Home Other Building Blocks 300817-68-9
300817-68-9,MFCD03453544
Catalog No.:AA00BF4G

300817-68-9 | Bh3i-1

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥95%
in stock  
$63.00   $44.00
- +
5mg
≥97%
in stock  
$197.00   $138.00
- +
10mg
99%
in stock  
$303.00   $212.00
- +
25mg
≥97%
in stock  
$481.00   $337.00
- +
50mg
≥97%
in stock  
$781.00   $547.00
- +
100mg
≥97%
in stock  
$1,277.00   $894.00
- +
200mg
≥97%
in stock  
$2,254.00   $1,578.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00BF4G
Chemical Name:
Bh3i-1
CAS Number:
300817-68-9
Molecular Formula:
C15H14BrNO3S2
Molecular Weight:
400.3106
MDL Number:
MFCD03453544
SMILES:
CC(C(N1C(=S)S/C(=C/c2ccc(cc2)Br)/C1=O)C(=O)O)C
Properties
Properties
 
Form:
Solid  
Solubility:
DMSO: >10 mg/mL, soluble  
Storage:
Keep in dry area;2-8℃;  

Computed Properties
 
Complexity:
513  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
22  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
4  
Undefined Atom Stereocenter Count:
1  
Undefined Bond Stereocenter Count:
1  
XLogP3:
4.6  

Literature

Title: Wang L, et al. Development of dimeric modulators for anti-apoptotic Bcl-2 proteins. Bioorg Med Chem Lett. 2008 Jan 1;18(1):236-40.

Title: Degterev A, et al. Identification of small-molecule inhibitors of interaction between the BH3 domain and Bcl-xL. Nat Cell Biol. 2001 Feb;3(2):173-82.

Title: Porter JR, et al. Profiling small molecule inhibitors against helix-receptor interactions: the Bcl-2 family inhibitor BH3I-1 potently inhibits p53/hDM2. Chem Commun (Camb). 2010 Nov 14;46(42):8020-2.

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SDS
Tags:300817-68-9 Molecular Formula|300817-68-9 MDL|300817-68-9 SMILES|300817-68-9 Bh3i-1