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35873-49-5,MFCD00055116
Catalog No.:AA00C8XO

35873-49-5 | 8-CYCLOPENTYL-1,3-DIMETHYLXANTHINE

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Purity
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50mg
≥98%
in stock  
$132.00   $92.00
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100mg
≥98%
in stock  
$233.00   $163.00
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250mg
≥98%
in stock  
$549.00   $384.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00C8XO
Chemical Name:
8-CYCLOPENTYL-1,3-DIMETHYLXANTHINE
CAS Number:
35873-49-5
Molecular Formula:
C12H16N4O2
Molecular Weight:
248.2810
MDL Number:
MFCD00055116
SMILES:
Cn1c2nc([nH]c2c(=O)n(c1=O)C)C1CCCC1
NSC Number:
101806
Properties
Properties
 
Form:
Solid  
MP:
>250°C (dec.)  
Storage:
-20 ℃;  

Computed Properties
 
Complexity:
380  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
18  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
1  
XLogP3:
1.6  

Downstream Synthesis Route
35873-49-5    68220-26-8   
7-(2-chloro-6-fluorobenzyl)-8-cyclopentyl-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione 

[1]Patent:WO2004/9091,2004,A1.Locationinpatent:Page/Pagecolumn85

Literature

Title: Resveratrol improves hepatic steatosis by inducing autophagy through the cAMP signaling pathway.

Journal: Molecular nutrition & food research 20150801

Title: Adenosine receptor activation is responsible for prolonged depression of synaptic transmission after spreading depolarization in brain slices.

Journal: Neuroscience 20121025

Title: Evidence for constitutively-active adenosine receptors at mammalian motor nerve endings.

Journal: European journal of pharmacology 20120615

Title: Combined effects of THC and caffeine on working memory in rats.

Journal: British journal of pharmacology 20120401

Title: Wakefulness affects synaptic and network activity by increasing extracellular astrocyte-derived adenosine.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20120328

Title: Presynaptic inhibition of GABAergic synaptic transmission by adenosine in mouse hypothalamic hypocretin neurons.

Journal: Neuroscience 20120110

Title: Antihyperalgesic activity of nucleoside transport inhibitors in models of inflammatory pain in guinea pigs.

Journal: Journal of pain research 20120101

Title: Inducing hibernation in the arctic ground squirrel.

Journal: Lab animal 20110819

Title: Season primes the brain in an arctic hibernator to facilitate entrance into torpor mediated by adenosine A(1) receptors.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20110727

Title: Astrocyte-derived adenosine and A1 receptor activity contribute to sleep loss-induced deficits in hippocampal synaptic plasticity and memory in mice.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20110511

Title: Baclofen and adenosine inhibition of synaptic transmission at CA3-CA1 synapses display differential sensitivity to K+ channel blockade.

Journal: Cellular and molecular neurobiology 20110501

Title: Sleep fragmentation attenuates the hypercapnic (but not hypoxic) ventilatory responses via adenosine A1 receptors in awake rats.

Journal: Respiratory physiology & neurobiology 20110131

Title: Differential effects of selective adenosine antagonists on the effort-related impairments induced by dopamine D1 and D2 antagonism.

Journal: Neuroscience 20100929

Title: Epac stimulation induces rapid increases in connexin43 phosphorylation and function without preconditioning effect.

Journal: Pflugers Archiv : European journal of physiology 20100901

Title: Caffeine and a selective adenosine A2A receptor antagonist induce sensitization and cross-sensitization behavior associated with increased striatal dopamine in mice.

Journal: Journal of biomedical science 20100101

Title: Activation of adenosine low-affinity A3 receptors inhibits the enteric short interplexus neural circuit triggered by histamine.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20091201

Title: Differential effects of adenosine antagonists in two models of parkinsonian tremor.

Journal: Pharmacology, biochemistry, and behavior 20091101

Title: Epac1-induced cellular proliferation in prostate cancer cells is mediated by B-Raf/ERK and mTOR signaling cascades.

