4033-39-0,MFCD09265268
Catalog No.:AA00C6Y5

4033-39-0 | L-2,3-Diaminopropionic acid

Pack Size
Purity
Availability
Price(USD)
Quantity
  
250mg
96%
in stock  
$107.00   $75.00
- +
1g
96%
in stock  
$250.00   $175.00
- +
5g
96%
in stock  
$726.00 $508.00
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA00C6Y5
Chemical Name:
L-2,3-Diaminopropionic acid
CAS Number:
4033-39-0
Molecular Formula:
C3H8N2O2
Molecular Weight:
104.1078
MDL Number:
MFCD09265268
SMILES:
N[C@H](C(=O)O)CN
Properties
Properties
 
BP:
325.6°C at 760 mmHg  
Storage:
Keep in dry area;2-8℃;  

Computed Properties
 
Complexity:
73.3  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
7  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
3  
Isotope Atom Count:
0  
Rotatable Bond Count:
2  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
-4.3  

Literature

Title: Capreomycin--a polypeptide antitubercular antibiotic with unusual binding properties toward copper(II).

Journal: Journal of inorganic biochemistry 20120101

Title: Structure-activity relationship (SAR) of the α-amino acid residue of potent tetrahydroisoquinoline (THIQ)-derived LFA-1/ICAM-1 antagonists.

Journal: Bioorganic & medicinal chemistry letters 20110101

Title: Mutation of L-2,3-diaminopropionic acid synthase genes blocks staphyloferrin B synthesis in Staphylococcus aureus.

Journal: BMC microbiology 20110101

Title: Incorporation of 2,3-diaminopropionic acid into linear cationic amphipathic peptides produces pH-sensitive vectors.

Journal: Chembiochem : a European journal of chemical biology 20100614

Title: Evaluation of [99mTc-(CO)3-X-Y-Bombesin(7-14)NH2] conjugates for targeting gastrin-releasing peptide receptors overexpressed on breast carcinoma.

Journal: Anticancer research 20100101

Title: Molecular characterization of staphyloferrin B biosynthesis in Staphylococcus aureus.

Journal: Molecular microbiology 20091101

Title: Highly enantioselective synthesis of (S)-alpha-alkyl-alpha,beta-diaminopropionic acids via asymmetric phase-transfer catalytic alkylation of 2-phenyl-2-imidazoline-4-carboxylic acid tert-butyl esters.

Journal: Organic letters 20090820

Title: N-Terminal 2,3-diaminopropionic acid (Dap) peptides as efficient methylglyoxal scavengers to inhibit advanced glycation endproduct (AGE) formation.

Journal: Bioorganic & medicinal chemistry 20090315

Title: Photoinduced linkage isomerism of {RuNO}(6) complexes with bioligands and related chelators.

Journal: Dalton transactions (Cambridge, England : 2003) 20090214

Title: Small-molecule inhibitors of integrin alpha2beta1 that prevent pathological thrombus formation via an allosteric mechanism.

Journal: Proceedings of the National Academy of Sciences of the United States of America 20090120

Title: L-2,3-diaminopropionate: one of the building blocks for the biosynthesis of Zwittermicin A in Bacillus thuringiensis subsp. kurstaki strain YBT-1520.

Journal: FEBS letters 20080903

Title: A convenient route to enantiopure 3-aryl-2,3-diaminopropanoic acids by diastereoselective Mannich reaction of camphor-based tricyclic iminolactone with imines.

Journal: The Journal of organic chemistry 20080502

Title: Small molecule inhibitors of integrin alpha2beta1.

Journal: Journal of medicinal chemistry 20071101

Title: Asymmetric synthesis of beta2-amino acids: 2-substituted-3-aminopropanoic acids from N-acryloyl SuperQuat derivatives.

Journal: Organic & biomolecular chemistry 20070907

Title: Variable stability heterodimeric coiled-coils from manipulation of electrostatic interface residue chain length.

Journal: Journal of the American Chemical Society 20070822

Title: Chiroptical properties of diamino carboxylic acids.

Journal: Chirality 20070701

Title: Orientation preferences of backbone secondary amide functional groups in peptide nucleic acid complexes: quantum chemical calculations reveal an intrinsic preference of cationic D-amino acid-based chiral PNA analogues for the P-form.

Journal: Biophysical journal 20070201

Title: Novel parent structures for inhibitors of the murine GABA transporters mGAT3 and mGAT4.

Journal: European journal of pharmacology 20050905

Title: Soluble MHC-peptide complexes induce rapid death of CD8+ CTL.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20050601

Title: Biochemical properties of new synthetic carnosine analogues containing the residue of 2,3-diaminopropionic acid: the effect of N-acetylation.

Journal: Amino acids 20050201

Title: A conventional route for the synthesis of new oxazolidin-2-one derivatives with beta-aminoalanines.

