Title: Silver nanoparticle-induced phosphorylation of histone H3 at serine 10 is due to dynamic changes in actin filaments and the activation of Aurora kinases.
Journal: Toxicology letters 20170705
Title: Increased microtubule assembly rates influence chromosomal instability in colorectal cancer cells.
Journal: Nature cell biology 20140801
Title: Centmitor-1, a novel acridinyl-acetohydrazide, possesses similar molecular interaction field and antimitotic cellular phenotype as rigosertib, on 01910.Na.
Journal: Molecular cancer therapeutics 20140501
Title: Sensitivity of BRCA2 mutated human cell lines to Aurora kinase inhibition.
Journal: Investigational new drugs 20120401
Title: Aurora B confers cancer cell resistance to TRAIL-induced apoptosis via phosphorylation of survivin.
Journal: Carcinogenesis 20120301
Title: Inhibition of Aurora kinases enhances chemosensitivity to temozolomide and causes radiosensitization in glioblastoma cells.
Journal: Journal of cancer research and clinical oncology 20120301
Title: Evolution of resistance to Aurora kinase B inhibitors in leukaemia cells.
Journal: PloS one 20120101
Title: Geminin overexpression induces mammary tumors via suppressing cytokinesis.
Journal: Oncotarget 20111201
Title: Formation of stable attachments between kinetochores and microtubules depends on the B56-PP2A phosphatase.
Journal: Nature cell biology 20111001
Title: ZM447439, the Aurora kinase B inhibitor, suppresses the growth of cervical cancer SiHa cells and enhances the chemosensitivity to cisplatin.
Journal: The journal of obstetrics and gynaecology research 20110601
Title: Antiproliferative effect of Aurora kinase targeting in mesothelioma.
Journal: Lung cancer (Amsterdam, Netherlands) 20101201
Title: Phosphorylation of histone H3 serine 10 in early mouse embryos: active phosphorylation at late S phase and differential effects of ZM447439 on first two embryonic mitoses.
Journal: Cell cycle (Georgetown, Tex.) 20101201
Title: The Aurora kinase inhibitor ZM447439 accelerates first meiosis in mouse oocytes by overriding the spindle assembly checkpoint.
Journal: Reproduction (Cambridge, England) 20101001
Title: Aurora kinase inhibitor ZM447439 induces apoptosis via mitochondrial pathways.
Journal: Biochemical pharmacology 20100115
Title: ZM447439, a novel promising aurora kinase inhibitor, provokes antiproliferative and proapoptotic effects alone and in combination with bio- and chemotherapeutic agents in gastroenteropancreatic neuroendocrine tumor cell lines.
Journal: Neuroendocrinology 20100101
Title: Trivalent dimethylarsenic compound induces histone H3 phosphorylation and abnormal localization of Aurora B kinase in HepG2 cells.
Journal: Toxicology and applied pharmacology 20091215
Title: Aurora kinase B modulates chromosome alignment in mouse oocytes.
Journal: Molecular reproduction and development 20091101
Title: Aurora kinase B, epigenetic state of centromeric heterochromatin and chiasma resolution in oocytes.
Journal: Reproductive biomedicine online 20090901
Title: Determinants for the efficiency of anticancer drugs targeting either Aurora-A or Aurora-B kinases in human colon carcinoma cells.
Journal: Molecular cancer therapeutics 20090701
Title: Length of mitotic arrest induced by microtubule-stabilizing drugs determines cell death after mitotic exit.
Journal: Molecular cancer therapeutics 20090601
Title: Discovery and development of aurora kinase inhibitors as anticancer agents.
Journal: Journal of medicinal chemistry 20090514
Title: Short and long-term tumor cell responses to Aurora kinase inhibitors.
Journal: Experimental cell research 20090415
Title: Investigating the role of Aurora kinases in RAS signaling.
