Home Amines 36376-47-3
36376-47-3,MFCD01721796
Catalog No.:AA00C097

36376-47-3 | 4-Methylhistamine DiHCl

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1mg
≥95%
in stock  
$46.00   $32.00
- +
5mg
≥95%
in stock  
$166.00   $116.00
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10mg
≥95%
in stock  
$285.00   $199.00
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250mg
95%
in stock  
$344.00   $241.00
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1g
95%
in stock  
$412.00   $288.00
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5g
95%
in stock  
$1,642.00   $1,149.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00C097
Chemical Name:
4-Methylhistamine DiHCl
CAS Number:
36376-47-3
Molecular Formula:
C6H11N3
Molecular Weight:
125.1716
MDL Number:
MFCD01721796
SMILES:
Cc1c(CCN)nc[nH]1
Properties
Properties
 
Form:
Solid  
MP:
236-239°C  
Storage:
Room Temperature;  

Computed Properties
 
Complexity:
84.4  
Covalently-Bonded Unit Count:
3  
Heavy Atom Count:
11  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
2  

Literature

Title: Involvement of the histamine H4 receptor in clozapine-induced hematopoietic toxicity: Vulnerability under granulocytic differentiation of HL-60 cells.

Journal: Toxicology and applied pharmacology 20160901

Title: Involvement of histamine receptors in SAPK/JNK phosphorylation.

Journal: International immunopharmacology 20120601

Title: Role of histamine and its receptor subtypes in stimulation of conjunctival goblet cell secretion.

Journal: Investigative ophthalmology & visual science 20120501

Title: Human memory Th17 cells express a functional histamine H4 receptor.

Journal: The American journal of pathology 20120101

Title: Histamine H(4) receptor activation on human slan-dendritic cells down-regulates their pro-inflammatory capacity.

Journal: Immunology 20110101

Title: Synthesis and structural and pharmacological properties of cyclopropane-based conformationally restricted analogs of 4-methylhistamine as histamine H3/H4 receptor ligands.

Journal: Bioorganic & medicinal chemistry 20100201

Title: Inhibition of basophil activation by histamine: a sensitive and reproducible model for the study of the biological activity of high dilutions.

Journal: Homeopathy : the journal of the Faculty of Homeopathy 20091001

Title: Pharmacological characterization of the new histamine H4 receptor agonist VUF 8430.

Journal: British journal of pharmacology 20090501

Title: The histamine H4 receptor is functionally expressed on T(H)2 cells.

Journal: The Journal of allergy and clinical immunology 20090301

Title: Confirmation of biological effects of high dilutions. Effects of submolecular concentrations of histamine and 1-, 3- and 4-methylhistamines on human basophil activation.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20080101

Title: Comparison of the effect of 4-methyl histamine on human and mouse basophil activation.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20080101

Title: Histamine downregulates monocyte CCL2 production through the histamine H4 receptor.

Journal: The Journal of allergy and clinical immunology 20070801

Title: Histamine 4 receptor activation induces recruitment of FoxP3+ T cells and inhibits allergic asthma in a murine model.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20070615

Title: Evaluation of histamine H1-, H2-, and H3-receptor ligands at the human histamine H4 receptor: identification of 4-methylhistamine as the first potent and selective H4 receptor agonist.

Journal: The Journal of pharmacology and experimental therapeutics 20050901

Title: Histamine downregulates CD14 expression via H2 receptors on human monocytes.

Journal: Clinical immunology (Orlando, Fla.) 20030901

Title: Effects of histamine and related compounds on the differentiation of HL-60-Eo cells into eosinophils.

Journal: Methods and findings in experimental and clinical pharmacology 20010901

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Tags:36376-47-3 Molecular Formula|36376-47-3 MDL|36376-47-3 SMILES|36376-47-3 4-Methylhistamine DiHCl