20030201

Title: Nod factors activate both heterotrimeric and monomeric G-proteins in Vigna unguiculata (L.) Walp.

Journal: Planta20030201

Title: Exploring peptide membrane interaction using surface plasmon resonance: differentiation between pore formation versus membrane disruption by lytic peptides.

Journal: Biochemistry20030121

Title: A matrix metalloproteinase 2 cleavable melittin/avidin conjugate specifically targets tumor cells in vitro and in vivo.

Journal: International journal of oncology20030101

Title: Endosomolysis by masking of a membrane-active agent (EMMA) for cytoplasmic release of macromolecules.

Journal: Bioconjugate chemistry20030101

Title: Bilayer interfacial properties modulate the binding of amphipathic peptides.

Journal: Chemistry and physics of lipids20030101

Title: Bimodal regulatory effect of melittin and phospholipase A2-activating protein on human type II secretory phospholipase A2.

Journal: Cell biology international20030101

Title: Adjuvant action of melittin following intranasal immunisation with tetanus and diphtheria toxoids.

Journal: Journal of drug targeting20030101

Title: Ionization energies of multiply protonated polypeptides obtained by tandem ionization in Fourier transform mass spectrometers.

Journal: Journal of mass spectrometry : JMS20021101

Title: Antibacterial and antifungal properties of alpha-helical, cationic peptides in the venom of scorpions from southern Africa.

Journal: European journal of biochemistry20021001

Title: Sequence requirements for the activity of membrane-active peptides.

Journal: The journal of peptide research : official journal of the American Peptide Society20021001

Title: Solid-state NMR conformational studies of a melittin-inhibitor complex.

Journal: European biophysics journal : EBJ20020901

Title: Inhibition by melittin of phosphorylation by protein kinase C of annexin I from cow mammary gland.

Journal: The Journal of veterinary medical science20020901

Title: Cloaking cytolytic peptides for liposome-based detection and potential drug delivery.

Journal: Biochimica et biophysica acta20020819

Title: Multiple ion isolation applications in FT-ICR MS: exact-mass MSn internal calibration and purification/interrogation of protein-drug complexes.

Journal: Analytical chemistry20020801

Title: Conformational and thermodynamic properties of peptide binding to the human S100P protein.

Journal: Protein science : a publication of the Protein Society20020601

Title: Role of melittin-like region within phospholipase A(2)-activating protein in biological function.

Journal: Toxicon : official journal of the International Society on Toxinology20020501

Title: Structure and activity of D-Pro14 melittin.

Journal: Journal of protein chemistry20020501

Title: Cation- and peptide-binding properties of human calmodulin-like skin protein.

Journal: Biochemistry20020430

Title: Effects of a lytic peptide conjugated to beta HCG on ovarian cancer: studies in vitro and in vivo.

Journal: Gynecologic oncology20020401

Title: Melittin-GM1 interaction: a model for a side-by-side complex.

Journal: Biochemical and biophysical research communications20020329

Title: The presence of PEG-lipids in liposomes does not reduce melittin binding but decreases melittin-induced leakage.

Journal: Biochimica et biophysica acta20020201

Title: Induced expression of melittin, an antimicrobial peptide, inhibits infection by Chlamydia trachomatis and Mycoplasma hominis in a HeLa cell line.

Journal: International journal of antimicrobial agents20020201

Title: Second derivative fluorescence spectroscopy of tryptophan in proteins.

Journal: Journal of biochemical and biophysical methods20020104

Title: Arachidonic acid release from rat Leydig cells: the involvement of G protein, phospholipase A2 and regulation of cAMP production.

Journal: The Journal of endocrinology20020101

Title: [Interaction of local anesthetics with model ion channels].

Journal: Biofizika20020101

Title: Biphasic vasomotor reflex responses of the hand skin following intradermal injection of melittin into the forearm skin.

Journal: European journal of pain (London, England)20020101

Title: Melittin enables efficient vesicular escape and enhanced nuclear access of nonviral gene delivery vectors.

Journal: The Journal of biological chemistry20011214

Title: Delayed oxidant-induced cell death involves activation of phospholipase A2.

Journal: FEBS letters20011214

Title: Structure of melittin bound to phospholipid micelles studied using hydrogen-deuterium exchange and electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry.

Journal: Journal of the American Society for Mass Spectrometry20011201

Title: Measurement of the affinity of melittin for zwitterionic and anionic membranes using immobilized lipid biosensors.

Journal: The journal of peptide research : official journal of the American Peptide Society20011201

Title: Solid-state NMR structure determination of melittin in a lipid environment.

Journal: Biophysical journal20011101

Title: 'Detergent-like' permeabilization of anionic lipid vesicles by melittin.

Journal: Biochimica et biophysica acta20011001

Title: Interaction of Na,K-ATPase catalytic subunit with cellular proteins and other endogenous regulators.

Journal: Biochemistry. Biokhimiia20011001

Title: Barrel-stave model or toroidal model? A case study on melittin pores.

Journal: Biophysical journal20010901

Title: Membrane fusion between liposomes composed of acidic phospholipids and neutral phospholipids induced by melittin: a differential scanning calorimetric study.

Journal: Journal of biochemistry20010901

Title: Effects of temporins on molecular dynamics and membrane permeabilization in lipid vesicles.

Journal: The journal of peptide research : official journal of the American Peptide Society20010901

Title: Self-association and membrane-binding behavior of melittins containing trifluoroleucine.

Journal: Journal of the American Chemical Society20010801

Title: Effects of melittin on isolated papillary muscles of guinea pig.

Journal: Acta pharmacologica Sinica20010801

Title: Effects of phospholipase A(2) activating peptides upon GTP-binding protein-evoked adrenocorticotrophin secretion.

