Home Amines 401900-40-1
401900-40-1,MFCD09027386
Catalog No.:AA00C6BH

401900-40-1 | S-3-(4-acetylamino-phenoxy)-2-hydroxy-2-methyl-N-(4-nitro-3-trifluoromethyl-phenyl)-propionamide

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5mg
98%(HPLC)
in stock  
$43.00   $30.00
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25mg
98%(HPLC)
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$112.00   $78.00
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100mg
98%(HPLC)
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$332.00   $233.00
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  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00C6BH
Chemical Name:
S-3-(4-acetylamino-phenoxy)-2-hydroxy-2-methyl-N-(4-nitro-3-trifluoromethyl-phenyl)-propionamide
CAS Number:
401900-40-1
Molecular Formula:
C19H18F3N3O6
Molecular Weight:
441.3579
MDL Number:
MFCD09027386
SMILES:
CC(=O)Nc1ccc(cc1)OC[C@@](C(=O)Nc1ccc(c(c1)C(F)(F)F)[N+](=O)[O-])(O)C
Properties
Computed Properties
 
Complexity:
663  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
31  
Hydrogen Bond Acceptor Count:
9  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
6  
XLogP3:
2.2  

Literature

Title: Identification of potent Yes1 kinase inhibitors using a library screening approach.

Journal: Bioorganic & medicinal chemistry letters 20130801

Title: SARM-S4 and metabolites detection in sports drug testing: a case report.

Journal: Forensic science international 20111210

Title: Mass spectrometric characterization of urinary metabolites of the selective androgen receptor modulator andarine (S-4) for routine doping control purposes.

Journal: Rapid communications in mass spectrometry : RCM 20100815

Title: Effects of a novel selective androgen receptor modulator on dexamethasone-induced and hypogonadism-induced muscle atrophy.

Journal: Endocrinology 20100801

Title: [Bone and Men's Health. Bone selective androgen receptor modulators].

Journal: Clinical calcium 20100201

Title: Nonsteroidal selective androgen receptor modulators (SARMs): dissociating the anabolic and androgenic activities of the androgen receptor for therapeutic benefit.

Journal: Journal of medicinal chemistry 20090625

Title: Effect of B-ring substitution pattern on binding mode of propionamide selective androgen receptor modulators.

Journal: Bioorganic & medicinal chemistry letters 20081015

Title: Selective Androgen Receptor Modulator (SARM) treatment prevents bone loss and reduces body fat in ovariectomized rats.

Journal: Pharmaceutical research 20070201

Title: In vivo metabolism and final disposition of a novel nonsteroidal androgen in rats and dogs.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20061001

Title: Selective androgen receptor modulator treatment improves muscle strength and body composition and prevents bone loss in orchidectomized rats.

Journal: Endocrinology 20051101

Title: A ligand-based approach to identify quantitative structure-activity relationships for the androgen receptor.

Journal: Journal of medicinal chemistry 20040715

Title: Pharmacokinetics of S-3-(4-acetylamino-phenoxy)-2-hydroxy-2-methyl-N-(4-nitro- 3-trifluoromethyl-phenyl)-propionamide in rats, a non-steroidal selective androgen receptor modulator.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20040301

Title: Donghua Yin, et al. Pharmacodynamics of selective androgen receptor modulators. J Pharmacol Exp Ther. 2003 Mar;304(3):1334-40.

Title: Ioannis Simitsidellis, et al. Selective androgen receptor modulators (SARMs) have specific impacts on the mouse uterus. J Endocrinol. 2019 Sep;242(3):227-239.

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