Journal: Journal of cellular biochemistry 20091101

Title: Epac2 induces synapse remodeling and depression and its disease-associated forms alter spines.

Journal: Nature neuroscience 20091001

Title: Activity-dependent release of adenosine inhibits the glutamatergic synaptic transmission and plasticity in the hypothalamic hypocretin/orexin neurons.

Journal: Neuroscience 20090915

Title: Release of adenosine and ATP during ischemia and epilepsy.

Journal: Current neuropharmacology 20090901

Title: The role of the basal forebrain adenosine receptors in sleep homeostasis.

Journal: Neuroreport 20090715

Title: Effects of chronic caffeine exposure on adenosinergic modulation of the discriminative-stimulus effects of nicotine, methamphetamine, and cocaine in rats.

Journal: Psychopharmacology 20090401

Title: Roles of purines in synaptic modulation evoked by hypercapnia in isolated spinal cord of neonatal rat in vitro.

Journal: British journal of pharmacology 20090401

Title: Feedback inhibition of action potential discharge by endogenous adenosine enhancement of the medium afterhyperpolarization.

Journal: The Journal of physiology 20090301

Title: The role of adenosine A(1) receptors in mediating the inhibitory effects of low frequency stimulation of perforant path on kindling acquisition in rats.

Journal: Neuroscience 20090218

Title: Modulation of gamma oscillations by endogenous adenosine through A1 and A2A receptors in the mouse hippocampus.

Journal: Neuropharmacology 20090201

Title: Astrocytic adenosine kinase regulates basal synaptic adenosine levels and seizure activity but not activity-dependent adenosine release in the hippocampus.

Journal: Neuropharmacology 20090201

Title: Ginsenosides attenuate kainic acid-induced synaptosomal oxidative stress via stimulation of adenosine A(2A) receptors in rat hippocampus.

Journal: Behavioural brain research 20090130

Title: PKA-dependent and independent cAMP signaling in 3T3-L1 fibroblasts differentiation.

Journal: Molecular and cellular endocrinology 20090127

Title: Intra-VTA adenosine A1 receptor activation blocks morphine stimulation of motor behavior and cortical and limbic Fos immunoreactivity.

Journal: European journal of pharmacology 20090114

Title: The effects of systemic, intrastriatal, and intrapallidal injections of caffeine and systemic injections of A2A and A1 antagonists on forepaw stepping in the unilateral 6-OHDA-lesioned rat.

Journal: Psychopharmacology 20090101

Title: Nitric oxide modulates the discharge rate of basal forebrain neurons.

Journal: Psychopharmacology 20081101

Title: Correlation of intrinsic optical signal, cerebral blood flow, and evoked potentials during activation of rat somatosensory cortex.

Journal: Journal of neurosurgery 20081001

Title: Microdialysis elevation of adenosine in the basal forebrain produces vigilance impairments in the rat psychomotor vigilance task.

Journal: Sleep 20081001

Title: Adenosine A1 receptor activation mediates NMDA receptor activity in a pertussis toxin-sensitive manner during normoxia but not anoxia in turtle cortical neurons.

Journal: Brain research 20080605

Title: Modest maternal caffeine exposure affects developing embryonic cardiovascular function and growth.

Journal: American journal of physiology. Heart and circulatory physiology 20080501

Title: The role of piriform cortex adenosine A1 receptors on hippocampal kindling.

Journal: The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 20080501

Title: Caffeine and accumbens shell dopamine.

Journal: Journal of neurochemistry 20071001

Title: Indomethacin stimulates activity and expression of ecto-5'-nucleotidase/CD73 in glioma cell lines.

Journal: European journal of pharmacology 20070813

Title: The role of adenosine A1 and A2A receptors of entorhinal cortex on piriform cortex kindled seizures in rats.

Journal: Pharmacological research 20070801

Title: Changes in neuromodulatory effect of adenosine A1 receptors on piriform cortex field potentials in amygdala kindled rats.

