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4105-39-9,MFCD07368402
Catalog No.:AA00C0HC

4105-39-9 | 2-methylthioadenosine

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Purity
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Price(USD)
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1mg
2 weeks  
$242.00   $169.00
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2mg
2 weeks  
$340.00   $238.00
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5mg
2 weeks  
$563.00   $394.00
- +
10mg
2 weeks  
$875.00   $613.00
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25mg
2 weeks  
$1,411.00   $988.00
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  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00C0HC
Chemical Name:
2-methylthioadenosine
CAS Number:
4105-39-9
Molecular Formula:
C11H15N5O4S
Molecular Weight:
313.3329
MDL Number:
MFCD07368402
SMILES:
OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1nc(SC)nc2N
Properties
Computed Properties
 
Complexity:
381  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
4  
Heavy Atom Count:
21  
Hydrogen Bond Acceptor Count:
9  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
3  
XLogP3:
-0.2  

Literature

Title: Preventative oral methylthioadenosine is anti-inflammatory and reduces DSS-induced colitis in mice.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20120701

Title: The P2Y(12) antagonists, 2MeSAMP and cangrelor, inhibit platelet activation through P2Y(12)/G(i)-dependent mechanism.

Journal: PloS one 20120101

Title: Investigations into the origin of the molecular recognition of several adenosine deaminase inhibitors.

Journal: Journal of medicinal chemistry 20110113

Title: Oral methylthioadenosine administration attenuates fibrosis and chronic liver disease progression in Mdr2-/- mice.

Journal: PloS one 20100101

Title: Management of erectile function by penile purinergic p2 receptors in the diabetic rat.

Journal: The Journal of urology 20090501

Title: P2Y1 receptor signaling enhances neuroprotection by astrocytes against oxidative stress via IL-6 release in hippocampal cultures.

Journal: Glia 20090201

Title: Inhibition of human betaine-homocysteine methyltransferase expression by S-adenosylmethionine and methylthioadenosine.

Journal: The Biochemical journal 20070101

Title: Regulation of death and survival in astrocytes by ADP activating P2Y1 and P2Y12 receptors.

Journal: Biochemical pharmacology 20061016

Title: Methylthioadenosine and polyamine biosynthesis in a Saccharomyces cerevisiae meu1delta mutant.

Journal: Biochemical and biophysical research communications 20060428

Title: Characterization of purine receptors in mouse thoracic aorta.

Journal: Journal of cardiovascular pharmacology 20040801

Title: Bacterial variations on the methionine salvage pathway.

Journal: BMC microbiology 20040101

Title: Anticoagulants (thrombin inhibitors) and aspirin synergize with P2Y12 receptor antagonism in thrombosis.

Journal: Circulation 20031125

Title: Activation of the alpha(2A)-adrenoceptor mediates deceleration of the deaggregation component of the response to ADP or 5-HT in human platelets in vitro.

Journal: Platelets 20010901

Title: In situ kinetic characterization of methylthioadenosine transport by the adenosine transporter (P2) of the African Trypanosoma brucei brucei and Trypanosoma brucei rhodesiense.

Journal: Biochemical pharmacology 20010215

Title: Intracellular metabolism of beta-L-2',3'-dideoxyadenosine: relevance to its limited antiviral activity.

Journal: Antimicrobial agents and chemotherapy 20000401

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Tags:4105-39-9 Molecular Formula|4105-39-9 MDL|4105-39-9 SMILES|4105-39-9 2-methylthioadenosine