[1]Gomi,Shuichi;Nishizuka,Toshio;Ushiroda,Osamu;Uchida,Naoki;Takahashi,Hirotada;Sumi,Shinjiro[Heterocycles,1998,vol.48,#11,p.2231-2244]
[1]Gomi,Shuichi;Nishizuka,Toshio;Ushiroda,Osamu;Uchida,Naoki;Takahashi,Hirotada;Sumi,Shinjiro[Heterocycles,1998,vol.48,#11,p.2231-2244]
[1]Gomi,Shuichi;Nishizuka,Toshio;Ushiroda,Osamu;Uchida,Naoki;Takahashi,Hirotada;Sumi,Shinjiro[Heterocycles,1998,vol.48,#11,p.2231-2244]
[1]CurrentPatentAssignee:LIGHTSCIENCESONCOLOGYINC-WO2008/5308,2008,A2Locationinpatent:Page/Pagecolumn34
Title: Preclinical in vivo evaluation of NPe6-mediated photodynamic therapy on normal vasculature.
Journal: Lasers in surgery and medicine 20120201
Title: Tissue damage in the canine normal esophagus by photoactivation with talaporfin sodium (laserphyrin): a preclinical study.
Journal: PloS one 20120101
Title: Myocardial electrical conduction block induced by photosensitization reaction in exposed porcine hearts in vivo.
Journal: Lasers in surgery and medicine 20111201
Title: Inhibition of endocytic processes by photodynamic therapy.
Journal: Lasers in surgery and medicine 20110901
Title: Molecular determinants of photodynamic therapy for lung cancers.
Journal: Lasers in surgery and medicine 20110901
Title: New aspects of photodynamic therapy for central type early stage lung cancer.
Journal: Lasers in surgery and medicine 20110901
Title: Advantages of laserphyrin compared with photofrin in photodynamic therapy for bile duct carcinoma.
Journal: Journal of hepato-biliary-pancreatic sciences 20110701
Title: Cell death via mitochondrial apoptotic pathway due to activation of Bax by lysosomal photodamage.
Journal: Free radical biology & medicine 20110701
Title: Sonodynamic cancer therapy: a non-invasive and repeatable approach using low-intensity ultrasound with a sonosensitizer.
Journal: Anticancer research 20110701
Title: Effects of endosomal photodamage on membrane recycling and endocytosis.
Journal: Photochemistry and photobiology 20110501
Title: Determination of the tumor tissue optical properties during and after photodynamic therapy using inverse Monte Carlo method and double integrating sphere between 350 and 1000 nm.
Journal: Journal of biomedical optics 20110501
Title: Effects of photodynamic therapy on the endocytic pathway.
Journal: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20110430
Title: Characterization of cutaneous photosensitivity in healthy volunteers receiving talaporfin sodium.
Journal: Photodermatology, photoimmunology & photomedicine 20110401
Title: Sonodynamically-induced antitumor effect of mono-l-aspartyl chlorin e6 (NPe6).
Journal: Anticancer research 20110201
Title: Nonesterified cholesterol content of lysosomes modulates susceptibility to oxidant-induced permeabilization.
Journal: Free radical biology & medicine 20110115
Title: Photosensitization reaction-induced acute electrophysiological cell response of rat myocardial cells in short loading periods of talaporfin sodium or porfimer sodium.
Journal: Photochemistry and photobiology 20110101
Title: Evaluation of oxygen consumption of culture medium and in vitro photodynamic effect of talaporfin sodium in lung tumor cells.
Journal: Photomedicine and laser surgery 20100601
Title: Photodynamic therapy induces microRNA-210 and -296 expression in HeLa cells.
Journal: Journal of biophotonics 20100601
Title: Novel photodynamic therapy against biliary tract carcinoma using mono-L: -aspartyl chlorine e6: basic evaluation for its feasibility and efficacy.
Journal: Journal of hepato-biliary-pancreatic sciences 20100501
Title: Outcome of photodynamic therapy using NPe6 for bronchogenic carcinomas in central airways >1.0 cm in diameter.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20100401
Title: Breast cancer resistant protein (BCRP) is a molecular determinant of the outcome of photodynamic therapy (PDT) for centrally located early lung cancer.
Journal: Lung cancer (Amsterdam, Netherlands) 20100201
Title: The myocardial electrical blockade induced by photosensitization reaction.
Journal: IEEE transactions on bio-medical engineering 20100201
Title: Talaporfin-mediated photodynamic therapy for peritoneal metastasis of gastric cancer in an in vivo mouse model: drug distribution and efficacy studies.
Journal: International journal of oncology 20100201
Title: Management of multiple primary lung cancer in patients with centrally located early cancer lesions.
Journal: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20100101
Title: Talaporfin sodium.