Journal: Journal of cellular biochemistry 20090101
Title: Regulation of the meiotic prophase I to metaphase I transition in mouse spermatocytes.
Journal: Chromosoma 20081001
Title: Cell cycle dependent degradation of MCAK: evidence against a role in anaphase chromosome movement.
Journal: Cell cycle (Georgetown, Tex.) 20081001
Title: Aurora kinase family: a new target for anticancer drug.
Journal: Recent patents on anti-cancer drug discovery 20080601
Title: Molecular basis of drug resistance in aurora kinases.
Journal: Chemistry & biology 20080601
Title: ZM 447439 inhibition of aurora kinase induces Hep2 cancer cell apoptosis in three-dimensional culture.
Journal: Cell cycle (Georgetown, Tex.) 20080515
Title: Effects of the aurora kinase inhibitors AZD1152-HQPA and ZM447439 on growth arrest and polyploidy in acute myeloid leukemia cell lines and primary blasts.
Journal: Haematologica 20080501
Title: Requirement of aurora-A kinase in astral microtubule polymerization and spindle microtubule flux.
Journal: Cell cycle (Georgetown, Tex.) 20080415
Title: A novel treatment strategy targeting Aurora kinases in acute myelogenous leukemia.
Journal: Molecular cancer therapeutics 20070601
Title: Inhibition of survivin and aurora B kinase sensitizes mesothelioma cells by enhancing mitotic arrests.
Journal: International journal of radiation oncology, biology, physics 20070401
Title: MAPK interacts with XGef and is required for CPEB activation during meiosis in Xenopus oocytes.
Journal: Journal of cell science 20070315
Title: Caffeine promotes apoptosis in mitotic spindle checkpoint-arrested cells.
Journal: The Journal of biological chemistry 20070309
Title: Analysis of mitotic phosphorylation of borealin.
Journal: BMC cell biology 20070101
Title: Inhibition of Aurora kinases perturbs chromosome alignment and spindle checkpoint signaling in rat spermatocytes.
Journal: Experimental cell research 20061101
Title: Frequent overexpression of aurora B kinase, a novel drug target, in non-small cell lung carcinoma patients.
Journal: Molecular cancer therapeutics 20061101
Title: Validating Aurora B as an anti-cancer drug target.
Journal: Journal of cell science 20060901
Title: Accurate prediction of the relative potencies of members of a series of kinase inhibitors using molecular docking and MM-GBSA scoring.
Journal: Journal of medicinal chemistry 20060810
Title: Histone post-translational modification: from discovery to the clinic.
Journal: IDrugs : the investigational drugs journal 20060601
Title: Neither Aurora B activity nor histone H3 phosphorylation is essential for chromosome condensation during meiotic maturation of porcine oocytes.
Journal: Biology of reproduction 20060501
Title: SAR and inhibitor complex structure determination of a novel class of potent and specific Aurora kinase inhibitors.
Journal: Bioorganic & medicinal chemistry letters 20060301
Title: Discovery of novel and potent thiazoloquinazolines as selective Aurora A and B kinase inhibitors.
Journal: Journal of medicinal chemistry 20060209
Title: Mitotic requirement for aurora A kinase is bypassed in the absence of aurora B kinase.
Journal: FEBS letters 20050620
Title: The Ipl1/Aurora kinase family: methods of inhibition and functional analysis in mammalian cells.
Journal: Methods in molecular biology (Clifton, N.J.) 20050101
Title: Dawn of Aurora kinase inhibitors as anticancer drugs.
Journal: Expert opinion on investigational drugs 20040901
Title: Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores.
Journal: The Journal of cell biology 20030428
Title: Ditchfield C, et al. Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores. J Cell Biol. 2003 Apr 28;161(2):267-80.
Title: Long ZJ, et al. ZM 447439 inhibition of aurora kinase induces Hep2 cancer cell apoptosis in three-dimensionalculture. Cell Cycle. 2008 May 15;7(10):1473-9.
