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3695-73-6,MFCD00065112
Catalog No.:AA00BY7Q

3695-73-6 | Glycyl-l-alanine

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1g
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5g
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$168.00   $118.00
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25g
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00BY7Q
Chemical Name:
Glycyl-l-alanine
CAS Number:
3695-73-6
Molecular Formula:
C5H10N2O3
Molecular Weight:
146.1445
MDL Number:
MFCD00065112
SMILES:
CC(C(=O)O)NC(=O)CN
Properties
Properties
 
BP:
417.4°C at 760 mmHg  
Form:
Solid  
MP:
>175°C (dec.)  
Storage:
Keep in dry area;-20 ℃;  

Computed Properties
 
Complexity:
146  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
10  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
3  
XLogP3:
-3.7  

Downstream Synthesis Route

[1]Wuensch,E.;Wendlberger,G.;Goehring,W.;Huebener,G.;Traving,B.[MonatsheftefurChemie,1993,vol.124,#5,p.577-586]

[2]Abderhalden;Neumann[Fermentforschung,1934,vol.14,p.133,140]

[1]Patton,W.etal.[AustralianJournalofChemistry,1969,vol.22,p.2709-2712]

[1]Kolbe,A.;Schuette,H.R.[JournalfurpraktischeChemie(Leipzig1954),1981,vol.323,#2,p.311-318]

90-59-5    3695-73-6   
2-(2-1-(3,5-Dibromo-2-hydroxy-phenyl)-meth-(Z)-ylidene-amino}-acetylamino)-propionicacid 

[1]Ikenishi;Kitagawa;Hirai[ChemicalandPharmaceuticalBulletin,1984,vol.32,#2,p.748-751]

[1]Wuensch,E.;Wendlberger,G.;Goehring,W.;Huebener,G.;Traving,B.[MonatsheftefurChemie,1993,vol.124,#5,p.577-586]

Literature

Title: Hydrolytic activity of vanadate toward serine-containing peptides studied by kinetic experiments and DFT theory.

Journal: Inorganic chemistry 20120820

Title: Polarizable molecular dynamics simulations of aqueous dipeptides.

Journal: The journal of physical chemistry. B 20120802

Title: Remodeling of the epitope repertoire of a candidate idiotype vaccine by targeting to lysosomal degradation in dendritic cells.

Journal: Cancer immunology, immunotherapy : CII 20120601

Title: Study of fragmentation pathways of metastable negative ions in aliphatic dipeptides using the statistical theory.

Journal: Rapid communications in mass spectrometry : RCM 20120415

Title: The Ubiquitin System and Kaposi's Sarcoma-Associated Herpesvirus.

Journal: Frontiers in microbiology 20120101

Title: Comparative analysis of Mycobacterium tuberculosis pe and ppe genes reveals high sequence variation and an apparent absence of selective constraints.

Journal: PloS one 20120101

Title: Hydrolysis of serine-containing peptides at neutral pH promoted by [MoO4]2- oxyanion.

Journal: Inorganic chemistry 20111205

Title: Fragmental modeling of hPepT2 and analysis of its binding features by docking studies and pharmacophore mapping.

Journal: Bioorganic & medicinal chemistry 20110801

Title: The role of the proteasome in the generation of MHC class I ligands and immune responses.

Journal: Cellular and molecular life sciences : CMLS 20110501

Title: Non-conventional sources of peptides presented by MHC class I.

Journal: Cellular and molecular life sciences : CMLS 20110501

Title: Dissociative electron attachment to glycyl-glycine, glycyl-alanine and alanyl-alanine.

Journal: Physical chemistry chemical physics : PCCP 20110314

Title: C-terminal UBA domains protect ubiquitin receptors by preventing initiation of protein degradation.

Journal: Nature communications 20110208

Title: Expression of Epstein-Barr Virus Gene and Clonality of Infiltrated T Lymphocytes in Epstein-Barr Virus-associated Gastric Carcinoma.

Journal: Immune network 20110201

Title: Very fast magic angle spinning (1)H-(14)N 2D solid-state NMR: sub-micro-liter sample data collection in a few minutes.

Journal: Journal of magnetic resonance (San Diego, Calif. : 1997) 20110101

Title: Antibodies elicited in response to EBNA-1 may cross-react with dsDNA.

Journal: PloS one 20110101

Title: Innate immune modulation in EBV infection.

Journal: Herpesviridae 20110101

Title: Evaluation of Epstein-Barr virus latent membrane protein 2 specific T-cell receptors driven by T-cell specific promoters using lentiviral vector.

Journal: Clinical & developmental immunology 20110101

Title: Functional dissection of the PE domain responsible for translocation of PE_PGRS33 across the mycobacterial cell wall.

Journal: PloS one 20110101

Title: HLA class II defects in Burkitt lymphoma: bryostatin-1-induced 17 kDa protein restores CD4+ T-cell recognition.

Journal: Clinical & developmental immunology 20110101

Title: Dual regulatory functions of the thin filament revealed by replacement of the troponin I inhibitory peptide with a linker.