Journal: European journal of pharmacology20010727

Title: Cytolytic peptides induce biphasic permeability changes in mammalian cell membranes.

Journal: Journal of immunological methods20010601

Title: Mechanisms of regulation of agonist efficacy at the 5-HT(1A) receptor by phospholipid-derived signaling components.

Journal: The Journal of pharmacology and experimental therapeutics20010601

Title: The effect of cyclization of magainin 2 and melittin analogues on structure, function, and model membrane interactions: implication to their mode of action.

Journal: Biochemistry20010529

Title: Analysis of antimicrobial peptide interactions with hybrid bilayer membrane systems using surface plasmon resonance.

Journal: Biochimica et biophysica acta20010502

Title: Mechanisms of tryptophan fluorescence shifts in proteins.

Journal: Biophysical journal20010501

Title: Melittin exerts multiple effects on the release of free fatty acids from L1210 cells: lack of selective activation of phospholipase A2 by melittin.

Journal: Archives of biochemistry and biophysics20010501

Title: Use of trinitrophenylation for quantification of protease and peptidase activities.

Journal: Biochemistry. Biokhimiia20010501

Title: Energetics of target peptide binding by calmodulin reveals different modes of binding.

Journal: The Journal of biological chemistry20010427

Title: Peptide leucine arginine, a potent immunomodulatory peptide isolated and structurally characterized from the skin of the Northern Leopard frog, Rana pipiens.

Journal: The Journal of biological chemistry20010330

Title: Rapid down regulation of pyroglutamyl peptidase II activity by arachidonic acid in primary cultures of adenohypophyseal cells.

Journal: Life sciences20010316

Title: [Cloning and expression of a synthetic gene encoding magainin-melittin hybrid peptide in Escherichia coli and studies on its antibacterial activity].

Journal: Sheng wu gong cheng xue bao = Chinese journal of biotechnology20010301

Title: Inhibitory effect of melittin on Na+,K+-ATPase from guinea pig myocardial mitochondria.

Journal: Acta pharmacologica Sinica20010301

Title: Prostaglandin levels in stimulated macrophages are controlled by phospholipase A2-activating protein and by activation of phospholipase C and D.

Journal: The Journal of biological chemistry20010223

Title: Structure, location, and lipid perturbations of melittin at the membrane interface.

Journal: Biophysical journal20010201

Title: Pressure-dependent changes in the structure of the melittin alpha-helix determined by NMR.

Journal: Journal of biomolecular NMR20010201

Title: The lipid charge density at the bilayer surface modulates the effects of melittin on membranes.

Journal: Chemistry and physics of lipids20010201

Title: Paramecium calmodulin mutants defective in ion channel regulation associate with melittin in the absence of calcium but require it for tertiary collapse.

Journal: Biochemistry20010130

Title: Polycations induce the release of soluble intermembrane mitochondrial proteins.

Journal: Biochimica et biophysica acta20010119

Title: Membrane molecule reorientation in an electric field recorded by attenuated total reflection Fourier-transform infrared spectroscopy.

Journal: Biophysical journal20010101

Title: [Cytotoxic activity of melittin expressed by recombinant vectors in Acholeplasma laidlawii and Mycoplasma hominis cells].

Journal: Genetika20010101

Title: A cylindrical capacitor ionization source: droplet generation and controlled charge reduction for mass spectrometry.

Journal: Rapid communications in mass spectrometry : RCM20010101

Title: Effect of controlled expression of the melittin gene on infection caused by Mycoplasma hominis in cell culture.

Journal: Doklady. Biochemistry and biophysics20010101

Title: Stimulation by melittin of Na+-Ca2+ exchange current in ventricular myocytes of guinea pigs.

Journal: Acta pharmacologica Sinica20010101

Title: [Intensification of the interaction of IgG with C1q in the presence of melittin as a possible reason for anaphylaxis under the effect of bee venom].

Journal: Ukrains'kyi biokhimichnyi zhurnal (1999 )20010101

Title: Pyridoxal-phosphate-6-azophenyl-2',4'-disulfonate (PPADS), a putative P2Y(1) receptor antagonist, blocks signaling at a site distal to the receptor in Madin-Darby canine kidney-D(1) cells.

Journal: The Journal of pharmacology and experimental therapeutics20000101

Title: Antimicrobial peptides melittin and cecropin inhibit replication of human immunodeficiency virus 1 by suppressing viral gene expression.

Journal: The Journal of general virology19980401

Title: Expression of antimicrobial peptides has an antitumour effect in human cells.

Journal: Biochemical and biophysical research communications19980126

Title: Synergism between mellitin and phospholipase A2 from bee venom: apparent activation by intervesicle exchange of phospholipids.

Journal: Biochemistry19970401

Title: Enhancement of stress-induced synthesis of hsp27 and alpha B crystallin by modulators of the arachidonic acid cascade.

Journal: Journal of cellular physiology19960201

Title: The amino-terminal peptide of HIV-1 glycoprotein 41 lyses human erythrocytes and CD4+ lymphocytes.

Journal: Biochimica et biophysica acta19920825

Title: Steiner MR, et al. Responses of purified phospholipases A2 to phospholipase A2 activating protein (PLAP) and Melittin. Biochim Biophys Acta. 1993 Feb 10;1166(1):124-30.

Title: Alonezi S, et al. Metabolomic Profiling of the Effects of Melittin on Cisplatin Resistant and Cisplatin Sensitive Ovarian Cancer Cells Using Mass Spectrometry and Biolog Microarray Technology. Metabolites. 2016 Oct 13;6(4). pii: E35.

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