Journal: European journal of pharmacology 20070622

Title: Paired-pulse ratio of synaptically induced transporter currents at hippocampal CA1 synapses is not related to release probability.

Journal: Brain research 20070618

Title: Auto-inhibition of rat parallel fibre-Purkinje cell synapses by activity-dependent adenosine release.

Journal: The Journal of physiology 20070601

Title: Anticonvulsant effect of A1 but not A2A adenosine receptors of piriform cortex in amygdala-kindled rats.

Journal: Canadian journal of physiology and pharmacology 20070601

Title: Differential glutamate-dependent and glutamate-independent adenosine A1 receptor-mediated modulation of dopamine release in different striatal compartments.

Journal: Journal of neurochemistry 20070401

Title: Stimulation of adenosine A1 and A2A receptors by AMP in the submucosal plexus of guinea pig small intestine.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20070201

Title: Mechanisms linking adenosine A1 receptors and extracellular signal-regulated kinase 1/2 activation in human trabecular meshwork cells.

Journal: The Journal of pharmacology and experimental therapeutics 20070101

Title: A1 adenosine receptor-mediated modulation of neuronal ATP-sensitive K channels in rat substantia nigra.

Journal: Brain research 20061208

Title: Adenosine A1 receptor-mediated inhibition of in vitro prolactin secretion from the rat anterior pituitary.

Journal: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20061101

Title: Forskolin and 8-cyclopentyltheophylline synergistically facilitate the neuronal activity in the CA2 area of rat hippocampus via cAMP and non-cAMP cascades.

Journal: Sheng li xue bao : [Acta physiologica Sinica] 20061025

Title: Chronic activation of spinal adenosine A1 receptors results in hypersensitivity.

Journal: Neuroreport 20061023

Title: Contribution of adenosine receptors in the control of arteriolar tone and adenosine-angiotensin II interaction.

Journal: Kidney international 20060801

Title: A(1) adenosine receptor signal and AMPK involving caspase-9/-3 activation are responsible for adenosine-induced RCR-1 astrocytoma cell death.

Journal: Neurotoxicology 20060701

Title: Activity-dependent feedback modulation of spike patterning of supraoptic nucleus neurons by endogenous adenosine.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20060701

Title: Adenosine inhibits basal forebrain cholinergic and noncholinergic neurons in vitro.

Journal: Neuroscience 20060630

Title: GABAergic network activation of glial cells underlies hippocampal heterosynaptic depression.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20060517

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Neurogenic secretion mediated by the purinergic P2Y1 receptor in guinea-pig small intestine.

Journal: European journal of pharmacology 20060424

Title: Molecular mechanisms of adenosine-induced apoptosis in human HepG2 cells.

Journal: Acta pharmacologica Sinica 20060401

Title: Presynaptic effectors contributing to cAMP-induced synaptic potentiation in Drosophila.

Journal: Journal of neurobiology 20060215

Title: Purine P1 receptor-dependent immunostimulatory effects of antiviral acyclic analogues of adenine and 2,6-diaminopurine.

Journal: European journal of pharmacology 20060113

Title: Adenosine A1 and A2A receptors of hippocampal CA1 region have opposite effects on piriform cortex kindled seizures in rats.

Journal: Seizure 20060101

Title: Adenosine A1 receptors decrease thalamic excitation of inhibitory and excitatory neurons in the barrel cortex.

Journal: Neuroscience 20060101

Title: A detailed behavioral analysis of the acute motor effects of caffeine in the rat: involvement of adenosine A1 and A2A receptors.

Journal: Psychopharmacology 20051201

Title: Inhibitory control of the acute mu-withdrawal response by indirectly activated adenosine A1 and kappa-opioid systems in the Guinea-pig ileum; reversal by cholecystokinin.

Journal: Neurotoxicology 20051001

Title: Involvement of the cannabinoid CB1 receptor in the opioid inhibition of the response to cholecystokinin and acute withdrawal response.

