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34675-49-5,MFCD00151766
Catalog No.:AA00C5J0

34675-49-5 | 6H-Dibenzo[b,d]pyran-9-methanol,6a,7,8,10a-tetrahydro-1-hydroxy-6,6-dimethyl-3-pentyl-,(6aR,10aR)-rel-

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  • Properties
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00C5J0
Chemical Name:
6H-Dibenzo[b,d]pyran-9-methanol,6a,7,8,10a-tetrahydro-1-hydroxy-6,6-dimethyl-3-pentyl-,(6aR,10aR)-rel-
CAS Number:
34675-49-5
Molecular Formula:
C21H30O3
Molecular Weight:
330.4611
MDL Number:
MFCD00151766
SMILES:
CCCCCc1cc(O)c2c(c1)OC([C@H]1[C@H]2C=C(CO)CC1)(C)C
Properties
Computed Properties
 
Complexity:
456  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
2  
Heavy Atom Count:
24  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
5  
XLogP3:
5.7  

Literature

Title: On-site test for cannabinoids in oral fluid.

Journal: Clinical chemistry 20121001

Title: Collision victim travels for 'seven kilometres' on top of the car that hit him.

Journal: Journal of forensic and legal medicine 20121001

Title: Psychomotor performance, subjective and physiological effects and whole blood Δ⁹-tetrahydrocannabinol concentrations in heavy, chronic cannabis smokers following acute smoked cannabis.

Journal: Journal of analytical toxicology 20120701

Title: Correlations and agreement between delta-9-tetrahydrocannabinol (THC) in blood plasma and timeline follow-back (TLFB)-assisted self-reported use of cannabis of patients with cannabis use disorder and psychotic illness attending the CapOpus randomized clinical trial.

Journal: Addiction (Abingdon, England) 20120601

Title: Differential signalling in human cannabinoid CB1 receptors and their splice variants in autaptic hippocampal neurones.

Journal: British journal of pharmacology 20120401

Title: [Does a positive finding of tetrahydrocannabinol in the blood result from ingestion of Indian frankincense (Boswellia serrata)?].

Journal: Archiv fur Kriminologie 20120101

Title: Oral fluid and plasma cannabinoid ratios after around-the-clock controlled oral Δ(9)-tetrahydrocannabinol administration.

Journal: Clinical chemistry 20111101

Title: Identification of recent cannabis use: whole-blood and plasma free and glucuronidated cannabinoid pharmacokinetics following controlled smoked cannabis administration.

Journal: Clinical chemistry 20111001

Title: Antagonist-elicited cannabis withdrawal in humans.

Journal: Journal of clinical psychopharmacology 20111001

Title: Plasma cannabinoid pharmacokinetics following controlled oral delta9-tetrahydrocannabinol and oromucosal cannabis extract administration.

Journal: Clinical chemistry 20110101

Title: A structural insight into the molecular recognition of a (-)-Delta9-tetrahydrocannabinol and the development of a sensitive, one-step, homogeneous immunocomplex-based assay for its detection.

Journal: Journal of molecular biology 20100723

Title: Validation of a two-dimensional gas chromatography mass spectrometry method for the simultaneous quantification of cannabidiol, Delta(9)-tetrahydrocannabinol (THC), 11-hydroxy-THC, and 11-nor-9-carboxy-THC in plasma.

Journal: Analytical and bioanalytical chemistry 20100501

Title: Concentrations of delta9-tetrahydrocannabinol and 11-nor-9-carboxytetrahydrocannabinol in blood and urine after passive exposure to Cannabis smoke in a coffee shop.

Journal: Journal of analytical toxicology 20100501

Title: [Interpretation of blood analysis data found after passive exposure to cannabis].

Journal: Archiv fur Kriminologie 20100101

Title: Delta9-tetrahydrocannabinol (THC), 11-hydroxy-THC, and 11-nor-9-carboxy-THC plasma pharmacokinetics during and after continuous high-dose oral THC.

Journal: Clinical chemistry 20091201

Title: Extended urinary Delta9-tetrahydrocannabinol excretion in chronic cannabis users precludes use as a biomarker of new drug exposure.

Journal: Drug and alcohol dependence 20091101

Title: Implications of plasma Delta9-tetrahydrocannabinol, 11-hydroxy-THC, and 11-nor-9-carboxy-THC concentrations in chronic cannabis smokers.

Journal: Journal of analytical toxicology 20091001

Title: Delta 9-tetrahydrocannabinol induces dopamine release in the human striatum.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20090201

Title: Delta-9-tetrahydrocannabinol (THC) serum concentrations and pharmacological effects in males after smoking a combination of tobacco and cannabis containing up to 69 mg THC.

Journal: Psychopharmacology 20081201

Title: Simultaneous analysis of THC and its metabolites in blood using liquid chromatography-tandem mass spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20081115

Title: Tetrahydrocannabinol and two of its metabolites in whole blood using liquid chromatography-tandem mass spectrometry.

