Home Other Building Blocks 334949-59-6
334949-59-6,MFCD18157583
Catalog No.:AA00C6C8

334949-59-6 | Bix-02188

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98%
in stock  
$19.00   $14.00
- +
5mg
98%
in stock  
$47.00   $33.00
- +
10mg
98%
in stock  
$70.00   $49.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00C6C8
Chemical Name:
Bix-02188
CAS Number:
334949-59-6
Molecular Formula:
C25H24N4O2
Molecular Weight:
412.4837
MDL Number:
MFCD18157583
SMILES:
CN(Cc1cccc(c1)N/C(=C/1\C(=O)Nc2c1ccc(c2)C(=O)N)/c1ccccc1)C
Properties
Computed Properties
 
Complexity:
645  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
31  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
6  
XLogP3:
3.9  

Literature

Title: A new high resolution screening method for study of phenotype stress responses of Saccharomyces cerevisae mutants.

Journal: Journal of microbiological methods 20111201

Title: Identification of pharmacological inhibitors of the MEK5/ERK5 pathway.

Journal: Biochemical and biophysical research communications 20081205

Title: Li L, et al. Fluid shear stress inhibits TNF-mediated JNK activation via MEK5-BMK1 in endothelial cells. Biochem Biophys Res Commun. 2008 May 23;370(1):159-63.

Title: Badshah II, et al. Erk5 is a mediator to TGFβ1-induced loss of phenotype and function in human podocytes. Front Pharmacol. 2014 Apr 21;5:71.

Title: Tatake RJ, et al. Identification of pharmacological inhibitors of the MEK5/ERK5 pathway. Biochem Biophys Res Commun. 2008 Dec 5;377(1):120-5.

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SDS
Tags:334949-59-6 Molecular Formula|334949-59-6 MDL|334949-59-6 SMILES|334949-59-6 Bix-02188