Journal: Neurotoxicology 20051001

Title: Modulation of conventional outflow facility by the adenosine A1 agonist N6-cyclohexyladenosine.

Journal: Investigative ophthalmology & visual science 20051001

Title: Enhancement of wind-up by the combined administration of adenosine A1 receptor ligands on spinalized rats with carrageenan-induced inflammation.

Journal: Neuroscience letters 20050801

Title: Adenosine receptors co-operate with NMDA preconditioning to protect cerebellar granule cells against glutamate neurotoxicity.

Journal: Neuropharmacology 20050701

Title: Effects of emodin on synaptic transmission in rat hippocampal CA1 pyramidal neurons in vitro.

Journal: Neuropharmacology 20050701

Title: Effect of sleep deprivation on righting reflex in the rat is partially reversed by administration of adenosine A1 and A2 receptor antagonists.

Journal: Anesthesiology 20050601

Title: The role of adenosine A(1) receptors in the interaction between amygdala and entorhinal cortex of kindled rats.

Journal: Epilepsy research 20050601

Title: Phase-specific central regulatory systems of hibernation in Syrian hamsters.

Journal: Brain research 20050531

Title: Ginsenosides attenuate methamphetamine-induced behavioral side effects in mice via activation of adenosine A2A receptors: possible involvements of the striatal reduction in AP-1 DNA binding activity and proenkephalin gene expression.

Journal: Behavioural brain research 20050307

Title: A 'locked-on,' constitutively active mutant of the adenosine A1 receptor.

Journal: European journal of pharmacology 20050307

Title: Role of central and peripheral adenosine receptors in the cardiovascular responses to intraperitoneal injections of adenosine A1 and A2A subtype receptor agonists.

Journal: British journal of pharmacology 20050301

Title: Dynamics of fast synaptic excitation during trains of stimulation in myenteric neurons of guinea-pig ileum.

Journal: Autonomic neuroscience : basic & clinical 20050207

Title: Stabilizing effects of extracellular ATP on synaptic efficacy and plasticity in hippocampal pyramidal neurons.

Journal: The European journal of neuroscience 20050201

Title: Pharmacological preconditioning with resveratrol: role of CREB-dependent Bcl-2 signaling via adenosine A3 receptor activation.

Journal: American journal of physiology. Heart and circulatory physiology 20050101

Title: Does permanent carotid artery occlusion produce a 'preconditioning-like' effect towards more severe hypotension in energy metabolites? Role of cerebral adenosine.

Journal: Clinical and experimental pharmacology & physiology 20050101

Title: Deletion of presynaptic adenosine A1 receptors impairs the recovery of synaptic transmission after hypoxia.

Journal: Neuroscience 20050101

Title: Direct evidence for mutual interactions between perineuronal astrocytes and interneurons in the CA1 region of the rat hippocampus.

Journal: Neuroscience 20050101

Title: 2-Chloro-N6-cyclopentyladenosine enhances the anticonvulsant action of carbamazepine in the mouse maximal electroshock-induced seizure model.

Journal: Pharmacological reports : PR 20050101

Title: Stressor-related impairment of synaptic transmission in hippocampal slices from alpha-synuclein knockout mice.

Journal: The European journal of neuroscience 20041201

Title: Adenosine inhibits GABAergic and glycinergic transmission in adult rat substantia gelatinosa neurons.

Journal: Journal of neurophysiology 20041101

Title: Adenosine receptor-mediated modulation of dopamine release in the nucleus accumbens depends on glutamate neurotransmission and N-methyl-D-aspartate receptor stimulation.

Journal: Journal of neurochemistry 20041101

Title: Attenuation of cocaine-induced conditioned place preference by Polygala tenuifolia root extract.

Journal: Life sciences 20041022

Title: Spinal vs. supraspinal antinociceptive activity of the adenosine A(1) receptor agonist cyclopentyl-adenosine in rats with inflammation.

