Title: The use of temozolomide for the treatment of malignant tumors: clinical evidence and molecular mechanisms of action.
Journal: Recent patents on anti-cancer drug discovery20101101
Title: Evaluation of the exposure equivalence of oral versus intravenous temozolomide.
Journal: Cancer chemotherapy and pharmacology20100301
Title: Temozolomide: The evidence for its therapeutic efficacy in malignant astrocytomas.
Journal: Core evidence20090101
Title: TMZ-BioShuttle--a reformulated temozolomide.
Journal: International journal of medical sciences20080101
Title: Treatment of glioblastoma multiforme cells with temozolomide-BioShuttle ligated by the inverse Diels-Alder ligation chemistry.
Journal: Drug design, development and therapy20080101
Title: Pharmacokinetic study of temozolomide on a daily-for-5-days schedule in Japanese patients with relapsed malignant gliomas: first study in Asians.
Journal: International journal of clinical oncology20071001
Title: Role of temozolomide in pediatric brain tumors.
Journal: Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery20060701
Title: Development of a pharmacokinetic limited sampling model for temozolomide and its active metabolite MTIC.
Journal: Cancer chemotherapy and pharmacology20050501
Title: Phase I study of temozolomide plus paclitaxel in patients with advanced malignant melanoma and associated in vitro investigations.
Journal: British journal of cancer20050328
Title: Role of temozolomide after radiotherapy for newly diagnosed diffuse brainstem glioma in children: results of a multiinstitutional study (SJHG-98).
Journal: Cancer20050101
Title: Disposition and pharmacokinetics of temozolomide in rat.
Journal: Xenobiotica; the fate of foreign compounds in biological systems20040501
Title: Temozolomide in patients with advanced cancer: phase I and pharmacokinetic study.
Journal: Pharmacotherapy20040101
Title: Dexamethasone protected human glioblastoma U87MG cells from temozolomide induced apoptosis by maintaining Bax:Bcl-2 ratio and preventing proteolytic activities.
Journal: Molecular cancer20040101
Title: Population pharmacokinetics of temozolomide and metabolites in infants and children with primary central nervous system tumors.
Journal: Cancer chemotherapy and pharmacology20031201
Title: Temozolomide induces apoptosis and senescence in glioma cells cultured as multicellular spheroids.
Journal: British journal of cancer20030210
Title: Role of cytochrome P450 isoenzymes in metabolism of O(6)-benzylguanine: implications for dacarbazine activation.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research20011201
Title: Pharmacodynamic-mediated reduction of temozolomide tumor concentrations by the angiogenesis inhibitor TNP-470.
Journal: Cancer research20010715
Title: Validated high-performance liquid chromatographic assay for simultaneous determination of dacarbazine and the plasma metabolites 5-(3-hydroxymethyl-3-methyl-1-triazeno)imidazole-4-carboxamide and 5-(3-methyl-1-triazeno)imidazole-4-carboxamide.
Journal: Journal of chromatography. B, Biomedical sciences and applications20010415
Title: Design of a chimeric 3-methyl-1,2,3-triazene with mixed receptor tyrosine kinase and DNA damaging properties: a novel tumor targeting strategy.
Journal: The Journal of pharmacology and experimental therapeutics20010301
Title: Carcinogenicity of the antineoplastic agent, 5-(3,3-dimethyl-1-triazeno)-imidazole-4-carboxamide, and its metabolites in rats.
Journal: Journal of the National Cancer Institute19750401
