Home Nitro Compounds 4008-48-4
4008-48-4,MFCD00006791
Catalog No.:AA00BXC4

4008-48-4 | 8-Hydroxy-5-nitroquinoline

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Purity
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100mg
98%
in stock  
$6.00   $4.00
- +
1g
98%
in stock  
$11.00   $8.00
- +
5g
98%
in stock  
$13.00   $9.00
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25g
95%
in stock  
$28.00   $20.00
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50g
95%
in stock  
$54.00   $38.00
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500g
97%
in stock  
$411.00   $288.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00BXC4
Chemical Name:
8-Hydroxy-5-nitroquinoline
CAS Number:
4008-48-4
Molecular Formula:
C9H6N2O3
Molecular Weight:
190.1555
MDL Number:
MFCD00006791
SMILES:
[O-][N+](=O)c1ccc(c2c1nccc2)O
Properties
Properties
 
BP:
419°C at 760 mmHg  
Form:
Solid  
MP:
181-183 °C(lit.)  
Refractive Index:
1.5570 (estimate)  
Solubility:
alcohol: very slightly soluble  
Storage:
Inert atmosphere;Room Temperature;  

Computed Properties
 
Complexity:
229  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
14  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
1  
XLogP3:
2.1  

Literature

Title: Experimental and theoretical quantum chemical investigations of 8-hydroxy-5-nitroquinoline.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20121001

Title: Synthesis and characterization of 8-hydroxyquinoline complexes of tin(IV) and their application in organic light emitting diode.

Journal: Journal of fluorescence 20120901

Title: Substituted oxines inhibit endothelial cell proliferation and angiogenesis.

Journal: Organic & biomolecular chemistry 20120421

Title: Cox-2 gene overexpression in ureteral stump urothelial carcinoma following nephrectomy for renal cell carcinoma: a case report.

Journal: Journal of medical case reports 20120101

Title: Nitroxoline (8-hydroxy-5-nitroquinoline) is more a potent anti-cancer agent than clioquinol (5-chloro-7-iodo-8-quinoline).

Journal: Cancer letters 20111215

Title: Novel mechanism of cathepsin B inhibition by antibiotic nitroxoline and related compounds.

Journal: ChemMedChem 20110801

Title: Electrochemistry of the antibacterial and antifungal drug nitroxoline and its determination in bulk form, pharmaceutical formulation and human blood.

Journal: Bioelectrochemistry (Amsterdam, Netherlands) 20110201

Title: Synergistic inhibition of endothelial cell proliferation, tube formation, and sprouting by cyclosporin A and itraconazole.

Journal: PloS one 20110101

Title: Redox-based inactivation of cysteine cathepsins by compounds containing the 4-aminophenol moiety.

Journal: PloS one 20110101

Title: Effect of nitroxoline on angiogenesis and growth of human bladder cancer.

Journal: Journal of the National Cancer Institute 20101215

Title: Thermodynamic investigations of nitroxoline sublimation by simultaneous DSC-FTIR method and isothermal TG analysis.

Journal: Journal of pharmaceutical sciences 20100101

Title: Evaluation of a Rapid Differentiation Test for Mycobacterium Tuberculosis from other Mycobacteria by Selective Inhibition with p-nitrobenzoic Acid using MGIT 960.

Journal: Journal of laboratory physicians 20100101

Title: [Species composition and antibiotic resistance of lactobacillus in infants].

Journal: Zhurnal mikrobiologii, epidemiologii, i immunobiologii 20100101

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Powder diffraction study of the hydrogen bonds in nitroxoline and its hydrochloride.

Journal: Acta crystallographica. Section C, Crystal structure communications 20020101

Title: [Is nitroxoline an allergen?].

Journal: Therapie 20020101

Title: In vitro activity of the chelating agents nitroxoline and oxine against Mycobacterium bovis BCG.

Journal: International journal of antimicrobial agents 20011201

Title: Abouelhassan Y, et al. Nitroxoline: a broad-spectrum biofilm-eradicating agent against pathogenic bacteria. Int J Antimicrob Agents. 2017 Feb;49(2):247-251.

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