Home Other Building Blocks 246529-22-6
246529-22-6,MFCD21608618
Catalog No.:AA00BGIP

246529-22-6 | Aramchol

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥95%
in stock  
$58.00   $40.00
- +
5mg
≥95%
in stock  
$142.00   $99.00
- +
10mg
≥95%
in stock  
$255.00   $178.00
- +
25mg
≥95%
in stock  
$492.00   $344.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00BGIP
Chemical Name:
Aramchol
CAS Number:
246529-22-6
Molecular Formula:
C44H79NO5
Molecular Weight:
702.1018
MDL Number:
MFCD21608618
SMILES:
CCCCCCCCCCCCCCCCCCCC(=O)N[C@H]1CC[C@]2([C@@H](C1)C[C@H]([C@@H]1[C@@H]2C[C@H](O)[C@]2([C@H]1CC[C@@H]2[C@@H](CCC(=O)O)C)C)O)C
Properties
Computed Properties
 
Complexity:
1020  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
11  
Heavy Atom Count:
50  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
23  
XLogP3:
13.1  

Literature

Title: Fatty acid bile acid conjugate inhibits hepatic stearoyl coenzyme A desaturase and is non-atherogenic.

Journal: Archives of medical research 20100801

Title: Treatment of preestablished diet-induced fatty liver by oral fatty acid-bile acid conjugates in rodents.

Journal: European journal of gastroenterology & hepatology 20081201

Title: Hypocholesterolemic effects of fatty acid bile acid conjugates (FABACs) in mice.

Journal: Archives of biochemistry and biophysics 20080301

Title: ABCA1-dependent but apoA-I-independent cholesterol efflux mediated by fatty acid-bile acid conjugates (FABACs).

Journal: The Biochemical journal 20060615

Title: New targets in and potential treatments for cholesterol gallstone disease.

Journal: Current opinion in investigational drugs (London, England : 2000) 20060401

Title: Faecal sterol output is increased by arachidyl amido cholanoic acid (Aramchol) in rats.

Journal: Biochemical Society transactions 20040201

Title: Prevention of diet-induced fatty liver in experimental animals by the oral administration of a fatty acid bile acid conjugate (FABAC).

Journal: Hepatology (Baltimore, Md.) 20030801

Title: Arachidyl amido cholanoic acid (Aramchol) is a cholesterol solubilizer and prevents the formation of cholesterol gallstones in inbred mice.

Journal: Lipids 20011001

Title: Safadi R, et al. The fatty acid-bile acid conjugate Aramchol reduces liver fat content in patients with nonalcoholic fatty liver disease. Clin Gastroenterol Hepatol. 2014 Dec;12(12):2085-91.e1.

Title: Iruarrizaga-Lejarreta M, et al. Role of Aramchol in steatohepatitis and fibrosis in mice. Hepatol Commun. 2017 Nov;1(9):911-927.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Tags:246529-22-6 Molecular Formula|246529-22-6 MDL|246529-22-6 SMILES|246529-22-6 Aramchol