Journal: European journal of pharmacology 20040924

Title: Adenosine A(1)-receptor-mediated tonic inhibition of glutamate release at rat hippocampal CA3-CA1 synapses is primarily due to inhibition of N-type Ca(2+) channels.

Journal: European journal of pharmacology 20040924

Title: Allosteric modulation and constitutive activity of fusion proteins between the adenosine A1 receptor and different 351Cys-mutated Gi alpha-subunits.

Journal: European journal of pharmacology 20040919

Title: Deletion of the adenosine A1 receptor gene does not alter neuronal damage following ischaemia in vivo or in vitro.

Journal: The European journal of neuroscience 20040901

Title: Neuronal A1 receptors mediate increase in extracellular kynurenic acid after local intrastriatal adenosine infusion.

Journal: Journal of neurochemistry 20040801

Title: PAP 9704, a Korean herbal medicine attenuates methamphetamine-induced hyperlocomotion via adenosine A2A receptor stimulation in mice.

Journal: Biological & pharmaceutical bulletin 20040601

Title: Adenosine induces apoptosis in the human gastric cancer cells via an intrinsic pathway relevant to activation of AMP-activated protein kinase.

Journal: Biochemical pharmacology 20040515

Title: The role of intraspinal adenosine A1 receptors in sympathetic regulation.

Journal: European journal of pharmacology 20040510

Title: Endogenous adenosine modulates epileptiform activity in rat hippocampus in a receptor subtype-dependent manner.

Journal: The European journal of neuroscience 20040501

Title: Opposite modulatory roles for adenosine A1 and A2A receptors on glutamate and dopamine release in the shell of the nucleus accumbens. Effects of chronic caffeine exposure.

Journal: Journal of neurochemistry 20040301

Title: Cholecystokinin activates CCKB receptors to excite cells and depress EPSCs in the rat rostral nucleus accumbens in vitro.

Journal: The Journal of physiology 20040215

Title: Antioxidant propolis attenuates kainate-induced neurotoxicity via adenosine A1 receptor modulation in the rat.

Journal: Neuroscience letters 20040130

Title: Protection against kainate neurotoxicity by pyrrolidine dithiocarbamate.

Journal: Clinical and experimental pharmacology & physiology 20040101

Title: Glutamate-evoked release of adenosine and regulation of peripheral nociception.

Journal: Neuroscience 20040101

Title: Adenosine A(1) receptor-mediated presynaptic inhibition at the calyx of Held of immature rats.

Journal: The Journal of physiology 20031201

Title: Involvement of adenosine A1 and A2A receptors in the adenosinergic modulation of the discriminative-stimulus effects of cocaine and methamphetamine in rats.

Journal: The Journal of pharmacology and experimental therapeutics 20031201

Title: Sleep and its homeostatic regulation in mice lacking the adenosine A1 receptor.

Journal: Journal of sleep research 20031201

Title: Systemic hypoxia and the depression of synaptic transmission in rat hippocampus after carotid artery occlusion.

Journal: The Journal of physiology 20030801

Title: The effect of acute hypoxemia and hypotension on adenosine-mediated depression of evoked hippocampal synaptic transmission.

Journal: Experimental neurology 20030801

Title: Involvement of adenosine A1 and A2A receptors in the motor effects of caffeine after its acute and chronic administration.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20030701

Title: Dopamine and adenosine mediate substance P-induced depression of evoked IPSCs in the rat nucleus accumbens in vitro.

Journal: The European journal of neuroscience 20030701

Title: Impaired secretion of IL-10 by T cells from patients with common variable immunodeficiency--involvement of protein kinase A type I.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20030601

Title: Caffeine-mediated presynaptic long-term potentiation in hippocampal CA1 pyramidal neurons.

Journal: Journal of neurophysiology 20030601

Title: Low efficacy adenosine A1 agonists inhibit striatal acetylcholine release in rats improving central selectivity of action.

