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2002-60-0,MFCD00871830
Catalog No.:AA00BIF5

2002-60-0 | THIOURIC ACID

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250mg
2 weeks  
$1,980.00   $1,386.00
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1g
2 weeks  
$4,633.00   $3,243.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00BIF5
Chemical Name:
THIOURIC ACID
CAS Number:
2002-60-0
Molecular Formula:
C5H4N4O2S
Molecular Weight:
184.1759
MDL Number:
MFCD00871830
SMILES:
C12=C(NC(=O)N1)NC(=O)NC2=S
NSC Number:
46380
Properties
Computed Properties
 
Complexity:
334  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
12  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
4  
XLogP3:
-1.3  

Literature

Title: Thiopurine-induced toxicity is associated with dysfunction variant of the human molybdenum cofactor sulfurase gene (xanthinuria type II).

Journal: Toxicology and applied pharmacology 20180620

Title: Study of drug metabolism by xanthine oxidase.

Journal: International journal of molecular sciences 20120101

Title: Drug sensitivity patterns of HHV8 carrying body cavity lymphoma cell lines.

Journal: BMC cancer 20110101

Title: State-of-the-art: Immunosuppression and biologic therapy.

Journal: Digestive diseases (Basel, Switzerland) 20100101

Title: The development of an objective methodology to measure medication adherence to oral thiopurines in paediatric patients with acute lymphoblastic leukaemia--an exploratory study.

Journal: European journal of clinical pharmacology 20091101

Title: Influence of xanthine oxidase on thiopurine metabolism in Crohn's disease.

Journal: Alimentary pharmacology & therapeutics 20080915

Title: The role of xanthine oxidase in thiopurine metabolism: a case report.

Journal: Therapeutic drug monitoring 20071201

Title: In vitro study of 6-mercaptopurine oxidation catalysed by aldehyde oxidase and xanthine oxidase.

Journal: Drug metabolism and pharmacokinetics 20070801

Title: Application of HPLC to study the kinetics of a branched bi-enzyme system consisting of hypoxanthine-guanine phosphoribosyltransferase and xanthine oxidase--an important biochemical system to evaluate the efficiency of the anticancer drug 6-mercaptopurine in ALL cell line.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070501

Title: Nature and position of functional group on thiopurine substrates influence activity of xanthine oxidase--enzymatic reaction pathways of 6-mercaptopurine and 2-mercaptopurine are different.

Journal: Biochemistry. Biokhimiia 20070201

Title: Preferential inhibition of xanthine oxidase by 2-amino-6-hydroxy-8-mercaptopurine and 2-amino-6-purine thiol.

Journal: BMC biochemistry 20070101

Title: Cytotoxic drug sensitivity of Epstein-Barr virus transformed lymphoblastoid B-cells.

Journal: BMC cancer 20060101

Title: HPLC analysis of azathioprine metabolites in red blood cells, plasma and urine in renal transplant recipients.

Journal: International journal of clinical pharmacology and therapeutics 19951201

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