Journal: Expert opinion on pharmacotherapy 20100101
Title: Histological responses of cutaneous vascular lesions following photodynamic therapy with talaporfin sodium: a chicken comb model.
Journal: The Keio journal of medicine 20090901
Title: Fluorescence diagnosis of lymph node metastasis of lung cancer in a mouse model.
Journal: Oncology reports 20090701
Title: [Clinical photodynamic diagnosis and therapy efficiency in oropharyngeal cancer].
Journal: Nihon Jibiinkoka Gakkai kaiho 20090501
Title: The optimization of fluorescence imaging of brain tumor tissue differentiated from brain edema--in vivo kinetic study of 5-aminolevulinic acid and talaporfin sodium.
Journal: Photodiagnosis and photodynamic therapy 20090301
Title: Amelioration of airway stenosis in rabbit models by photodynamic therapy with talaporfin sodium (NPe6).
Journal: Photochemistry and photobiology 20090101
Title: Therapeutic effects of a new photosensitizer for photodynamic therapy of early head and neck cancer in relation to tissue concentration.
Journal: Auris, nasus, larynx 20081201
Title: Time-dependent interactions of the two porphyrinic compounds chlorin e6 and mono-L-aspartyl-chlorin e6 with phospholipid vesicles probed by NMR spectroscopy.
Journal: Langmuir : the ACS journal of surfaces and colloids 20081104
Title: Differential effects of photodynamic therapy on morphologically distinct tumor cells derived from a single precursor cell.
Journal: Cancer letters 20080918
Title: Photodynamic therapy of C6-implanted glioma cells in the rat brain employing second-generation photosensitizer talaporfin sodium.
Journal: Photodiagnosis and photodynamic therapy 20080901
Title: Uptake and retention of the photosensitizer mono-L-asparthyl chlorine e6 in experimental malignant glioma.
Journal: Lasers in medical science 20080701
Title: Photodynamic therapy using talaporfin sodium for synovial membrane from rheumatoid arthritis patients and collagen-induced arthritis rats.
Journal: Clinical rheumatology 20080601
Title: In vivo confocal fluorescence imaging of the intratumor distribution of the photosensitizer mono-L-aspartylchlorin-e6.
Journal: Neoplasia (New York, N.Y.) 20080501
Title: High expression of GADD-45alpha and VEGF induced tumor recurrence via upregulation of IL-2 after photodynamic therapy using NPe6.
Journal: International journal of oncology 20080201
Title: Sonodynamically-induced apoptosis, necrosis, and active oxygen generation by mono-l-aspartyl chlorin e6.
Journal: Cancer science 20080101
Title: Bid is required in NPe6-PDT-induced apoptosis.
Journal: Photochemistry and photobiology 20080101
Title: Photosensitization reaction-induced electrical blockade in myocardial tissue.
Journal: Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference 20080101
Title: Photodynamic therapy for lung cancers based on novel photodynamic diagnosis using talaporfin sodium (NPe6) and autofluorescence bronchoscopy.
Journal: Lung cancer (Amsterdam, Netherlands) 20071201
Title: A Phase II safety and effect on time to tumor progression study of intratumoral light infusion technology using talaporfin sodium in patients with metastatic colorectal cancer.
Journal: Journal of surgical oncology 20071101
Title: Expression of vascular endothelial growth factor by photodynamic therapy with mono-L-aspartyl chlorin e6 (NPe6) in oral squamous cell carcinoma.
Journal: Oral oncology 20070701
Title: Survivin, a member of the inhibitor of apoptosis family, is induced by photodynamic therapy and is a target for improving treatment response.
Journal: Cancer research 20070515
Title: Index-of-refraction-dependent subcellular light scattering observed with organelle-specific dyes.
Journal: Journal of biomedical optics 20070101
Title: Intraocular biodistribution of mono-L-aspartyl chlorin e6 in a primate choroidal neovascularization model.
Journal: Ophthalmic surgery, lasers & imaging : the official journal of the International Society for Imaging in the Eye 20070101
Title: Mono-(L)-aspartylchlorin-e6.
Journal: Photochemistry and photobiology 20070101
Title: In vitro behavior of Porfimer sodium and Talaporfin sodium with high intensity pulsed irradiation.
Journal: Lasers in medical science 20061201
Title: Basic and clinical research on photodynamic therapy at Tokyo Medical University Hospital.
Journal: Lasers in surgery and medicine 20060601
Title: Photodynamic therapy with mono-L-aspartyl chlorin e6 can cause necrosis of squamous cell carcinoma of tongue: experimental study on an animal model of nude mouse.
Journal: Oral oncology 20060101
Title: Tumor viability using real-time spectral images.
Journal: Surgery today 20060101
Title: Sphingomyelins suppress the targeted disruption of lysosomes/endosomes by the photosensitizer NPe6 during photodynamic therapy.