Journal: Journal of analytical toxicology 20081001

Title: TRPV2 is activated by cannabidiol and mediates CGRP release in cultured rat dorsal root ganglion neurons.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20080611

Title: Cannabinoid concentrations in spot serum samples 24-48 hours after discontinuation of cannabis smoking.

Journal: Journal of analytical toxicology 20080301

Title: Simultaneous GC-EI-MS determination of Delta9-tetrahydrocannabinol, 11-hydroxy-Delta9-tetrahydrocannabinol, and 11-nor-9-carboxy-Delta9-tetrahydrocannabinol in human urine following tandem enzyme-alkaline hydrolysis.

Journal: Journal of analytical toxicology 20071001

Title: Simultaneous quantification of Delta9-tetrahydrocannabinol, 11-hydroxy-Delta9-tetrahydrocannabinol, and 11-nor-Delta9-tetrahydrocannabinol-9-carboxylic acid in human plasma using two-dimensional gas chromatography, cryofocusing, and electron impact-mass spectrometry.

Journal: Journal of chromatography. A 20070907

Title: Delta(9)-tetrahydrocannabinol, 11-hydroxy-delta(9)-tetrahydrocannabinol and 11-nor-9-carboxy-delta(9)-tetrahydrocannabinol in human plasma after controlled oral administration of cannabinoids.

Journal: Therapeutic drug monitoring 20060801

Title: Simultaneous analysis of the Delta9-THC metabolites 11-nor-9-carboxy-Delta9-THC and 11-hydroxy-Delta9-THC in meconium by GC-MS.

Journal: Journal of analytical toxicology 20050901

Title: Distribution of 11-nor-9-carboxy-Delta9-tetrahydrocannabinol in traffic fatality cases.

Journal: Journal of analytical toxicology 20050101

Title: Papain: a novel urine adulterant.

Journal: Journal of analytical toxicology 20050101

Title: Assessment of driving capability through the use of clinical and psychomotor tests in relation to blood cannabinoids levels following oral administration of 20 mg dronabinol or of a cannabis decoction made with 20 or 60 mg Delta9-THC.

Journal: Journal of analytical toxicology 20050101

Title: Tetrahydrocannabinols in clinical and forensic toxicology.

Journal: Przeglad lekarski 20050101

Title: Simultaneous and sensitive analysis of THC, 11-OH-THC, THC-COOH, CBD, and CBN by GC-MS in plasma after oral application of small doses of THC and cannabis extract.

Journal: Journal of analytical toxicology 20050101

Title: Urinary excretion profiles of 11-nor-9-carboxy-delta9-tetrahydrocannabinol and 11-hydroxy-delta9-THC: cannabinoid metabolites to creatinine ratio study IV.

Journal: Forensic science international 20040716

Title: Simultaneous determination of Delta9-tetrahydrocannabinol, 11-hydroxy-Delta9-tetrahydrocannabinol and 11-nor-9-carboxy- Delta9-tetrahydrocannabinol in human plasma by high-performance liquid chromatography/tandem mass spectrometry.

Journal: Journal of mass spectrometry : JMS 20040501

Title: Validated method for the simultaneous determination of Delta 9-tetrahydrocannabinol (THC), 11-hydroxy-THC and 11-nor-9-carboxy-THC in human plasma using solid phase extraction and gas chromatography-mass spectrometry with positive chemical ionization.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20031205

Title: [Serum cannabinoid levels 24 to 48 hours after cannabis smoking].

Journal: Archiv fur Kriminologie 20030101

Title: Delta(9)-THC, 11-OH-Delta(9)-THC and Delta(9)-THCCOOH plasma or serum to whole blood concentrations distribution ratios in blood samples taken from living and dead people.

Journal: Forensic science international 20011201

Title: Sex differences in antinociceptive and motoric effects of cannabinoids.

Journal: European journal of pharmacology 20011026

Title: Temporal indication of marijuana use can be estimated from plasma and urine concentrations of delta9-tetrahydrocannabinol, 11-hydroxy-delta9-tetrahydrocannabinol, and 11-nor-delta9-tetrahydrocannabinol-9-carboxylic acid.

Journal: Journal of analytical toxicology 20011001

Title: Cannabinoid-induced hypotension and bradycardia in rats mediated by CB1-like cannabinoid receptors.

Journal: The Journal of pharmacology and experimental therapeutics 19970601

Title: Molecular characterization of a peripheral receptor for cannabinoids.

Journal: Nature 19930902

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Tags:34675-49-5 Molecular Formula|34675-49-5 MDL|34675-49-5 SMILES|34675-49-5 6H-Dibenzo[b,d]pyran-9-methanol,6a,7,8,10a-tetrahydro-1-hydroxy-6,6-dimethyl-3-pentyl-,(6aR,10aR)-rel-