Journal: Chemical & pharmaceutical bulletin 20041001

Title: Synthesis of 9-membered dilactams derived from 1,3-diaminopropionic and glutamic acids.

Journal: The journal of peptide research : official journal of the American Peptide Society 20040301

Title: An efficient synthesis of a probe for protein function: 2,3-diaminopropionic acid with orthogonal protecting groups.

Journal: Organic letters 20040122

Title: Radiochemical investigations of gastrin-releasing peptide receptor-specific [(99m)Tc(X)(CO)3-Dpr-Ser-Ser-Ser-Gln-Trp-Ala-Val-Gly-His-Leu-Met-(NH2)] in PC-3, tumor-bearing, rodent models: syntheses, radiolabeling, and in vitro/in vivo studies where Dpr = 2,3-diaminopropionic acid and X = H2O or P(CH2OH)3.

Journal: Cancer research 20030715

Title: Gene cloning, purification, and characterization of 2,3-diaminopropionate ammonia-lyase from Escherichia coli.

Journal: Bioscience, biotechnology, and biochemistry 20021201

Title: Characterization of the surfactin synthetase C-terminal thioesterase domain as a cyclic depsipeptide synthase.

Journal: Biochemistry 20021112

Title: Novel spermine-amino acid conjugates and basic tripeptides enhance cleavage of the hairpin ribozyme at low magnesium ion concentration.

Journal: Bioorganic & medicinal chemistry letters 20011203

Title: Does the activation of poly (ADP-ribose) synthetase mediate tissue injury in the sepsis induced by cecal ligation and puncture?

Journal: Shock (Augusta, Ga.) 20010801

Title: Beta D305A mutant of tryptophan synthase shows strongly perturbed allosteric regulation and substrate specificity.

Journal: Biochemistry 20010626

Title: Glucosamine-6-phosphate synthase from Escherichia coli: determination of the mechanism of inactivation by N3-fumaroyl-L-2,3-diaminopropionic derivatives.

Journal: Biochemistry 19900417

Title: Cheema PS, et al. The neurotoxicity of beta-N-oxalyl-L-alphabeta-diaminopropionic acid, the neurotoxin from the pulse Lathyrus sativus. Biochem J. 1969 Mar;112(1):29-33.

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SDS
Tags:4033-39-0 Molecular Formula|4033-39-0 MDL|4033-39-0 SMILES|4033-39-0 L-2,3-Diaminopropionic acid
Catalog No.: AA00C6Y5
4033-39-0,MFCD09265268
4033-39-0 | L-2,3-Diaminopropionic acid
Pack Size: 250mg
Purity: 96%
in stock
$107.00 $75.00
Pack Size: 1g
Purity: 96%
in stock
$250.00 $175.00
Pack Size: 5g
Purity: 96%
in stock
$726.00 $508.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA00C6Y5
Chemical Name: L-2,3-Diaminopropionic acid
CAS Number: 4033-39-0
Molecular Formula: C3H8N2O2
Molecular Weight: 104.1078
MDL Number: MFCD09265268
SMILES: N[C@H](C(=O)O)CN
Properties
BP: 325.6°C at 760 mmHg  
Storage: Keep in dry area;2-8℃;  
Complexity: 73.3  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 1  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 7  
Hydrogen Bond Acceptor Count: 4  
Hydrogen Bond Donor Count: 3  
Isotope Atom Count: 0  
Rotatable Bond Count: 2  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: -4.3  
Literature fold

Title: Capreomycin--a polypeptide antitubercular antibiotic with unusual binding properties toward copper(II).

Journal: Journal of inorganic biochemistry20120101

Title: Structure-activity relationship (SAR) of the α-amino acid residue of potent tetrahydroisoquinoline (THIQ)-derived LFA-1/ICAM-1 antagonists.

Journal: Bioorganic & medicinal chemistry letters20110101

Title: Mutation of L-2,3-diaminopropionic acid synthase genes blocks staphyloferrin B synthesis in Staphylococcus aureus.

Journal: BMC microbiology20110101

Title: Incorporation of 2,3-diaminopropionic acid into linear cationic amphipathic peptides produces pH-sensitive vectors.

Journal: Chembiochem : a European journal of chemical biology20100614

Title: Evaluation of [99mTc-(CO)3-X-Y-Bombesin(7-14)NH2] conjugates for targeting gastrin-releasing peptide receptors overexpressed on breast carcinoma.

Journal: Anticancer research20100101

Title: Molecular characterization of staphyloferrin B biosynthesis in Staphylococcus aureus.

Journal: Molecular microbiology20091101

Title: Highly enantioselective synthesis of (S)-alpha-alkyl-alpha,beta-diaminopropionic acids via asymmetric phase-transfer catalytic alkylation of 2-phenyl-2-imidazoline-4-carboxylic acid tert-butyl esters.