Journal: The Journal of biological chemistry 20101203

Title: Epstein Barr virus-encoded EBNA1 interference with MHC class I antigen presentation reveals a close correlation between mRNA translation initiation and antigen presentation.

Journal: PLoS pathogens 20101001

Title: Transdermal delivery enhanced by antimicrobial peptides.

Journal: Journal of biomedical nanotechnology 20101001

Title: Chemistry. Opening the door to peptide-based porous solids.

Journal: Science (New York, N.Y.) 20100827

Title: An adaptable peptide-based porous material.

Journal: Science (New York, N.Y.) 20100827

Title: A comparative study of complex formation in the reactions of gold(III) with Gly-Gly, Gly-L-Ala and Gly-L-His dipeptides.

Journal: Bioorganic chemistry 20100801

Title: A potentially immunologically inert derivative of the reverse tetracycline-controlled transactivator.

Journal: Biotechnology letters 20100601

Title: Hsp90 inhibitors: a potential treatment for latent EBV infection?

Journal: Cell cycle (Georgetown, Tex.) 20100501

Title: Characterization of an human leucocyte antigen A2-restricted Epstein-Barr virus nuclear antigen-1-derived cytotoxic T-lymphocyte epitope.

Journal: Immunology 20100301

Title: Immune responses to Epstein-Barr virus: molecular interactions in the virus evasion of CD8+ T cell immunity.

Journal: Microbes and infection 20100301

Title: Epstein-Barr virus-encoded EBNA1 inhibits the canonical NF-kappaB pathway in carcinoma cells by inhibiting IKK phosphorylation.

Journal: Molecular cancer 20100101

Title: The synthesis of truncated polypeptides for immune surveillance and viral evasion.

Journal: PloS one 20100101

Title: The expression of genes coding for distinct types of glycine-rich proteins varies according to the biology of three metastriate ticks, Rhipicephalus (Boophilus) microplus, Rhipicephalus sanguineus and Amblyomma cajennense.

Journal: BMC genomics 20100101

Title: Candida albicans AGE3, the ortholog of the S. cerevisiae ARF-GAP-encoding gene GCS1, is required for hyphal growth and drug resistance.

Journal: PloS one 20100101

Title: Epstein-Barr virus-encoded EBNA1 enhances RNA polymerase III-dependent EBER expression through induction of EBER-associated cellular transcription factors.

Journal: Molecular cancer 20100101

Title: Burkitt lymphoma: pathogenesis and immune evasion.

Journal: Journal of oncology 20100101

Title: T cell detection of a B-cell tropic virus infection: newly-synthesised versus mature viral proteins as antigen sources for CD4 and CD8 epitope display.

Journal: PLoS pathogens 20091201

Title: Peptide conformer acidity analysis of protein flexibility monitored by hydrogen exchange.

Journal: Biochemistry 20091006

Title: EBNA1-mediated recruitment of a histone H2B deubiquitylating complex to the Epstein-Barr virus latent origin of DNA replication.

Journal: PLoS pathogens 20091001

Title: Solvation and hydrogen bonding in alanine- and glycine-containing dipeptides probed using solution- and solid-state NMR spectroscopy.

Journal: Journal of the American Chemical Society 20090715

Title: Peptide aggregation and solvent electrostriction in a simple zwitterionic dipeptide via molecular dynamics simulations.

Journal: The Journal of chemical physics 20090707

Title: Stimulation of Akt poly-ubiquitination and proteasomal degradation in P388D1 cells by 7-ketocholesterol and 25-hydroxycholesterol.

Journal: Archives of biochemistry and biophysics 20090701

Title: Backbone conformational dependence of peptide acidity.

Journal: Biophysical chemistry 20090401

Title: Transport and signaling via the amino acid binding site of the yeast Gap1 amino acid transceptor.

Journal: Nature chemical biology 20090101

Title: Identification and expression analysis of WRKY transcription factor genes in canola (Brassica napus L.) in response to fungal pathogens and hormone treatments.

Journal: BMC plant biology 20090101

Title: Commentary: mechanistic considerations for associations between formaldehyde exposure and nasopharyngeal carcinoma.

Journal: Environmental health : a global access science source 20090101

Title: Post-transplant lymphoproliferative disorders: role of viral infection, genetic lesions and antigen stimulation in the pathogenesis of the disease.

Journal: Mediterranean journal of hematology and infectious diseases 20090101

Title: Contribution of viral recombinants to the study of the immune response against the Epstein-Barr virus.

Journal: Seminars in cancer biology 20081201

Title: Structure of N,N'-bis(amino acids) in the solid state and in solution. A 13C and 15N CPMAS NMR study.

Journal: The Journal of organic chemistry 20081107

Title: Gly-Ala repeats induce position- and substrate-specific regulation of 26 S proteasome-dependent partial processing.

Journal: The Journal of biological chemistry 20081031

Title: Epstein-Barr nuclear antigen 1 contributes to nasopharyngeal carcinoma through disruption of PML nuclear bodies.

Journal: PLoS pathogens 20081001

Title: Retrieval of spectral and dynamic properties from two-dimensional infrared pump-probe experiments.

