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Home Indole and Oxindoles 220509-74-0
220509-74-0,MFCD22581511
Catalog No.:AA00BIP2

220509-74-0 | Pyrrolidine,1-[(2,3-dihydro-2,3-dioxo-1H-indol-5-yl)sulfonyl]-2-(MethoxyMethyl)-,(2S)-

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
97%
in stock  
$350.00   $245.00
- +
5mg
97%
in stock  
$1,056.00   $739.00
- +
25mg
97%
in stock  
$3,091.00   $2,164.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00BIP2
Chemical Name:
Pyrrolidine,1-[(2,3-dihydro-2,3-dioxo-1H-indol-5-yl)sulfonyl]-2-(MethoxyMethyl)-,(2S)-
CAS Number:
220509-74-0
Molecular Formula:
C14H16N2O5S
Molecular Weight:
324.3522
MDL Number:
MFCD22581511
SMILES:
COC[C@@H]1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C(=O)N2
Properties
Computed Properties
 
Complexity:
570  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
22  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
4  
XLogP3:
0.3  

Literature

Title: Isatin 1,2,3-triazoles as potent inhibitors against caspase-3.

Journal: Bioorganic & medicinal chemistry letters 20110315

Title: Design, synthesis, and discovery of novel non-peptide inhibitor of Caspase-3 using ligand based and structure based virtual screening approach.

Journal: Bioorganic & medicinal chemistry 20090815

Title: Fluorinated isatin derivatives. Part 2. New N-substituted 5-pyrrolidinylsulfonyl isatins as potential tools for molecular imaging of caspases in apoptosis.

Journal: Journal of medicinal chemistry 20090611

Title: Fluorinated isatin derivatives. Part 1: synthesis of new N-substituted (S)-5-[1-(2-methoxymethylpyrrolidinyl)sulfonyl]isatins as potent caspase-3 and -7 inhibitors.

Journal: Bioorganic & medicinal chemistry 20090401

Title: 5-pyrrolidinylsulfonyl isatins as a potential tool for the molecular imaging of caspases in apoptosis.

Journal: Journal of medicinal chemistry 20061116

Title: Potent and selective nonpeptide inhibitors of caspases 3 and 7.

Journal: Journal of medicinal chemistry 20010607

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SDS
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Tags:220509-74-0 Molecular Formula|220509-74-0 MDL|220509-74-0 SMILES|220509-74-0 Pyrrolidine,1-[(2,3-dihydro-2,3-dioxo-1H-indol-5-yl)sulfonyl]-2-(MethoxyMethyl)-,(2S)-