Journal: Neuroscience letters 20030529

Title: The influence of adenosine A3 receptor agonist: IB-MECA, on scopolamine- and MK-801-induced memory impairment.

Journal: Behavioural brain research 20030417

Title: Stimulatory effect of paeoniflorin on adenosine release to increase the glucose uptake into white adipocytes of Wistar rat.

Journal: Planta medica 20030401

Title: Neuroprotection by caffeine and adenosine A2A receptor blockade of beta-amyloid neurotoxicity.

Journal: British journal of pharmacology 20030401

Title: Substance P depresses excitatory synaptic transmission in the nucleus accumbens through dopaminergic and purinergic mechanisms.

Journal: Journal of neurophysiology 20030201

Title: The effect of oxygen and adenosine on lizard thermoregulation.

Journal: Physiological and biochemical zoology : PBZ 20030101

Title: Adenosinergic inhibition of basal forebrain wakefulness-active neurons: a simultaneous unit recording and microdialysis study in freely behaving cats.

Journal: Neuroscience 20030101

Title: Regulation by Rab3A of an endogenous modulator of neurotransmitter release at mouse motor nerve endings.

Journal: The Journal of physiology 20021201

Title: Effects of the adenosine A1 receptor allosteric modulators PD 81,723 and LUF 5484 on the striatal acetylcholine release.

Journal: European journal of pharmacology 20021115

Title: Saturation of neuroprotective effects of adenosine in cortical culture.

Journal: Neuroreport 20021115

Title: Comparison of the ability of adenosine kinase inhibitors and adenosine receptor agonists to attenuate thermal hyperalgesia and reduce motor performance in rats.

Journal: Pharmacology, biochemistry, and behavior 20021001

Title: Modulation of hippocampal glutamatergic transmission by ATP is dependent on adenosine a(1) receptors.

Journal: The Journal of pharmacology and experimental therapeutics 20021001

Title: Lack of central effects of peripherally administered adenosine A(1) agonists on synaptic transmission in the rat hippocampus.

Journal: Brain research 20020927

Title: Adenosine A1 receptor modulation of MMP-2 secretion by trabecular meshwork cells.

Journal: Investigative ophthalmology & visual science 20020901

Title: Adenosine-mediated activation of Akt/protein kinase B in the rat hippocampus in vitro and in vivo.

Journal: Neuroscience letters 20020809

Title: Caffeine induces dopamine and glutamate release in the shell of the nucleus accumbens.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20020801

Title: Relationship between bicarbonate and cyclic nucleotide in the promoting effects on head-to-head agglutination in boar spermatozoa.

Journal: Asian journal of andrology 20020601

Title: Adenosine inhibition via A(1) receptor of N-type Ca(2+) current and peptide release from isolated neurohypophysial terminals of the rat.

Journal: The Journal of physiology 20020501

Title: Adenosine inhibits calcium channel currents via A1 receptors on salamander retinal ganglion cells in a mini-slice preparation.

Journal: Journal of neurochemistry 20020501

Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

Journal: The Journal of biological chemistry 20020419

Title: 2-Chloroadenosine, a preferential agonist of adenosine A1 receptors, enhances the anticonvulsant activity of carbamazepine and clonazepam in mice.

Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20020401

Title: Involvement of adenosine A2 receptors in the changes of tissue factor-dependent coagulant activity induced by polymorphonuclear leukocytes in endothelial cells.

Journal: Japanese journal of pharmacology 20020401

Title: Effects of temperature on adenosine A1 receptor activation in guinea pig hippocampus in vitro.

Journal: Pflugers Archiv : European journal of physiology 20020301

Title: Adenosine receptor ligands and cocaine in conditioned place preference (CPP) test in rats.

Journal: Polish journal of pharmacology 20020101

Title: Minoxidil-induced hair growth is mediated by adenosine in cultured dermal papilla cells: possible involvement of sulfonylurea receptor 2B as a target of minoxidil.