Journal: Journal of computational chemistry 20080715

Title: Charge-based interactions between peptides observed as the dominant force for association in aqueous solution.

Journal: Angewandte Chemie (International ed. in English) 20080101

Title: Urea-amide preferential interactions in water: quantitative comparison of model compound data with biopolymer results using water accessible surface areas.

Journal: The journal of physical chemistry. B 20070816

Title: A gammaherpesviral internal repeat contributes to latency amplification.

Journal: PloS one 20070101

Title: Epstein-Barr virus latency switch in human B-cells: a physico-chemical model.

Journal: BMC systems biology 20070101

Title: Role of the ubiquitin system and tumor viruses in AIDS-related cancer.

Journal: BMC biochemistry 20070101

Title: Human PEPT1 pharmacophore distinguishes between dipeptide transport and binding.

Journal: Journal of medicinal chemistry 20060615

Title: Characterization of an immuno 'stealth' derivative of the herpes simplex virus thymidine-kinase gene.

Journal: Cancer gene therapy 20060601

Title: [Chiral separation of dipeptides by capillary electrophoresis].

Journal: Se pu = Chinese journal of chromatography 20060301

Title: Peptide derivatization as a strategy to form fixed-charge peptide radicals.

Journal: Rapid communications in mass spectrometry : RCM 20060101

Title: Kinetics of the interaction of sulfate and hydrogen phosphate radicals with small peptides of glycine, alanine, tyrosine and tryptophan.

Journal: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20051001

Title: Transpeptidation reactions of a specific substrate catalyzed by the Streptomyces R61 DD-peptidase: the structural basis of acyl acceptor specificity.

Journal: Biochemistry 20050802

Title: Transpeptidation reactions of a specific substrate catalyzed by the streptomyces R61 DD-peptidase: characterization of a chromogenic substrate and acyl acceptor design.

Journal: Biochemistry 20050802

Title: Single peptide bonds exhibit poly(pro)II ('random coil') circular dichroism spectra.

Journal: Journal of the American Chemical Society 20050713

Title: Modulation of p53 activity by IkappaBalpha: evidence suggesting a common phylogeny between NF-kappaB and p53 transcription factors.

Journal: BMC immunology 20050101

Title: On the mechanisms of oligopeptide reactions in solution and clay dispersion.

Journal: Journal of peptide science : an official publication of the European Peptide Society 20041201

Title: Manipulating sorting signals to generate co-expression of somatostatin and eGFP in the regulated secretory pathway from a monocistronic construct.

Journal: Journal of molecular endocrinology 20041001

Title: Repeat sequence of Epstein-Barr virus-encoded nuclear antigen 1 protein interrupts proteasome substrate processing.

Journal: The Journal of biological chemistry 20040305

Title: Water molecule adsorption on protonated dipeptides.

Journal: Journal of the American Chemical Society 20040204

Title: Structural and NMR investigations of the ternary adducts of twenty alpha-amino acids and selected dipeptides with a chiral, diaqua-ytterbium complex.

Journal: Dalton transactions (Cambridge, England : 2003) 20040107

Title: Formation of iminium ions by fragmentation of a2 ions.

Journal: Rapid communications in mass spectrometry : RCM 20040101

Title: Inhibition of ubiquitin/proteasome-dependent proteolysis in Saccharomyces cerevisiae by a Gly-Ala repeat.

Journal: FEBS letters 20031204

Title: Creation of immune 'stealth' genes for gene therapy through fusion with the Gly-Ala repeat of EBNA-1.

Journal: Gene therapy 20031101

Title: Synthesis and hybridization property of novel 2',5'-isoDNA mimic chiral peptide nucleic acids.

Journal: Bioorganic & medicinal chemistry letters 20030324

Title: Characterisation of intestinal peptide transporter of the Antarctic haemoglobinless teleost Chionodraco hamatus.

Journal: The Journal of experimental biology 20030201

Title: Peroxo-bridged divanadate as selective bromide oxidant in bromoperoxidation.

Journal: Molecular and cellular biochemistry 20020701

Title: Detection of nonderivatized peptides in capillary electrophoresis using quenched phosphorescence.

Journal: Analytical chemistry 20011101

Title: Targeting of EBNA1 for rapid intracellular degradation overrides the inhibitory effects of the Gly-Ala repeat domain and restores CD8+ T cell recognition.

Journal: The Journal of biological chemistry 20010907

Title: Direct measurement indicates a slow cis/trans isomerization at the secondary amide peptide bond of glycylglycine.

Journal: Journal of the American Chemical Society 20010704

Title: cis-Inhibition of proteasomal degradation by viral repeats: impact of length and amino acid composition.

Journal: FEBS letters 20010615

Title: beta-Subunit 102-104 residues are crucial to confer FSH activity to equine LH/CG but are not sufficient to confer FSH activity to human CG.

Journal: The Journal of endocrinology 20010401

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Tags:3695-73-6 Molecular Formula|3695-73-6 MDL|3695-73-6 SMILES|3695-73-6 Glycyl-l-alanine