Journal: Organic letters20090820

Title: N-Terminal 2,3-diaminopropionic acid (Dap) peptides as efficient methylglyoxal scavengers to inhibit advanced glycation endproduct (AGE) formation.

Journal: Bioorganic & medicinal chemistry20090315

Title: Photoinduced linkage isomerism of {RuNO}(6) complexes with bioligands and related chelators.

Journal: Dalton transactions (Cambridge, England : 2003)20090214

Title: Small-molecule inhibitors of integrin alpha2beta1 that prevent pathological thrombus formation via an allosteric mechanism.

Journal: Proceedings of the National Academy of Sciences of the United States of America20090120

Title: L-2,3-diaminopropionate: one of the building blocks for the biosynthesis of Zwittermicin A in Bacillus thuringiensis subsp. kurstaki strain YBT-1520.

Journal: FEBS letters20080903

Title: A convenient route to enantiopure 3-aryl-2,3-diaminopropanoic acids by diastereoselective Mannich reaction of camphor-based tricyclic iminolactone with imines.

Journal: The Journal of organic chemistry20080502

Title: Small molecule inhibitors of integrin alpha2beta1.

Journal: Journal of medicinal chemistry20071101

Title: Asymmetric synthesis of beta2-amino acids: 2-substituted-3-aminopropanoic acids from N-acryloyl SuperQuat derivatives.

Journal: Organic & biomolecular chemistry20070907

Title: Variable stability heterodimeric coiled-coils from manipulation of electrostatic interface residue chain length.

Journal: Journal of the American Chemical Society20070822

Title: Chiroptical properties of diamino carboxylic acids.

Journal: Chirality20070701

Title: Orientation preferences of backbone secondary amide functional groups in peptide nucleic acid complexes: quantum chemical calculations reveal an intrinsic preference of cationic D-amino acid-based chiral PNA analogues for the P-form.

Journal: Biophysical journal20070201

Title: Novel parent structures for inhibitors of the murine GABA transporters mGAT3 and mGAT4.

Journal: European journal of pharmacology20050905

Title: Soluble MHC-peptide complexes induce rapid death of CD8+ CTL.

Journal: Journal of immunology (Baltimore, Md. : 1950)20050601

Title: Biochemical properties of new synthetic carnosine analogues containing the residue of 2,3-diaminopropionic acid: the effect of N-acetylation.

Journal: Amino acids20050201

Title: A conventional route for the synthesis of new oxazolidin-2-one derivatives with beta-aminoalanines.

Journal: Chemical & pharmaceutical bulletin20041001

Title: Synthesis of 9-membered dilactams derived from 1,3-diaminopropionic and glutamic acids.

Journal: The journal of peptide research : official journal of the American Peptide Society20040301

Title: An efficient synthesis of a probe for protein function: 2,3-diaminopropionic acid with orthogonal protecting groups.

Journal: Organic letters20040122

Title: Radiochemical investigations of gastrin-releasing peptide receptor-specific [(99m)Tc(X)(CO)3-Dpr-Ser-Ser-Ser-Gln-Trp-Ala-Val-Gly-His-Leu-Met-(NH2)] in PC-3, tumor-bearing, rodent models: syntheses, radiolabeling, and in vitro/in vivo studies where Dpr = 2,3-diaminopropionic acid and X = H2O or P(CH2OH)3.

Journal: Cancer research20030715

Title: Gene cloning, purification, and characterization of 2,3-diaminopropionate ammonia-lyase from Escherichia coli.

Journal: Bioscience, biotechnology, and biochemistry20021201

Title: Characterization of the surfactin synthetase C-terminal thioesterase domain as a cyclic depsipeptide synthase.

Journal: Biochemistry20021112

Title: Novel spermine-amino acid conjugates and basic tripeptides enhance cleavage of the hairpin ribozyme at low magnesium ion concentration.

Journal: Bioorganic & medicinal chemistry letters20011203

Title: Does the activation of poly (ADP-ribose) synthetase mediate tissue injury in the sepsis induced by cecal ligation and puncture?

Journal: Shock (Augusta, Ga.)20010801

Title: Beta D305A mutant of tryptophan synthase shows strongly perturbed allosteric regulation and substrate specificity.

Journal: Biochemistry20010626

Title: Glucosamine-6-phosphate synthase from Escherichia coli: determination of the mechanism of inactivation by N3-fumaroyl-L-2,3-diaminopropionic derivatives.

Journal: Biochemistry19900417

Title: Cheema PS, et al. The neurotoxicity of beta-N-oxalyl-L-alphabeta-diaminopropionic acid, the neurotoxin from the pulse Lathyrus sativus. Biochem J. 1969 Mar;112(1):29-33.

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