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35065-29-3,MFCD00055551
Catalog No.:AA00BXYA

35065-29-3 | 2,2',3,4,4',5,5'-HEPTACHLOROBIPHENYL

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25mg
2 weeks  
$939.00   $658.00
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  • Properties
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00BXYA
Chemical Name:
2,2',3,4,4',5,5'-HEPTACHLOROBIPHENYL
CAS Number:
35065-29-3
Molecular Formula:
C12H3Cl7
Molecular Weight:
395.3232
MDL Number:
MFCD00055551
SMILES:
Clc1cc(Cl)c(cc1c1cc(Cl)c(c(c1Cl)Cl)Cl)Cl
Properties
Properties
 
Storage:
2-8℃;  

Computed Properties
 
Complexity:
313  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
19  
Rotatable Bond Count:
1  
XLogP3:
7.9  

Literature

Title: Lactational exposure of mice to low levels of non-dioxin-like polychlorinated biphenyls increases susceptibility to neuronal stress at a mature age.

Journal: Neurotoxicology 20160301

Title: Exposure to Endocrine-Disrupting Chemicals during Pregnancy and Weight at 7 Years of Age: A Multi-pollutant Approach.

Journal: Environmental health perspectives 20151001

Title: Effect-based assessment of persistent organic pollutant and pesticide dumpsite using mammalian CALUX reporter cell lines.

Journal: Environmental science and pollution research international 20151001

Title: Hydroxyl metabolite of PCB 180 induces DNA damage signaling and enhances the DNA damaging effect of benzo[a]pyrene.

Journal: Chemico-biological interactions 20150905

Title: Polychlorinated Biphenyls (PCB 101, 153, and 180) Impair Murine Macrophage Responsiveness to Lipopolysaccharide: Involvement of NF-κB Pathway.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20150901

Title: Grouping of histone deacetylase inhibitors and other toxicants disturbing neural crest migration by transcriptional profiling.

Journal: Neurotoxicology 20150901

Title: Non-dioxin-like polychlorinated biphenyls (PCB 101, PCB 153 and PCB 180) induce chondrocyte cell death through multiple pathways.

Journal: Toxicology letters 20150402

Title: Lactational exposure to low levels of the six indicator non-dioxin-like polychlorinated biphenyls induces DNA damage and repression of neuronal activity, in juvenile male mice.

Journal: Toxicology 20150203

Title: Polychlorinated biphenyls (PCB 101, PCB 153 and PCB 180) alter leptin signaling and lipid metabolism in differentiated 3T3-L1 adipocytes.

Journal: Toxicology and applied pharmacology 20140915

Title: Correlation of gene expression and contaminant concentrations in wild largescale suckers: a field-based study.

Journal: The Science of the total environment 20140615

Title: Dopamine-dependent behavior in adult rats after perinatal exposure to purity-controlled polychlorinated biphenyl congeners (PCB52 and PCB180).

Journal: Toxicology letters 20140103

Title: Role of the nuclear xenobiotic receptors CAR and PXR in induction of cytochromes P450 by non-dioxinlike polychlorinated biphenyls in cultured rat hepatocytes.

Journal: Toxicology and applied pharmacology 20131001

Title: Sexually dimorphic behavior after developmental exposure to characterize endocrine-mediated effects of different non-dioxin-like PCBs in rats.

Journal: Toxicology 20130906

Title: Perinatal exposure to purity-controlled polychlorinated biphenyl 52, 138, or 180 alters toxicogenomic profiles in peripheral blood of rats after 4 months.

Journal: Chemical research in toxicology 20130819

Title: Neurodevelopmental and behavioral toxicity via lactational exposure to the sum of six indicator non-dioxin-like-polychlorinated biphenyls (∑6 NDL-PCBs) in mice.

Journal: Toxicology 20120904

Title: Non-coplanar polychlorinated biphenyls (PCBs) are direct agonists for the human pregnane-X receptor and constitutive androstane receptor, and activate target gene expression in a tissue-specific manner.

