Title: Efficiency and Safety of CRAC Inhibitors in Human Rheumatoid Arthritis Xenograft Models.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20170901
Title: Store-operated CRAC channel inhibitors: opportunities and challenges.
Journal: Future medicinal chemistry 20160501
Title: Store-operated CRAC channels regulate gene expression and proliferation in neural progenitor cells.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20140702
Title: Transient receptor potential canonical 3 (TRPC3) is required for IgG immune complex-induced excitation of the rat dorsal root ganglion neurons.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20120711
Title: The mechanism of injury-induced intracellular calcium concentration oscillations in the endothelium of excised rat aorta.
Journal: Journal of vascular research 20120101
Title: Vascular endothelial growth factor stimulates endothelial colony forming cells proliferation and tubulogenesis by inducing oscillations in intracellular Ca2+ concentration.
Journal: Stem cells (Dayton, Ohio) 20111101
Title: Store-operated calcium entry and non-capacitative calcium entry have distinct roles in thrombin-induced calcium signalling in human platelets.
Journal: Cell calcium 20111001
Title: Structural requirements for the inhibition of calcium mobilization and mast cell activation by the pyrazole derivative BTP2.
Journal: The international journal of biochemistry & cell biology 20110801
Title: Overexpression of transient receptor potential canonical type 1 (TRPC1) alters both store operated calcium entry and depolarization-evoked calcium signals in C2C12 cells.
Journal: Cell calcium 20110601
Title: Store-operated Ca(2+) entry (SOCE) contributes to normal skeletal muscle contractility in young but not in aged skeletal muscle.
Journal: Aging 20110601
Title: Gβγ subunits inhibit Epac-induced melanoma cell migration.
Journal: BMC cancer 20110101
Title: Store-operated Ca(2+) entry is expressed in human endothelial progenitor cells.
Journal: Stem cells and development 20101201
Title: Mechanism for carbachol-induced secretion of lacritin in cultured monkey lacrimal acinar cells.
Journal: Investigative ophthalmology & visual science 20100901
Title: Role of TRPC3 channels in ATP-induced Ca2+ signaling in principal cells of the inner medullary collecting duct.
Journal: American journal of physiology. Renal physiology 20100701
Title: Inhibition of TRPC6 channel activity contributes to the antihypertrophic effects of natriuretic peptides-guanylyl cyclase-A signaling in the heart.
Journal: Circulation research 20100625
Title: Knockdown of stromal interaction molecule 1 attenuates hepatocyte growth factor-induced endothelial progenitor cell proliferation.
Journal: Experimental biology and medicine (Maywood, N.J.) 20100301
Title: Characterization of YM-58483/BTP2, a novel store-operated Ca2+ entry blocker, on T cell-mediated immune responses in vivo.
Journal: International immunopharmacology 20081220
Title: Novel potent and selective Ca2+ release-activated Ca2+ (CRAC) channel inhibitors. Part 3: synthesis and CRAC channel inhibitory activity of 4'-[(trifluoromethyl)pyrazol-1-yl]carboxanilides.
Journal: Bioorganic & medicinal chemistry 20081101
Title: The suppressive effects of YM-58483/BTP-2, a store-operated Ca2+ entry blocker, on inflammatory mediator release in vitro and airway responses in vivo.
Journal: Pulmonary pharmacology & therapeutics 20080101
Title: Store-operated calcium entry mediates intracellular alkalinization, ERK1/2, and Akt/PKB phosphorylation in bovine neutrophils.
Journal: Journal of leukocyte biology 20071101
Title: YM-58483, a selective CRAC channel inhibitor, prevents antigen-induced airway eosinophilia and late phase asthmatic responses via Th2 cytokine inhibition in animal models.
Journal: European journal of pharmacology 20070410
Title: Potent inhibition of store-operated Ca2+ influx and superoxide production in HL60 cells and polymorphonuclear neutrophils by the pyrazole derivative BTP2.
Journal: Journal of leukocyte biology 20070401
Title: Canonical transient receptor potential channels promote cardiomyocyte hypertrophy through activation of calcineurin signaling.
Journal: The Journal of biological chemistry 20061103
Title: A store-operated Ca(2+) influx pathway in the bag cell neurons of Aplysia.
Journal: Journal of neurophysiology 20061101
Title: Basiliolides, a class of tetracyclic C19 dilactones from Thapsia garganica, release Ca(2+) from the endoplasmic reticulum and regulate the activity of the transcription factors nuclear factor of activated T cells, nuclear factor-kappaB, and activator protein 1 in T lymphocytes.
Journal: The Journal of pharmacology and experimental therapeutics 20061001
Title: Ca2+-independent phospholipase A2 enhances store-operated Ca2+ entry in dystrophic skeletal muscle fibers.
Journal: Journal of cell science 20060915
Title: A pyrazole derivative potently inhibits lymphocyte Ca2+ influx and cytokine production by facilitating transient receptor potential melastatin 4 channel activity.
Journal: Molecular pharmacology 20060401
Title: Cell proliferation depends on mitochondrial Ca2+ uptake: inhibition by salicylate.
Journal: The Journal of physiology 20060215
Title: TRPV6 potentiates calcium-dependent cell proliferation.
Journal: Cell calcium 20060201
Title: [TRP channels as targets for novel calcium antagonists].
Journal: Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20051101
Title: A functional link between store-operated and TRPC channels revealed by the 3,5-bis(trifluoromethyl)pyrazole derivative, BTP2.
Journal: The Journal of biological chemistry 20050325
Title: Potent inhibition of Ca2+ release-activated Ca2+ channels and T-lymphocyte activation by the pyrazole derivative BTP2.
Journal: The Journal of biological chemistry 20040326
Title: A pyrazole derivative, YM-58483, potently inhibits store-operated sustained Ca2+ influx and IL-2 production in T lymphocytes.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20030501
Title: Qi Z, et al. The Central Analgesic Mechanism of YM-58483 in Attenuating Neuropathic Pain in Rats. Cell Mol Neurobiol. 2016 Oct;36(7):1035-43
Title: Ohga K, et al. Characterization of YM-58483/BTP2, a novel store-operated Ca2+ entry blocker, on T cell-mediated immune responses in vivo. Int Immunopharmacol. 2008 Dec 20;8(13-14):1787-9
Title: Ohga K, et al. The suppressive effects of YM-58483/BTP-2, a store-operated Ca2+ entry blocker, on inflammatory mediator release in vitro and airway responses in vivo. Pulm Pharmacol Ther. 2008;21(2):360-9
Title: Yoshino T, et al. YM-58483, a selective CRAC channel inhibitor, prevents antigen-induced airway eosinophilia and late phase asthmatic responses via Th2 cytokine inhibition in animal models. Eur J Pharmacol. 2007 Apr 10;560(2-3):225-33
