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Title: Translocator protein as a promising target for novel anxiolytics.
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Title: Synthesis and structure-activity relationship studies in translocator protein ligands based on a pyrazolo[3,4-b]quinoline scaffold.
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Title: Synthesis and evaluation of novel carbon-11 labeled oxopurine analogues for positron emission tomography imaging of translocator protein (18 kDa) in peripheral organs.
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Title: In vivo positron emission tomographic imaging of glial responses to amyloid-beta and tau pathologies in mouse models of Alzheimer's disease and related disorders.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20110323
Title: Variation in binding affinity of the novel anxiolytic XBD173 for the 18 kDa translocator protein in human brain.
Journal: Synapse (New York, N.Y.)20110301
Title: Imaging of peripheral-type benzodiazepine receptor in tumor: carbon ion irradiation reduced the uptake of a positron emission tomography ligand [11C]DAC in tumor.
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Title: Ultrafast LC method for purification and metabolite analysis of PET probes.
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Title: Evaluation of N-benzyl-N-[11C]methyl-2- (7-methyl-8-oxo-2-phenyl-7,8-dihydro-9H-purin-9-yl)acetamide ([11C]DAC) as a novel translocator protein (18 kDa) radioligand in kainic acid-lesioned rat.
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Title: Lack of tolerance to anxiolysis and withdrawal symptoms in mice repeatedly treated with AC-5216, a selective TSPO ligand.
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Title: Translocator protein (18 kD) as target for anxiolytics without benzodiazepine-like side effects.
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Title: Quantitative analysis of peripheral benzodiazepine receptor in the human brain using PET with (11)C-AC-5216.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine20090701
Title: [18F]FEAC and [18F]FEDAC: Two novel positron emission tomography ligands for peripheral-type benzodiazepine receptor in the brain.
Journal: Bioorganic & medicinal chemistry letters20090315
Title: Involvement of neurosteroids in the anxiolytic-like effects of AC-5216 in mice.
Journal: Pharmacology, biochemistry, and behavior20080401
Title: In vitro and ex vivo autoradiography studies on peripheral-type benzodiazepine receptor binding using [11C]AC-5216 in normal and kainic acid-lesioned rats.
Journal: Neuroscience letters20071127
Title: 11C-AC-5216: a novel PET ligand for peripheral benzodiazepine receptors in the primate brain.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine20071101
Title: Blood flow dependence of the intratumoral distribution of peripheral benzodiazepine receptor binding in intact mouse fibrosarcoma.
Journal: Nuclear medicine and biology20061101
Title: Antianxiety and antidepressant-like effects of AC-5216, a novel mitochondrial benzodiazepine receptor ligand.
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