Journal: Toxicology and applied pharmacology 20120815

Title: Biological monitoring of indoor-exposure to dioxin-like and non-dioxin-like polychlorinated biphenyls (PCB) in a public building.

Journal: Toxicology letters 20120813

Title: Long-term trends of continental-scale PCB patterns studied using a global atmosphere-ocean general circulation model.

Journal: Environmental science and pollution research international 20120701

Title: Association of serum levels of polychlorinated biphenyls with IL-8 mRNA expression in blood samples from asthmatic and non-asthmatic Japanese children.

Journal: Chemosphere 20120601

Title: Non-dioxin-like polychlorinated biphenyls interfere with neuronal differentiation of embryonic neural stem cells.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20111101

Title: Some OH-PCBs are more potent inhibitors of aromatase activity and (anti-) glucocorticoids than non-dioxin like (NDL)-PCBs and MeSO₂-PCBs.

Journal: Toxicology letters 20111010

Title: Transcriptomics identifies differences between ultrapure non-dioxin-like polychlorinated biphenyls (PCBs) and dioxin-like PCB126 in cultured peripheral blood mononuclear cells.

Journal: Toxicology 20110905

Title: In utero and lactational exposure to PCBs in mice: adult offspring show altered learning and memory depending on Cyp1a2 and Ahr genotypes.

Journal: Environmental health perspectives 20110901

Title: Auditory effects of developmental exposure to purity-controlled polychlorinated biphenyls (PCB52 and PCB180) in rats.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20110701

Title: Hepatic effects of a highly purified 2,2',3,4,4',5,5'-heptachlorbiphenyl (PCB 180) in male and female rats.

Journal: Toxicology 20110618

Title: In vitro toxicity profiling of ultrapure non-dioxin-like polychlorinated biphenyl congeners and their relative toxic contribution to PCB mixtures in humans.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20110501

Title: Effects of non-dioxin-like polychlorinated biphenyl congeners (PCB 101, PCB 153 and PCB 180) alone or mixed on J774A.1 macrophage cell line: modification of apoptotic pathway.

Journal: Toxicology letters 20110410

Title: Prenatal PCBs disrupt early neuroendocrine development of the rat hypothalamus.

Journal: Toxicology and applied pharmacology 20110401

Title: Endocrine disruption of brain sexual differentiation by developmental PCB exposure.

Journal: Endocrinology 20110201

Title: In utero and lactational exposure to a complex mixture of polychlorinated biphenyls: toxicity in pups dependent on the Cyp1a2 and Ahr genotypes.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20110101

Title: Differential long-term effects of developmental exposure to polychlorinated biphenyls 52, 138 or 180 on motor activity and neurotransmission. Gender dependence and mechanisms involved.

Journal: Neurochemistry international 20110101

Title: Postnatal exposure to PCB 153 and PCB 180, but not to PCB 52, produces changes in activity level and stimulus control in outbred male Wistar Kyoto rats.

Journal: Behavioral and brain functions : BBF 20110101

Title: Activation and potentiation of human GABAA receptors by non-dioxin-like PCBs depends on chlorination pattern.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20101101

Title: DDE in mothers' blood during pregnancy and lower respiratory tract infections in their infants.

Journal: Epidemiology (Cambridge, Mass.) 20100901

Title: POP accumulation in the food chain: Integrated risk model for sewage sludge application in agricultural soils.

Journal: Environment international 20100801

Title: Developmental exposure to polychlorinated biphenyls 52, 138 or 180 affects differentially learning or motor coordination in adult rats. Mechanisms involved.

Journal: Neuroscience 20100602

Title: Polychlorinated biphenyls PCB 52, PCB 180, and PCB 138 impair the glutamate-nitric oxide-cGMP pathway in cerebellar neurons in culture by different mechanisms.