Journal: The Biochemical journal 20051201
Title: Long-term inhibition of intimal hyperplasia using vascular photodynamic therapy in balloon-injured carotid arteries.
Journal: Medical molecular morphology 20051201
Title: Laser photocoagulation and, to a lesser extent, photodynamic therapy target and enhance adenovirus vector-mediated gene transfer in the rat retina.
Journal: Investigative ophthalmology & visual science 20051001
Title: Pharmacokinetics and clinical effects of mono-L-aspartyl chlorin e6 (NPe6) photodynamic therapy in adult patients with primary or secondary cancer of the skin and mucosal surfaces.
Journal: Photodermatology, photoimmunology & photomedicine 20050401
Title: Killing tumor cells: the effect of photodynamic therapy using mono-L-aspartyl chlorine and NS-398.
Journal: American journal of surgery 20050301
Title: Effects of photodynamic therapy using a fractionated dosing of mono-L-aspartyl chlorin e6 in a murine tumor.
Journal: Journal of photochemistry and photobiology. B, Biology 20050201
Title: Detection of photodynamic therapy-induced early apoptosis in human salivary gland tumor cells in vitro and in a mouse tumor model.
Journal: Oral oncology 20040901
Title: [Development of a novel photosensitizer, talaporfin sodium, for the photodynamic therapy (PDT)].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20040601
Title: Photodynamic therapy upregulates expression of Mac-1 and generation of leukotriene B(4) by human polymorphonuclear leukocytes.
Journal: Oral oncology 20040501
Title: Differential susceptibilities of murine hepatoma 1c1c7 and Tao cells to the lysosomal photosensitizer NPe6: influence of aryl hydrocarbon receptor on lysosomal fragility and protease contents.
Journal: Molecular pharmacology 20040401
Title: CHOP activation by photodynamic therapy increases treatment induced photosensitization.
Journal: Lasers in surgery and medicine 20040101
Title: Phase II clinical study of photodynamic therapy using mono-L-aspartyl chlorin e6 and diode laser for early superficial squamous cell carcinoma of the lung.
Journal: Lung cancer (Amsterdam, Netherlands) 20031001
Title: Pilot study of topical delivery of mono-L-aspartyl chlorin e6 (NPe6): implication of topical NPe6-photodynamic therapy.
Journal: Journal of pharmacological sciences 20031001
Title: In vitro photodynamic diagnosis of atherosclerotic wall changes with the use of mono-l-aspartyl chlorin e6. A preliminary report.
Journal: Kardiologia polska 20031001
Title: Talaporfin sodium. LS 11, ME 2906, mono-L-aspartyl chlorine e6, NP e6, NPE 6, taporfin sodium.
Journal: Drugs in R&D 20030101
Title: Photodynamic therapy of intestinal tumors with mono-L-aspartyl chlorin e6 (NPe6): a basic study.
Journal: Anticancer research 20030101
Title: Release of cytochrome c and activation of pro-caspase-9 following lysosomal photodamage involves Bid cleavage.
Journal: Cell death and differentiation 20020901
Title: Phase-resolved fluorescence study of mono-L-aspartyl chlorin E6.
Journal: Journal of photochemistry and photobiology. B, Biology 20020501
Title: Morphologic evaluation of the antitumor activity of photodynamic therapy (PDT) using mono-L-aspartyl chlorin e6 (NPe6) against uterine cervical carcinoma cell lines.
Journal: International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20020101
Title: New technology for deep light distribution in tissue for phototherapy.
Journal: Cancer journal (Sudbury, Mass.) 20020101
Title: Increased cytotoxic effects of photodynamic therapy in IL-6 gene transfected cells via enhanced apoptosis.
Journal: International journal of cancer 20010815
Title: Endovascular photodynamic therapy using mono-L-aspartyl-chlorin e6 to inhibit Intimal hyperplasia in balloon-injured rabbit arteries.
Journal: Lasers in surgery and medicine 20010101
Title: Toxicity of the photosensitizer NPe6 following intravitreal injection.
Journal: Ophthalmic surgery and lasers 20010101
Title: Retreatment effect of NPe6 photodynamic therapy on the normal primate macula.
Journal: Retina (Philadelphia, Pa.) 20010101
Title: Photodynamic therapy of experimental choroidal neovascularization with a hydrophilic photosensitizer: mono-L-aspartyl chlorin e6.
Journal: Retina (Philadelphia, Pa.) 20010101
Title: http://journals.lww.com/jto/Fulltext/2006/06000/Photodynamic_Therapy__PDT__for_Lung_Cancers.18.aspx
Title: http://meeting.ascopubs.org/cgi/content/abstract/24/18_suppl/7229