Home Sulfonamines 2386-58-5
2386-58-5,MFCD00051751
Catalog No.:AA00BDWW

2386-58-5 | ethenesulfonamide

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100mg
95%
in stock  
$50.00   $35.00
- +
250mg
95%
in stock  
$61.00   $43.00
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1g
95%
in stock  
$240.00   $168.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00BDWW
Chemical Name:
ethenesulfonamide
CAS Number:
2386-58-5
Molecular Formula:
C2H5NO2S
Molecular Weight:
107.1316
MDL Number:
MFCD00051751
SMILES:
C=CS(=O)(=O)N
Properties
Computed Properties
 
Complexity:
128  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
6  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
1  
XLogP3:
-0.6  

Downstream Synthesis Route

[1]Matlack[JournalofOrganicChemistry,1958,vol.23,p.729]

[1]Lonchambon,Georges;Delacroix,Alain;Petit,Jacques;Lecomte,Patrice[BulletindelaSocieteChimiquedeFrance,1981,vol.2,#1-2,p.71-74]

[2]CurrentPatentAssignee:CARDIOTHERAPEUTICS-WO2018/165718,2018,A1Locationinpatent:Page/Pagecolumn76

[3]Bonnar,James;Dixon,Ian;Evison,BennyJ.;Kelly,GrahamE.;Kumar,Sanjay;Lambert,Gilles;Nativel,Brice;Palmer,JamesT.;Parmar,Jasneet;Rathi,AnujKumar;Suchowerska,AlexandraK.;Tang,Wei;Teng,Yanfen;Treutlein,Herbert;Wang,Jie;Xu,Yanfeng;Zeng,Jun;Zhu,Qing;Chemello,Kévin[Bioorganicandmedicinalchemistry,2020,vol.28,#6]

[4]CurrentPatentAssignee:C.H.BoehringerSohnAG&Co.KG-WO2008/147697,2008,A1Locationinpatent:Page/Pagecolumn161

[5]CurrentPatentAssignee:SPEROTHERAPEUTICSINC-WO2016/112088,2016,A1Locationinpatent:Paragraph0738

[6]Matlack[JournalofOrganicChemistry,1958,vol.23,p.729]

[7]Giorgetti,J.-P.[BulletindelaSocieteChimiquedeFrance,1971,#10,p.3600-3603]

[8]CurrentPatentAssignee:USVLTD.-WO2009/118753,2009,A2Locationinpatent:Page/Pagecolumn32

[9]CurrentPatentAssignee:PEKINGUNIVERSITY-EP2562157,2013,A1Locationinpatent:Paragraph0053;0054

[10]CurrentPatentAssignee:PEKINGUNIVERSITY-US2013/136794,2013,A1Locationinpatent:Paragraph0112;0113

[11]CurrentPatentAssignee:CENTRALGLASSCOLTD-US2020/115401,2020,A1Locationinpatent:Paragraph0269

[12]CurrentPatentAssignee:Novartis(w/oSandoz);NOVARTISAG-WO2020/58913,2020,A1Locationinpatent:Page/Pagecolumn66-67

[1]Matlack[JournalofOrganicChemistry,1958,vol.23,p.729]

[1]LeBerre,A.;Porte,C.[BulletindelaSocieteChimiquedeFrance,1978,vol.<II>,p.602-608]

[1]LeBerre,A.;Porte,C.[BulletindelaSocieteChimiquedeFrance,1978,vol.<II>,p.602-608]

Literature

Title: Synthesis of a unique isoindoline/tetrahydroisoquinoline-based tricyclic sultam library utilizing a Heck-aza-Michael strategy.

Journal: ACS combinatorial science 20120312

Title: Automated synthesis of a 184-member library of thiadiazepan-1,1-dioxide-4-ones.

Journal: ACS combinatorial science 20110509

Title: In vitro and in vivo studies of the trypanocidal properties of WRR-483 against Trypanosoma cruzi.

Journal: PLoS neglected tropical diseases 20100901

Title: Designed semisynthetic protein inhibitors of Ub/Ubl E1 activating enzymes.

Journal: Journal of the American Chemical Society 20100217

Title: 'Click, click, cyclize': a DOS approach to sultams utilizing vinyl sulfonamide linchpins.

Journal: Organic letters 20090205

Title: A versatile synthesis of 2,4-substituted oxazoles.

Journal: Chemical communications (Cambridge, England) 20080828

Title: Indium-mediated tandem radical addition-cyclization-trap reactions in aqueous media.

Journal: Organic letters 20031016

Title: Evaluation of vinylsulfamides as sulfhydryl selective alkylation reagents in protein modification.

Journal: Bioorganic & medicinal chemistry letters 20030210

Title: omega-(Imidazol-4-yl)alkane-1-sulfonamides: a new series of potent histamine H(3) receptor antagonists.

Journal: Bioorganic & medicinal chemistry 20020201

Title: Synthesis and structure-activity relationships in a series of ethenesulfonamide derivatives, a novel class of endothelin receptor antagonists.

Journal: Chemical & pharmaceutical bulletin 20011201

Title: Ethenesulfonamide and ethanesulfonamide derivatives, a novel class of orally active endothelin-A receptor antagonists.

Journal: Bioorganic & medicinal chemistry 20011101

Title: Potent second generation vinyl sulfonamide inhibitors of the trypanosomal cysteine protease cruzain.

Journal: Bioorganic & medicinal chemistry letters 20011022

Title: Ethenesulfonamide derivatives, a novel class of orally active endothelin-A receptor antagonists.

Journal: Chemical & pharmaceutical bulletin 20010501

Title: Tyrosine kinase inhibitors. 18. 6-Substituted 4-anilinoquinazolines and 4-anilinopyrido[3,4-d]pyrimidines as soluble, irreversible inhibitors of the epidermal growth factor receptor.

Journal: Journal of medicinal chemistry 20010201

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