Journal: Chemical research in toxicology 20100419

Title: Determination of organochlorine pesticide and polychlorinated biphenyl levels in adipose tissue of infertile men.

Journal: Environmental monitoring and assessment 20100301

Title: Evaluation of an hPXR reporter gene assay for the detection of aquatic emerging pollutants: screening of chemicals and application to water samples.

Journal: Analytical and bioanalytical chemistry 20100101

Title: Non-dioxin-like-PCBs phosphorylate Mdm2 at Ser166 and attenuate the p53 response in HepG2 cells.

Journal: Chemico-biological interactions 20091210

Title: Thyroid function and plasma concentrations of polyhalogenated compounds in Inuit adults.

Journal: Environmental health perspectives 20090901

Title: Chronic treatment with polychlorinated biphenyls (PCB) during pregnancy and lactation in the rat Part 2: Effects on reproductive parameters, on sex behavior, on memory retention and on hypothalamic expression of aromatase and 5alpha-reductases in the offspring.

Journal: Toxicology and applied pharmacology 20090815

Title: Transactivation potencies of Baikal seal constitutive active/androstane receptor by persistent organic pollutants and brominated flame retardants.

Journal: Environmental science & technology 20090815

Title: Chronic treatment with polychlorinated biphenyls (PCB) during pregnancy and lactation in the rat: Part 1: Effects on somatic growth, growth hormone-axis activity and bone mass in the offspring.

Journal: Toxicology and applied pharmacology 20090601

Title: A physiologically based pharmacokinetic model for the assessment of infant exposure to persistent organic pollutants in epidemiologic studies.

Journal: Environmental health perspectives 20090301

Title: Organochlorine exposure, immune gene variation, and risk of non-Hodgkin lymphoma.

Journal: Blood 20090226

Title: Association of organochlorine pesticides with peripheral neuropathy in patients with diabetes or impaired fasting glucose.

Journal: Diabetes 20081101

Title: Serum concentrations of indicator PCB congeners in the Czech adult population.

Journal: Chemosphere 20080701

Title: Polychlorinated biphenyl exposure and neuropsychological status among older residents of upper Hudson River communities.

Journal: Environmental health perspectives 20080201

Title: Dioxin-like compound load in bulk of Chlorofen--a technical chlorobiphenyl formulation from Poland.

Journal: Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering 20071101

Title: Food web-specific biomagnification of persistent organic pollutants.

Journal: Science (New York, N.Y.) 20070713

Title: Constitutive androstane receptor (CAR) as a potential sensing biomarker of persistent organic pollutants (POPs) in aquatic mammal: molecular characterization, expression level, and ligand profiling in Baikal seal (Pusa sibirica).

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20061101

Title: PCB exposure and in vivo CYP1A2 activity among Native Americans.

Journal: Environmental health perspectives 20050301

Title: Uptake and tissue-specific distribution of selected polychlorinated biphenyls in developing chicken embryos.

Journal: Environmental toxicology and chemistry 20050301

Title: Lineage-specific effects of polychlorinated biphenyls (PCB) on gene expression in the rabbit blastocyst.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20050101

Title: Retention indexes for temperature-programmed gas chromatography of polychlorinated biphenyls.

Journal: Analytical chemistry 20040915

Title: Assessment of xenoestrogenic exposure by a biomarker approach: application of the E-Screen bioassay to determine estrogenic response of serum extracts.

Journal: Environmental health : a global access science source 20030101

Title: Inhibition of E2-induced expression of BRCA1 by persistent organochlorines.

Journal: Breast cancer research : BCR 20020101

Title: Effect of highly bioaccumulated polychlorinated biphenyl congeners on estrogen and androgen receptor activity.

Journal: Toxicology 20010214

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Tags:35065-29-3 Molecular Formula|35065-29-3 MDL|35065-29-3 SMILES|35065-29-3 2,2',3,4,4',5,5'-HEPTACHLOROBIPHENYL |Organic_Building_Blocks