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219766-25-3,MFCD00117444
Catalog No.:AA00BF2R

219766-25-3 | ANA-12

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98%
in stock  
$11.00   $8.00
- +
5mg
98%
in stock  
$33.00   $23.00
- +
10mg
98%
in stock  
$48.00   $34.00
- +
50mg
98%
in stock  
$138.00   $96.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00BF2R
Chemical Name:
ANA-12
CAS Number:
219766-25-3
Molecular Formula:
C22H21N3O3S
Molecular Weight:
407.4854
MDL Number:
MFCD00117444
SMILES:
O=C1NCCCCC1NC(=O)c1ccccc1NC(=O)c1cc2c(s1)cccc2
Properties
Computed Properties
 
Complexity:
628  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
29  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
4  
Undefined Atom Stereocenter Count:
1  
XLogP3:
4.2  

Literature

Title: Cazorla M, et al. Identification of a low-molecular weight TrkB antagonist with anxiolytic and antidepressant activity in mice. J Clin Invest. 2011 May;121(5):1846-57.

Title: Fang X, et al. Brain-derived neurotrophic factor-TrkB signaling in the medial prefrontal cortex plays a role in the anhedonia-like phenotype after spared nerve injury. Eur Arch Psychiatry Clin Neurosci. 2018 Jun 7.

Title: Zhang JC, et al. Comparison of ketamine, 7,8-dihydroxyflavone, and ANA-12 antidepressant effects in the social defeat stress model of depression. Psychopharmacology (Berl). 2015 Dec;232(23):4325-35.

Title: Vassoler FM, et al. Epigenetic inheritance of a cocaine-resistance phenotype. Nat Neurosci. 2013 Jan;16(1):42-7.

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SDS
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Tags:219766-25-3 Molecular Formula|219766-25-3 MDL|219766-25-3 SMILES|219766-25-3 ANA-12