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Home Other Building Blocks 395104-30-0
395104-30-0,MFCD16038646
Catalog No.:AA00BYF3

395104-30-0 | Cc-401

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$152.00   $106.00
- +
5mg
≥98%
in stock  
$668.00   $467.00
- +
10mg
≥98%
in stock  
$1,180.00   $826.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00BYF3
Chemical Name:
Cc-401
CAS Number:
395104-30-0
Molecular Formula:
C22H24N6O
Molecular Weight:
388.4656
MDL Number:
MFCD16038646
SMILES:
C1CCN(CC1)CCOc1cccc(c1)c1n[nH]c2c1cc(cc2)c1[nH]ncn1
Properties
Computed Properties
 
Complexity:
516  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
29  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
6  
XLogP3:
3.8  

Downstream Synthesis Route
3040-44-6   
3-{1-perhydro-2H-pyran-2-yl-5-1-(triphenylmethyl)(1,2.4-triazol-3-yl)-1H-indazol-3-yl}phenol 
  395104-30-0 

[1]CurrentPatentAssignee:BRISTOL-MYERSSQUIBBCO-WO2006/102363,2006,A1Locationinpatent:Page/Pagecolumn35-36

Literature

Title: Aryl Hydrocarbon Receptor Ligand 5F 203 Induces Oxidative Stress That Triggers DNA Damage in Human Breast Cancer Cells.

Journal: Chemical research in toxicology 20150518

Title: c-Jun N-terminal kinase mediates hepatic injury after rat liver transplantation.

Journal: Transplantation 20040815

Title: Ma FY, et al. A pathogenic role for c-Jun amino-terminal kinase signaling in renal fibrosis and tubular cell apoptosis. J Am Soc Nephrol. 2007 Feb;18(2):472-84.

Title: Vasilevskaya IA, et al. Inhibition of JNK Sensitizes Hypoxic Colon Cancer Cells to DNA-Damaging Agents. Clin Cancer Res. 2015 Sep 15;21(18):4143-52.

Title: Ma FY, et al. Blockade of the c-Jun amino terminal kinase prevents crescent formation and halts established anti-GBM glomerulonephritis in the rat. Lab Invest. 2009 Apr;89(4):470-84.

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SDS
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