Journal: The Journal of investigative dermatology 20011201

Title: Catalepsy and hypolocomotion induced by a nitric oxide donor: attenuation by theophylline.

Journal: European journal of pharmacology 20011130

Title: Anticonvulsant effect of bilateral injection of N6-cyclohexyladenosine into the CA1 region of the hippocampus in amygdala-kindled rats.

Journal: Epilepsy research 20011101

Title: Different activation mechanisms of cystic fibrosis transmembrane conductance regulator expressed in Xenopus laevis oocytes.

Journal: Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20011001

Title: Mechanisms underlying the depression of evoked fast EPSCs following in vitro ischemia in rat hippocampal CA1 neurons.

Journal: Journal of neurophysiology 20010901

Title: Synapse-glia interactions at the mammalian neuromuscular junction.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20010601

Title: Involvement of adenosine in the effect of antidepressants on glutamate and aspartate release in the rat prefrontal cortex.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20010601

Title: Adenosine induces initial hypoxic-ischemic depression of synaptic transmission in the rat hippocampus in vivo.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20010301

Title: The calcium-dependent [3H]acetylcholine release from synaptosomes of brown trout (Salmo trutta) optic tectum is inhibited by adenosine A1 receptors: effects of enucleation on A1 receptor density and cholinergic markers.

Journal: Brain research 20010216

Title: Adenosine-mediated presynaptic modulation of glutamatergic transmission in the laterodorsal tegmentum.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20010201

Title: Distinct modulation of evoked and spontaneous EPSCs by purinoceptors in the nucleus tractus solitarii of the rat.

Journal: The Journal of physiology 20010201

Title: A novel transverse push-pull microprobe: in vitro characterization and in vivo demonstration of the enzymatic production of adenosine in the spinal cord dorsal horn.

Journal: Journal of neurochemistry 20010101

Title: Effect of lactate on the synaptic potential, energy metabolism, calcium homeostasis and extracellular glutamate concentration in the dentate gyrus of the hippocampus from guinea-pig.

Journal: Neuroscience 20010101

Title: Effect of adenosine A1 and A2 receptor stimulation on hypoxia-induced convulsions in adult mice.

Journal: Polish journal of pharmacology 20010101

Title: The CFTR-mediated protein secretion defect: pharmacological correction.

Journal: Pflugers Archiv : European journal of physiology 20010101

Title: Modification of cardiovascular responses to adenosine A1 receptor stimulation in the posterior hypothalamus of anaesthetized rats by cAMP and by GABA(B) receptor blockade.

Journal: Journal of autonomic pharmacology 20010101

Title: Thermodynamics of full agonist, partial agonist, and antagonist binding to wild-type and mutant adenosine A1 receptors.

Journal: Biochemical pharmacology 19981201

Title: Decreased presynaptic sensitivity to adenosine after cocaine withdrawal.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 19981001

Title: Haloperidol-induced catalepsy is influenced by adenosine receptor antagonists.

Journal: Polish journal of pharmacology 19970101

Title: Protection against methamphetamine-induced neurotoxicity to neostriatal dopaminergic neurons by adenosine receptor activation.

Journal: The Journal of pharmacology and experimental therapeutics 19941201

Title: Genistein, an inhibitor of protein tyrosine kinase, is also a competitive antagonist for P1-purinergic (adenosine) receptor in FRTL-5 thyroid cells.

Journal: Biochemical and biophysical research communications 19940930

Title: A threonine residue in the seventh transmembrane domain of the human A1 adenosine receptor mediates specific agonist binding.

Journal: The Journal of biological chemistry 19940128

Title: K A Jacobson, et al. Sulfur-containing 1,3-dialkylxanthine derivatives as selective antagonists at A1-adenosine receptors. J Med Chem. 1989 Aug;32(8):1873-9.

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Tags:35873-49-5 Molecular Formula|35873-49-5 MDL|35873-49-5 SMILES|35873-49-5 8-CYCLOPENTYL-1,3-DIMETHYLXANTHINE